BR112013026313A8 - composições e métodos para prevenir ou tratar doenças, condições ou processos caracterizados por proliferação anormal de fibroblastos e depósito de matriz extracelular - Google Patents
composições e métodos para prevenir ou tratar doenças, condições ou processos caracterizados por proliferação anormal de fibroblastos e depósito de matriz extracelularInfo
- Publication number
- BR112013026313A8 BR112013026313A8 BR112013026313A BR112013026313A BR112013026313A8 BR 112013026313 A8 BR112013026313 A8 BR 112013026313A8 BR 112013026313 A BR112013026313 A BR 112013026313A BR 112013026313 A BR112013026313 A BR 112013026313A BR 112013026313 A8 BR112013026313 A8 BR 112013026313A8
- Authority
- BR
- Brazil
- Prior art keywords
- compositions
- preventing
- conditions
- methods
- extracellular matrix
- Prior art date
Links
- 102000010834 Extracellular Matrix Proteins Human genes 0.000 title 1
- 108010037362 Extracellular Matrix Proteins Proteins 0.000 title 1
- 230000002159 abnormal effect Effects 0.000 title 1
- 230000008021 deposition Effects 0.000 title 1
- 201000010099 disease Diseases 0.000 title 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 title 1
- 210000002744 extracellular matrix Anatomy 0.000 title 1
- 210000002950 fibroblast Anatomy 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 230000035755 proliferation Effects 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/10—Peptides having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/21—Interferons [IFN]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Zoology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pulmonology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201161474370P | 2011-04-12 | 2011-04-12 | |
| PCT/US2012/033368 WO2012142320A2 (en) | 2011-04-12 | 2012-04-12 | Compositions and methods for preventing or treating diseases, conditions, or processes characterized by aberrant fibroblast proliferation and extracellular matrix deposition |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| BR112013026313A2 BR112013026313A2 (pt) | 2016-12-27 |
| BR112013026313A8 true BR112013026313A8 (pt) | 2018-01-30 |
Family
ID=47006527
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BR112013026313A BR112013026313A8 (pt) | 2011-04-12 | 2012-04-12 | composições e métodos para prevenir ou tratar doenças, condições ou processos caracterizados por proliferação anormal de fibroblastos e depósito de matriz extracelular |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US9642888B2 (enExample) |
| EP (1) | EP2696888B1 (enExample) |
| JP (1) | JP6031510B2 (enExample) |
| KR (1) | KR101862291B1 (enExample) |
| CN (3) | CN104302310A (enExample) |
| AU (1) | AU2012242768B2 (enExample) |
| BR (1) | BR112013026313A8 (enExample) |
| CA (2) | CA3042808A1 (enExample) |
| DK (1) | DK2696888T3 (enExample) |
| ES (1) | ES2711670T3 (enExample) |
| HK (1) | HK1255005A1 (enExample) |
| MX (1) | MX359516B (enExample) |
| RU (1) | RU2620066C2 (enExample) |
