CA2663596A1 - Device and method for destruction of cancer cells - Google Patents

Device and method for destruction of cancer cells Download PDF

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Publication number
CA2663596A1
CA2663596A1 CA002663596A CA2663596A CA2663596A1 CA 2663596 A1 CA2663596 A1 CA 2663596A1 CA 002663596 A CA002663596 A CA 002663596A CA 2663596 A CA2663596 A CA 2663596A CA 2663596 A1 CA2663596 A1 CA 2663596A1
Authority
CA
Canada
Prior art keywords
target tissue
electrode
electrodes
ablation
cancerous cells
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002663596A
Other languages
English (en)
French (fr)
Inventor
Larry Azure
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
LAZURE TECHNOLOGIES LLC
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2663596A1 publication Critical patent/CA2663596A1/en
Abandoned legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B18/1477—Needle-like probes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B18/1492—Probes or electrodes therefor having a flexible, catheter-like structure, e.g. for heart ablation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N1/00—Electrotherapy; Circuits therefor
    • A61N1/02—Details
    • A61N1/04—Electrodes
    • A61N1/06—Electrodes for high-frequency therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00571—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
    • A61B2018/00577—Ablation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B2018/1405—Electrodes having a specific shape
    • A61B2018/1407—Loop
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B2018/1405—Electrodes having a specific shape
    • A61B2018/1425—Needle
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B2018/1405—Electrodes having a specific shape
    • A61B2018/1425—Needle
    • A61B2018/143—Needle multiple needles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B2018/1475—Electrodes retractable in or deployable from a housing

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Otolaryngology (AREA)
  • Molecular Biology (AREA)
  • Medical Informatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physics & Mathematics (AREA)
  • Plasma & Fusion (AREA)
  • Radiology & Medical Imaging (AREA)
  • Cardiology (AREA)
  • Surgical Instruments (AREA)
  • Electrotherapy Devices (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA002663596A 2006-09-14 2007-09-14 Device and method for destruction of cancer cells Abandoned CA2663596A1 (en)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US82566006P 2006-09-14 2006-09-14
US60/825,660 2006-09-14
US86348406P 2006-10-30 2006-10-30
US60/863,484 2006-10-30
PCT/US2007/078562 WO2008034103A2 (en) 2006-09-14 2007-09-14 Device and method for destruction of cancer cells

Publications (1)

Publication Number Publication Date
CA2663596A1 true CA2663596A1 (en) 2008-03-20

Family

ID=39184631

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002663596A Abandoned CA2663596A1 (en) 2006-09-14 2007-09-14 Device and method for destruction of cancer cells

Country Status (6)

Country Link
US (6) US8109926B2 (enExample)
EP (1) EP2068739A4 (enExample)
JP (1) JP5457183B2 (enExample)
CN (1) CN101553180B (enExample)
CA (1) CA2663596A1 (enExample)
WO (3) WO2008034103A2 (enExample)

