CA2810473C - Data independent acquisition of product ion spectra and reference spectra library matching - Google Patents
Data independent acquisition of product ion spectra and reference spectra library matching Download PDFInfo
- Publication number
- CA2810473C CA2810473C CA2810473A CA2810473A CA2810473C CA 2810473 C CA2810473 C CA 2810473C CA 2810473 A CA2810473 A CA 2810473A CA 2810473 A CA2810473 A CA 2810473A CA 2810473 C CA2810473 C CA 2810473C
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- Prior art keywords
- product ion
- sample
- compounds
- ion spectra
- spectra
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Classifications
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- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/0027—Methods for using particle spectrometers
- H01J49/0036—Step by step routines describing the handling of the data generated during a measurement
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/62—Detectors specially adapted therefor
- G01N30/72—Mass spectrometers
- G01N30/7233—Mass spectrometers interfaced to liquid or supercritical fluid chromatograph
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
- G16C20/00—Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
- G16C20/90—Programming languages; Computing architectures; Database systems; Data warehousing
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/0027—Methods for using particle spectrometers
- H01J49/0031—Step by step routines describing the use of the apparatus
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/004—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/004—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
- H01J49/0045—Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn characterised by the fragmentation or other specific reaction
-
- H—ELECTRICITY
- H01—ELECTRIC ELEMENTS
- H01J—ELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
- H01J49/00—Particle spectrometers or separator tubes
- H01J49/26—Mass spectrometers or separator tubes
- H01J49/34—Dynamic spectrometers
- H01J49/42—Stability-of-path spectrometers, e.g. monopole, quadrupole, multipole, farvitrons
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B40/00—ICT specially adapted for biostatistics; ICT specially adapted for bioinformatics-related machine learning or data mining, e.g. knowledge discovery or pattern finding
- G16B40/10—Signal processing, e.g. from mass spectrometry [MS] or from PCR
-
- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16C—COMPUTATIONAL CHEMISTRY; CHEMOINFORMATICS; COMPUTATIONAL MATERIALS SCIENCE
- G16C20/00—Chemoinformatics, i.e. ICT specially adapted for the handling of physicochemical or structural data of chemical particles, elements, compounds or mixtures
- G16C20/20—Identification of molecular entities, parts thereof or of chemical compositions
Landscapes
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Computing Systems (AREA)
- Theoretical Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Computational Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Databases & Information Systems (AREA)
- Software Systems (AREA)
- Physics & Mathematics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
- Electron Tubes For Measurement (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US38313710P | 2010-09-15 | 2010-09-15 | |
| EP10009595.9 | 2010-09-15 | ||
| EP10009595 | 2010-09-15 | ||
| US61/383,137 | 2010-09-15 | ||
