CA2786973C - 6-amino-2-{[(1s)-1-methylbutyl] oxy}-9-[5-(1-piperidinyl)-7,9-dihydro-8h-purin-8-one maleate - Google Patents
6-amino-2-{[(1s)-1-methylbutyl] oxy}-9-[5-(1-piperidinyl)-7,9-dihydro-8h-purin-8-one maleate Download PDFInfo
- Publication number
- CA2786973C CA2786973C CA2786973A CA2786973A CA2786973C CA 2786973 C CA2786973 C CA 2786973C CA 2786973 A CA2786973 A CA 2786973A CA 2786973 A CA2786973 A CA 2786973A CA 2786973 C CA2786973 C CA 2786973C
- Authority
- CA
- Canada
- Prior art keywords
- purin
- dihydro
- methylbutyl
- piperidinyl
- oxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- C—CHEMISTRY; METALLURGY
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- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/18—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 one oxygen and one nitrogen atom, e.g. guanine
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
- A61K31/522—Purines, e.g. adenine having oxo groups directly attached to the heterocyclic ring, e.g. hypoxanthine, guanine, acyclovir
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
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- Oncology (AREA)
- Otolaryngology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US30301010P | 2010-02-10 | 2010-02-10 | |
| US61/303,010 | 2010-02-10 | ||
| PCT/EP2011/051830 WO2011098452A1 (en) | 2010-02-10 | 2011-02-08 | 6-amino-2-{ [ (1s)-1-methylbutyl] oxy}-9-[5-(1-piperidinyl)-7,9-dihydro-8h-purin-8-one maleate |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2786973A1 CA2786973A1 (en) | 2011-08-18 |
| CA2786973C true CA2786973C (en) | 2018-04-10 |
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Also Published As
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| EP2534149B1 (en) | 2014-10-15 |
| AU2011214468B2 (en) | 2015-05-28 |
| SG182471A1 (en) | 2012-08-30 |
| WO2011098452A1 (en) | 2011-08-18 |
| JP2013519645A (ja) | 2013-05-30 |
| ZA201205995B (en) | 2014-01-29 |
| SI2534149T1 (sl) | 2015-02-27 |
| EA021048B1 (ru) | 2015-03-31 |
| AU2011214468A1 (en) | 2012-08-09 |
| CN102753553A (zh) | 2012-10-24 |
| RS53745B1 (sr) | 2015-06-30 |
| EA201290631A1 (ru) | 2013-03-29 |
| US8703754B2 (en) | 2014-04-22 |
| US20120308609A1 (en) | 2012-12-06 |
| PT2534149E (pt) | 2014-12-23 |
| DK2534149T3 (da) | 2015-01-05 |
| KR20120135408A (ko) | 2012-12-13 |
| BR112012018904A2 (pt) | 2020-09-01 |
| PL2534149T3 (pl) | 2015-03-31 |
| CA2786973A1 (en) | 2011-08-18 |
| EP2534149A1 (en) | 2012-12-19 |
| IL220845A (en) | 2016-08-31 |
| SMT201400196B (it) | 2015-01-15 |
| CN102753553B (zh) | 2016-03-30 |
| KR101773541B1 (ko) | 2017-08-31 |
| MX2012009316A (es) | 2012-09-12 |
| ME01926B (me) | 2015-05-20 |
| JP5922587B2 (ja) | 2016-05-24 |
| ES2525826T3 (es) | 2014-12-30 |
| HRP20141258T1 (hr) | 2015-02-27 |
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