CA2878344A1 - Complexes of cytomegalovirus proteins - Google Patents
Complexes of cytomegalovirus proteins Download PDFInfo
- Publication number
- CA2878344A1 CA2878344A1 CA2878344A CA2878344A CA2878344A1 CA 2878344 A1 CA2878344 A1 CA 2878344A1 CA 2878344 A CA2878344 A CA 2878344A CA 2878344 A CA2878344 A CA 2878344A CA 2878344 A1 CA2878344 A1 CA 2878344A1
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- Prior art keywords
- hcmv
- seq
- membrane protein
- complex
- protein complex
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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- C12N2710/00011—Details
- C12N2710/16011—Herpesviridae
- C12N2710/16111—Cytomegalovirus, e.g. human herpesvirus 5
- C12N2710/16151—Methods of production or purification of viral material
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Microbiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Molecular Biology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Biotechnology (AREA)
- Gastroenterology & Hepatology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Tropical Medicine & Parasitology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201261668975P | 2012-07-06 | 2012-07-06 | |
| US61/668,975 | 2012-07-06 | ||
| US201361770257P | 2013-02-27 | 2013-02-27 | |
| US61/770,257 | 2013-02-27 | ||
| PCT/EP2013/063750 WO2014005959A1 (en) | 2012-07-06 | 2013-06-29 | Complexes of cytomegalovirus proteins |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2878344A1 true CA2878344A1 (en) | 2014-01-09 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2878344A Abandoned CA2878344A1 (en) | 2012-07-06 | 2013-06-29 | Complexes of cytomegalovirus proteins |
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| EP (1) | EP2869843B1 (enExample) |
| JP (3) | JP2015522581A (enExample) |
| KR (1) | KR20150031322A (enExample) |
| CN (1) | CN104853771A (enExample) |
| AU (1) | AU2013286093B2 (enExample) |
| CA (1) | CA2878344A1 (enExample) |
| ES (1) | ES2753138T3 (enExample) |
| GB (1) | GB2513768B (enExample) |
| HK (1) | HK1210037A1 (enExample) |
| IL (1) | IL236261A0 (enExample) |
| IN (1) | IN2014KN02929A (enExample) |
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| RU (1) | RU2015103891A (enExample) |
| SG (1) | SG11201408328VA (enExample) |
| WO (1) | WO2014005959A1 (enExample) |
| ZA (1) | ZA201409364B (enExample) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CA2878344A1 (en) | 2012-07-06 | 2014-01-09 | Novartis Ag | Complexes of cytomegalovirus proteins |
| AU2013293570B2 (en) | 2012-07-27 | 2019-05-23 | City Of Hope | An MVA vaccine for delivery of a UL128 complex and preventing CMV infection |
| EP3052106A4 (en) | 2013-09-30 | 2017-07-19 | ModernaTX, Inc. | Polynucleotides encoding immune modulating polypeptides |
| ES2868427T3 (es) * | 2013-12-03 | 2021-10-21 | Hookipa Biotech Ag | Vacunas contra el CMV |
| AU2015251221A1 (en) * | 2014-04-23 | 2016-10-27 | CARIPLO, Fondazione | Human cytomegalovirus vaccine compositions and method of producing the same |
| WO2015165480A1 (en) * | 2014-04-30 | 2015-11-05 | Institute For Research In Biomedicine | Human cytomegalovirus vaccine compositions and method of producing the same |
| BR112016025792A2 (pt) * | 2014-05-08 | 2017-10-17 | Pfizer | meios e processos para tratamento de cmv |
| EP3015475A1 (en) * | 2014-10-31 | 2016-05-04 | Novartis AG | Mammalian cells expressing cytomegalovirus antigens |
| EP3048114A1 (en) | 2015-01-22 | 2016-07-27 | Novartis AG | Cytomegalovirus antigens and uses thereof |
| EP3047856A1 (en) * | 2015-01-23 | 2016-07-27 | Novartis AG | Cmv antigens and uses thereof |
| EP3347045A4 (en) | 2015-09-10 | 2019-08-28 | City of Hope | MVA-GH / GL-PC VACCINATED ANTIBODIES FOR NEUTRALIZING THE INFECTIOSITY OF HUMAN CYTOMEGALOVIRUS AND METHOD THEREFOR |
| WO2017070613A1 (en) | 2015-10-22 | 2017-04-27 | Modernatx, Inc. | Human cytomegalovirus vaccine |
| AU2017207744A1 (en) | 2016-01-11 | 2018-07-26 | Verndari, Inc. | Microneedle compositions and methods of using same |
| US10611800B2 (en) | 2016-03-11 | 2020-04-07 | Pfizer Inc. | Human cytomegalovirus gB polypeptide |