| PCT/IB2011/002139 WO2012035412A2 (en) | 2010-09-15 | 2011-09-14 | Data independent acquisition of production spectra and reference spectra library matching |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2810473A1 CA2810473A1 (en) | 2012-03-22 |
| CA2810473C true CA2810473C (en) | 2018-06-26 |
Family
ID=44906224
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2810473A Active CA2810473C (en) | 2010-09-15 | 2011-09-14 | Data independent acquisition of product ion spectra and reference spectra library matching |
Country Status (6)
| Country | Link |
|---|---|
| US (9) | US8809770B2 (cg-RX-API-DMAC10.html) |
| EP (1) | EP2617052B1 (cg-RX-API-DMAC10.html) |
| JP (6) | JP5875587B2 (cg-RX-API-DMAC10.html) |
| CN (2) | CN103109345B (cg-RX-API-DMAC10.html) |
| CA (1) | CA2810473C (cg-RX-API-DMAC10.html) |
| WO (1) | WO2012035412A2 (cg-RX-API-DMAC10.html) |
Families Citing this family (108)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3533908B1 (en) | 2010-07-02 | 2026-07-01 | The Procter & Gamble Company | NONWOVEN FABRIC COMPRISING ONE OR MORE ACTIVE AGENTS |
| JP5859526B2 (ja) | 2010-07-02 | 2016-02-10 | ザ プロクター アンド ギャンブルカンパニー | 活性剤不織布ウェブを含むフィラメント及びその製造方法 |
| MX382405B (es) | 2010-07-02 | 2025-03-13 | Procter & Gamble | Método para suministrar un agente activo. |
| WO2012035412A2 (en) * | 2010-09-15 | 2012-03-22 | Dh Technologies Development Pte. Ltd. | Data independent acquisition of production spectra and reference spectra library matching |
| CN106252192B (zh) | 2010-11-08 | 2018-04-03 | Dh科技发展私人贸易有限公司 | 用于通过质谱分析快速筛选样本的系统及方法 |
| EP2715770B1 (en) * | 2011-06-03 | 2021-11-24 | DH Technologies Development Pte. Ltd. | Use of variable xic widths of tof-msms data for the determination of background interference in srm assays |
| US9435778B2 (en) | 2011-09-28 | 2016-09-06 | BiognoSYS AG | Methods and systems for experimental set-up and data analysis in targeted proteomics applications |
| US9048072B2 (en) * | 2012-03-12 | 2015-06-02 | Micromass Uk Limited | Method of mass spectrometry and a mass spectrometer |
| CN104160473B (zh) * | 2012-04-02 | 2017-03-15 | Dh科技发展私人贸易有限公司 | 使用离子阱跨越质量范围进行连续窗口化获取的系统及方法 |
| WO2013171554A1 (en) | 2012-05-18 | 2013-11-21 | Dh Technologies Development Pte. Ltd. | Systems and methods for using interleaving window widths in tandem mass spectrometry |
| US9779923B2 (en) | 2013-03-14 | 2017-10-03 | Leco Corporation | Method and system for tandem mass spectrometry |
| EP3004871B1 (en) * | 2013-06-05 | 2019-05-15 | DH Technologies Development PTE. Ltd. | Swathtm data-independent acquisition technology for the detection of host cell protein contaminants in biotherapeutics protein products |
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| US10930481B2 (en) * | 2013-08-13 | 2021-02-23 | Purdue Research Foundation | Sample quantitation with a miniature mass spectrometer |
| CA2925853A1 (en) * | 2013-10-16 | 2015-04-23 | Dh Technologies Development Pte. Ltd. | Systems and methods for identifying precursor ions from product ions using arbitrary transmission windowing |
| JP6581976B2 (ja) * | 2013-10-16 | 2019-09-25 | ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド | 恣意的四重極伝送窓生成のためのシステムおよび方法 |
| US9583321B2 (en) * | 2013-12-23 | 2017-02-28 | Thermo Finnigan Llc | Method for mass spectrometer with enhanced sensitivity to product ions |
| CN105917220B (zh) * | 2014-01-16 | 2019-05-28 | 株式会社岛津制作所 | 质谱分析装置 |
