CA2840977A1 - Liposomes having useful n:p ratio for delivery of rna molecules - Google Patents
Liposomes having useful n:p ratio for delivery of rna molecules Download PDFInfo
- Publication number
- CA2840977A1 CA2840977A1 CA2840977A CA2840977A CA2840977A1 CA 2840977 A1 CA2840977 A1 CA 2840977A1 CA 2840977 A CA2840977 A CA 2840977A CA 2840977 A CA2840977 A CA 2840977A CA 2840977 A1 CA2840977 A1 CA 2840977A1
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- rna
- liposome
- immunogen
- virus
- ratio
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- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
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- C—CHEMISTRY; METALLURGY
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C—CHEMISTRY; METALLURGY
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- C12N2770/36141—Use of virus, viral particle or viral elements as a vector
- C12N2770/36143—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
Landscapes
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- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
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|---|---|---|---|
| US201161505088P | 2011-07-06 | 2011-07-06 | |
| US61/505,088 | 2011-07-06 | ||
| PCT/US2012/045829 WO2013006825A1 (en) | 2011-07-06 | 2012-07-06 | Liposomes having useful n:p ratio for delivery of rna molecules |
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| CA2840977A1 true CA2840977A1 (en) | 2013-01-10 |
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| CA2840977A Abandoned CA2840977A1 (en) | 2011-07-06 | 2012-07-06 | Liposomes having useful n:p ratio for delivery of rna molecules |
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| FI4005592T3 (fi) | 2010-07-06 | 2023-01-13 | Virionin kaltaisia kuljetuspartikkeleita itsereplikoituville rna-molekyyleille | |
| CN103153284B (zh) | 2010-07-06 | 2015-11-25 | 诺华股份有限公司 | 含有其pKa值有利于RNA递送的脂质的脂质体 |
| PT3243526T (pt) | 2010-07-06 | 2020-03-04 | Glaxosmithkline Biologicals Sa | Distribuição de arn para despoletar múltiplas vias imunitárias |
| US10487332B2 (en) | 2010-07-06 | 2019-11-26 | Glaxosmithkline Biologicals Sa | Immunisation of large mammals with low doses of RNA |
| CA2807552A1 (en) | 2010-08-06 | 2012-02-09 | Moderna Therapeutics, Inc. | Engineered nucleic acids and methods of use thereof |
| JP5911870B2 (ja) | 2010-08-31 | 2016-04-27 | ノバルティス アーゲー | 免疫原をコードするｒｎａの送達のためのｐｅｇ化リポソーム |
| RS63890B1 (sr) * | 2010-08-31 | 2023-02-28 | Glaxosmithkline Biologicals Sa | Mali lipozomi za isporuku rnk koja kodira imunogen |
| EP2857499A1 (en) | 2010-10-01 | 2015-04-08 | Moderna Therapeutics, Inc. | Engineered nucleic acids and methods of use thereof |
| KR102266691B1 (ko) | 2010-10-11 | 2021-06-23 | 노파르티스 아게 | 항원 전달 플랫폼 |
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| KR20220025112A (ko) | 2011-06-08 | 2022-03-03 | 샤이어 휴먼 지네틱 테라피즈 인크. | Mrna 전달을 위한 지질 나노입자 조성물 및 방법 |
| RU2014104090A (ru) | 2011-07-06 | 2015-08-20 | Новартис Аг | Липосомы с эффективным соотношением n:p для доставки молекул phk |
| JP2014522842A (ja) | 2011-07-06 | 2014-09-08 | ノバルティス アーゲー | 免疫原性組み合わせ組成物およびその使用 |
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-
2012
- 2012-07-06 RU RU2014104090/10A patent/RU2014104090A/ru not_active Application Discontinuation
- 2012-07-06 BR BR112014000236A patent/BR112014000236A2/pt not_active Application Discontinuation
- 2012-07-06 CN CN201280033241.5A patent/CN103764121A/zh active Pending
- 2012-07-06 MX MX2014000053A patent/MX350764B/es active IP Right Grant
- 2012-07-06 ES ES12738679T patent/ES2861428T3/es active Active
- 2012-07-06 EP EP20214948.0A patent/EP3821879A1/en not_active Withdrawn
- 2012-07-06 EP EP12738679.5A patent/EP2729126B1/en not_active Revoked
- 2012-07-06 US US14/130,748 patent/US20140141070A1/en not_active Abandoned
- 2012-07-06 WO PCT/US2012/045829 patent/WO2013006825A1/en not_active Ceased
- 2012-07-06 SG SG10201605537XA patent/SG10201605537XA/en unknown
- 2012-07-06 EP EP21208072.5A patent/EP4014966A1/en not_active Withdrawn
- 2012-07-06 EP EP22192470.7A patent/EP4115875A1/en not_active Withdrawn
- 2012-07-06 CA CA2840977A patent/CA2840977A1/en not_active Abandoned
- 2012-07-06 EP EP22192474.9A patent/EP4115876A1/en not_active Withdrawn
- 2012-07-06 JP JP2014519084A patent/JP2014520806A/ja active Pending
-
2016
- 2016-10-12 JP JP2016200593A patent/JP2017002088A/ja active Pending
-
2019
- 2019-12-16 US US16/714,891 patent/US20200113831A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP2729126A1 (en) | 2014-05-14 |
| WO2013006825A1 (en) | 2013-01-10 |
| EP4014966A1 (en) | 2022-06-22 |
| US20140141070A1 (en) | 2014-05-22 |
| RU2014104090A (ru) | 2015-08-20 |
| EP4115875A1 (en) | 2023-01-11 |
| JP2014520806A (ja) | 2014-08-25 |
| EP2729126B1 (en) | 2020-12-23 |
| EP3821879A1 (en) | 2021-05-19 |
| EP4115876A1 (en) | 2023-01-11 |
| SG10201605537XA (en) | 2016-09-29 |
| JP2017002088A (ja) | 2017-01-05 |
| CN103764121A (zh) | 2014-04-30 |
| ES2861428T3 (es) | 2021-10-06 |
| US20200113831A1 (en) | 2020-04-16 |
| MX2014000053A (es) | 2014-04-30 |
| BR112014000236A2 (pt) | 2017-02-14 |
| MX350764B (es) | 2017-09-18 |
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Legal Events
| Date | Code | Title | Description |
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| EEER | Examination request |
Effective date: 20170705 |
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| FZDE | Discontinued |
Effective date: 20191206 |