| SG (2) | SG10201604560TA (enExample) |
| WO (1) | WO2012142320A2 (enExample) |
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| DK1976828T3 (en) | 2005-12-29 | 2017-03-06 | Celtaxsys Inc | DIAMINE DERIVATIVES AS INhibitors of Leukotriene A4 HYDROLASE |
| EP2606903B1 (en) | 2007-01-10 | 2016-09-14 | Purdue Research Foundation | Polypeptide inhibitors of HSP27 kinase and uses therefor |
| ES2547229T3 (es) | 2007-08-07 | 2015-10-02 | Purdue Research Foundation | Inhibidores de cinasa y usos de los mismos |
| CN102316731B (zh) * | 2008-12-10 | 2016-06-01 | 普渡研究基金会 | 基于细胞渗透性肽的激酶抑制剂 |
| US9890195B2 (en) * | 2009-07-27 | 2018-02-13 | Purdue Research Foundation | MK2 inhibitor compositions and methods to enhance neurite outgrowth, neuroprotection, and nerve regeneration |
| US20110288036A1 (en) * | 2010-05-24 | 2011-11-24 | Cynthia Lander | Methods for Treating or Preventing Vascular Graft Failure |
| US9890200B2 (en) * | 2011-04-12 | 2018-02-13 | Moerae Matrix, Inc. | Compositions and methods for preventing or treating diseases, conditions, or processes characterized by aberrant fibroblast proliferation and extracellular matrix deposition |
| JP6031510B2 (ja) | 2011-04-12 | 2016-11-24 | モイライ マトリックス インコーポレイテッド | 異常な線維芽細胞増殖及び細胞外マトリックスの沈着を特徴とする疾患、症状又はプロセスを予防又は治療する組成物及び方法 |
| WO2014067986A1 (en) * | 2012-10-31 | 2014-05-08 | Galecto Biotech Ab | Galactoside inhibitor of galectin-3 and its use for treating pulmonary fibrosis |
| FR2976587B1 (fr) * | 2011-06-20 | 2015-04-03 | Basf Beauty Care Solutions F | Methode de dosage in vitro par technique immunologique |
| US9452218B2 (en) | 2012-03-09 | 2016-09-27 | Purdue Research Foundation | Compositions and methods for delivery of kinase inhibiting peptides |
| US9757529B2 (en) | 2012-12-20 | 2017-09-12 | Otitopic Inc. | Dry powder inhaler and methods of use |
| US9757395B2 (en) | 2012-12-20 | 2017-09-12 | Otitopic Inc. | Dry powder inhaler and methods of use |
| JP6527851B2 (ja) | 2013-03-12 | 2019-06-05 | セルタクシス,インコーポレイテッド | ロイコトリエンa4加水分解酵素を阻害する方法 |
| MX2015011677A (es) | 2013-03-14 | 2016-07-08 | Celtaxsys Inc | Inhibidores de leucotrieno a4 hidrolasa. |
| JP2016518388A (ja) | 2013-04-30 | 2016-06-23 | オティトピック インク. | 乾燥粉末配合および使用方法 |
| RU2016140332A (ru) * | 2014-03-14 | 2018-04-16 | Мори Матрикс, Инк. | Композиции и способы предотвращения или лечения хронической дисфункции аллотрансплантата легкого (хдал) и идиопатического фиброза легких (ифл) |
| US10336788B2 (en) * | 2014-04-17 | 2019-07-02 | Moerae Matrix, Inc. | Inhibition of cardiac fibrosis in myocardial infarction |
| KR20170083063A (ko) * | 2014-11-17 | 2017-07-17 | 모레 매트릭스 인코포레이티드 | 이상 섬유모세포 증식 및 세포외 기질 침착을 특징으로 하는 질병, 질환, 또는 과정의 예방 또는 치료용 조성물 및 방법 |
| MX2017008994A (es) * | 2015-01-08 | 2018-09-18 | Moerae Matrix Inc | Formulacion de peptidos inhibidores mk2. |
| RU2017135072A (ru) * | 2015-03-12 | 2019-04-10 | Мори Матрикс, Инк. | Применение пептидсодержащих композиций ингибитора mk2 для лечения немелкоклеточного рака легкого |