| JP6585087B2 (ja) * | 2014-06-02 | 2019-10-02 | ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド | 質量スペクトルライブラリを正確な質量スペクトルライブラリに転換する方法 |
| WO2016002047A1 (ja) * | 2014-07-03 | 2016-01-07 | 株式会社島津製作所 | 質量分析データ処理装置 |
| WO2016055888A1 (en) * | 2014-10-08 | 2016-04-14 | Dh Technologies Development Pte. Ltd. | Improving ida spectral output for database searches |
| EP3218703B1 (en) * | 2014-11-13 | 2019-06-26 | DH Technologies Development PTE. Ltd. | Determining the identity of modified compounds |
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| WO2016145331A1 (en) * | 2015-03-12 | 2016-09-15 | Thermo Finnigan Llc | Methods for data-dependent mass spectrometry of mixed biomolecular analytes |
| US10591448B2 (en) * | 2015-04-14 | 2020-03-17 | Waters Technologies Corporation | Structural elucidation of isotopically labeled analytes |
| CN107533031B (zh) * | 2015-05-13 | 2020-09-29 | Dh科技发展私人贸易有限公司 | 自上而下蛋白质鉴定方法 |
| US10573501B2 (en) * | 2015-05-29 | 2020-02-25 | Waters Technologies Corporation | Techniques for processing of mass spectral data |
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| US11024492B2 (en) | 2015-07-07 | 2021-06-01 | Institute For Systems Biology | Method to obtain unbiased identification of interaction of test compounds with the proteome |
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| EP3335236B1 (en) * | 2015-08-13 | 2020-05-06 | DH Technologies Development PTE. Ltd. | Library search tolerant to isotopes |
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| US10204770B2 (en) | 2015-08-31 | 2019-02-12 | Dh Technologies Development Pte. Ltd. | Method to improve MS/MS spectral quality from MRM triggered IDA |
| GB2544959B (en) * | 2015-09-17 | 2019-06-05 | Thermo Fisher Scient Bremen Gmbh | Mass spectrometer |
| US10890562B2 (en) * | 2015-10-07 | 2021-01-12 | Shimadzu Corporation | Tandem mass spectrometer |
| EP3193352A1 (en) | 2016-01-14 | 2017-07-19 | Thermo Finnigan LLC | Methods for mass spectrometric based characterization of biological molecules |
| US10340130B2 (en) | 2016-04-05 | 2019-07-02 | Thermo Finnigan Llc | Data independent acquisition with variable multiplexing degree |
| WO2018007921A1 (en) | 2016-07-06 | 2018-01-11 | Dh Technologies Development Pte. Ltd. | Results dependent analysis - iterative analysis of swath data |
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| CN108061776B (zh) * | 2016-11-08 | 2020-08-28 | 中国科学院大连化学物理研究所 | 一种用于液相色谱-质谱的代谢组学数据峰匹配方法 |
| US9911585B1 (en) | 2016-12-21 | 2018-03-06 | Thermo Finnigan Llc | Data-independent mass spectral data acquisition including data-dependent precursor-ion surveys |
| CN110167639B (zh) | 2017-01-27 | 2022-10-14 | 宝洁公司 | 呈包含泡腾型附聚颗粒的可溶性固体结构形式的组合物 |
| CN110191700A (zh) | 2017-01-27 | 2019-08-30 | 宝洁公司 | 可溶性固体结构形式的组合物 |
| GB2559395B (en) * | 2017-02-03 | 2020-07-01 | Thermo Fisher Scient Bremen Gmbh | High resolution MS1 based quantification |
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| US9897581B1 (en) | 2017-04-26 | 2018-02-20 | Thermo Finnigan Llc | Variable data-dependent acquisition and dynamic exclusion method for mass spectrometry |
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| EP3958290B1 (en) | 2017-06-02 | 2024-09-25 | Thermo Fisher Scientific (Bremen) GmbH | Hybrid mass spectrometer |
| CN111164422B (zh) * | 2017-08-07 | 2023-05-02 | 新加坡科技研究局 | 从液相色谱-质谱(lc-ms)数据中快速分析和鉴定脂质 |
