KR20090094820A - 철(ⅲ)-탄수화물-기재 인산염 흡착제 - Google Patents
철(ⅲ)-탄수화물-기재 인산염 흡착제 Download PDFInfo
- Publication number
- KR20090094820A KR20090094820A KR1020097012145A KR20097012145A KR20090094820A KR 20090094820 A KR20090094820 A KR 20090094820A KR 1020097012145 A KR1020097012145 A KR 1020097012145A KR 20097012145 A KR20097012145 A KR 20097012145A KR 20090094820 A KR20090094820 A KR 20090094820A
- Authority
- KR
- South Korea
- Prior art keywords
- iron
- iii
- phosphate
- phosphate adsorbent
- based phosphate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Ceased
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- 229910019142 PO4 Inorganic materials 0.000 title claims abstract description 199
- 239000010452 phosphate Substances 0.000 title claims abstract description 196
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 title claims abstract description 194
- 239000003463 adsorbent Substances 0.000 title claims abstract description 183
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 title abstract description 105
- 229910052742 iron Inorganic materials 0.000 title abstract description 54
- 201000005991 hyperphosphatemia Diseases 0.000 claims abstract description 15
- 238000011282 treatment Methods 0.000 claims abstract description 11
- 235000021317 phosphate Nutrition 0.000 claims description 196
- 239000000203 mixture Substances 0.000 claims description 114
- VTLYFUHAOXGGBS-UHFFFAOYSA-N Fe3+ Chemical compound [Fe+3] VTLYFUHAOXGGBS-UHFFFAOYSA-N 0.000 claims description 107
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- 239000008107 starch Substances 0.000 claims description 67
- IEECXTSVVFWGSE-UHFFFAOYSA-M iron(3+);oxygen(2-);hydroxide Chemical class [OH-].[O-2].[Fe+3] IEECXTSVVFWGSE-UHFFFAOYSA-M 0.000 claims description 53
- 238000000034 method Methods 0.000 claims description 49
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- 229930006000 Sucrose Natural products 0.000 claims description 38
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- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 claims description 36
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- 229910021519 iron(III) oxide-hydroxide Inorganic materials 0.000 claims description 27
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- 229910000462 iron(III) oxide hydroxide Inorganic materials 0.000 claims description 26
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- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 24
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- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 claims description 6
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- GMRQFYUYWCNGIN-NKMMMXOESA-N calcitriol Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@@H](CCCC(C)(C)O)C)=C\C=C1\C[C@@H](O)C[C@H](O)C1=C GMRQFYUYWCNGIN-NKMMMXOESA-N 0.000 claims description 5
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- BECPQYXYKAMYBN-UHFFFAOYSA-N casein, tech. Chemical compound NCCCCC(C(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(CC(C)C)N=C(O)C(CCC(O)=O)N=C(O)C(CC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(C(C)O)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=N)N=C(O)C(CCC(O)=O)N=C(O)C(CCC(O)=O)N=C(O)C(COP(O)(O)=O)N=C(O)C(CCC(O)=N)N=C(O)C(N)CC1=CC=CC=C1 BECPQYXYKAMYBN-UHFFFAOYSA-N 0.000 claims 1