Families Citing this family (221)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040215235A1 (en) 1999-11-16 2004-10-28 Barrx, Inc. Methods and systems for determining physiologic characteristics for treatment of the esophagus
AU2003299471A1 (en) 2002-05-07 2004-05-13 Kai Kroll Method and device for treating concer with electrical therapy in conjunction with chemotherapeutic agents and radiation therapy
US9655676B2 (en) 2003-05-16 2017-05-23 Trod Medical Method of percutaneous localized or focal treatment of prostate lesions using radio frequency
US20050171574A1 (en) 2003-12-24 2005-08-04 The Regents Of The University Of California Electroporation to interrupt blood flow
WO2007100727A2 (en) * 2006-02-24 2007-09-07 Eastern Virginia Medical School Nanosecond pulsed electric fields cause melanomas to self-destruct
US20080015574A1 (en) * 2006-03-31 2008-01-17 Karpiel John A Electrosurgical cutting device
CN101553180B (zh) 2006-09-14 2013-08-07 拉热尔技术有限公司 用于破坏癌细胞的装置
US7655004B2 (en) 2007-02-15 2010-02-02 Ethicon Endo-Surgery, Inc. Electroporation ablation apparatus, system, and method
US8641711B2 (en) * 2007-05-04 2014-02-04 Covidien Lp Method and apparatus for gastrointestinal tract ablation for treatment of obesity
US8784338B2 (en) 2007-06-22 2014-07-22 Covidien Lp Electrical means to normalize ablational energy transmission to a luminal tissue surface of varying size
CA2692669A1 (en) 2007-07-06 2009-01-15 Barrx Medical, Inc. Ablation in the gastrointestinal tract to achieve hemostasis and eradicate lesions with a propensity for bleeding
WO2009009443A1 (en) 2007-07-06 2009-01-15 Barrx Medical, Inc. Method and apparatus for gastrointestinal tract ablation to achieve loss of persistent and/or recurrent excess body weight following a weight-loss operation
US8273012B2 (en) 2007-07-30 2012-09-25 Tyco Healthcare Group, Lp Cleaning device and methods
US8646460B2 (en) * 2007-07-30 2014-02-11 Covidien Lp Cleaning device and methods
US8568410B2 (en) 2007-08-31 2013-10-29 Ethicon Endo-Surgery, Inc. Electrical ablation surgical instruments
US8579897B2 (en) * 2007-11-21 2013-11-12 Ethicon Endo-Surgery, Inc. Bipolar forceps
US8262655B2 (en) 2007-11-21 2012-09-11 Ethicon Endo-Surgery, Inc. Bipolar forceps
US20090062788A1 (en) * 2007-08-31 2009-03-05 Long Gary L Electrical ablation surgical instruments
WO2009036459A1 (en) * 2007-09-14 2009-03-19 Lazure Technologies, Llc Multi-tine probe and treatment by activation of opposing tines
CN105232148A (zh) * 2007-09-14 2016-01-13 拉热尔技术有限公司 前列腺癌消融
US20090112059A1 (en) 2007-10-31 2009-04-30 Nobis Rudolph H Apparatus and methods for closing a gastrotomy
US8480657B2 (en) * 2007-10-31 2013-07-09 Ethicon Endo-Surgery, Inc. Detachable distal overtube section and methods for forming a sealable opening in the wall of an organ
US8262680B2 (en) * 2008-03-10 2012-09-11 Ethicon Endo-Surgery, Inc. Anastomotic device
US10702326B2 (en) 2011-07-15 2020-07-07 Virginia Tech Intellectual Properties, Inc. Device and method for electroporation based treatment of stenosis of a tubular body part
EP2280741A4 (en) 2008-04-29 2012-06-13 Virginia Tech Intell Prop IRREVERSIBLE ELECTROPORATION FOR THE PRODUCTION OF TISSUE OBJECTS
US10238447B2 (en) 2008-04-29 2019-03-26 Virginia Tech Intellectual Properties, Inc. System and method for ablating a tissue site by electroporation with real-time monitoring of treatment progress