| WO2019043650A1 (en) | 2017-08-31 | 2019-03-07 | Dh Technologies Development Pte. Ltd. | CALCULATION OF DYNAMIC BALANCING TIME TO IMPROVE DYNAMIC MS / MS RANGE |
| JP2020535599A (ja) * | 2017-09-29 | 2020-12-03 | ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド | 同位体選択的ｍｓ／ｍｓを用いたｍｒｍピーク純度の査定 |
| CN109830426B (zh) | 2017-11-23 | 2021-04-02 | 株式会社岛津制作所 | 质谱数据采集方法 |
| CN109828068B (zh) * | 2017-11-23 | 2021-12-28 | 株式会社岛津制作所 | 质谱数据采集及分析方法 |
| WO2019142068A1 (en) * | 2018-01-17 | 2019-07-25 | Dh Technologies Development Pte. Ltd. | Dm-swath acquisition to improve msms confidence |
| WO2019161382A1 (en) * | 2018-02-19 | 2019-08-22 | Cerno Bioscience Llc | Reliable and automatic mass spectral analysis |
| GB201810273D0 (en) * | 2018-06-22 | 2018-08-08 | Thermo Fisher Scient Bremen Gmbh | Structural analysis of ionised molecules |
| US11666514B2 (en) | 2018-09-21 | 2023-06-06 | The Procter & Gamble Company | Fibrous structures containing polymer matrix particles with perfume ingredients |
| WO2020110584A1 (ja) * | 2018-11-28 | 2020-06-04 | 株式会社島津製作所 | アゾ化合物の分析方法 |
| US12174162B2 (en) * | 2018-11-29 | 2024-12-24 | Shimadzu Corporation | Hazardous substance analyzing system |
| EP3660504B1 (en) * | 2018-11-30 | 2025-01-01 | Thermo Fisher Scientific (Bremen) GmbH | Systems and methods for determining mass of an ion species |
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| GB2590601B (en) * | 2019-11-13 | 2024-01-31 | Thermo Fisher Scient Bremen Gmbh | Method of mass spectrometry |
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| US11721538B2 (en) | 2020-11-17 | 2023-08-08 | Thermo Finnigan Llc | Feeding real time search results of chimeric MS2 spectra into the dynamic exclusion list |
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| EP4047371A1 (en) * | 2021-02-18 | 2022-08-24 | Thermo Fisher Scientific (Bremen) GmbH | Method and apparatus for analysing samples of biomolecules using mass spectrometry with data-independent acquisition |
| WO2022184832A2 (en) | 2021-03-03 | 2022-09-09 | Immatics Biotechnologies Gmbh | Method for the absolute quantification of mhc molecules |
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| CN117581330A (zh) | 2021-06-09 | 2024-02-20 | Dh科技发展私人贸易有限公司 | 扫描swath中增强的q1质量分离 |
| US20250125133A1 (en) | 2021-07-23 | 2025-04-17 | Dh Technologies Development Pte. Ltd. | Preventing Errors in Processing and Interpreting Mass Spectrometry Results |
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| EP4395730A1 (en) | 2021-08-30 | 2024-07-10 | The Procter & Gamble Company | Dissolvable solid structure comprising first and second polymeric structurants |
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| US12009194B2 (en) * | 2021-12-14 | 2024-06-11 | Thermo Finnigan Llc | Mass spectrometry data-independent analysis methods with improved efficiency |
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| EP4473537A1 (en) | 2022-02-04 | 2024-12-11 | DH Technologies Development Pte. Ltd. | Compound identification using a mass spectrum |
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| WO2023199138A1 (en) | 2022-04-12 | 2023-10-19 | Dh Technologies Development Pte. Ltd. | Scoring of whole protein msms spectra based on a bond relevance score |
| WO2023203620A1 (ja) | 2022-04-18 | 2023-10-26 | 株式会社島津製作所 | 質量分析装置 |
| GB2621394B (en) | 2022-08-12 | 2024-12-04 | Thermo Fisher Scient Bremen Gmbh | Methods and Mass Spectrometry Systems for Acquiring Mass Spectral Data |
