CA2671828C - Iron(iii)-carbohydrate based phosphate adsorbent - Google Patents

Iron(iii)-carbohydrate based phosphate adsorbent Download PDF

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Publication number
CA2671828C
CA2671828C CA2671828A CA2671828A CA2671828C CA 2671828 C CA2671828 C CA 2671828C CA 2671828 A CA2671828 A CA 2671828A CA 2671828 A CA2671828 A CA 2671828A CA 2671828 C CA2671828 C CA 2671828C
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CA
Canada
Prior art keywords
iron
phosphate
iii
adsorbent
starch
Prior art date
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Active
Application number
CA2671828A
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English (en)
French (fr)
Other versions
CA2671828A1 (en
Inventor
Michael Ambuehl
Corine Gessier-Vial
Christa Hartmann
Daniel Kaufmann
Ernst Kuesters
Ulrich Meier
Andreas Meyer
Nabila Sekkat
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Elanco Tiergesundheit AG
Original Assignee
Novartis AG
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Priority claimed from EP06126122A external-priority patent/EP1932807A1/en
Application filed by Novartis AG filed Critical Novartis AG
Publication of CA2671828A1 publication Critical patent/CA2671828A1/en
Application granted granted Critical
Publication of CA2671828C publication Critical patent/CA2671828C/en
Active legal-status Critical Current
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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/26—Iron; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/02—Nutrients, e.g. vitamins, minerals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/18—Drugs for disorders of the endocrine system of the parathyroid hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/02—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material
    • B01J20/06—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising inorganic material comprising oxides or hydroxides of metals not provided for in group B01J20/04
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/223—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material containing metals, e.g. organo-metallic compounds, coordination complexes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28014—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their form
    • B01J20/2803—Sorbents comprising a binder, e.g. for forming aggregated, agglomerated or granulated products
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01G—COMPOUNDS CONTAINING METALS NOT COVERED BY SUBCLASSES C01D OR C01F
    • C01G49/00—Compounds of iron
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01G—COMPOUNDS CONTAINING METALS NOT COVERED BY SUBCLASSES C01D OR C01F
    • C01G49/00—Compounds of iron
    • C01G49/0018—Mixed oxides or hydroxides
    • C—CHEMISTRY; METALLURGY
    • C01—INORGANIC CHEMISTRY
    • C01G—COMPOUNDS CONTAINING METALS NOT COVERED BY SUBCLASSES C01D OR C01F
    • C01G49/00—Compounds of iron
    • C01G49/02—Oxides; Hydroxides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/02—Iron compounds

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Inorganic Chemistry (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Analytical Chemistry (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Obesity (AREA)
  • Rheumatology (AREA)
  • Endocrinology (AREA)
  • Virology (AREA)
  • Epidemiology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Oncology (AREA)
  • Nutrition Science (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • External Artificial Organs (AREA)
CA2671828A 2006-12-14 2007-12-12 Iron(iii)-carbohydrate based phosphate adsorbent Active CA2671828C (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
EP06126101.2 2006-12-14
EP06126122.8 2006-12-14
EP06126122A EP1932807A1 (en) 2006-12-14 2006-12-14 Inorganic compounds
EP06126101 2006-12-14
PCT/EP2007/063832 WO2008071747A1 (en) 2006-12-14 2007-12-12 Iron (iii)-carbohydrate based phosphate adsorbent

Publications (2)

Publication Number Publication Date
CA2671828A1 CA2671828A1 (en) 2008-06-19
CA2671828C true CA2671828C (en) 2012-06-19

Family

ID=38983614

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2671828A Active CA2671828C (en) 2006-12-14 2007-12-12 Iron(iii)-carbohydrate based phosphate adsorbent

Country Status (23)

