CA2793527A1 - Use of naphthofuran derivatives in the treatment of cancer - Google Patents

Use of naphthofuran derivatives in the treatment of cancer Download PDF

Info

Publication number
CA2793527A1
CA2793527A1 CA2793527A CA2793527A CA2793527A1 CA 2793527 A1 CA2793527 A1 CA 2793527A1 CA 2793527 A CA2793527 A CA 2793527A CA 2793527 A CA2793527 A CA 2793527A CA 2793527 A1 CA2793527 A1 CA 2793527A1
Authority
CA
Canada
Prior art keywords
compound
polymorph
degrees
peak
cancer
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA2793527A
Other languages
English (en)
French (fr)
Inventor
Chiang Jia Li
David Leggett
Youzhi Li
Wei Li
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sumitomo Pharma Oncology Inc
Original Assignee
Boston Biomedical Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boston Biomedical Inc filed Critical Boston Biomedical Inc
Publication of CA2793527A1 publication Critical patent/CA2793527A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
CA2793527A 2010-03-19 2011-03-21 Use of naphthofuran derivatives in the treatment of cancer Abandoned CA2793527A1 (en)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US31589010P 2010-03-19 2010-03-19
US31588610P 2010-03-19 2010-03-19
US61/315,890 2010-03-19
US61/315,886 2010-03-19
US32581410P 2010-04-19 2010-04-19
US61/325,814 2010-04-19
PCT/US2011/029283 WO2011116399A1 (en) 2010-03-19 2011-03-21 Novel methods for targeting cancer stem cells

Publications (1)

Publication Number Publication Date
CA2793527A1 true CA2793527A1 (en) 2011-09-22

Family

ID=47678420

Family Applications (2)

Application Number Title Priority Date Filing Date
CA2793527A Abandoned CA2793527A1 (en) 2010-03-19 2011-03-21 Use of naphthofuran derivatives in the treatment of cancer
CA2946890A Abandoned CA2946890A1 (en) 2010-03-19 2011-03-21 Naphthofuran compounds and compositions for targeting cancer stem cells

Family Applications After (1)

Application Number Title Priority Date Filing Date
CA2946890A Abandoned CA2946890A1 (en) 2010-03-19 2011-03-21 Naphthofuran compounds and compositions for targeting cancer stem cells

Country Status (18)

Country Link
US (2) US9730909B2 (enExample)
EP (1) EP2547205B1 (enExample)
JP (1) JP2013522326A (enExample)
CN (1) CN103025159A (enExample)
AU (1) AU2011227023B2 (enExample)
BR (1) BR112012023660B8 (enExample)
CA (2) CA2793527A1 (enExample)
DK (1) DK2547205T3 (enExample)
ES (1) ES2987670T3 (enExample)
FI (1) FI2547205T3 (enExample)
HR (1) HRP20240658T1 (enExample)
LT (1) LT2547205T (enExample)
PL (1) PL2547205T3 (enExample)
RS (1) RS65536B1 (enExample)
RU (1) RU2591823C2 (enExample)
SI (1) SI2547205T1 (enExample)
SM (1) SMT202400193T1 (enExample)
WO (1) WO2011116399A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10377731B2 (en) 2007-09-10 2019-08-13 Boston Biomedical, Inc. Compositions and methods for cancer treatment