| GB2621395B (en) | 2022-08-12 | 2025-02-05 | Thermo Fisher Scient Bremen Gmbh | Methods and mass spectrometry systems for acquiring mass spectral data |
| GB2621393B (en) | 2022-08-12 | 2024-12-25 | Thermo Fisher Scient Bremen Gmbh | Methods and mass spectrometry systems for acquiring mass spectral data |
| US20260079140A1 (en) | 2022-10-06 | 2026-03-19 | Dh Technologies Development Pte. Ltd. | Reducing Data Complexity for Subsequent RT Alignment |
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| US20260078445A1 (en) | 2022-12-07 | 2026-03-19 | Dh Technologies Development Pte. Ltd. | De Novo Sequencing of DNA |
| EP4649518A1 (en) | 2023-01-09 | 2025-11-19 | DH Technologies Development Pte. Ltd. | Sequencing of morpholino oligomers using electron capture dissociation |
| FR3149423B1 (fr) | 2023-06-05 | 2025-05-30 | Synchrotron Soleil | Procédé de reconstruction d’un spectre de masse |
| GB2631473B (en) * | 2023-06-30 | 2026-01-28 | Thermo Fisher Scient Bremen Gmbh | Quantifying a substance present in a sample |
| GB2700079B (en) * | 2023-07-21 | 2026-03-25 | Thermo Fisher Scient Bremen Gmbh | Compound assembly |
| WO2026159683A1 (en) * | 2025-01-24 | 2026-07-30 | Dh Technologies Development Pte. Ltd. | Quantification of chemical species using data independent acquisition |
Family Cites Families (69)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3699333A (en) * | 1968-10-23 | 1972-10-17 | Franklin Gno Corp | Apparatus and methods for separating, concentrating, detecting, and measuring trace gases |
| US3626178A (en) * | 1970-02-20 | 1971-12-07 | Franklin Gno Corp | Gas or liquid chromatograph with detector employing ion-molecule reactions and ion drift |
| US3812355A (en) * | 1971-12-09 | 1974-05-21 | Gno F Corp | Apparatus and methods for measuring ion mass as a function of mobility |
| US4023398A (en) * | 1975-03-03 | 1977-05-17 | John Barry French | Apparatus for analyzing trace components |
| DE3578980D1 (de) | 1984-11-07 | 1990-09-06 | Gen Electric | Silanderivate zur verbesserung der eigenschaften von polyphenylenoxid-polyamidzusammensetzungen. |
| US4818862A (en) * | 1987-10-21 | 1989-04-04 | Iowa State University Research Foundation, Inc. | Characterization of compounds by time-of-flight measurement utilizing random fast ions |
| US5179278A (en) * | 1991-08-23 | 1993-01-12 | Mds Health Group Limited | Multipole inlet system for ion traps |
| US5455417A (en) * | 1994-05-05 | 1995-10-03 | Sacristan; Emilio | Ion mobility method and device for gas analysis |
| US6573492B2 (en) * | 1999-12-27 | 2003-06-03 | Hitachi, Ltd. | Mass spectrometric analysis method and apparatus using the method |
| US6586727B2 (en) * | 2000-06-09 | 2003-07-01 | Micromass Limited | Methods and apparatus for mass spectrometry |
| CA2340150C (en) * | 2000-06-09 | 2005-11-22 | Micromass Limited | Methods and apparatus for mass spectrometry |
| IL154932A0 (en) * | 2000-10-11 | 2003-10-31 | Ciphergen Biosystems Inc | Apparatus and methods for affinity capture tandem mass spectrometry |
| US6524803B2 (en) * | 2000-12-19 | 2003-02-25 | Agilent Technologies, Inc. | Deconvolution method and apparatus for analyzing compounds |
| US20020127609A1 (en) * | 2001-02-23 | 2002-09-12 | Maxygen, Inc. | Screening for enzyme stereoselectivity utilizing mass spectrometry |
| DE10145904A1 (de) * | 2001-09-18 | 2003-04-10 | Bruker Daltonik Gmbh | Verfahren zur Aufklärung des Metabolismus |