US8992517B2 (en) 2008-04-29 2015-03-31 Virginia Tech Intellectual Properties Inc. Irreversible electroporation to treat aberrant cell masses
US9198733B2 (en) 2008-04-29 2015-12-01 Virginia Tech Intellectual Properties, Inc. Treatment planning for electroporation-based therapies
US10272178B2 (en) 2008-04-29 2019-04-30 Virginia Tech Intellectual Properties Inc. Methods for blood-brain barrier disruption using electrical energy
US9867652B2 (en) 2008-04-29 2018-01-16 Virginia Tech Intellectual Properties, Inc. Irreversible electroporation using tissue vasculature to treat aberrant cell masses or create tissue scaffolds
US20240173063A1 (en) * 2008-04-29 2024-05-30 Virginia Tech Intellectual Properties Inc. System and method for ablating a tissue site by electroporation with real-time monitoring of treatment progress
US10245098B2 (en) 2008-04-29 2019-04-02 Virginia Tech Intellectual Properties, Inc. Acute blood-brain barrier disruption using electrical energy based therapy
US10448989B2 (en) 2009-04-09 2019-10-22 Virginia Tech Intellectual Properties, Inc. High-frequency electroporation for cancer therapy
US20240008911A1 (en) * 2008-04-29 2024-01-11 Virginia Tech Intellectual Properties, Inc. Immunotherapeutic methods using electroporation
US11272979B2 (en) 2008-04-29 2022-03-15 Virginia Tech Intellectual Properties, Inc. System and method for estimating tissue heating of a target ablation zone for electrical-energy based therapies
US8926606B2 (en) * 2009-04-09 2015-01-06 Virginia Tech Intellectual Properties, Inc. Integration of very short electric pulses for minimally to noninvasive electroporation
US10117707B2 (en) 2008-04-29 2018-11-06 Virginia Tech Intellectual Properties, Inc. System and method for estimating tissue heating of a target ablation zone for electrical-energy based therapies
US11254926B2 (en) 2008-04-29 2022-02-22 Virginia Tech Intellectual Properties, Inc. Devices and methods for high frequency electroporation
US9283051B2 (en) 2008-04-29 2016-03-15 Virginia Tech Intellectual Properties, Inc. System and method for estimating a treatment volume for administering electrical-energy based therapies
US12697172B2 (en) 2008-04-29 2026-08-04 Virginia Tech Intellectual Properties, Inc. System and method for estimating a treatment volume for administering electrical-energy based therapies
US20090281477A1 (en) * 2008-05-09 2009-11-12 Angiodynamics, Inc. Electroporation device and method
JP5602132B2 (ja) 2008-05-16 2014-10-08 トロッド メディカル 経皮及び腹腔鏡の手術器具
US8679003B2 (en) 2008-05-30 2014-03-25 Ethicon Endo-Surgery, Inc. Surgical device and endoscope including same
US8317806B2 (en) 2008-05-30 2012-11-27 Ethicon Endo-Surgery, Inc. Endoscopic suturing tension controlling and indication devices
US8771260B2 (en) 2008-05-30 2014-07-08 Ethicon Endo-Surgery, Inc. Actuating and articulating surgical device
US8403926B2 (en) 2008-06-05 2013-03-26 Ethicon Endo-Surgery, Inc. Manually articulating devices
US8361112B2 (en) 2008-06-27 2013-01-29 Ethicon Endo-Surgery, Inc. Surgical suture arrangement
US20100010294A1 (en) * 2008-07-10 2010-01-14 Ethicon Endo-Surgery, Inc. Temporarily positionable medical devices
US8262563B2 (en) 2008-07-14 2012-09-11 Ethicon Endo-Surgery, Inc. Endoscopic translumenal articulatable steerable overtube
