CA2683920C - Device for handling liquid samples - Google Patents

Device for handling liquid samples Download PDF

Info

Publication number
CA2683920C
CA2683920C CA2683920A CA2683920A CA2683920C CA 2683920 C CA2683920 C CA 2683920C CA 2683920 A CA2683920 A CA 2683920A CA 2683920 A CA2683920 A CA 2683920A CA 2683920 C CA2683920 C CA 2683920C
Authority
CA
Canada
Prior art keywords
liquid
sample
flow
different
sink
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2683920A
Other languages
English (en)
French (fr)
Other versions
CA2683920A1 (en
Inventor
David Bergman
Pierre Kreueger
David Roennholm
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Amic AB
Original Assignee
Amic AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Amic AB filed Critical Amic AB
Publication of CA2683920A1 publication Critical patent/CA2683920A1/en
Application granted granted Critical
Publication of CA2683920C publication Critical patent/CA2683920C/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/502746—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means for controlling flow resistance, e.g. flow controllers, baffles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
    • B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
    • B01L3/50273—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by the means or forces applied to move the fluids
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00—Subject matter not provided for in other groups of this subclass
    • F16K99/0001—Microvalves
    • F16K99/0003—Constructional types of microvalves; Details of the cutting-off member
    • F16K99/0017—Capillary or surface tension valves, e.g. using electro-wetting or electro-capillarity effects
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0809—Geometry, shape and general structure rectangular shaped
    • B01L2300/0816—Cards, e.g. flat sample carriers usually with flow in two horizontal directions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2300/00—Additional constructional details
    • B01L2300/08—Geometry, shape and general structure
    • B01L2300/0887—Laminated structure
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/04—Moving fluids with specific forces or mechanical means
    • B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
    • B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L2400/00—Moving or stopping fluids
    • B01L2400/08—Regulating or influencing the flow resistance
    • B01L2400/084—Passive control of flow resistance
    • B01L2400/086—Passive control of flow resistance using baffles or other fixed flow obstructions
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16K—VALVES; TAPS; COCKS; ACTUATING-FLOATS; DEVICES FOR VENTING OR AERATING
    • F16K99/00—Subject matter not provided for in other groups of this subclass
    • F16K2099/0082—Microvalves adapted for a particular use
    • F16K2099/0084—Chemistry or biology, e.g. "lab-on-a-chip" technology

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Clinical Laboratory Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Sampling And Sample Adjustment (AREA)
CA2683920A 2007-04-16 2008-04-15 Device for handling liquid samples Expired - Fee Related CA2683920C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US92379807P 2007-04-16 2007-04-16
SE0700930-1 2007-04-16
US60/923,798 2007-04-16
SE0700930A SE529978C2 (sv) 2007-04-16 2007-04-16 Analysanordning för vätskeformiga prov
PCT/SE2008/050424 WO2008127191A1 (en) 2007-04-16 2008-04-15 Device for handling liquid samples

Publications (2)

Publication Number Publication Date
CA2683920A1 CA2683920A1 (en) 2008-10-23
CA2683920C true CA2683920C (en) 2016-05-31

Family

ID=38935813

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2683920A Expired - Fee Related CA2683920C (en) 2007-04-16 2008-04-15 Device for handling liquid samples

Country Status (6)

Country Link
EP (1) EP2134472A4 (de)
JP (1) JP5425757B2 (de)
CN (1) CN101678355B (de)
CA (1) CA2683920C (de)
SE (1) SE529978C2 (de)
WO (1) WO2008127191A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9216413B2 (en) 2009-07-07 2015-12-22 Boehringer Ingelheim Microparts Gmbh Plasma separation reservoir
EP2618153B1 (de) * 2012-01-20 2015-03-18 Ortho-Clinical Diagnostics, Inc. Steuerung des Fluidstroms durch eine Analysevorrichtung
US8895293B2 (en) * 2012-01-20 2014-11-25 Ortho-Clinical Diagnostics, Inc. Assay device having uniform flow around corners
JP6278772B2 (ja) * 2014-03-19 2018-02-14 テルモ株式会社 血糖値測定用チップ
CN107003329B (zh) * 2014-11-28 2019-05-31 东洋制罐集团控股株式会社 微细送液结构体、以及分析装置
CN107219170B (zh) * 2017-07-24 2023-09-19 苏州鼎实医疗科技有限公司 试剂片
WO2022058470A1 (en) * 2020-09-17 2022-03-24 Katholieke Universiteit Leuven Activation and pressure balancing mechanism
WO2024211341A2 (en) * 2023-04-03 2024-10-10 Burst Diagnostics Llc Chemiluminescence microfluidic immunoassay device and methods of use thereof