| EP3528821A4 (en) | 2016-10-21 | 2020-07-01 | ModernaTX, Inc. | HUMAN CYTOMEGALOVIRUS VACCINE |
| AU2018213378B2 (en) * | 2017-01-27 | 2025-03-06 | The Henry M. Jackson Foundation For The Advancement Of Military Medicine, Inc. | Vaccine compositions of herpesvirus envelope protein combinations to induce immune response |
| WO2018187325A1 (en) | 2017-04-04 | 2018-10-11 | University Of Washington | Self-assembling protein nanostructures displaying paramyxovirus and/or pneumovirus f proteins and their use |
| WO2018193307A1 (en) | 2017-04-19 | 2018-10-25 | Glaxosmithkline Biologicals Sa | Modified cytomegalovirus proteins and stabilized complexes |
| EP3658581A1 (en) * | 2017-07-24 | 2020-06-03 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Antibodies and peptides to treat hcmv related diseases |
| MA49693A (fr) | 2017-07-28 | 2020-06-03 | Janssen Vaccines & Prevention Bv | Méthodes et compositions pour assurer l'immunisation contre l'arnrep hétérologue |
| BR112020004747A2 (pt) | 2017-09-13 | 2020-09-24 | Sanofi Pasteur | composição imunogênica de citomegalovírus humano |
| KR20200138234A (ko) | 2018-02-28 | 2020-12-09 | 유니버시티 오브 워싱톤 | 자기 조립 나노구조 백신 |
| SG11202010821TA (en) | 2018-05-04 | 2020-11-27 | Spybiotech Ltd | Vaccine composition |
| CA3116175A1 (en) * | 2018-10-17 | 2020-04-23 | Glaxosmithkline Biologicals Sa | Modified cytomegalovirus proteins and stabilized complexes |
| JP7179872B2 (ja) | 2018-12-10 | 2022-11-29 | Ｋｍバイオロジクス株式会社 | サイトメガロウイルスの先天性感染を予防又は治療するためのワクチン |
| US11629172B2 (en) | 2018-12-21 | 2023-04-18 | Pfizer Inc. | Human cytomegalovirus gB polypeptide |
| WO2021014385A1 (en) | 2019-07-24 | 2021-01-28 | Glaxosmithkline Biologicals Sa | Modified human cytomegalovirus proteins |
| CA3186423C (en) * | 2020-06-09 | 2024-03-19 | Km Biologics Co., Ltd. | Fusion protein of pentamer and gb of cytomegalovirus, and vaccine containing said fusion protein |
| US11857622B2 (en) | 2020-06-21 | 2024-01-02 | Pfizer Inc. | Human cytomegalovirus GB polypeptide |
| US11406703B2 (en) | 2020-08-25 | 2022-08-09 | Modernatx, Inc. | Human cytomegalovirus vaccine |
| KR20230097028A (ko) | 2020-10-28 | 2023-06-30 | 사노피 파스퇴르 | Tlr4 효현제를 함유하는 리포좀, 이의 제조 및 용도 |
| MX2023009891A (es) * | 2021-02-24 | 2023-11-22 | Pfizer | Nuevas regiones susceptibles a modificarse por fármacos en el polipéptido de glucoproteína b del citomegalovirus humano y métodos de uso de las mismas. |
| US20250101067A1 (en) | 2022-01-28 | 2025-03-27 | Glaxosmithkline Biologicals Sa | Modified human cytomegalovirus proteins |
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|---|---|---|---|---|
| EP1201757A3 (en) | 1988-12-22 | 2002-09-11 | Genentech, Inc. | Method for preparing water soluble polypeptides |
| US5364780A (en) | 1989-03-17 | 1994-11-15 | E. I. Du Pont De Nemours And Company | External regulation of gene expression by inducible promoters |
| JPH06501845A (ja) | 1990-08-02 | 1994-03-03 | カイロン コーポレイション | バキュロウイルス―昆虫細胞発現システムを用いたヒトｃｍｖ糖タンパク質―ｈの発現 |
| US5474914A (en) | 1992-07-29 | 1995-12-12 | Chiron Corporation | Method of producing secreted CMV glycoprotein H |
| US5362865A (en) | 1993-09-02 | 1994-11-08 | Monsanto Company | Enhanced expression in plants using non-translated leader sequences |
| US5693506A (en) | 1993-11-16 | 1997-12-02 | The Regents Of The University Of California | Process for protein production in plants |
| US5815900A (en) | 1995-03-06 | 1998-10-06 | Matsushita Electric Industrial Co., Ltd. | Method of manufacturing a surface acoustic wave module |
| WO2004076645A2 (en) * | 2003-02-27 | 2004-09-10 | University Of Massachusetts | Compositions and methods for cytomegalovirus treatment |
| CA2654563A1 (en) | 2006-06-07 | 2007-12-21 | The Trustees Of Princeton University | Cytomegalovirus surface protein complex for use in vaccines and as a drug target |
| US7947274B2 (en) * | 2007-01-04 | 2011-05-24 | Humabs, LLC. | Human cytomegalovirus neutralising antibodies and use thereof |
| US9439960B2 (en) | 2007-10-10 | 2016-09-13 | The Trustees Of Princeton University | Cytomegalovirus vaccines and methods of production |
