CA2786969C - Modified tuberculosis antigens - Google Patents

Modified tuberculosis antigens Download PDF

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Publication number
CA2786969C
CA2786969C CA2786969A CA2786969A CA2786969C CA 2786969 C CA2786969 C CA 2786969C CA 2786969 A CA2786969 A CA 2786969A CA 2786969 A CA2786969 A CA 2786969A CA 2786969 C CA2786969 C CA 2786969C
Authority
CA
Canada
Prior art keywords
seq
polypeptide
residues
sequence
amino acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CA2786969A
Other languages
English (en)
French (fr)
Other versions
CA2786969A1 (en
Inventor
Normand Blais
James Brown
Anne-Marie Gelinas
Pascal Mettens
Dennis Murphy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GlaxoSmithKline Biologicals SA
Glaxo Group Ltd
Original Assignee
GlaxoSmithKline Biologicals SA
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by GlaxoSmithKline Biologicals SA, Glaxo Group Ltd filed Critical GlaxoSmithKline Biologicals SA
Publication of CA2786969A1 publication Critical patent/CA2786969A1/en
Application granted granted Critical
Publication of CA2786969C publication Critical patent/CA2786969C/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/35—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Mycobacteriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/04—Mycobacterium, e.g. Mycobacterium tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A61P31/06—Antibacterial agents for tuberculosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Communicable Diseases (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
CA2786969A 2010-01-27 2011-01-27 Modified tuberculosis antigens Active CA2786969C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US29871010P 2010-01-27 2010-01-27
US61/298,710 2010-01-27
PCT/EP2011/051158 WO2011092253A1 (en) 2010-01-27 2011-01-27 Modified tuberculosis antigens

Publications (2)

Publication Number Publication Date
CA2786969A1 CA2786969A1 (en) 2011-08-04
CA2786969C true CA2786969C (en) 2018-07-24

Family

ID=44318698

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2786969A Active CA2786969C (en) 2010-01-27 2011-01-27 Modified tuberculosis antigens

Country Status (25)

Country Link
US (2) US8932600B2 (enExample)
EP (1) EP2528621B1 (enExample)
JP (2) JP6010463B2 (enExample)
KR (1) KR20120129927A (enExample)
CN (1) CN102869372B (enExample)
AU (1) AU2011209399B2 (enExample)
BR (1) BR112012018669A2 (enExample)
CA (1) CA2786969C (enExample)
CO (1) CO6650338A2 (enExample)
CY (1) CY1119518T1 (enExample)
DK (1) DK2528621T3 (enExample)
EA (1) EA201290590A1 (enExample)
ES (1) ES2614266T3 (enExample)
HR (1) HRP20161608T1 (enExample)
HU (1) HUE031184T2 (enExample)
LT (1) LT2528621T (enExample)
MX (1) MX2012008790A (enExample)
MY (1) MY156697A (enExample)
PH (1) PH12012501550A1 (enExample)
PL (1) PL2528621T3 (enExample)
PT (1) PT2528621T (enExample)
SG (1) SG182573A1 (enExample)
SI (1) SI2528621T1 (enExample)
UA (1) UA110103C2 (enExample)
WO (1) WO2011092253A1 (enExample)

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Also Published As

Publication number Publication date
EA201290590A1 (ru) 2013-03-29
BR112012018669A2 (pt) 2017-09-05
JP2016166193A (ja) 2016-09-15
US20120294882A1 (en) 2012-11-22
MX2012008790A (es) 2012-08-17
CN102869372A (zh) 2013-01-09
HRP20161608T1 (hr) 2017-01-13
CA2786969A1 (en) 2011-08-04
DK2528621T3 (da) 2017-01-02
EP2528621A1 (en) 2012-12-05
JP2013517783A (ja) 2013-05-20
HUE031184T2 (en) 2017-06-28
MY156697A (en) 2016-03-15
US20150093414A1 (en) 2015-04-02
SG182573A1 (en) 2012-08-30
EP2528621B1 (en) 2016-09-21
CY1119518T1 (el) 2018-03-07
AU2011209399A1 (en) 2012-08-23
CO6650338A2 (es) 2013-04-15
JP6503309B2 (ja) 2019-04-17
WO2011092253A1 (en) 2011-08-04
US8932600B2 (en) 2015-01-13
UA110103C2 (uk) 2015-11-25
AU2011209399B2 (en) 2014-04-10
ES2614266T3 (es) 2017-05-30
LT2528621T (lt) 2016-12-12
SI2528621T1 (sl) 2017-01-31
PT2528621T (pt) 2016-12-20
PL2528621T3 (pl) 2017-07-31
PH12012501550A1 (en) 2012-10-22
US9200044B2 (en) 2015-12-01
CN102869372B (zh) 2016-01-20
JP6010463B2 (ja) 2016-10-19
KR20120129927A (ko) 2012-11-28

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