| US10786456B2 (en) | 2017-09-22 | 2020-09-29 | Otitopic Inc. | Inhaled aspirin and magnesium to treat inflammation |
| KR102507987B1 (ko) | 2017-09-22 | 2023-03-21 | 벡추라 인코포레이티드 | 스테아르산마그네슘을 갖는 건조 분말 조성물 |
| CN107987128B (zh) * | 2017-11-17 | 2019-06-11 | 广东医科大学 | 一种功能多肽及其在制备防治肺纤维化药物中的应用 |
| AU2019271285B2 (en) | 2018-05-17 | 2024-10-03 | Actuate Therapeutics, Inc. | Treatment of idiopathic pulmonary fibrosis with glycogen synthase kinase 3 form beta inhibitors |
| AU2019278935B2 (en) | 2018-05-31 | 2025-02-13 | Celltaxis, Llc | Method of reducing pulmonary exacerbations in respiratory disease patients |
| CN110108883A (zh) * | 2018-10-27 | 2019-08-09 | 广州呼吸健康研究院 | 用于筛选与靶治疗ards患者的msc精准医学的标志物组合 |
| CN109406795A (zh) * | 2018-11-20 | 2019-03-01 | 昆明医科大学 | 一种轻型脑外伤的血清分子诊断标记物及应用 |
| WO2021040673A1 (en) * | 2019-08-26 | 2021-03-04 | Alain Martin | Methods for the treatment of chronic hypoxemia and inhibiting lung fibrosis in patients with pulmonary fibrosis with and without copd |
| USD958124S1 (en) | 2019-12-16 | 2022-07-19 | Samsung Electronics Co., Ltd. | Television receiver |
| USD978094S1 (en) | 2019-12-27 | 2023-02-14 | Samsung Electronics Co., Ltd. | Television receiver |
| WO2021146662A1 (en) * | 2020-01-17 | 2021-07-22 | Muhammed Majeed | Therapeutic compositions and methods for pulmonary fibrosis |
| CN112386682B (zh) * | 2020-02-12 | 2022-12-06 | 王斌 | 纤连蛋白在制备治疗新型冠状病毒肺炎药物中的应用 |
| WO2021202031A1 (en) * | 2020-03-30 | 2021-10-07 | Figene, Llc | Peptides and adjuvants for augmentation of fibroblast therapy for coronavirus |
| WO2021202032A1 (en) * | 2020-04-01 | 2021-10-07 | Figene, Llc | Fibroblast mediated expansion and augmentation of immune regulatory cells for treatment of acute respiratory distress syndrome (ards) |
| US11505584B2 (en) * | 2020-04-21 | 2022-11-22 | Remodeless Cv Ltd | Therapy for reducing brain damage |
| USD989726S1 (en) | 2020-12-03 | 2023-06-20 | Samsung Electronics Co., Ltd. | Television receiver |
| KR20230117161A (ko) * | 2020-12-03 | 2023-08-07 | 지앙수 헨그루이 파마슈티컬스 컴퍼니 리미티드 | 항-결합 조직 성장 인자 항체를 포함하는 약학 조성물 |
| USD989017S1 (en) | 2020-12-03 | 2023-06-13 | Samsung Electronics Co., Ltd. | Television receiver |
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| CN113440431A (zh) * | 2021-08-02 | 2021-09-28 | 山西锦波生物医药股份有限公司 | 重组ⅲ型人源化胶原蛋白在头皮护理中的用途及包含其的头皮护理产品 |
| CN116262112A (zh) * | 2021-12-14 | 2023-06-16 | 南京安吉生物科技有限公司 | 一种雾化吸入用融合多肽制剂及其制备方法和应用 |
| JP2025503581A (ja) | 2022-01-14 | 2025-02-04 | 上▲海▼翰森生物医▲薬▼科技有限公司 | ピリジン含有多環系誘導体、その製造方法及び応用 |
| CN114522221B (zh) * | 2022-02-28 | 2024-04-19 | 中国人民解放军陆军特色医学中心 | 分泌蛋白ctgf在用于制备治疗急性肺损伤药物中的应用 |
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| CN116421704A (zh) * | 2023-02-20 | 2023-07-14 | 成都佩德生物医药有限公司 | 多肽pd-dp-005在制备治疗肺部疾病药物中的应用及其药物 |
| CN116789751B (zh) * | 2023-08-22 | 2023-11-17 | 中国农业大学 | 预防和/或治疗纤维化疾病的多肽及其应用 |
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| US20110288036A1 (en) * | 2010-05-24 | 2011-11-24 | Cynthia Lander | Methods for Treating or Preventing Vascular Graft Failure |