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CA2959951A1 (en) * 2010-03-19 2011-09-22 Boston Biomedical, Inc. Naphthofuran compounds and compositions for targeting cancer stem cells
KR20150139955A (ko) 2013-04-09 2015-12-14 보스톤 바이오메디칼, 인크. 암 치료에 사용하기 위한 2-아세틸나프토[2,3-b]푸란-4,9-디온
EP3102036A4 (en) 2014-02-07 2017-09-20 Boston Biomedical, Inc. 3-substituted carbonyl-naphtho[2,3-b]furane derivative or pharmaceutically acceptable salt thereof
AU2015272560B2 (en) * 2014-06-09 2019-02-14 Kyoto Pharmaceutical Industries, Ltd. Novel anticancer agent
TW201713327A (zh) 2015-04-17 2017-04-16 波士頓生醫公司 治療癌症之方法
JP2018511645A (ja) 2015-04-17 2018-04-26 ボストン バイオメディカル, インコーポレイテッド 癌を治療するための方法
BR112017026025A2 (pt) 2015-06-03 2018-08-14 Boston Biomedical Inc composições que compreendem um inibidor de stemness de câncer e um agente imunoterápico para uso no tratamento de câncer
JP6871919B2 (ja) 2015-06-16 2021-05-19 ナノファギックス エルエルシー 薬物送達及びイメージング化学コンジュゲート、製剤及びその使用方法
WO2017013270A1 (en) 2015-07-23 2017-01-26 Universite De Strasbourg Use of leptin signaling inhibitor for protecting kidneys from patients having ciliopathy
WO2017132049A1 (en) 2016-01-20 2017-08-03 Boston Biomedical, Inc. Methods for treating cancer
CA3029596A1 (en) 2016-06-28 2018-01-04 Boston Biomedical, Inc. Methods for treating cancer
WO2018098352A2 (en) 2016-11-22 2018-05-31 Jun Oishi Targeting kras induced immune checkpoint expression
US11299469B2 (en) 2016-11-29 2022-04-12 Sumitomo Dainippon Pharma Oncology, Inc. Naphthofuran derivatives, preparation, and methods of use thereof
US10646464B2 (en) 2017-05-17 2020-05-12 Boston Biomedical, Inc. Methods for treating cancer
US10926226B2 (en) * 2018-03-08 2021-02-23 ExxonMobil Research & Engineering Company Company Functionalized membranes and methods of production thereof
WO2020074010A1 (zh) 2018-10-12 2020-04-16 北京强新生物科技有限公司 治疗化疗难治性癌症的新联合用药方案
CN111825644B (zh) * 2019-04-18 2023-07-28 中国医学科学院药物研究所 2,3-二氢萘并[2,3-b]呋喃-4,9-二酮类化合物及其制备方法和用途
CN117350965A (zh) * 2023-10-07 2024-01-05 中国原子能科学研究院 对象内放射性微球的指标预估装置

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10377731B2 (en) 2007-09-10 2019-08-13 Boston Biomedical, Inc. Compositions and methods for cancer treatment

Also Published As

Publication number Publication date
PL2547205T3 (pl) 2024-07-08
EP2547205B1 (en) 2024-03-20
SI2547205T1 (sl) 2024-08-30
AU2011227023A1 (en) 2012-09-27
HRP20240658T1 (hr) 2024-08-16
US20130028944A1 (en) 2013-01-31
BR112012023660B8 (pt) 2021-05-25
CN103025159A (zh) 2013-04-03
BR112012023660A2 (pt) 2015-09-15
AU2011227023B2 (en) 2015-05-28
SMT202400193T1 (it) 2024-07-09
US9730909B2 (en) 2017-08-15
RU2591823C2 (ru) 2016-07-20
CA2946890A1 (en) 2011-09-22
DK2547205T3 (da) 2024-05-27
JP2013522326A (ja) 2013-06-13
LT2547205T (lt) 2024-06-10
BR112012023660B1 (pt) 2021-05-18
EP2547205A4 (en) 2013-08-14
EP2547205A1 (en) 2013-01-23
US20170319537A1 (en) 2017-11-09
FI2547205T3 (fi) 2024-05-27
RU2012144420A (ru) 2014-04-27
RS65536B1 (sr) 2024-06-28
ES2987670T3 (es) 2024-11-15
WO2011116399A1 (en) 2011-09-22

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Legal Events

Date Code Title Description
EEER Examination request

Effective date: 20150804

FZDE Discontinued

Effective date: 20170929