RU2591823C2 - Новые способы направленного воздействия на раковые стволовые клетки - Google Patents

Новые способы направленного воздействия на раковые стволовые клетки Download PDF

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RU2591823C2
RU2591823C2 RU2012144420/15A RU2012144420A RU2591823C2 RU 2591823 C2 RU2591823 C2 RU 2591823C2 RU 2012144420/15 A RU2012144420/15 A RU 2012144420/15A RU 2012144420 A RU2012144420 A RU 2012144420A RU 2591823 C2 RU2591823 C2 RU 2591823C2
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compound
polymorph
degrees
cancer
peak
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RU2012144420/15A
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Russian (ru)
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RU2012144420A (ru
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Чиан Цзя ЛИ
Дэвид ЛЕДЖЕТТ
Ючжи ЛИ
Вэй Ли
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Бостон Байомедикал, Инк.
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • A61K31/343Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide condensed with a carbocyclic ring, e.g. coumaran, bufuralol, befunolol, clobenfurol, amiodarone
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/27Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis

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  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Emergency Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
RU2012144420/15A 2010-03-19 2011-03-21 Новые способы направленного воздействия на раковые стволовые клетки RU2591823C2 (ru)

Applications Claiming Priority (7)

Application Number Priority Date Filing Date Title
US31588610P 2010-03-19 2010-03-19
US31589010P 2010-03-19 2010-03-19
US61/315,890 2010-03-19
US61/315,886 2010-03-19
US32581410P 2010-04-19 2010-04-19
US61/325,814 2010-04-19
PCT/US2011/029283 WO2011116399A1 (en) 2010-03-19 2011-03-21 Novel methods for targeting cancer stem cells

Related Child Applications (1)

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RU2016123004A Division RU2657750C1 (ru) 2010-03-19 2011-03-21 Новые способы направленного воздействия на раковые стволовые клетки

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RU2012144420A RU2012144420A (ru) 2014-04-27
RU2591823C2 true RU2591823C2 (ru) 2016-07-20

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EP (1) EP2547205B1 (enExample)
JP (1) JP2013522326A (enExample)
CN (1) CN103025159A (enExample)
AU (1) AU2011227023B2 (enExample)
BR (1) BR112012023660B8 (enExample)
CA (2) CA2793527A1 (enExample)
DK (1) DK2547205T3 (enExample)
ES (1) ES2987670T3 (enExample)
FI (1) FI2547205T3 (enExample)
HR (1) HRP20240658T1 (enExample)
LT (1) LT2547205T (enExample)
PL (1) PL2547205T3 (enExample)
RS (1) RS65536B1 (enExample)
RU (1) RU2591823C2 (enExample)
SI (1) SI2547205T1 (enExample)
SM (1) SMT202400193T1 (enExample)
WO (1) WO2011116399A1 (enExample)

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JP2018511645A (ja) 2015-04-17 2018-04-26 ボストン バイオメディカル, インコーポレイテッド 癌を治療するための方法
JP2018521979A (ja) 2015-06-03 2018-08-09 ボストン バイオメディカル, インコーポレイテッド 癌の治療に使用するための癌幹細胞性阻害剤および免疫療法剤を含む組成物
JP6871919B2 (ja) 2015-06-16 2021-05-19 ナノファギックス エルエルシー 薬物送達及びイメージング化学コンジュゲート、製剤及びその使用方法
WO2017013270A1 (en) 2015-07-23 2017-01-26 Universite De Strasbourg Use of leptin signaling inhibitor for protecting kidneys from patients having ciliopathy
EP3405189A1 (en) 2016-01-20 2018-11-28 Boston Biomedical, Inc. Methods for treating cancer
WO2018005444A2 (en) 2016-06-28 2018-01-04 Boston Biomedical, Inc. Methods for treating cancer
WO2018098352A2 (en) 2016-11-22 2018-05-31 Jun Oishi Targeting kras induced immune checkpoint expression
CA3045306A1 (en) 2016-11-29 2018-06-07 Boston Biomedical, Inc. Naphthofuran derivatives, preparation, and methods of use thereof
CA3062656A1 (en) 2017-05-17 2018-11-22 Boston Biomedical, Inc. Methods for treating cancer
WO2019173646A1 (en) * 2018-03-08 2019-09-12 Exxonmobil Research And Engineering Company Spirocentric compounds and polymers thereof
CN113164438B (zh) 2018-10-12 2025-03-18 北京强新生物科技有限公司 治疗化疗难治性癌症的新联合用药方案
CN111825644B (zh) * 2019-04-18 2023-07-28 中国医学科学院药物研究所 2,3-二氢萘并[2,3-b]呋喃-4,9-二酮类化合物及其制备方法和用途
CN117350965A (zh) * 2023-10-07 2024-01-05 中国原子能科学研究院 对象内放射性微球的指标预估装置

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BR112012023660B8 (pt) 2021-05-25
CN103025159A (zh) 2013-04-03
RS65536B1 (sr) 2024-06-28
LT2547205T (lt) 2024-06-10
PL2547205T3 (pl) 2024-07-08
AU2011227023B2 (en) 2015-05-28
CA2793527A1 (en) 2011-09-22
ES2987670T3 (es) 2024-11-15
BR112012023660B1 (pt) 2021-05-18
HRP20240658T1 (hr) 2024-08-16
JP2013522326A (ja) 2013-06-13
US20170319537A1 (en) 2017-11-09
DK2547205T3 (da) 2024-05-27
CA2946890A1 (en) 2011-09-22
RU2012144420A (ru) 2014-04-27
AU2011227023A1 (en) 2012-09-27
US20130028944A1 (en) 2013-01-31
BR112012023660A2 (pt) 2015-09-15
FI2547205T3 (fi) 2024-05-27
US9730909B2 (en) 2017-08-15
SMT202400193T1 (it) 2024-07-09
EP2547205B1 (en) 2024-03-20
EP2547205A1 (en) 2013-01-23
WO2011116399A1 (en) 2011-09-22
SI2547205T1 (sl) 2024-08-30
EP2547205A4 (en) 2013-08-14

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