| BR112012004806B8 (pt) | 2009-09-02 | 2022-10-04 | Novartis Ag | composições imunogênicas que incluem moduladores da atividade de tlr, método para aumento da eficácia da referida composição e uso |
| US9089537B2 (en) * | 2010-02-26 | 2015-07-28 | The Trustees Of The University Of Pennslyvania | Subunit vaccines for herpes viruses and methods of use |
| EP3449910A1 (en) | 2010-07-06 | 2019-03-06 | GlaxoSmithKline Biologicals S.A. | Cationic oil-in-water emulsions |
| HUE026646T2 (en) | 2010-07-06 | 2016-07-28 | Glaxosmithkline Biologicals Sa | Preferred liposomes containing lipids of PKA value for delivery of RNA |
| WO2012015211A2 (ko) | 2010-07-30 | 2012-02-02 | 주식회사종근당 | 사이클로스포린 에이 함유 점안제 조성물 |
| US20130164289A1 (en) * | 2010-09-09 | 2013-06-27 | Virginia Commonwealth University | Human cytomegalovirus vaccine |
| CN103269713B (zh) * | 2010-10-11 | 2016-01-20 | 诺华有限公司 | 抗原递送平台 |
| US9243041B2 (en) | 2011-01-31 | 2016-01-26 | The Trustees Of The University Of Pennsylvania | Nucleic acid molecules encoding novel herpes antigens, vaccine comprising the same, and methods of use thereof |
| EP3508219A1 (en) | 2011-07-06 | 2019-07-10 | GlaxoSmithKline Biologicals S.A. | Self-replicating rna prime - protein boost vaccines |
| EP3456316A1 (en) * | 2011-07-06 | 2019-03-20 | GlaxoSmithKline Biologicals S.A. | Cationic oil-in-water emulsions |
| HUE041800T2 (hu) * | 2011-08-31 | 2019-05-28 | Glaxosmithkline Biologicals Sa | Pegilált liposzómák immunogént kódoló RNS bejuttatására |
| CA2878344A1 (en) | 2012-07-06 | 2014-01-09 | Novartis Ag | Complexes of cytomegalovirus proteins |
| EP3015475A1 (en) | 2014-10-31 | 2016-05-04 | Novartis AG | Mammalian cells expressing cytomegalovirus antigens |
-
2013
- 2013-06-29 CA CA2878344A patent/CA2878344A1/en not_active Abandoned
- 2013-06-29 WO PCT/EP2013/063750 patent/WO2014005959A1/en not_active Ceased
- 2013-06-29 RU RU2015103891A patent/RU2015103891A/ru not_active Application Discontinuation
- 2013-06-29 CN CN201380036145.0A patent/CN104853771A/zh active Pending
- 2013-06-29 AU AU2013286093A patent/AU2013286093B2/en not_active Ceased
- 2013-06-29 IN IN2929KON2014 patent/IN2014KN02929A/en unknown
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- 2013-06-29 MX MX2018000675A patent/MX378747B/es unknown
- 2013-06-29 SG SG11201408328VA patent/SG11201408328VA/en unknown
- 2013-06-29 KR KR1020157002267A patent/KR20150031322A/ko not_active Withdrawn
- 2013-06-29 MX MX2014015496A patent/MX355469B/es active IP Right Grant
- 2013-06-29 GB GB1413863.0A patent/GB2513768B/en active Active
- 2013-06-29 US US14/410,461 patent/US9683022B2/en active Active
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- 2013-06-29 HK HK15110880.5A patent/HK1210037A1/xx unknown
- 2013-06-29 EP EP13736518.5A patent/EP2869843B1/en active Active
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2014
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- 2014-12-18 ZA ZA2014/09364A patent/ZA201409364B/en unknown
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2019
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2021
- 2021-12-15 US US17/551,867 patent/US20220106364A1/en not_active Abandoned
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| US20170320916A1 (en) | 2017-11-09 |
| MX2014015496A (es) | 2015-03-06 |
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| US9683022B2 (en) | 2017-06-20 |
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| US20160159864A1 (en) | 2016-06-09 |
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| AU2013286093B2 (en) | 2018-01-04 |
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| AU2013286093A1 (en) | 2015-02-12 |
| SG11201408328VA (en) | 2015-02-27 |
| JP2015522581A (ja) | 2015-08-06 |
| JP2017192400A (ja) | 2017-10-26 |
| ES2753138T3 (es) | 2020-04-07 |
| US20190211064A1 (en) | 2019-07-11 |
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| US20220106364A1 (en) | 2022-04-07 |
| EP2869843B1 (en) | 2019-08-07 |
| WO2014005959A1 (en) | 2014-01-09 |
| US10287322B2 (en) | 2019-05-14 |
| CN104853771A (zh) | 2015-08-19 |
| HK1210037A1 (en) | 2016-04-15 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |
Effective date: 20190702 |