US8888792B2 (en) 2008-07-14 2014-11-18 Ethicon Endo-Surgery, Inc. Tissue apposition clip application devices and methods
US8211125B2 (en) * 2008-08-15 2012-07-03 Ethicon Endo-Surgery, Inc. Sterile appliance delivery device for endoscopic procedures
US10736689B2 (en) 2008-08-20 2020-08-11 Prostacare Pty Ltd Low-corrosion electrode for treating tissue
EP2326273B1 (en) * 2008-08-20 2021-11-24 Prostacare Pty Ltd System including a catheter and deployable electrodes for the non-thermal ablation of tissue
US8529563B2 (en) * 2008-08-25 2013-09-10 Ethicon Endo-Surgery, Inc. Electrical ablation devices
US8241204B2 (en) 2008-08-29 2012-08-14 Ethicon Endo-Surgery, Inc. Articulating end cap
US8480689B2 (en) * 2008-09-02 2013-07-09 Ethicon Endo-Surgery, Inc. Suturing device
US8409200B2 (en) 2008-09-03 2013-04-02 Ethicon Endo-Surgery, Inc. Surgical grasping device
US8114119B2 (en) 2008-09-09 2012-02-14 Ethicon Endo-Surgery, Inc. Surgical grasping device
US20100100093A1 (en) * 2008-09-16 2010-04-22 Lazure Technologies, Llc. System and method for controlled tissue heating for destruction of cancerous cells
US8337394B2 (en) 2008-10-01 2012-12-25 Ethicon Endo-Surgery, Inc. Overtube with expandable tip
US20100106063A1 (en) * 2008-10-29 2010-04-29 Cabochon Aesthetics, Inc. Ultrasound Enhancing Target for Treating Subcutaneous Tissue
US8157834B2 (en) 2008-11-25 2012-04-17 Ethicon Endo-Surgery, Inc. Rotational coupling device for surgical instrument with flexible actuators
US20100152725A1 (en) * 2008-12-12 2010-06-17 Angiodynamics, Inc. Method and system for tissue treatment utilizing irreversible electroporation and thermal track coagulation
US20100168568A1 (en) * 2008-12-30 2010-07-01 St. Jude Medical, Atrial Fibrillation Division Inc. Combined Diagnostic and Therapeutic Device Using Aligned Energy Beams
US8828031B2 (en) 2009-01-12 2014-09-09 Ethicon Endo-Surgery, Inc. Apparatus for forming an anastomosis
US8361066B2 (en) 2009-01-12 2013-01-29 Ethicon Endo-Surgery, Inc. Electrical ablation devices
US9226772B2 (en) 2009-01-30 2016-01-05 Ethicon Endo-Surgery, Inc. Surgical device
US8252057B2 (en) 2009-01-30 2012-08-28 Ethicon Endo-Surgery, Inc. Surgical access device
WO2010093692A2 (en) * 2009-02-10 2010-08-19 Hobbs Eamonn P Irreversible electroporation and tissue regeneration
US8632534B2 (en) 2009-04-03 2014-01-21 Angiodynamics, Inc. Irreversible electroporation (IRE) for congestive obstructive pulmonary disease (COPD)
US11638603B2 (en) 2009-04-09 2023-05-02 Virginia Tech Intellectual Properties, Inc. Selective modulation of intracellular effects of cells using pulsed electric fields
US11382681B2 (en) 2009-04-09 2022-07-12 Virginia Tech Intellectual Properties, Inc. Device and methods for delivery of high frequency electrical pulses for non-thermal ablation
US8903488B2 (en) 2009-05-28 2014-12-02 Angiodynamics, Inc. System and method for synchronizing energy delivery to the cardiac rhythm
US9895189B2 (en) 2009-06-19 2018-02-20 Angiodynamics, Inc. Methods of sterilization and treating infection using irreversible electroporation
US20110098704A1 (en) 2009-10-28 2011-04-28 Ethicon Endo-Surgery, Inc. Electrical ablation devices
US8608652B2 (en) 2009-11-05 2013-12-17 Ethicon Endo-Surgery, Inc. Vaginal entry surgical devices, kit, system, and method
