CA2695309A1 - Methods for recombinant manufacturing of anti-rsv antibodies - Google Patents
Methods for recombinant manufacturing of anti-rsv antibodies Download PDFInfo
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- CA2695309A1 CA2695309A1 CA2695309A CA2695309A CA2695309A1 CA 2695309 A1 CA2695309 A1 CA 2695309A1 CA 2695309 A CA2695309 A CA 2695309A CA 2695309 A CA2695309 A CA 2695309A CA 2695309 A1 CA2695309 A1 CA 2695309A1
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- antibody
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Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
- C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
- C07K16/1027—Paramyxoviridae, e.g. respiratory syncytial virus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
- A61K2039/507—Comprising a combination of two or more separate antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Virology (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (5)
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| US60/971,404 | 2007-09-11 | ||
| PCT/DK2008/050218 WO2009030237A2 (en) | 2007-09-07 | 2008-09-04 | Methods for recombinant manufacturing of anti-rsv antibodies |
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| CA2695309A1 true CA2695309A1 (en) | 2009-03-12 |
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| BR (1) | BRPI0817079A2 (enExample) |
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| ZA (1) | ZA201000756B (enExample) |
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| DK2032701T3 (da) * | 2006-06-23 | 2014-02-10 | Alethia Biotherapeutics Inc | Polynukleotider og polypeptider, der er inddraget i cancer |
| ATE521704T1 (de) * | 2007-03-01 | 2011-09-15 | Symphogen As | Verfahren zur klonierung verwandter antikörper |
| EP1997830A1 (en) | 2007-06-01 | 2008-12-03 | AIMM Therapeutics B.V. | RSV specific binding molecules and means for producing them |
| EP2331689A4 (en) * | 2008-08-29 | 2012-10-31 | Symphogen As | METHOD OF CLONING AVIAN ORIGIN ANTIBODIES |
| JP5781932B2 (ja) | 2008-11-03 | 2015-09-24 | アレシア・バイオセラピューティクス・インコーポレーテッド | 腫瘍抗原の生物活性を特異的にブロックする抗体 |
| GB0905023D0 (en) | 2009-03-24 | 2009-05-06 | Univ Erasmus Medical Ct | Binding molecules |
| CN102656189B (zh) * | 2009-08-13 | 2014-10-08 | 克鲁塞尔荷兰公司 | 针对人呼吸道合胞病毒(rsv)的抗体以及使用方法 |
| CN104628850B (zh) * | 2009-10-06 | 2020-07-28 | 医学免疫有限公司 | Rsv-特异性结合分子 |
| JP5734988B2 (ja) * | 2009-10-06 | 2015-06-17 | メディミューン リミテド | Ｒｓｖ特異的結合分子 |
| US8568726B2 (en) | 2009-10-06 | 2013-10-29 | Medimmune Limited | RSV specific binding molecule |
| CN104131035A (zh) | 2009-12-10 | 2014-11-05 | 瑞泽恩制药公司 | 生产重链抗体的小鼠 |
| NZ703035A (en) | 2010-07-09 | 2016-06-24 | Crucell Holland Bv | Anti-human respiratory syncytial virus (rsv) antibodies and methods of use |
| EP2691421B1 (en) | 2011-03-31 | 2016-11-09 | Alethia Biotherapeutics Inc. | Antibodies against kidney associated antigen 1 and antigen binding fragments thereof |
| EA201992513A1 (ru) | 2012-01-09 | 2020-05-31 | Адс Терапьютикс Са | Способ лечения рака груди |
| AR092219A1 (es) * | 2012-08-23 | 2015-04-08 | Seattle Genetics Inc | Conjugados anticuerpo-farmaco (adc) que se unen a proteinas 158p1d7 |
| JP5996707B2 (ja) * | 2015-04-15 | 2016-09-21 | メディミューン リミテド | Ｒｓｖ特異的結合分子 |
| PH12017502013B1 (en) | 2015-05-07 | 2022-07-22 | Agenus Inc | Anti-ox40 antibodies and methods of use thereof |
| EP3383914A4 (en) * | 2015-12-02 | 2019-10-30 | Agenus Inc. | ANTI-OX40 ANTIBODIES AND METHOD OF USE THEREOF |
| WO2017096182A1 (en) * | 2015-12-03 | 2017-06-08 | Agenus Inc. | Anti-ox40 antibodies and methods of use thereof |
| EP3529272A2 (en) | 2016-10-21 | 2019-08-28 | Adimab, LLC | Anti-respiratory syncytial virus antibodies, and methods of their generation and use |
