CA2691746C - Use of alpha-ketoglutarate in the treatment of hypertension - Google Patents
Use of alpha-ketoglutarate in the treatment of hypertension Download PDFInfo
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- CA2691746C CA2691746C CA2691746A CA2691746A CA2691746C CA 2691746 C CA2691746 C CA 2691746C CA 2691746 A CA2691746 A CA 2691746A CA 2691746 A CA2691746 A CA 2691746A CA 2691746 C CA2691746 C CA 2691746C
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- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
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- A—HUMAN NECESSITIES
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- A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
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- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
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- A—HUMAN NECESSITIES
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- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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- Coloring Foods And Improving Nutritive Qualities (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0701602-5 | 2007-07-02 | ||
| SE0701602 | 2007-07-02 | ||
| PCT/SE2008/050797 WO2009005464A1 (en) | 2007-07-02 | 2008-06-27 | New use of known pharmacologically active chemical compounds |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2691746A1 CA2691746A1 (en) | 2009-01-08 |
| CA2691746C true CA2691746C (en) | 2016-02-02 |
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| Application Number | Title | Priority Date | Filing Date |
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| CA2691746A Expired - Fee Related CA2691746C (en) | 2007-07-02 | 2008-06-27 | Use of alpha-ketoglutarate in the treatment of hypertension |
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| Country | Link |
|---|---|
| US (1) | US20110039935A1 (enExample) |
| EP (1) | EP2173336B1 (enExample) |
| JP (1) | JP5735274B2 (enExample) |
| KR (1) | KR20100039874A (enExample) |
| CN (1) | CN101730532B (enExample) |
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| BR (1) | BRPI0814184A2 (enExample) |
| CA (1) | CA2691746C (enExample) |
| EA (1) | EA018554B1 (enExample) |
| MX (1) | MX2009013937A (enExample) |
| WO (1) | WO2009005464A1 (enExample) |
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| ES2992382T3 (es) | 2014-02-12 | 2024-12-11 | Univ California | Composiciones y métodos para tratar el envejecimiento y enfermedades y síntomas relacionados con la edad |
| EP3007503B1 (en) | 2014-03-20 | 2021-06-30 | Huawei Device Co., Ltd. | Signal transmission method, user equipment, and base station |
| IL270162B2 (en) * | 2017-04-25 | 2025-07-01 | Buck Inst Res Aging | ?-ketoglutarate (akg) and (i) a vitamin a compound, or (ii) a vitamin d compound, for use in delaying onset or delaying progression of frailty |
| IL281761B2 (en) | 2018-09-25 | 2025-09-01 | Ponce De Leon Health Designated Activity Company | Process for preparing calcium alpha-ketoglutarate |
| EP3980000A4 (en) * | 2019-06-10 | 2023-06-21 | Buck Institute for Research on Aging | METHODS AND COMPOSITIONS FOR ALTERING THE SENSCENCE OF ASSOCIATED SECRETORY PHENOTYPES |
| JP2023533452A (ja) * | 2020-06-23 | 2023-08-03 | ユニバーシティ オブ ピッツバーグ － オブ ザ コモンウェルス システム オブ ハイヤー エデュケイション | 動脈瘤を処置するための求電子化合物および求電子プロドラッグ |
| CN117530940A (zh) * | 2023-10-11 | 2024-02-09 | 四川大学华西第二医院 | α-酮戊二酸在制备促髓鞘修复、改善神经炎症的药物中的应用 |
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| SE9402027D0 (sv) * | 1994-06-10 | 1994-06-10 | Pharmacia Ab | Energy substrates |
| JP2000093096A (ja) * | 1998-09-21 | 2000-04-04 | Snow Brand Milk Prod Co Ltd | ゼリー状食品 |
| DE19929993C2 (de) * | 1999-06-30 | 2001-07-05 | Sueddeutsche Kalkstickstoff | Kreatin-alpha-ketoglutarate, Verfahren zu ihrer Herstellung und ihre Verwendung |
| CN1203168C (zh) * | 2001-08-17 | 2005-05-25 | 杨志东 | 一种制备食疗保健醋的方法及用该方法生产的食疗保健醋 |
| US20040220265A1 (en) * | 2002-07-25 | 2004-11-04 | Celluar Sciences, Inc. | Method for treating pulmonary disease states in mammals by altering indigenous in vivo levels of nitric oxide |
| US7194301B2 (en) * | 2003-10-06 | 2007-03-20 | Transneuronic, Inc. | Method for screening and treating patients at risk of medical disorders |
| PL368572A1 (en) * | 2004-06-17 | 2005-12-27 | Sgp & Sons Ab | Pharmaceutical compound for prevention and therapy of increased level of cholesterol, ldl and triglycerides as well as application of the pharmaceutical compound as an agent acting against atherosclerosis and used in circulatory system affections |
| PL370937A1 (pl) * | 2004-10-29 | 2006-05-02 | Sgp & Sons Ab | Preparat żywieniowy i/lub farmaceutyczny do stosowania w profilaktyce i leczeniu niedoborów wchłaniania mikroelementów z przewodu pokarmowego oraz zastosowanie preparatu farmaceutycznego jako czynnika stymulującego wchłanianie mikroelementów z przewodu pokarmowego do krwi |
| WO2007002365A2 (en) * | 2005-06-24 | 2007-01-04 | Albert Einstein College Of Medicine Of Yeshiva University | Modulation of amino acid metabolism in the hypothalamus |
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- 2008-06-27 KR KR1020107002345A patent/KR20100039874A/ko not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| AU2008271307B2 (en) | 2013-10-24 |
| CN101730532A (zh) | 2010-06-09 |
| CA2691746A1 (en) | 2009-01-08 |
| EA201070084A1 (ru) | 2010-10-29 |
| JP5735274B2 (ja) | 2015-06-17 |
| BRPI0814184A2 (pt) | 2015-03-03 |
| WO2009005464A1 (en) | 2009-01-08 |
| US20110039935A1 (en) | 2011-02-17 |
| EP2173336A4 (en) | 2010-11-10 |
| KR20100039874A (ko) | 2010-04-16 |
| EP2173336B1 (en) | 2016-03-30 |
| JP2010532348A (ja) | 2010-10-07 |
| HK1140423A1 (en) | 2010-10-15 |
| EP2173336A1 (en) | 2010-04-14 |
| MX2009013937A (es) | 2010-04-30 |
| EA018554B1 (ru) | 2013-08-30 |
| AU2008271307A1 (en) | 2009-01-08 |
| CN101730532B (zh) | 2012-05-30 |
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