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| GB9720061D0 (en) | 1997-09-19 | 1997-11-19 | Crosfield Joseph & Sons | Metal compounds as phosphate binders |
| MY157620A (en) | 2006-01-31 | 2016-06-30 | Cytochroma Dev Inc | A granular material of a solid water-soluble mixed metal compound capable of binding phosphate |
| GB0714670D0 (en) | 2007-07-27 | 2007-09-05 | Ineos Healthcare Ltd | Use |
| GB0720220D0 (en) | 2007-10-16 | 2007-11-28 | Ineos Healthcare Ltd | Compound |
| TWI592159B (zh) | 2007-11-16 | 2017-07-21 | 威佛（國際）股份有限公司 | 藥學組成物 |
| JP2009292119A (ja) | 2008-06-09 | 2009-12-17 | Alps Electric Co Ltd | サーマルヘッド |
| WO2009150232A2 (en) * | 2008-06-13 | 2009-12-17 | Novartis Ag | Manufacture process for the preparation of an iron containing phosphate adsorbent |
| GB0814326D0 (en) * | 2008-08-05 | 2008-09-10 | Medical Res Council | Phosphate binding materials and their uses |
| CN102573807A (zh) | 2009-07-21 | 2012-07-11 | 凯克斯生物制药公司 | 柠檬酸铁剂型 |
| GB0913525D0 (en) | 2009-08-03 | 2009-09-16 | Ineos Healthcare Ltd | Method |
| GB201001779D0 (en) | 2010-02-04 | 2010-03-24 | Ineos Healthcare Ltd | Composition |
| DE102011112898A1 (de) | 2011-09-08 | 2013-03-14 | Charité - Universitätsmedizin Berlin | Nanopartikuläres Phosphatadsorbens basierend auf Maghämit oder Maghämit/Magnetit, dessen Herstellung und Verwendungen |
| CA2849926C (en) * | 2011-10-13 | 2020-07-21 | Vidasym, Inc. | Iron-fiber composition, preparation and uses thereof |
| RU2496722C1 (ru) * | 2012-04-10 | 2013-10-27 | Леонид Асхатович Мазитов | Способ очистки сточной воды от фосфатов |
| CN109497565B (zh) | 2013-03-08 | 2021-10-26 | 上海礼邦医药科技有限公司 | 金属离子-功能性纤维组分络合物组合物、其制备及用途 |
| HK1216513A1 (zh) * | 2013-03-15 | 2016-11-18 | 阿普雷奇亚制药有限责任公司 | 包含左乙拉西坦的快速分散劑型 |
| US9339489B2 (en) * | 2013-03-15 | 2016-05-17 | Aprecia Pharmaceuticals Company | Rapid disperse dosage form containing levetiracetam |
| WO2015078900A1 (en) | 2013-11-27 | 2015-06-04 | Vifor (International) Ag | Pharmaceutical composition, comprising phosphate binder particles |
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2007
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| MX2009006307A (es) | 2009-06-23 |
| ECSP099410A (es) | 2009-07-31 |
| HK1133248A1 (en) | 2010-03-19 |
| JP2008150375A (ja) | 2008-07-03 |
| MA30993B1 (fr) | 2009-12-01 |
| NO20092632L (no) | 2009-07-14 |
| WO2008071747A1 (en) | 2008-06-19 |
| SI2319804T1 (sl) | 2015-01-30 |
| PT2319804E (pt) | 2014-11-24 |
| CA2671828C (en) | 2012-06-19 |
| US8252310B2 (en) | 2012-08-28 |
| IL198548A0 (en) | 2010-02-17 |
| TWI465239B (zh) | 2014-12-21 |
| TW200831115A (en) | 2008-08-01 |
| AU2007331482A1 (en) | 2008-06-19 |
| CA2671828A1 (en) | 2008-06-19 |
| JP5456969B2 (ja) | 2014-04-02 |
| NO342285B1 (no) | 2018-04-30 |
| CL2007003606A1 (es) | 2008-07-18 |
| AU2007331482B2 (en) | 2011-04-21 |
| US20120126440A1 (en) | 2012-05-24 |
| PE20081381A1 (es) | 2008-11-12 |
| US20080145410A1 (en) | 2008-06-19 |
| AR064301A1 (es) | 2009-03-25 |
| ES2526171T3 (es) | 2015-01-07 |
| MY151047A (en) | 2014-03-31 |
| TN2009000214A1 (en) | 2010-10-18 |
| NZ576672A (en) | 2012-02-24 |
| RU2009126614A (ru) | 2011-01-20 |
| RU2447933C2 (ru) | 2012-04-20 |
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