| JP3990889B2 (ja) * | 2001-10-10 | 2007-10-17 | 株式会社日立ハイテクノロジーズ | 質量分析装置およびこれを用いる計測システム |
| WO2003087770A2 (en) | 2002-04-12 | 2003-10-23 | Northeastern University | Matched filtration with experimental noise determination for denoising, peak picking and quantitation in lc-ms |
| WO2003098190A2 (en) * | 2002-05-20 | 2003-11-27 | Purdue Research Foundation | Protein identification from protein product ion spectra |
| US20040014143A1 (en) * | 2002-05-29 | 2004-01-22 | Haskins William E. | Method and apparatus for detecting and monitoring peptides, and peptides identified therewith |
| NZ520019A (en) * | 2002-07-05 | 2005-02-25 | Syft Technologies Ltd | A method of assaying the antioxidant activity of pure compounds, extracts and biological fluids using SIFT-MS technology |
| GB2390935A (en) * | 2002-07-16 | 2004-01-21 | Anatoli Nicolai Verentchikov | Time-nested mass analysis using a TOF-TOF tandem mass spectrometer |
| GB0305796D0 (en) * | 2002-07-24 | 2003-04-16 | Micromass Ltd | Method of mass spectrometry and a mass spectrometer |
| JP4160558B2 (ja) * | 2002-08-22 | 2008-10-01 | アプレラ コーポレイション | 結果主導型ストラテジーを利用して生体分子を特徴付けるための方法 |
| JP3534191B1 (ja) * | 2002-12-26 | 2004-06-07 | 日本電気株式会社 | 質量分析法を利用するペプチドｃ末端アミノ酸配列解析方法 |
| EP1586104A2 (en) * | 2003-01-24 | 2005-10-19 | Thermo Finnigan LLC | Controlling ion populations in a mass analyzer |
| GB2418775B (en) * | 2003-03-19 | 2008-10-15 | Thermo Finnigan Llc | Obtaining tandem mass spectrometry data for multiple parent ions in an ion population |
| US7459693B2 (en) * | 2003-04-04 | 2008-12-02 | Bruker Daltonics, Inc. | Ion guide for mass spectrometers |
| US9357755B2 (en) * | 2003-10-28 | 2016-06-07 | The University Of Wyoming | Production of human glycosylated proteins in silk worm |
| US7365309B2 (en) * | 2003-12-22 | 2008-04-29 | Micromass Uk Limited | Mass spectrometer |
| US20080206737A1 (en) * | 2004-05-19 | 2008-08-28 | Hunter Christie L | Expression quantification using mass spectrometry |
| US20070054345A1 (en) * | 2004-05-19 | 2007-03-08 | Hunter Christie L | Expression quantification using mass spectrometry |
| NZ534909A (en) * | 2004-08-26 | 2005-10-28 | Syft Technologies Ltd | A method of assaying the antioxidant activity of oils and lipids using SIFT-MS technology |
| JP4643206B2 (ja) * | 2004-09-03 | 2011-03-02 | 株式会社日立ハイテクノロジーズ | 質量分析装置 |
| CN100390537C (zh) * | 2004-11-12 | 2008-05-28 | 中国科学院计算技术研究所 | 用串联质谱中碎片离子的同位素峰预测离子分子式的方法 |
| JP2006322899A (ja) * | 2005-05-20 | 2006-11-30 | Hitachi Ltd | ガスモニタリング装置 |
| DE102005025499B4 (de) * | 2005-06-03 | 2007-09-27 | Bruker Daltonik Gmbh | Massenspektrometrische Gemischanalyse |
| WO2007022248A2 (en) * | 2005-08-16 | 2007-02-22 | Sloan Kettering Institute For Cancer Research | Methods of detection of cancer using peptide profiles |
| GB2432712B (en) * | 2005-11-23 | 2007-12-27 | Micromass Ltd | Mass spectrometer |
| JP4782579B2 (ja) * | 2006-02-15 | 2011-09-28 | 株式会社日立ハイテクノロジーズ | タンデム型質量分析システム及び方法 |
| US20080173807A1 (en) * | 2006-04-11 | 2008-07-24 | Oh-Kyu Yoon | Fragmentation modulation mass spectrometry |
| EP2013224A2 (en) * | 2006-04-27 | 2009-01-14 | Syddansk Universitet | Methods for isolation and analysis of sialylated and phosphorylated peptides |
| GB0609253D0 (en) * | 2006-05-10 | 2006-06-21 | Micromass Ltd | Mass spectrometer |
| JP4577266B2 (ja) * | 2006-05-16 | 2010-11-10 | 株式会社島津製作所 | クロマトグラフ質量分析装置 |
| US7956320B2 (en) * | 2006-05-18 | 2011-06-07 | Shimadzu Corporation | Data processor for mass spectrometer |
