CA2878478A1 - N-substituted benzamides and methods of use thereof - Google Patents
N-substituted benzamides and methods of use thereof Download PDFInfo
- Publication number
- CA2878478A1 CA2878478A1 CA2878478A CA2878478A CA2878478A1 CA 2878478 A1 CA2878478 A1 CA 2878478A1 CA 2878478 A CA2878478 A CA 2878478A CA 2878478 A CA2878478 A CA 2878478A CA 2878478 A1 CA2878478 A1 CA 2878478A1
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- Prior art keywords
- compound
- group
- pain
- alkyl
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- -1 N-substituted benzamides Chemical class 0.000 title claims description 124
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- 229910052740 iodine Inorganic materials 0.000 claims description 46
- 238000011282 treatment Methods 0.000 claims description 42
- 125000001188 haloalkyl group Chemical group 0.000 claims description 39
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 claims description 38
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 claims description 37
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- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 claims description 5
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- 125000000587 piperidin-1-yl group Chemical group [H]C1([H])N(*)C([H])([H])C([H])([H])C([H])([H])C1([H])[H] 0.000 claims description 2
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Classifications
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- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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-
2013
- 2013-07-05 BR BR112015000187A patent/BR112015000187A2/pt not_active IP Right Cessation
- 2013-07-05 CA CA2878478A patent/CA2878478A1/en not_active Abandoned
- 2013-07-05 US US14/413,218 patent/US10071957B2/en not_active Expired - Fee Related
- 2013-07-05 WO PCT/US2013/049423 patent/WO2014008458A2/en not_active Ceased
- 2013-07-05 EP EP13812904.4A patent/EP2870138B1/en active Active
- 2013-07-05 RU RU2015103913A patent/RU2015103913A/ru not_active Application Discontinuation
- 2013-07-05 JP JP2015520701A patent/JP6309519B2/ja not_active Expired - Fee Related
- 2013-07-05 KR KR1020157002962A patent/KR101663436B1/ko not_active Expired - Fee Related
- 2013-07-05 CN CN201380046120.9A patent/CN104797555B/zh not_active Expired - Fee Related
- 2013-07-05 MX MX2015000164A patent/MX2015000164A/es unknown
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2018
- 2018-08-07 US US16/057,693 patent/US20180346416A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| WO2014008458A2 (en) | 2014-01-09 |
| US20180346416A1 (en) | 2018-12-06 |
| WO2014008458A3 (en) | 2014-04-17 |
| JP2015523369A (ja) | 2015-08-13 |
| BR112015000187A2 (pt) | 2017-06-27 |
| CN104797555A (zh) | 2015-07-22 |
| RU2015103913A (ru) | 2016-08-27 |
| EP2870138A2 (en) | 2015-05-13 |
| MX2015000164A (es) | 2015-08-12 |
| US20150322002A1 (en) | 2015-11-12 |
| EP2870138A4 (en) | 2016-02-17 |
| US10071957B2 (en) | 2018-09-11 |
| JP6309519B2 (ja) | 2018-04-11 |
| KR20150036367A (ko) | 2015-04-07 |
| CN104797555B (zh) | 2017-12-22 |
| HK1209736A1 (en) | 2016-04-08 |
| EP2870138B1 (en) | 2018-08-22 |
| KR101663436B1 (ko) | 2016-10-06 |
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