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0610900A (ja) * 1992-04-27 1994-01-21 Canon Inc 液体移動方法及び移動装置ならびにこれを利用した測定装置
US6156270A (en) * 1992-05-21 2000-12-05 Biosite Diagnostics, Inc. Diagnostic devices and apparatus for the controlled movement of reagents without membranes
JP3213566B2 (ja) * 1996-04-26 2001-10-02 アークレイ株式会社 検体分析用具およびそれを用いた検体分析方法並びに検体分析装置
WO2000022436A1 (en) * 1998-10-13 2000-04-20 Biomicro Systems, Inc. Fluid circuit components based upon passive fluid dynamics
US6571651B1 (en) * 2000-03-27 2003-06-03 Lifescan, Inc. Method of preventing short sampling of a capillary or wicking fill device
SE0201738D0 (sv) * 2002-06-07 2002-06-07 Aamic Ab Micro-fluid structures
KR100444751B1 (ko) * 2002-11-11 2004-08-16 한국전자통신연구원 표면장력에 의한 유체제어 소자
US20060043284A1 (en) * 2002-11-29 2006-03-02 Nec Corporation Micro chip, liquid feeding method using the micro chip, and mass analyzing system
DE10302720A1 (de) * 2003-01-23 2004-08-05 Steag Microparts Gmbh Mikrofluidischer Schalter zum Anhalten des Flüssigkeitsstroms während eines Zeitintervalls
EP1525916A1 (de) * 2003-10-23 2005-04-27 F. Hoffmann-La Roche Ag Auslösedurchflussvorrichtung
EP1525919A1 (de) * 2003-10-23 2005-04-27 F. Hoffmann-La Roche Ag Auslösedurchflussvorrichtung
CN1238713C (zh) * 2003-11-01 2006-01-25 浙江大学 集成微型电磁泵式毛细管电泳芯片
GB2410086A (en) * 2004-01-14 2005-07-20 British Biocell Internat Ltd Assay devices having flow block(s) to determine flow of liquids
US20070160474A1 (en) * 2004-02-06 2007-07-12 Kazuhiro Iida Regulation structure, separation device and gradient forming device, and microchip using the same
SE0400662D0 (sv) * 2004-03-24 2004-03-24 Aamic Ab Assay device and method
SE527036C2 (sv) * 2004-06-02 2005-12-13 Aamic Ab Analysanordning med reglerat flöde och motsvarande förfarande
US7682817B2 (en) * 2004-12-23 2010-03-23 Kimberly-Clark Worldwide, Inc. Microfluidic assay devices
CA2598513A1 (en) * 2005-02-25 2006-08-31 Inverness Medical Switzerland Gmbh Fluidic gating device
JPWO2006098370A1 (ja) * 2005-03-16 2008-08-28 日本電気株式会社 流路の実効的な通過時間の調整機構を具える遅延回路、マイクロチップ、およびその作製方法

Also Published As

Publication number Publication date
SE0700930L (sv) 2008-01-22
JP5425757B2 (ja) 2014-02-26
CA2683920A1 (en) 2008-10-23
CN101678355B (zh) 2012-11-14
EP2134472A4 (de) 2014-10-01
WO2008127191A1 (en) 2008-10-23
JP2010525319A (ja) 2010-07-22
SE529978C2 (sv) 2008-01-22
EP2134472A1 (de) 2009-12-23
CN101678355A (zh) 2010-03-24

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Effective date: 20130404

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Effective date: 20190415