CA2878800A1 - Mycobacterial antigen vaccine - Google Patents

Mycobacterial antigen vaccine Download PDF

Info

Publication number
CA2878800A1
CA2878800A1 CA2878800A CA2878800A CA2878800A1 CA 2878800 A1 CA2878800 A1 CA 2878800A1 CA 2878800 A CA2878800 A CA 2878800A CA 2878800 A CA2878800 A CA 2878800A CA 2878800 A1 CA2878800 A1 CA 2878800A1
Authority
CA
Canada
Prior art keywords
fusion
fusion polypeptide
vector
antigens
anyone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2878800A
Other languages
English (en)
French (fr)
Inventor
Emmanuel TUPIN
Romain MICOL
Charles Antoine COUPET
Genevieve Inchaupse
Marie GOUANVIC
Nathalie Silvestre
Jean-Baptiste Marchand
Cecile Beny
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Transgene SA
Original Assignee
Transgene SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Transgene SA filed Critical Transgene SA
Publication of CA2878800A1 publication Critical patent/CA2878800A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267—Gram-positive bacteria
    • C07K16/1289—Mycobacteriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53—DNA (RNA) vaccination
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pulmonology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CA2878800A 2012-07-10 2013-07-10 Mycobacterial antigen vaccine Abandoned CA2878800A1 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
EP12305825.7 2012-07-10
EP12305825 2012-07-10
EP12306539.3 2012-12-07
EP12306539 2012-12-07
EP13305737 2013-06-03
EP13305737.2 2013-06-03
PCT/EP2013/064624 WO2014009438A2 (en) 2012-07-10 2013-07-10 Mycobacterial antigen vaccine

Publications (1)

Publication Number Publication Date
CA2878800A1 true CA2878800A1 (en) 2014-01-16

Family

ID=48782326

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2878800A Abandoned CA2878800A1 (en) 2012-07-10 2013-07-10 Mycobacterial antigen vaccine

Country Status (16)

Country Link
US (1) US10357555B2 (enExample)
EP (1) EP2872172B1 (enExample)
JP (1) JP6333814B2 (enExample)
KR (1) KR20150058152A (enExample)
CN (1) CN104640564B (enExample)
BR (1) BR112015000530A2 (enExample)
CA (1) CA2878800A1 (enExample)
EA (1) EA029492B1 (enExample)
IL (1) IL236650B (enExample)
MX (1) MX366206B (enExample)
MY (1) MY173004A (enExample)
SG (1) SG11201500171YA (enExample)
TW (1) TWI638829B (enExample)
UA (1) UA119228C2 (enExample)
WO (1) WO2014009438A2 (enExample)
ZA (1) ZA201500784B (enExample)

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KR101631054B1 (ko) * 2015-12-31 2016-06-16 중앙대학교 산학협력단 마이코박테리아 유래 CFP-10 또는 Ag85B에 특이적으로 결합하는 항체 또는 그의 항원 결합 단편
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KR102135328B1 (ko) * 2018-12-19 2020-07-17 대한민국 결핵 2가 항원을 발현하는 약독화된 재조합 백시니아 바이러스 및 이를 포함하는 결핵 예방용 조성물
KR102157770B1 (ko) * 2019-01-11 2020-09-18 주식회사 파이지노믹스 가축의 결핵 진단을 위한 항원 펩타이드 조성물 및 이의 용도
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CN116284283A (zh) * 2021-12-13 2023-06-23 江苏瑞科生物技术股份有限公司 重组结核分枝杆菌抗原、其制备方法和应用
KR102878370B1 (ko) * 2022-06-17 2025-10-31 주식회사 미코라파 면역활성 부위 융합 단백질을 포함하는 결핵 백신 조성물
MA71612A (fr) * 2022-07-29 2025-05-30 University Of Cape Town Constructions de vaccin comprenant des antigènes de tuberculose
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CN116162141B (zh) * 2022-11-30 2024-04-12 中国疾病预防控制中心传染病预防控制所 一种结核分枝杆菌抗原epcra013及其应用
CN116041543B (zh) * 2022-12-07 2023-12-26 中国疾病预防控制中心传染病预防控制所 结核分枝杆菌多抗原融合蛋白及其编码基因和应用
CN116063418B (zh) * 2022-12-08 2024-04-12 中国疾病预防控制中心传染病预防控制所 结核分枝杆菌抗原组合物epdpa015及其制备方法与应用
CN117683141A (zh) * 2023-10-27 2024-03-12 中国疾病预防控制中心传染病预防控制所 结核分枝杆菌多抗原融合蛋白及编码基因和应用
WO2025092548A1 (zh) * 2023-11-03 2025-05-08 烟台派诺生物技术有限公司 一种用于预防结核分枝杆菌感染的纳米颗粒疫苗及其制备方法
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EA201590184A1 (ru) 2015-06-30
UA119228C2 (uk) 2019-05-27
ZA201500784B (en) 2020-07-29
KR20150058152A (ko) 2015-05-28
HK1207962A1 (en) 2016-02-19
MY173004A (en) 2019-12-18
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JP6333814B2 (ja) 2018-05-30
CN104640564A (zh) 2015-05-20
BR112015000530A2 (pt) 2018-08-28
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EP2872172A2 (en) 2015-05-20
WO2014009438A3 (en) 2014-04-10
US10357555B2 (en) 2019-07-23
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EA029492B1 (ru) 2018-04-30
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IL236650B (en) 2019-09-26

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