Country Link
US (2) US8252310B2 (enExample)
JP (1) JP5456969B2 (enExample)
KR (1) KR20090094820A (enExample)
AR (1) AR064301A1 (enExample)
AU (1) AU2007331482B2 (enExample)
BR (1) BRPI0720272A2 (enExample)
CA (1) CA2671828C (enExample)
CL (1) CL2007003606A1 (enExample)
EC (1) ECSP099410A (enExample)
ES (1) ES2526171T3 (enExample)
IL (1) IL198548A0 (enExample)
MA (1) MA30993B1 (enExample)
MX (1) MX2009006307A (enExample)
MY (1) MY151047A (enExample)
NO (1) NO342285B1 (enExample)
NZ (1) NZ576672A (enExample)
PE (1) PE20081381A1 (enExample)
PT (1) PT2319804E (enExample)
RU (1) RU2447933C2 (enExample)
SI (1) SI2319804T1 (enExample)
TN (1) TN2009000214A1 (enExample)
TW (1) TWI465239B (enExample)
WO (1) WO2008071747A1 (enExample)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9720061D0 (en) 1997-09-19 1997-11-19 Crosfield Joseph & Sons Metal compounds as phosphate binders
MY157620A (en) 2006-01-31 2016-06-30 Cytochroma Dev Inc A granular material of a solid water-soluble mixed metal compound capable of binding phosphate
GB0714670D0 (en) 2007-07-27 2007-09-05 Ineos Healthcare Ltd Use
GB0720220D0 (en) 2007-10-16 2007-11-28 Ineos Healthcare Ltd Compound
TWI592159B (zh) 2007-11-16 2017-07-21 威佛（國際）股份有限公司 藥學組成物
JP2009292119A (ja) 2008-06-09 2009-12-17 Alps Electric Co Ltd サーマルヘッド
WO2009150232A2 (en) * 2008-06-13 2009-12-17 Novartis Ag Manufacture process for the preparation of an iron containing phosphate adsorbent
GB0814326D0 (en) * 2008-08-05 2008-09-10 Medical Res Council Phosphate binding materials and their uses
CN102573807A (zh) 2009-07-21 2012-07-11 凯克斯生物制药公司 柠檬酸铁剂型
GB0913525D0 (en) 2009-08-03 2009-09-16 Ineos Healthcare Ltd Method
GB201001779D0 (en) 2010-02-04 2010-03-24 Ineos Healthcare Ltd Composition
DE102011112898A1 (de) 2011-09-08 2013-03-14 Charité - Universitätsmedizin Berlin Nanopartikuläres Phosphatadsorbens basierend auf Maghämit oder Maghämit/Magnetit, dessen Herstellung und Verwendungen
CA2849926C (en) * 2011-10-13 2020-07-21 Vidasym, Inc. Iron-fiber composition, preparation and uses thereof
RU2496722C1 (ru) * 2012-04-10 2013-10-27 Леонид Асхатович Мазитов Способ очистки сточной воды от фосфатов
CN109497565B (zh) 2013-03-08 2021-10-26 上海礼邦医药科技有限公司 金属离子-功能性纤维组分络合物组合物、其制备及用途
HK1216513A1 (zh) * 2013-03-15 2016-11-18 阿普雷奇亚制药有限责任公司 包含左乙拉西坦的快速分散劑型
US9339489B2 (en) * 2013-03-15 2016-05-17 Aprecia Pharmaceuticals Company Rapid disperse dosage form containing levetiracetam
WO2015078900A1 (en) 2013-11-27 2015-06-04 Vifor (International) Ag Pharmaceutical composition, comprising phosphate binder particles
US10172882B2 (en) 2014-06-22 2019-01-08 Dexcel Pharma Technologies Ltd. Pharmaceutical compositions comprising ferric citrate and methods for the production thereof
US9901918B2 (en) * 2015-03-04 2018-02-27 Graver Technologies Llc Hybrid ion exchange material and method for making the same
CN105193844A (zh) * 2015-05-27 2015-12-30 合肥川迪医药技术有限公司 用于制备含δ-羟基氧化铁(多核)及其药物组合物的方法及在高磷血症领域中的应用
WO2017172633A1 (en) * 2016-03-28 2017-10-05 New Sky Energy Intellectual Property Holding Company, Llc Methods of producing ferrihydrite nanoparticle slurries, and systems and products employing the same
WO2020025552A1 (en) 2018-07-30 2020-02-06 Interquim, S.A. Process for preparing an adsorbent for phosphate in aqueous medium
CN115175670B (zh) * 2020-01-16 2024-08-30 威佛费森尤斯医疗肾脏药物有限公司 羟基氧化铁(iii)、蔗糖和一种或更多种淀粉的混合物的颗粒，优选羟基氧化蔗糖铁的颗粒
CN115317494B (zh) * 2022-07-22 2024-02-13 康瑞鑫(天津)药物研究院有限公司 高磷酸盐结合力的蔗糖氢氧化氧铁及其制备方法
WO2025096992A1 (en) * 2023-11-01 2025-05-08 Navinta, Llc Process for isolation of solid ferric derisomaltose

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Also Published As

Publication number Publication date
BRPI0720272A2 (pt) 2014-01-28
MX2009006307A (es) 2009-06-23
ECSP099410A (es) 2009-07-31
HK1133248A1 (en) 2010-03-19
JP2008150375A (ja) 2008-07-03
MA30993B1 (fr) 2009-12-01
NO20092632L (no) 2009-07-14
WO2008071747A1 (en) 2008-06-19
KR20090094820A (ko) 2009-09-08
SI2319804T1 (sl) 2015-01-30
PT2319804E (pt) 2014-11-24
US8252310B2 (en) 2012-08-28
IL198548A0 (en) 2010-02-17
TWI465239B (zh) 2014-12-21
TW200831115A (en) 2008-08-01
AU2007331482A1 (en) 2008-06-19
CA2671828A1 (en) 2008-06-19
JP5456969B2 (ja) 2014-04-02
NO342285B1 (no) 2018-04-30
CL2007003606A1 (es) 2008-07-18
AU2007331482B2 (en) 2011-04-21
US20120126440A1 (en) 2012-05-24
PE20081381A1 (es) 2008-11-12
US20080145410A1 (en) 2008-06-19
AR064301A1 (es) 2009-03-25
ES2526171T3 (es) 2015-01-07
MY151047A (en) 2014-03-31
TN2009000214A1 (en) 2010-10-18
NZ576672A (en) 2012-02-24
RU2009126614A (ru) 2011-01-20
RU2447933C2 (ru) 2012-04-20

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