| JP6031510B2 (ja) | 2011-04-12 | 2016-11-24 | モイライ マトリックス インコーポレイテッド | 異常な線維芽細胞増殖及び細胞外マトリックスの沈着を特徴とする疾患、症状又はプロセスを予防又は治療する組成物及び方法 |
-
2012
- 2012-04-12 JP JP2014505291A patent/JP6031510B2/ja not_active Expired - Fee Related
- 2012-04-12 CN CN201280027012.2A patent/CN104302310A/zh active Pending
- 2012-04-12 CA CA3042808A patent/CA3042808A1/en not_active Abandoned
- 2012-04-12 CN CN201711403446.9A patent/CN108014340A/zh active Pending
- 2012-04-12 DK DK12771584.5T patent/DK2696888T3/en active
- 2012-04-12 ES ES12771584T patent/ES2711670T3/es active Active
- 2012-04-12 AU AU2012242768A patent/AU2012242768B2/en not_active Ceased
- 2012-04-12 MX MX2013011771A patent/MX359516B/es active IP Right Grant
- 2012-04-12 CA CA2832910A patent/CA2832910C/en not_active Expired - Fee Related
- 2012-04-12 EP EP12771584.5A patent/EP2696888B1/en not_active Not-in-force
- 2012-04-12 WO PCT/US2012/033368 patent/WO2012142320A2/en not_active Ceased
- 2012-04-12 BR BR112013026313A patent/BR112013026313A8/pt not_active Application Discontinuation
- 2012-04-12 RU RU2013150249A patent/RU2620066C2/ru not_active IP Right Cessation
- 2012-04-12 US US13/445,759 patent/US9642888B2/en not_active Expired - Fee Related
- 2012-04-12 SG SG10201604560TA patent/SG10201604560TA/en unknown
- 2012-04-12 KR KR1020137029996A patent/KR101862291B1/ko not_active Expired - Fee Related
- 2012-04-12 SG SG2013075031A patent/SG194135A1/en unknown
- 2012-04-12 CN CN201910892185.4A patent/CN111110850A/zh active Pending
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2017
- 2017-04-04 US US15/478,950 patent/US20190022169A1/en not_active Abandoned
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2018
- 2018-11-06 HK HK18114121.3A patent/HK1255005A1/zh unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR20140063517A (ko) | 2014-05-27 |
| WO2012142320A3 (en) | 2015-06-11 |
| CN108014340A (zh) | 2018-05-11 |
| US20190022169A1 (en) | 2019-01-24 |
| US20120263680A1 (en) | 2012-10-18 |
| MX359516B (es) | 2018-10-01 |
| AU2012242768B2 (en) | 2017-10-12 |
| DK2696888T3 (en) | 2019-03-25 |
| CA3042808A1 (en) | 2012-10-18 |
| CA2832910A1 (en) | 2012-10-18 |
| NZ616672A (en) | 2016-04-29 |
| US9642888B2 (en) | 2017-05-09 |
| KR101862291B1 (ko) | 2018-05-29 |
| RU2013150249A (ru) | 2015-05-20 |
| JP6031510B2 (ja) | 2016-11-24 |
| BR112013026313A2 (pt) | 2016-12-27 |
| ES2711670T3 (es) | 2019-05-06 |
| CN111110850A (zh) | 2020-05-08 |
| EP2696888A2 (en) | 2014-02-19 |
| JP2014533235A (ja) | 2014-12-11 |
| HK1255005A1 (zh) | 2019-08-02 |
| EP2696888A4 (en) | 2016-04-20 |
| SG194135A1 (en) | 2013-11-29 |
| AU2012242768A1 (en) | 2013-10-24 |
| EP2696888B1 (en) | 2018-12-05 |
| CA2832910C (en) | 2019-07-02 |
| WO2012142320A2 (en) | 2012-10-18 |
| SG10201604560TA (en) | 2016-07-28 |
| CN104302310A (zh) | 2015-01-21 |
| MX2013011771A (es) | 2014-07-30 |
| RU2620066C2 (ru) | 2017-05-22 |
| WO2012142320A8 (en) | 2014-02-20 |
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