CA2829045A1 - Compounds and methods for treatment of hypertension - Google Patents
Compounds and methods for treatment of hypertension Download PDFInfo
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- CA2829045A1 CA2829045A1 CA 2829045 CA2829045A CA2829045A1 CA 2829045 A1 CA2829045 A1 CA 2829045A1 CA 2829045 CA2829045 CA 2829045 CA 2829045 A CA2829045 A CA 2829045A CA 2829045 A1 CA2829045 A1 CA 2829045A1
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Classifications
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- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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- C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
- C07D455/03—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
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Landscapes
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- Nitrogen Condensed Heterocyclic Rings (AREA)
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| PCT/US2012/025755 WO2012112966A1 (en) | 2011-02-18 | 2012-02-17 | Compounds and methods for treatment of hypertension |
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| US6302875B1 (en) | 1996-10-11 | 2001-10-16 | Transvascular, Inc. | Catheters and related devices for forming passageways between blood vessels or other anatomical structures |
| US7617005B2 (en) | 2002-04-08 | 2009-11-10 | Ardian, Inc. | Methods and apparatus for thermally-induced renal neuromodulation |
| US9636174B2 (en) | 2002-04-08 | 2017-05-02 | Medtronic Ardian Luxembourg S.A.R.L. | Methods for therapeutic renal neuromodulation |
| US20070135875A1 (en) | 2002-04-08 | 2007-06-14 | Ardian, Inc. | Methods and apparatus for thermally-induced renal neuromodulation |
| US20080213331A1 (en) | 2002-04-08 | 2008-09-04 | Ardian, Inc. | Methods and devices for renal nerve blocking |
| US8150519B2 (en) | 2002-04-08 | 2012-04-03 | Ardian, Inc. | Methods and apparatus for bilateral renal neuromodulation |
| US20070129761A1 (en) | 2002-04-08 | 2007-06-07 | Ardian, Inc. | Methods for treating heart arrhythmia |
| US7653438B2 (en) | 2002-04-08 | 2010-01-26 | Ardian, Inc. | Methods and apparatus for renal neuromodulation |
| JP5219518B2 (ja) | 2004-12-09 | 2013-06-26 | ザ ファウンドリー， エルエルシー | 大動脈弁修復 |
| RU2007139634A (ru) | 2007-10-25 | 2009-04-27 | Сергей Олегович Бачурин (RU) | Новые тиазол-, триазол- или оксадиазол-содержащие тетрациклические соединения |
| RU2544856C2 (ru) | 2008-01-25 | 2015-03-20 | Сергей Олегович Бачурин | НОВЫЕ ПРОИЗВОДНЫЕ 2,3,4,5-ТЕТРАГИДРО-1-ПИРИДО[4,3-b]ИНДОЛА И СПОСОБЫ ИХ ПРИМЕНЕНИЯ |
| US8338447B2 (en) | 2008-03-24 | 2012-12-25 | Medivation Technologies, Inc. | Pyrido[3,4-B]indoles and methods of use |
| CN102046625B (zh) | 2008-03-24 | 2015-04-08 | 梅迪维新技术公司 | 桥连杂环化合物及其使用方法 |
| EP2348847A4 (en) | 2008-10-31 | 2012-05-23 | Medivation Technologies Inc | AZEPINO [4, 5-B] INDOLE AND USE PROCESS |
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| US8741919B2 (en) * | 2009-04-29 | 2014-06-03 | Medivation Technologies, Inc. | Pyrido[4,3-B]indoles and methods of use |
| CA2760541A1 (en) | 2009-04-29 | 2010-11-04 | Medivation Technologies, Inc. | Pyrido[4,3-b] indoles and methods of use |
| BR112012006640A2 (pt) | 2009-09-23 | 2019-09-24 | Medivation Technologies Inc | composto, composição farmacêutica, método de tratamento de um distúrbio cognitivo, distúrbiopsocótico, distúrbio mediado por neurotransmissor ou um distúrbio neuronal e kit |
| CN102724875B (zh) | 2009-09-23 | 2015-05-27 | 梅迪维新技术公司 | 吡啶并[3,4-b]吲哚化合物及其使用方法 |