US20110112434A1 (en) * 2009-11-06 2011-05-12 Ethicon Endo-Surgery, Inc. Kits and procedures for natural orifice translumenal endoscopic surgery
US8353487B2 (en) * 2009-12-17 2013-01-15 Ethicon Endo-Surgery, Inc. User interface support devices for endoscopic surgical instruments
US8496574B2 (en) 2009-12-17 2013-07-30 Ethicon Endo-Surgery, Inc. Selectively positionable camera for surgical guide tube assembly
US8506564B2 (en) 2009-12-18 2013-08-13 Ethicon Endo-Surgery, Inc. Surgical instrument comprising an electrode
US9028483B2 (en) 2009-12-18 2015-05-12 Ethicon Endo-Surgery, Inc. Surgical instrument comprising an electrode
US20110190764A1 (en) * 2010-01-29 2011-08-04 Ethicon Endo-Surgery, Inc. Surgical instrument comprising an electrode
US9005198B2 (en) * 2010-01-29 2015-04-14 Ethicon Endo-Surgery, Inc. Surgical instrument comprising an electrode
US20110238057A1 (en) * 2010-02-16 2011-09-29 Angiodynamics, Inc. Dual Bracketed Energy Delivery Probe and Method of Use
US20110288545A1 (en) * 2010-04-22 2011-11-24 Old Dominion University Research Foundation Method and Device for Ablation of Cancer and Resistance to New Cancer Growth
US9526911B1 (en) * 2010-04-27 2016-12-27 Lazure Scientific, Inc. Immune mediated cancer cell destruction, systems and methods
WO2012051433A2 (en) 2010-10-13 2012-04-19 Angiodynamics, Inc. System and method for electrically ablating tissue of a patient
WO2012068580A1 (en) * 2010-11-19 2012-05-24 Intermountain Invention Management, Llc Devices for killing tumor cells and related systems and methods
US10092291B2 (en) 2011-01-25 2018-10-09 Ethicon Endo-Surgery, Inc. Surgical instrument with selectively rigidizable features
US9233241B2 (en) 2011-02-28 2016-01-12 Ethicon Endo-Surgery, Inc. Electrical ablation devices and methods
US9314620B2 (en) 2011-02-28 2016-04-19 Ethicon Endo-Surgery, Inc. Electrical ablation devices and methods
US9254169B2 (en) 2011-02-28 2016-02-09 Ethicon Endo-Surgery, Inc. Electrical ablation devices and methods
US9049987B2 (en) 2011-03-17 2015-06-09 Ethicon Endo-Surgery, Inc. Hand held surgical device for manipulating an internal magnet assembly within a patient
US10278774B2 (en) 2011-03-18 2019-05-07 Covidien Lp Selectively expandable operative element support structure and methods of use
EP2792323B1 (en) 2011-08-25 2017-10-04 Covidien LP Systems and devices for treatment of luminal tissue
US9078665B2 (en) 2011-09-28 2015-07-14 Angiodynamics, Inc. Multiple treatment zone ablation probe
AU2012323882A1 (en) 2011-10-15 2014-05-15 Diros Technology Inc. Method and apparatus for precisely controlling the size and shape of radiofrequency ablations
JP2015057080A (ja) * 2012-01-12 2015-03-26 テルモ株式会社 体内組織焼灼システム
US9414881B2 (en) 2012-02-08 2016-08-16 Angiodynamics, Inc. System and method for increasing a target zone for electrical ablation
US8986199B2 (en) 2012-02-17 2015-03-24 Ethicon Endo-Surgery, Inc. Apparatus and methods for cleaning the lens of an endoscope
US9314299B2 (en) 2012-03-21 2016-04-19 Biosense Webster (Israel) Ltd. Flower catheter for mapping and ablating veinous and other tubular locations
US9427255B2 (en) 2012-05-14 2016-08-30 Ethicon Endo-Surgery, Inc. Apparatus for introducing a steerable camera assembly into a patient
US9078662B2 (en) 2012-07-03 2015-07-14 Ethicon Endo-Surgery, Inc. Endoscopic cap electrode and method for using the same
