CA2720473A1 - Compositions and use of epas1 inhibitors - Google Patents
Compositions and use of epas1 inhibitors Download PDFInfo
- Publication number
- CA2720473A1 CA2720473A1 CA2720473A CA2720473A CA2720473A1 CA 2720473 A1 CA2720473 A1 CA 2720473A1 CA 2720473 A CA2720473 A CA 2720473A CA 2720473 A CA2720473 A CA 2720473A CA 2720473 A1 CA2720473 A1 CA 2720473A1
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- Prior art keywords
- nucleic acid
- epas
- cells
- nucleotides
- seq
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/12—Type of nucleic acid catalytic nucleic acids, e.g. ribozymes
- C12N2310/122—Hairpin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2310/00—Structure or type of the nucleic acid
- C12N2310/10—Type of nucleic acid
- C12N2310/14—Type of nucleic acid interfering nucleic acids [NA]
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Biotechnology (AREA)
- Pharmacology & Pharmacy (AREA)
- Zoology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US12306908P | 2008-04-04 | 2008-04-04 | |
| US61/123,069 | 2008-04-04 | ||
| PCT/US2009/002125 WO2009123764A2 (en) | 2008-04-04 | 2009-04-03 | Compositions and use of epas1 inhibitors |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2720473A1 true CA2720473A1 (en) | 2009-10-08 |
Family
ID=41119800
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2720473A Abandoned CA2720473A1 (en) | 2008-04-04 | 2009-04-03 | Compositions and use of epas1 inhibitors |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US8114983B2 (https=) |
| EP (1) | EP2283133A2 (https=) |
| JP (1) | JP2011516065A (https=) |
| KR (1) | KR20100127880A (https=) |
| CN (1) | CN102037123A (https=) |
| AU (1) | AU2009232355A1 (https=) |
| BR (1) | BRPI0911332A2 (https=) |
| CA (1) | CA2720473A1 (https=) |
| IL (1) | IL208403A0 (https=) |
| WO (1) | WO2009123764A2 (https=) |
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| ES2377318T3 (es) | 2002-09-06 | 2012-03-26 | Cerulean Pharma Inc. | Polímeros a base de ciclodextrina para el suministro de los agentes terapéuticos enlazados covalentemente a ellos |
| US20080176958A1 (en) | 2007-01-24 | 2008-07-24 | Insert Therapeutics, Inc. | Cyclodextrin-based polymers for therapeutics delivery |
| WO2012174224A2 (en) * | 2011-06-17 | 2012-12-20 | Calando Pharmaceuticals, Inc. | Methods for administering nucleic acid-based therapeutics |
| SI3366775T2 (sl) * | 2011-11-18 | 2025-12-31 | Alnylam Pharmaceuticals, Inc. | Modificirana sredstva RNAI |
| US20140094432A1 (en) | 2012-10-02 | 2014-04-03 | Cerulean Pharma Inc. | Methods and systems for polymer precipitation and generation of particles |
| CN105247051A (zh) * | 2013-02-28 | 2016-01-13 | 箭头研究公司 | 治疗epas1相关疾病的有机组合物 |
| CN103993016B (zh) * | 2014-04-25 | 2015-12-30 | 浙江大学 | Hif2a基因突变体及其检测与应用 |
| AR104754A1 (es) * | 2015-05-29 | 2017-08-09 | Arrowhead Pharmaceuticals Inc | Agentes de unión de tetrapéptido escindibles biológicamente |
| US9730867B2 (en) | 2016-01-06 | 2017-08-15 | The Procter & Gamble Company | Methods of forming a slurry with microcapsules formed from phosphate esters |
| US9732303B2 (en) | 2016-01-06 | 2017-08-15 | The Procter & Gamble Company | Microcapsules formed from phosphate esters and compositions containing same |
| US10154947B2 (en) | 2016-01-06 | 2018-12-18 | The Procter & Gamble Company | Antiperspirant composition |
| JP6890834B2 (ja) * | 2016-02-25 | 2021-06-18 | 国立大学法人九州大学 | アトピー性皮膚炎モデル非ヒト動物及びその使用 |
| WO2019075419A1 (en) * | 2017-10-13 | 2019-04-18 | Dicerna Pharmaceuticals, Inc. | METHODS AND COMPOSITIONS FOR INHIBITING LDHA EXPRESSION |
| EP3713644B1 (en) | 2017-11-20 | 2024-08-07 | University of Georgia Research Foundation, Inc. | Compositions and methods for modulating hif-2a to improve muscle generation and repair |
| US20210002641A1 (en) * | 2018-03-16 | 2021-01-07 | The Regents Of The University Of Michigan | Compositions and methods for treating graves disease |
| SG11202105577TA (en) * | 2019-01-09 | 2021-06-29 | Arrowhead Pharmaceuticals Inc | Rnai agents for inhibiting expression of hif-2 alpha (epas1), compositions thereof, and methods of use |
| CN110251486A (zh) * | 2019-07-31 | 2019-09-20 | 中山大学 | 可用于治疗银屑病的阳离子聚合物及颗粒 |
| CN119662652B (zh) * | 2024-12-24 | 2025-09-02 | 中国人民解放军总医院 | 一种启动子及其应用 |
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-
2009
- 2009-04-03 AU AU2009232355A patent/AU2009232355A1/en not_active Abandoned
- 2009-04-03 CN CN2009801187987A patent/CN102037123A/zh active Pending
- 2009-04-03 US US12/384,475 patent/US8114983B2/en not_active Expired - Fee Related
- 2009-04-03 BR BRPI0911332A patent/BRPI0911332A2/pt not_active Application Discontinuation
- 2009-04-03 EP EP09727168A patent/EP2283133A2/en not_active Withdrawn
- 2009-04-03 WO PCT/US2009/002125 patent/WO2009123764A2/en not_active Ceased
- 2009-04-03 KR KR1020107024671A patent/KR20100127880A/ko not_active Ceased
- 2009-04-03 CA CA2720473A patent/CA2720473A1/en not_active Abandoned
- 2009-04-03 JP JP2011502994A patent/JP2011516065A/ja active Pending
-
2010
- 2010-10-03 IL IL208403A patent/IL208403A0/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2011516065A (ja) | 2011-05-26 |
| KR20100127880A (ko) | 2010-12-06 |
| BRPI0911332A2 (pt) | 2019-09-24 |
| US20100010071A1 (en) | 2010-01-14 |
| CN102037123A (zh) | 2011-04-27 |
| AU2009232355A1 (en) | 2009-10-08 |
| US8114983B2 (en) | 2012-02-14 |
| EP2283133A2 (en) | 2011-02-16 |
| WO2009123764A3 (en) | 2010-02-11 |
| WO2009123764A2 (en) | 2009-10-08 |
| IL208403A0 (en) | 2010-12-30 |
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| FZDE | Discontinued |
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