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| US8697700B2 (en) | 2010-12-21 | 2014-04-15 | Albany Molecular Research, Inc. | Piperazinone-substituted tetrahydro-carboline MCH-1 antagonists, methods of making, and uses thereof |
| WO2012112965A1 (en) | 2011-02-18 | 2012-08-23 | Medivation Technologies, Inc. | Compounds and methods of treating diabetes |
| WO2012112963A1 (en) | 2011-02-18 | 2012-08-23 | Medivation Technologies, Inc. | Compounds and methods for treatment of hypertension |
| WO2012112964A2 (en) | 2011-02-18 | 2012-08-23 | Medivation Technologies, Inc. | PYRIDO[4,3-b]INDOLE AND PYRIDO[3,4-b]INDOLE DERIVATIVES AND METHODS OF USE |
| JP2014505737A (ja) | 2011-02-18 | 2014-03-06 | メディベイション テクノロジーズ， インコーポレイテッド | 糖尿病を処置する化合物および方法 |
| WO2014031170A1 (en) | 2012-08-22 | 2014-02-27 | Medivation Technologies, Inc. | Pyrido[4,3-b]indole and pyrido[3,4-b]indole derivatives and methods of use |
| WO2014031165A1 (en) | 2012-08-22 | 2014-02-27 | Medivation Technologies, Inc. | Compounds and methods of treating diabetes |
| AU2012388221B2 (en) | 2012-08-24 | 2017-08-31 | Board Of Regents Of The University Of Texas System | Pro-neurogenic compounds |
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2012
- 2012-02-17 JP JP2013554664A patent/JP2014505737A/ja active Pending
- 2012-02-17 CN CN201280019171.8A patent/CN103476416B/zh not_active Expired - Fee Related
- 2012-02-17 WO PCT/US2012/025749 patent/WO2012154261A1/en not_active Ceased
- 2012-02-17 JP JP2013554665A patent/JP2014505738A/ja active Pending
- 2012-02-17 WO PCT/US2012/025755 patent/WO2012112966A1/en not_active Ceased
- 2012-02-17 IN IN1699MUN2013 patent/IN2013MN01699A/en unknown
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- 2012-02-17 CA CA 2829045 patent/CA2829045A1/en not_active Abandoned
- 2012-02-17 US US13/400,031 patent/US8791132B2/en not_active Expired - Fee Related
- 2012-02-17 EP EP20120782062 patent/EP2675459A4/en not_active Withdrawn
- 2012-02-17 CA CA 2827642 patent/CA2827642A1/en not_active Abandoned
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- 2012-02-17 US US13/400,032 patent/US8815843B2/en not_active Expired - Fee Related
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- 2012-02-17 CN CN2012800192227A patent/CN103476417A/zh active Pending
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2013
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| EP2675459A1 (en) | 2013-12-25 |
| CN103476416A (zh) | 2013-12-25 |
| US9527854B2 (en) | 2016-12-27 |
| US20140088086A1 (en) | 2014-03-27 |
| AU2012219251B2 (en) | 2016-05-12 |
| US8815843B2 (en) | 2014-08-26 |
| US8791132B2 (en) | 2014-07-29 |
| US9550782B2 (en) | 2017-01-24 |
| WO2012154261A1 (en) | 2012-11-15 |
| EP2675458A4 (en) | 2014-08-06 |
| BR112013021125A2 (pt) | 2019-09-24 |
| BR112013021126A2 (pt) | 2019-09-24 |
| AU2012254158A1 (en) | 2013-05-02 |
| JP2014505737A (ja) | 2014-03-06 |
| CN103476417A (zh) | 2013-12-25 |
| EP2675458A1 (en) | 2013-12-25 |
| IN2013MN01699A (enExample) | 2015-06-12 |
| WO2012112966A1 (en) | 2012-08-23 |
| EP2675459A4 (en) | 2014-08-06 |
| AU2012219251A1 (en) | 2013-05-02 |
| US20130190294A1 (en) | 2013-07-25 |
| AU2012254158B2 (en) | 2016-02-04 |
| CA2827642A1 (en) | 2012-11-15 |
| US20150266884A1 (en) | 2015-09-24 |
| US9006263B2 (en) | 2015-04-14 |
| US20130053366A1 (en) | 2013-02-28 |
| US20130053367A1 (en) | 2013-02-28 |
| CN103476416B (zh) | 2016-09-21 |
| JP2014505738A (ja) | 2014-03-06 |
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