| EP3974447A3 (en) | 2016-10-21 | 2022-09-07 | Adimab, LLC | Anti-respiratory syncytial virus antibodies, and methods of their generation and use |
| JP2020503844A (ja) | 2016-10-21 | 2020-02-06 | アディマブ， エルエルシー | 抗呼吸器合胞体ウイルス抗体、及び、それらの生成及び使用の方法 |
| CA3041340A1 (en) | 2016-11-09 | 2018-05-17 | Agenus Inc. | Anti-ox40 antibodies, anti-gitr antibodies, and methods of use thereof |
| WO2018150029A1 (en) * | 2017-02-17 | 2018-08-23 | Institut Pasteur | Generation of monoclonal antibodies targeting respiratory syncytial virus (rsv) using regulatory b cells from newborns (nbregs) |
| WO2021202463A1 (en) | 2020-03-30 | 2021-10-07 | Danisco Us Inc | Anti-rsv antibodies |
| WO2021253002A1 (en) | 2020-06-12 | 2021-12-16 | Gigagen, Inc. | Recombinant polyclonal proteins targeting covid-19 and methods of use thereof |
| WO2022031834A1 (en) | 2020-08-05 | 2022-02-10 | Gigagen, Inc. | Recombinant polyclonal proteins targeting zika and methods of use thereof |
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| US20060275766A1 (en) * | 2003-01-07 | 2006-12-07 | Haurum John S | Method for manufacturing recombinant polyclonal proteins |
| TWI333977B (en) * | 2003-09-18 | 2010-12-01 | Symphogen As | Method for linking sequences of interest |
| WO2006007850A1 (en) * | 2004-07-20 | 2006-01-26 | Symphogen A/S | Anti-rhesus d recombinant polyclonal antibody and methods of manufacture |
| CA2574146C (en) * | 2004-07-20 | 2015-06-30 | Symphogen A/S | A procedure for structural characterization of a recombinant polyclonal protein or a polyclonal cell line |
| AU2006322445B2 (en) * | 2005-12-05 | 2011-05-12 | Symphogen A/S | Anti-orthopoxvirus recombinant polyclonal antibody |
| KR20080113223A (ko) * | 2006-03-06 | 2008-12-29 | 심포젠 에이/에스 | 호흡기세포 융합 바이러스 감염 치료용 재조합 폴리클로날 항체 |
| WO2008106980A2 (en) * | 2007-03-06 | 2008-09-12 | Symphogen A/S | Recombinant antibodies for treatment of respiratory syncytial virus infections |
| MX2009012526A (es) * | 2007-05-25 | 2009-12-09 | Symphogen As | Metodo para fabricar una proteina policlonal recombinante. |
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2008
- 2008-09-04 KR KR1020107007563A patent/KR20100087283A/ko not_active Withdrawn
- 2008-09-04 MX MX2010002044A patent/MX2010002044A/es not_active Application Discontinuation
- 2008-09-04 CN CN200880106131A patent/CN101821289A/zh active Pending
- 2008-09-04 BR BRPI0817079A patent/BRPI0817079A2/pt not_active IP Right Cessation
- 2008-09-04 WO PCT/DK2008/050218 patent/WO2009030237A2/en not_active Ceased
- 2008-09-04 JP JP2010523277A patent/JP2011514139A/ja active Pending
- 2008-09-04 AU AU2008295248A patent/AU2008295248A1/en not_active Abandoned
- 2008-09-04 RU RU2010113510/10A patent/RU2010113510A/ru not_active Application Discontinuation
- 2008-09-04 CA CA2695309A patent/CA2695309A1/en not_active Abandoned
- 2008-09-04 EP EP08784476A patent/EP2185590A2/en not_active Withdrawn
- 2008-09-05 TW TW097134053A patent/TW200925279A/zh unknown
- 2008-09-05 US US12/230,885 patent/US20090137003A1/en not_active Abandoned
-
2010
- 2010-02-01 ZA ZA2010/00756A patent/ZA201000756B/en unknown
-
2011
- 2011-09-23 US US13/243,768 patent/US20120009623A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| BRPI0817079A2 (pt) | 2016-10-11 |
| WO2009030237A2 (en) | 2009-03-12 |
| AU2008295248A1 (en) | 2009-03-12 |
| RU2010113510A (ru) | 2011-10-20 |
| US20090137003A1 (en) | 2009-05-28 |
| JP2011514139A (ja) | 2011-05-06 |
| US20120009623A1 (en) | 2012-01-12 |
| CN101821289A (zh) | 2010-09-01 |
| WO2009030237A3 (en) | 2009-04-30 |
| MX2010002044A (es) | 2010-03-18 |
| TW200925279A (en) | 2009-06-16 |
| EP2185590A2 (en) | 2010-05-19 |
| ZA201000756B (en) | 2010-10-27 |
| KR20100087283A (ko) | 2010-08-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |
Effective date: 20130904 |