CA2735921C - Process for the synthesis of halogenated cyclic compounds - Google Patents

Process for the synthesis of halogenated cyclic compounds Download PDF

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Publication number
CA2735921C
CA2735921C CA2735921A CA2735921A CA2735921C CA 2735921 C CA2735921 C CA 2735921C CA 2735921 A CA2735921 A CA 2735921A CA 2735921 A CA2735921 A CA 2735921A CA 2735921 C CA2735921 C CA 2735921C
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CA
Canada
Prior art keywords
process according
formula
compound
alkyl group
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2735921A
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English (en)
French (fr)
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CA2735921A1 (en
Inventor
Max Braun
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Solvay SA
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Solvay SA
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Filing date
Publication date
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Publication of CA2735921A1 publication Critical patent/CA2735921A1/en
Application granted granted Critical
Publication of CA2735921C publication Critical patent/CA2735921C/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/803—Processes of preparation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
    • C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
    • C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
    • C07D235/06—Benzimidazoles; Hydrogenated benzimidazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
    • C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
    • C07D239/32—One oxygen, sulfur or nitrogen atom
    • C07D239/34—One oxygen atom
    • C07D239/36—One oxygen atom as doubly bound oxygen atom or as unsubstituted hydroxy radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
CA2735921A 2008-09-30 2009-09-25 Process for the synthesis of halogenated cyclic compounds Expired - Fee Related CA2735921C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP08165547 2008-09-30
EP08165547.4 2008-09-30
PCT/EP2009/062462 WO2010037688A1 (en) 2008-09-30 2009-09-25 Process for the synthesis of halogenated cyclic compounds

Publications (2)

Publication Number Publication Date
CA2735921A1 CA2735921A1 (en) 2010-04-08
CA2735921C true CA2735921C (en) 2017-03-21

Family

ID=40351699

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2735921A Expired - Fee Related CA2735921C (en) 2008-09-30 2009-09-25 Process for the synthesis of halogenated cyclic compounds

Country Status (7)

Country Link
US (2) US8431710B2 (enExample)
EP (1) EP2334645B1 (enExample)
JP (5) JP6180705B2 (enExample)
KR (3) KR20110066201A (enExample)
CN (2) CN106083710B (enExample)
CA (1) CA2735921C (enExample)
WO (1) WO2010037688A1 (enExample)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8519195B2 (en) 2008-07-04 2013-08-27 Solvay Sa Process for the manufacture of alkenones
CA2735921C (en) * 2008-09-30 2017-03-21 Solvay Sa Process for the synthesis of halogenated cyclic compounds
GB0903749D0 (en) * 2009-03-04 2009-04-15 Syngenta Participations Ag Chemical process
WO2011003854A1 (en) 2009-07-06 2011-01-13 Solvay Sa Process for the manufacture of halogenated precursors of alkenones in the presence of a solvent
US8957254B2 (en) 2009-07-06 2015-02-17 Solvay Sa Process for chemical synthesis from an alkenone made from a halogenated precursor
EP2662359A1 (en) 2012-05-08 2013-11-13 Solvay Sa Ionic Liquids, Method for manufacturing thereof, and Electrochemical Devices Comprising the Same
EP2888219B1 (en) * 2012-08-22 2019-02-06 Solvay Sa Process for the manufacture of alkenones
JP6449169B2 (ja) 2012-12-20 2019-01-09 ソルヴェイ（ソシエテ アノニム） 電解質中の成分としての窒素含有複素環式アニオンの塩
JP2016522234A (ja) * 2013-06-20 2016-07-28 ビーエーエスエフ ソシエタス・ヨーロピアＢａｓｆ Ｓｅ ピリジルヒドラジンからピリジルピラゾール化合物及びその誘導体を製造するための方法
EP2987782A1 (en) 2014-08-22 2016-02-24 Solvay SA Distillation process comprising at least two distillation steps to obtain purified halogenated carboxylic acid halide, and use of the purified halogenated carboxylic acid halide
CN107001231A (zh) 2014-11-17 2017-08-01 索尔维公司 包括至少两个蒸馏步骤以获得纯化的卤化的羧酸卤化物的蒸馏方法、以及该纯化的卤化的羧酸卤化物的用途
WO2016079122A1 (en) 2014-11-17 2016-05-26 Solvay Sa A method for producing a chemical compound and apparatus therefor
EP3031791A1 (en) 2014-12-10 2016-06-15 Solvay SA Halogenation process of 1,1-dihaloethene
EP3199522A1 (en) 2016-02-01 2017-08-02 Solvay SA Aminothioate derivatives, production thereof and use
EP3679007A1 (en) 2017-09-04 2020-07-15 Solvay SA Process and intermediate for the manufacture of difluoroacetyl chloride
JP6911143B2 (ja) 2018-11-07 2021-07-28 福建永晶科技股▲ふん▼有限公司Ｆｕｊｉａｎ Ｙｏｎｇｊｉｎｇ Ｔｅｃｈｎｏｌｏｇｙ Ｃｏ．， Ｌｔｄ ピラゾール又はピリミジノンの新しい製造方法
CN120172888A (zh) * 2018-12-27 2025-06-20 科迪华农业科技有限责任公司 磺酰胺除草剂方法中间体的制备
WO2021152055A1 (en) 2020-01-31 2021-08-05 Solvay Sa Process for the manufacture of haloalkyl substituted pyridine compounds
JP2021079146A (ja) * 2021-02-22 2021-05-27 株式会社三洋物産 遊技機
JP7315071B2 (ja) * 2021-03-03 2023-07-26 株式会社三洋物産 遊技機

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EP0664805A1 (en) 1992-10-13 1995-08-02 Smithkline Beecham Plc Heterocyclic -esters or -amides used as 5-ht 4? receptor antagonists
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CA2735921C (en) * 2008-09-30 2017-03-21 Solvay Sa Process for the synthesis of halogenated cyclic compounds
BR112012000279A2 (pt) 2009-07-06 2016-02-23 Solvay processos para preparar e para fabricar um precursor halogenado de uma alquenona, e para preparar uma alquenona
WO2011003854A1 (en) 2009-07-06 2011-01-13 Solvay Sa Process for the manufacture of halogenated precursors of alkenones in the presence of a solvent
DK2451764T3 (en) 2009-07-06 2016-03-29 Solvay Method for producing alkenoner
JP6194245B2 (ja) * 2013-12-27 2017-09-06 株式会社Ｓｕｂａｒｕ 信号機認識装置

Also Published As

Publication number Publication date
EP2334645B1 (en) 2019-11-06
US8431710B2 (en) 2013-04-30
CN102164898A (zh) 2011-08-24
JP2012504153A (ja) 2012-02-16
KR20160131129A (ko) 2016-11-15
JP2015227339A (ja) 2015-12-17
CN106083710A (zh) 2016-11-09
JP2022028792A (ja) 2022-02-16
CN106083710B (zh) 2021-03-12
JP6511346B2 (ja) 2019-05-15
JP6647268B2 (ja) 2020-02-14
JP2018058869A (ja) 2018-04-12
JP6180705B2 (ja) 2017-08-16
US8981115B2 (en) 2015-03-17
KR20110066201A (ko) 2011-06-16
WO2010037688A1 (en) 2010-04-08
US20130237710A1 (en) 2013-09-12
JP2020023533A (ja) 2020-02-13
CA2735921A1 (en) 2010-04-08
EP2334645A1 (en) 2011-06-22
KR20190080972A (ko) 2019-07-08
US20110178297A1 (en) 2011-07-21

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