CA2864995C - Ingenol derivatives in the reactivation of latent hiv virus - Google Patents
Ingenol derivatives in the reactivation of latent hiv virus Download PDFInfo
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- CA2864995C CA2864995C CA2864995A CA2864995A CA2864995C CA 2864995 C CA2864995 C CA 2864995C CA 2864995 A CA2864995 A CA 2864995A CA 2864995 A CA2864995 A CA 2864995A CA 2864995 C CA2864995 C CA 2864995C
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Landscapes
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| BR102012006549A BR102012006549A2 (pt) | 2012-03-23 | 2012-03-23 | uso de um ou mais derivados de ingenol, associação farmacêutica, composição farmacêutica, adjuvante, método de tratamento e método para a reativação do vírus hiv latente |
| BRBR1020120065495 | 2012-03-23 | ||
| PCT/BR2013/000063 WO2013126980A1 (pt) | 2012-03-02 | 2013-03-01 | Derivados de ingenol na reativação de vírus hiv latente |
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| WO2016022358A1 (en) | 2014-08-08 | 2016-02-11 | The Regents Of The University Of California | Compositions and methods for reactivating latent viral infections |
| WO2016177833A1 (en) | 2015-05-04 | 2016-11-10 | Bionor Immuno As | Dosage regimen for hiv vaccine |
| WO2016191836A1 (pt) * | 2015-06-03 | 2016-12-08 | Amazônia Fitomedicamentos Ltda. | Método de preparação de ingenol-3-dodecanoato, método de preparação de 3-etinil-3-hidroxi-4.7.7-trimetilbiciclo[4.1.0]heptano-2-carbaldeído e método de preparação de 2,2-dimetil-4-etinil-5-trifenilfosforanilideno-1,3-dioxano |
| WO2016191837A1 (pt) * | 2015-06-03 | 2016-12-08 | Amazônia Fitomedicamentos Ltda. | Método de preparação de ingenol-3-hexanoato, método de preparação de 3-etinil-3-hidroxi-4.7.7-trimetilbiciclo[4.1.0]heptano-2-carbaldeído e método de preparação do composto 2,2-dimetil-4-etinil-5-trifenilfosforanilideno-1,3-dioxano |
| CN105079323B (zh) * | 2015-09-15 | 2019-08-23 | 北京工业大学 | 几种中药提取物在hiv潜伏再激活治疗中的应用 |
| CN106928063B (zh) * | 2015-12-31 | 2020-09-01 | 上海鑫昊生物科技有限公司 | 巨大戟二萜醇类化合物及其在抗hiv潜伏治疗上的应用 |
| WO2017130156A1 (en) | 2016-01-27 | 2017-08-03 | Glaxosmithkline Intellectual Property (No.2) Limited | Ingenol analogs, pharmaceutical compositions and methods of use thereof |
| CN109912419A (zh) * | 2017-12-13 | 2019-06-21 | 复旦大学 | 巨大戟烷型二萜及其在制备抗艾滋病毒药物中的用途 |
| CN110251495B (zh) * | 2018-03-12 | 2022-05-31 | 重庆医科大学 | 20-脱氧巨大戟二萜醇在制备抑制hbv复制的药物中的应用 |
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| JP2003171349A (ja) * | 2001-08-06 | 2003-06-20 | Univ Nihon | 新規なジテルペン類、及びこれを用いた組成物、抗炎症剤、抗癌剤 |
| WO2006116897A1 (fr) * | 2005-04-30 | 2006-11-09 | Nihon University | Diterpenes provenant de euphorbia kansui et leur utilisation |
| BRPI0520394A2 (pt) * | 2005-06-28 | 2009-05-05 | Amazonia Fitomedicamentos Ltda | fração ativa de um extrato de látex de euphorbia tirucalli l. com um solvente polar, uso de um ativo de um extrato de euphorbia tirucalli l. com solvente polar, uso de um ou mais compostos de 3-(2,4,6-dodecatrienoil)-ingenol e 3-(2,4,6,8-tetradecatetranoil)-ingenol, composição , uso da composição e processo para obtenção de uma fração ativa de um extrato de euphorbia tirucalli l. com solvente polar |
| BRPI0810806A2 (pt) | 2007-04-30 | 2014-10-29 | Peplin Research Pty Ltd | Método para tratar uma lesão cutânea em um indivíduo |
| WO2011086424A1 (en) | 2010-01-15 | 2011-07-21 | Amazonia Fitomedicamentos Ltda | Pharmaceutical use of multicyclic compounds mixtures as concomitant anti-cancer, anti-inflammatory and anti-pain agents |
| US20120289487A1 (en) * | 2010-01-15 | 2012-11-15 | Amazônia Fitomedicamentos Ltda | Pharmaceutical Use of Multicyclic Compounds as Anti-Aids Agents |
-
2013
- 2013-03-01 AU AU2013225633A patent/AU2013225633B2/en not_active Ceased
- 2013-03-01 WO PCT/BR2013/000063 patent/WO2013126980A1/pt not_active Ceased
- 2013-03-01 US US14/382,060 patent/US10105339B2/en not_active Expired - Fee Related
- 2013-03-01 MX MX2014010463A patent/MX359300B/es active IP Right Grant
- 2013-03-01 CN CN201380012133.4A patent/CN104136081B/zh not_active Expired - Fee Related
- 2013-03-01 CA CA2864995A patent/CA2864995C/en not_active Expired - Fee Related
- 2013-03-01 IN IN1911MUN2014 patent/IN2014MN01911A/en unknown
- 2013-03-01 RU RU2014139825A patent/RU2609512C2/ru not_active IP Right Cessation
- 2013-03-01 JP JP2014559040A patent/JP6280510B2/ja not_active Expired - Fee Related
- 2013-03-01 ES ES13754607.3T patent/ES2683726T3/es active Active
- 2013-03-01 EP EP13754607.3A patent/EP2821105B1/en not_active Not-in-force
- 2013-03-01 NZ NZ628408A patent/NZ628408A/en not_active IP Right Cessation
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2014
- 2014-09-01 IL IL234404A patent/IL234404A/en active IP Right Grant
Also Published As
| Publication number | Publication date |
|---|---|
| CN104136081A (zh) | 2014-11-05 |
| HK1203872A1 (en) | 2015-11-06 |
| MX359300B (es) | 2018-09-21 |
| IN2014MN01911A (enExample) | 2015-07-10 |
| JP6280510B2 (ja) | 2018-02-14 |
| CN104136081B (zh) | 2018-05-15 |
| EP2821105A4 (en) | 2015-11-04 |
| EP2821105A8 (en) | 2015-04-29 |
| CA2864995A1 (en) | 2013-09-06 |
| AU2013225633A1 (en) | 2014-08-28 |
| NZ628408A (en) | 2017-09-29 |
| IL234404A (en) | 2017-09-28 |
| EP2821105A1 (en) | 2015-01-07 |
| US20150030638A1 (en) | 2015-01-29 |
| MX2014010463A (es) | 2014-10-13 |
| EP2821105B1 (en) | 2018-05-23 |
| RU2609512C2 (ru) | 2017-02-02 |
| AU2013225633B2 (en) | 2017-11-23 |
| RU2014139825A (ru) | 2016-04-20 |
| WO2013126980A1 (pt) | 2013-09-06 |
| ES2683726T3 (es) | 2018-09-27 |
| JP2015508782A (ja) | 2015-03-23 |
| US10105339B2 (en) | 2018-10-23 |
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