US10537748B2 (en) 2012-07-23 2020-01-21 Koninklijke Philips N.V. Combined brachytherapy and electrochemotherapy catheters
US9545290B2 (en) 2012-07-30 2017-01-17 Ethicon Endo-Surgery, Inc. Needle probe guide
US10314649B2 (en) 2012-08-02 2019-06-11 Ethicon Endo-Surgery, Inc. Flexible expandable electrode and method of intraluminal delivery of pulsed power
US9572623B2 (en) 2012-08-02 2017-02-21 Ethicon Endo-Surgery, Inc. Reusable electrode and disposable sheath
US9044254B2 (en) * 2012-08-07 2015-06-02 Covidien Lp Microwave ablation catheter and method of utilizing the same
US9277957B2 (en) 2012-08-15 2016-03-08 Ethicon Endo-Surgery, Inc. Electrosurgical devices and methods
US9743975B2 (en) 2012-10-02 2017-08-29 Covidien Lp Thermal ablation probe for a medical device
US9888956B2 (en) 2013-01-22 2018-02-13 Angiodynamics, Inc. Integrated pump and generator device and method of use
US10098527B2 (en) 2013-02-27 2018-10-16 Ethidcon Endo-Surgery, Inc. System for performing a minimally invasive surgical procedure
US20140296843A1 (en) 2013-03-27 2014-10-02 Bnr Technology Development, Llc Apparatus and method for treating cancer cells and bacteria in mammals including humans
CA2914195C (en) 2013-06-03 2020-06-02 Nanoblate Corporation Methods and devices for stimulating an immune response using nanosecond pulsed electric fields
US10154869B2 (en) * 2013-08-02 2018-12-18 Gary M. Onik System and method for creating radio-frequency energy electrical membrane breakdown for tissue ablation
US10709491B2 (en) 2013-08-06 2020-07-14 Memorial Sloan-Kettering Cancer Center System, method and computer-accessible medium for in-vivo tissue ablation and/or damage
EP4000685B1 (en) 2013-11-14 2024-06-12 RM2 Technology LLC Apparatuses for tissue ablation using electrolysis and permeabilization
FI3077041T3 (fi) * 2013-12-05 2024-10-16 Rfemb Holdings Llc Syövän immunoterapia radiotaajuisella sähköisellä solukalvon hajotuksella (rf-emb)
CN103892920A (zh) * 2014-04-03 2014-07-02 张道福 一种神经外科手术引导工具
EP3143124B1 (en) 2014-05-12 2025-01-22 Virginia Tech Intellectual Properties, Inc. Selective modulation of intracellular effects of cells using pulsed electric fields
WO2016018754A1 (en) * 2014-07-28 2016-02-04 Boston Scientific Scimed, Inc. Multiple lead electrode probe for controlled tissue ablation
GB201414529D0 (en) * 2014-08-15 2014-10-01 Asalus Medical Instr Ltd A surgical instrument
US12114911B2 (en) 2014-08-28 2024-10-15 Angiodynamics, Inc. System and method for ablating a tissue site by electroporation with real-time pulse monitoring
US9724155B2 (en) 2014-12-01 2017-08-08 Pulse Biosciences, Inc. Nanoelectroablation control and vaccination
WO2016100325A1 (en) 2014-12-15 2016-06-23 Virginia Tech Intellectual Properties, Inc. Devices, systems, and methods for real-time monitoring of electrophysical effects during tissue treatment
US10299858B2 (en) 2014-12-23 2019-05-28 Cook Medical Technologies Llc Variable thickness electrosurgical snare
CA2975123A1 (en) 2015-01-30 2016-08-04 Rfemb Holdings, Llc Radio frequency electrical membrane breakdown for the treatment of high risk and recurrent prostate cancer, unresectable pancreatic cancer, tumors of the breast, melanoma or other skin malignancies, sarcoma, soft tissue tumors, ductal carcinoma, neoplasia, and intra and extra luminal abnormal tissue