| EP2021789A4 (en) * | 2006-05-26 | 2010-10-20 | Waters Technologies Corp | DEVICE AND METHOD FOR IMPROVING MASS SPECTROSCOPY |
| JP5039330B2 (ja) * | 2006-06-30 | 2012-10-03 | 株式会社日立ハイテクノロジーズ | 質量分析システム |
| WO2008008919A2 (en) * | 2006-07-12 | 2008-01-17 | Applera Corporation | Methods and systems for sequence-based design of multiple reaction monitoring transitions and experiments |
| US7638762B2 (en) * | 2006-09-29 | 2009-12-29 | Agilent Technologies, Inc. | Systems and methods for decreasing settling times in MS/MS |
| GB0622689D0 (en) * | 2006-11-14 | 2006-12-27 | Thermo Electron Bremen Gmbh | Method of operating a multi-reflection ion trap |
| GB0704764D0 (en) | 2007-03-12 | 2007-04-18 | Electrophoretics Ltd | Isobarically labelled reagents and methods of their use |
| WO2008142579A2 (en) * | 2007-05-23 | 2008-11-27 | Williamson Nicholas A | Method of mass analysis of target molecules in complex mixtures |
| JP4905265B2 (ja) * | 2007-06-18 | 2012-03-28 | 株式会社島津製作所 | クロマトグラフ質量分析装置用データ処理装置 |
| ES2374762T3 (es) * | 2007-10-10 | 2012-02-21 | Bg Medicine, Inc. | Procedimientos para detectar complicaciones cardiovasculares y cerebrovasculares adversas graves. |
| US8030612B2 (en) * | 2007-11-09 | 2011-10-04 | Dh Technologies Development Pte. Ltd. | High resolution excitation/isolation of ions in a low pressure linear ion trap |
| WO2009070871A1 (en) * | 2007-12-04 | 2009-06-11 | Mds Analytical Technologies, A Business Unit Of Mds Inc. Doing Business Through Its Sciex Division | Systems and methods for analyzing substances using a mass spectrometer |
| US7897405B2 (en) * | 2008-02-11 | 2011-03-01 | Thermo Finnigan Llc | Method for identifying the elution time of an analyte |
| CN102067273B (zh) * | 2008-03-05 | 2013-12-11 | 株式会社岛津制作所 | 质量分析装置 |
| WO2009114932A1 (en) * | 2008-03-20 | 2009-09-24 | Mds Analytical Technologies, A Business Unit Of Mds Inc., | Systems and methods for analyzing substances using a mass spectrometer |
| US8841423B2 (en) * | 2008-04-28 | 2014-09-23 | University Of Iowa Research Foundation | Monoclonal antibodies specific for oxidized calcium/calmodulin dependent protein kinase II |
| GB0811298D0 (en) * | 2008-06-19 | 2008-07-30 | Trillion Genomics Ltd | Characterising polypeptides |
| JP4973628B2 (ja) * | 2008-08-29 | 2012-07-11 | 株式会社島津製作所 | クロマトグラフ質量分析データ解析方法及び装置 |
| JP4941437B2 (ja) * | 2008-09-12 | 2012-05-30 | 株式会社島津製作所 | 四重極型質量分析装置 |
| WO2010080986A1 (en) * | 2009-01-09 | 2010-07-15 | Mds Analytical Technologies | Mass spectrometer |
| GB0900973D0 (en) * | 2009-01-21 | 2009-03-04 | Micromass Ltd | Method and apparatus for performing MS^N |
| WO2010089798A1 (ja) * | 2009-02-05 | 2010-08-12 | 株式会社島津製作所 | Ｍｓ／ｍｓ型質量分析装置 |
| US8395113B2 (en) * | 2009-05-08 | 2013-03-12 | Thermo Finnigan Llc | Methods and systems for matching product ions to precursor in tandem mass spectrometry |
| US20100301205A1 (en) * | 2009-05-27 | 2010-12-02 | Bruce Thomson | Linear ion trap for msms |
| EP2614517B1 (en) | 2010-09-08 | 2020-08-05 | DH Technologies Development Pte. Ltd. | Systems and methods for using variable mass selection window widths in tandem mass spectrometry |
| WO2012035412A2 (en) * | 2010-09-15 | 2012-03-22 | Dh Technologies Development Pte. Ltd. | Data independent acquisition of production spectra and reference spectra library matching |
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