CA2884238C - Crystals of dispiropyrrolidine derivatives - Google Patents

Crystals of dispiropyrrolidine derivatives Download PDF

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Publication number
CA2884238C
CA2884238C CA2884238A CA2884238A CA2884238C CA 2884238 C CA2884238 C CA 2884238C CA 2884238 A CA2884238 A CA 2884238A CA 2884238 A CA2884238 A CA 2884238A CA 2884238 C CA2884238 C CA 2884238C
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Prior art keywords
crystal
ray powder
powder diffraction
diffraction pattern
angstroms
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CA2884238A
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English (en)
French (fr)
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CA2884238A1 (en
Inventor
Shoko Yoshida
Yuuichi Sugimoto
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Daiichi Sankyo Co Ltd
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Daiichi Sankyo Co Ltd
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Publication of CA2884238A1 publication Critical patent/CA2884238A1/en
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
CA2884238A 2012-09-06 2013-09-05 Crystals of dispiropyrrolidine derivatives Active CA2884238C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2012195761 2012-09-06
JP2012-195761 2012-09-06
PCT/JP2013/073865 WO2014038606A1 (ja) 2012-09-06 2013-09-05 ジスピロピロリジン誘導体の結晶

Publications (2)

Publication Number Publication Date
CA2884238A1 CA2884238A1 (en) 2014-03-13
CA2884238C true CA2884238C (en) 2017-10-03

Family

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Family Applications (1)

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CA2884238A Active CA2884238C (en) 2012-09-06 2013-09-05 Crystals of dispiropyrrolidine derivatives

Country Status (12)

Country Link
US (8) US9359368B2 (cg-RX-API-DMAC7.html)
EP (1) EP2894156B1 (cg-RX-API-DMAC7.html)
JP (1) JP6016284B2 (cg-RX-API-DMAC7.html)
KR (1) KR102217410B1 (cg-RX-API-DMAC7.html)
CN (1) CN104812757B (cg-RX-API-DMAC7.html)
BR (1) BR112015004816B1 (cg-RX-API-DMAC7.html)
CA (1) CA2884238C (cg-RX-API-DMAC7.html)
ES (1) ES2637150T3 (cg-RX-API-DMAC7.html)
IN (1) IN2015MN00464A (cg-RX-API-DMAC7.html)
RU (1) RU2647840C2 (cg-RX-API-DMAC7.html)
TW (1) TWI586668B (cg-RX-API-DMAC7.html)
WO (1) WO2014038606A1 (cg-RX-API-DMAC7.html)

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JP2023539663A (ja) 2020-08-28 2023-09-15 アルビナス・オペレーションズ・インコーポレイテッド 急速進行性線維肉腫タンパク質分解化合物及び関連する使用方法
TW202214236A (zh) 2020-09-14 2022-04-16 美商亞文納營運公司 用於靶向降解雌激素受體之化合物之結晶及非晶形形式
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Also Published As

Publication number Publication date
CN104812757A (zh) 2015-07-29
US9359368B2 (en) 2016-06-07
US20180155355A1 (en) 2018-06-07
RU2647840C2 (ru) 2018-03-21
ES2637150T3 (es) 2017-10-11
EP2894156A1 (en) 2015-07-15
US20150210707A1 (en) 2015-07-30
US9884871B2 (en) 2018-02-06
KR102217410B1 (ko) 2021-02-18
KR20150048140A (ko) 2015-05-06
US20170081335A1 (en) 2017-03-23
HK1210172A1 (en) 2016-04-15
US20160244458A1 (en) 2016-08-25
US9540386B2 (en) 2017-01-10
EP2894156B1 (en) 2017-05-17
US20170081336A1 (en) 2017-03-23
BR112015004816B1 (pt) 2022-04-26
CA2884238A1 (en) 2014-03-13
US10030030B2 (en) 2018-07-24
JP6016284B2 (ja) 2016-10-26
TW201410681A (zh) 2014-03-16
US10023578B2 (en) 2018-07-17
US20170081337A1 (en) 2017-03-23
WO2014038606A1 (ja) 2014-03-13
IN2015MN00464A (cg-RX-API-DMAC7.html) 2015-09-04
RU2015112098A (ru) 2016-10-27
BR112015004816A2 (pt) 2017-07-04
CN104812757B (zh) 2016-11-09
US9718831B2 (en) 2017-08-01
US9745315B2 (en) 2017-08-29
JPWO2014038606A1 (ja) 2016-08-12
TWI586668B (zh) 2017-06-11
EP2894156A4 (en) 2016-03-23
US9718830B2 (en) 2017-08-01
US20170081334A1 (en) 2017-03-23
US20180155356A1 (en) 2018-06-07

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