CA2975931A1 (en) * 2015-02-04 2016-08-11 Rfemb Holdings, Llc Radio-frequency electrical membrane breakdown for the treatment of adipose tissue and removal of unwanted body fat
US20180028267A1 (en) * 2015-02-04 2018-02-01 Rfemb Holdings, Llc Radio-frequency electrical membrane breakdown for the treatment of benign prostatic hyperplasia
US20180021084A1 (en) * 2015-02-04 2018-01-25 Rfemb Holdings, Llc Radio-frequency electrical membrane breakdown for reducing restenosis
CA2975888A1 (en) * 2015-02-06 2016-08-11 Rfemb Holdings, Llc Radio-frequency electrical membrane breakdown for the treatment of cardiac rhythm disorders and for renal neuromodulation
US9775673B2 (en) * 2015-03-26 2017-10-03 Garner B. Meads, JR. Nasal coagulation suction device and methods
US10806512B2 (en) * 2015-03-26 2020-10-20 Garner B. Meads, JR. Nasal coagulation suction device and methods
EP3288471A1 (en) * 2015-05-01 2018-03-07 Inter Science GmbH Methods, systems, and apparatuses for tissue ablation using pulse shape designs
CN106308929A (zh) * 2015-06-30 2017-01-11 四川锦江电子科技有限公司 一种极间放电的消融装置
CN114209420A (zh) 2015-10-07 2022-03-22 梅约医学教育与研究基金会 用于肥胖症或糖尿病治疗的电穿孔
CA3011460A1 (en) 2016-01-15 2017-07-20 Rfemb Holdings, Llc Immunologic treatment of cancer
US10874451B2 (en) 2016-02-29 2020-12-29 Pulse Biosciences, Inc. High-voltage analog circuit pulser and pulse generator discharge circuit
US10548665B2 (en) * 2016-02-29 2020-02-04 Pulse Biosciences, Inc. High-voltage analog circuit pulser with feedback control
US10252050B2 (en) 2016-05-16 2019-04-09 Pulse Biosciences, Inc. Pulse applicator
DK3474760T3 (da) 2016-06-27 2023-03-20 Galvanize Therapeutics Inc Generator og et kateter med en elektrode til at behandle en lungepassage
US12403305B2 (en) 2016-06-27 2025-09-02 Galvanize Therapeutics, Inc. Immunostimulation in the treatment of viral infection
CN106236248B (zh) * 2016-08-30 2019-11-12 苏州涵轩信息科技有限公司 一种射频消融设备、系统和方法
US10543357B2 (en) 2016-09-19 2020-01-28 Pulse Biosciences, Inc. High voltage connectors for pulse generators
DE112016007183T5 (de) * 2016-09-28 2019-07-04 Olympus Corporation Behandlungswerkzeug
US10905492B2 (en) 2016-11-17 2021-02-02 Angiodynamics, Inc. Techniques for irreversible electroporation using a single-pole tine-style internal device communicating with an external surface electrode
US10946193B2 (en) 2017-02-28 2021-03-16 Pulse Biosciences, Inc. Pulse generator with independent panel triggering
CN107260300A (zh) * 2017-07-20 2017-10-20 常州朗合医疗器械有限公司 射频消融导管及系统
US10857347B2 (en) 2017-09-19 2020-12-08 Pulse Biosciences, Inc. Treatment instrument and high-voltage connectors for robotic surgical system
US11648047B2 (en) 2017-10-06 2023-05-16 Vive Scientific, Llc System and method to treat obstructive sleep apnea
US12649056B2 (en) 2017-10-23 2026-06-09 Cardiac Pacemakers, Inc. Medical devices for treatment of cancer with electric fields
US12403306B2 (en) 2017-10-23 2025-09-02 Cardiac Pacemakers, Inc. Electric field shaping leads for treatment of cancer
US20190117971A1 (en) * 2017-10-23 2019-04-25 Cardiac Pacemakers, Inc. Volume-filling leads for treatment of cancer with electric fields
US11338135B2 (en) * 2017-10-23 2022-05-24 Cardiac Pacemakers, Inc. Medical devices for cancer therapy with electric field shaping elements
