CA2832910C - Compositions and methods for preventing or treating diseases, conditions, or processes characterized by aberrant fibroblast proliferation and extracellular matrix deposition - Google Patents

Compositions and methods for preventing or treating diseases, conditions, or processes characterized by aberrant fibroblast proliferation and extracellular matrix deposition Download PDF

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Publication number
CA2832910C
CA2832910C CA2832910A CA2832910A CA2832910C CA 2832910 C CA2832910 C CA 2832910C CA 2832910 A CA2832910 A CA 2832910A CA 2832910 A CA2832910 A CA 2832910A CA 2832910 C CA2832910 C CA 2832910C
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Canada
Prior art keywords
kinase
another embodiment
lung
polypeptide
seq
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2832910A
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English (en)
French (fr)
Other versions
CA2832910A1 (en
Inventor
Cynthia Lander
Colleen Brophy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Moerae Matrix Inc
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Moerae Matrix Inc
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Publication date
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Priority to CA3042808A priority Critical patent/CA3042808A1/en
Publication of CA2832910A1 publication Critical patent/CA2832910A1/en
Application granted granted Critical
Publication of CA2832910C publication Critical patent/CA2832910C/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/21—Interferons [IFN]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pulmonology (AREA)
  • Biomedical Technology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
CA2832910A 2011-04-12 2012-04-12 Compositions and methods for preventing or treating diseases, conditions, or processes characterized by aberrant fibroblast proliferation and extracellular matrix deposition Expired - Fee Related CA2832910C (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CA3042808A CA3042808A1 (en) 2011-04-12 2012-04-12 Compositions and methods for preventing or treating diseases, conditions, or processes characterized by aberrant fibroblast proliferation and extracellular matrix deposition

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201161474370P 2011-04-12 2011-04-12
US61/474,370 2011-04-12
PCT/US2012/033368 WO2012142320A2 (en) 2011-04-12 2012-04-12 Compositions and methods for preventing or treating diseases, conditions, or processes characterized by aberrant fibroblast proliferation and extracellular matrix deposition

Related Child Applications (1)

Application Number Title Priority Date Filing Date
CA3042808A Division CA3042808A1 (en) 2011-04-12 2012-04-12 Compositions and methods for preventing or treating diseases, conditions, or processes characterized by aberrant fibroblast proliferation and extracellular matrix deposition

Publications (2)

Publication Number Publication Date
CA2832910A1 CA2832910A1 (en) 2012-10-18
CA2832910C true CA2832910C (en) 2019-07-02

Family

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Family Applications (2)

Application Number Title Priority Date Filing Date
CA2832910A Expired - Fee Related CA2832910C (en) 2011-04-12 2012-04-12 Compositions and methods for preventing or treating diseases, conditions, or processes characterized by aberrant fibroblast proliferation and extracellular matrix deposition
CA3042808A Abandoned CA3042808A1 (en) 2011-04-12 2012-04-12 Compositions and methods for preventing or treating diseases, conditions, or processes characterized by aberrant fibroblast proliferation and extracellular matrix deposition

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA3042808A Abandoned CA3042808A1 (en) 2011-04-12 2012-04-12 Compositions and methods for preventing or treating diseases, conditions, or processes characterized by aberrant fibroblast proliferation and extracellular matrix deposition

Country Status (15)

Country Link
US (2) US9642888B2 (enExample)
EP (1) EP2696888B1 (enExample)
JP (1) JP6031510B2 (enExample)
KR (1) KR101862291B1 (enExample)
CN (3) CN108014340A (enExample)
AU (1) AU2012242768B2 (enExample)
BR (1) BR112013026313A8 (enExample)
CA (2) CA2832910C (enExample)
DK (1) DK2696888T3 (enExample)
ES (1) ES2711670T3 (enExample)
HK (1) HK1255005A1 (enExample)
MX (1) MX359516B (enExample)
RU (1) RU2620066C2 (enExample)
SG (2) SG194135A1 (enExample)
WO (1) WO2012142320A2 (enExample)

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Also Published As

Publication number Publication date
KR20140063517A (ko) 2014-05-27
CN108014340A (zh) 2018-05-11
US9642888B2 (en) 2017-05-09
NZ616672A (en) 2016-04-29
SG10201604560TA (en) 2016-07-28
BR112013026313A8 (pt) 2018-01-30
WO2012142320A8 (en) 2014-02-20
EP2696888B1 (en) 2018-12-05
EP2696888A2 (en) 2014-02-19
DK2696888T3 (en) 2019-03-25
AU2012242768B2 (en) 2017-10-12
CA2832910A1 (en) 2012-10-18
JP2014533235A (ja) 2014-12-11
JP6031510B2 (ja) 2016-11-24
HK1255005A1 (zh) 2019-08-02
WO2012142320A3 (en) 2015-06-11
US20190022169A1 (en) 2019-01-24
CN111110850A (zh) 2020-05-08
CN104302310A (zh) 2015-01-21
BR112013026313A2 (pt) 2016-12-27
RU2620066C2 (ru) 2017-05-22
MX2013011771A (es) 2014-07-30
MX359516B (es) 2018-10-01
KR101862291B1 (ko) 2018-05-29
WO2012142320A2 (en) 2012-10-18
CA3042808A1 (en) 2012-10-18
US20120263680A1 (en) 2012-10-18
EP2696888A4 (en) 2016-04-20
RU2013150249A (ru) 2015-05-20
AU2012242768A1 (en) 2013-10-24
SG194135A1 (en) 2013-11-29
ES2711670T3 (es) 2019-05-06

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