US11045648B2 (en) 2017-11-14 2021-06-29 Boston Scientific Scimed, Inc. Irreversible electroporation through a combination of substance injection and electrical field application
US11457975B2 (en) 2017-11-27 2022-10-04 Prostacare Pty Ltd Apparatus and a method for the treatment of a prostatic disease
US11607537B2 (en) 2017-12-05 2023-03-21 Virginia Tech Intellectual Properties, Inc. Method for treating neurological disorders, including tumors, with electroporation
EP4552592A3 (en) 2017-12-26 2025-06-18 Galvanize Therapeutics, Inc. Optimization of energy delivery for various applications
JP7045464B2 (ja) * 2018-01-23 2022-03-31 ボストン サイエンティフィック サイムド,インコーポレイテッド 腫瘍アブレーションのための強化ニードルアレイと治療方法
EP3749191A1 (en) * 2018-02-06 2020-12-16 Biosense Webster (Israel) Ltd Medical probe with staggered microelectrode configuration
WO2019168949A1 (en) 2018-02-28 2019-09-06 Prostacare Pty Ltd System for managing high impedance changes in a non-thermal ablation system for bph
US12390262B2 (en) 2018-03-13 2025-08-19 Virginia Tech Intellectual Properties, Inc. Treatment planning system for immunotherapy enhancement via non-thermal ablation
US11311329B2 (en) 2018-03-13 2022-04-26 Virginia Tech Intellectual Properties, Inc. Treatment planning for immunotherapy based treatments using non-thermal ablation techniques
US11925405B2 (en) 2018-03-13 2024-03-12 Virginia Tech Intellectual Properties, Inc. Treatment planning system for immunotherapy enhancement via non-thermal ablation
RU2723883C2 (ru) * 2018-07-17 2020-06-18 Николай Васильевич Цугленок Способ инициации гибели опухолевых клеток аскорбиновой и гидрозидом 3-аминофталевой кислотами и ВЧ- и СВЧ-энергией волнового излучения
RU2739254C2 (ru) * 2018-07-17 2020-12-22 Николай Васильевич Цугленок Способ инициации гибели опухолевых клеток янтарной и 3-аминофталевой кислотами и ВЧ- и СВЧ-энергией волнового излучения
EP3846724A4 (en) 2018-09-04 2022-05-11 Inter Science GmbH METHODS, SYSTEMS AND DEVICES FOR TISSUE ABLATION USING A MODULATED EXPONENTIAL OUTLET PULSE
US20200100834A1 (en) * 2018-09-27 2020-04-02 Covidien Lp Energy-based tissue specimen removal
US11135004B2 (en) * 2018-12-24 2021-10-05 Industrial Technology Research Institute Ablation device
SG11202107944VA (en) * 2019-01-23 2021-08-30 Ablation Gen 2 Pty Ltd Devices and methods for ablating tissue
US11571569B2 (en) 2019-02-15 2023-02-07 Pulse Biosciences, Inc. High-voltage catheters for sub-microsecond pulsing
EP3937810A1 (en) 2019-03-15 2022-01-19 Boston Scientific Scimed, Inc. Spatially multiplexed waveform for selective cell ablation
WO2020190693A1 (en) 2019-03-15 2020-09-24 Boston Scientific Scimed, Inc. Waveform generator and control for selective cell ablation
CN118948428A (zh) 2019-03-15 2024-11-15 波士顿科学国际有限公司 用于选择性细胞消融的时间多路复用波形
CN114007535A (zh) * 2019-04-18 2022-02-01 盖乐世公司 用于治疗异常组织的装置、系统和方法
JP7593942B2 (ja) 2019-04-22 2024-12-03 ボストン サイエンティフィック サイムド,インコーポレイテッド 癌治療のための電気刺激機器
CN113766949B (zh) 2019-04-22 2025-04-08 波士顿科学国际有限公司 用于施用电刺激以治疗癌症的系统
US12109412B2 (en) 2019-04-22 2024-10-08 Boston Scientific Scimed, Inc. Combination electrical and chemotherapeutic treatment of cancer
US11607542B2 (en) 2019-04-23 2023-03-21 Boston Scientific Scimed, Inc. Electrical stimulation for cancer treatment with internal and external electrodes
JP2022529374A (ja) * 2019-04-23 2022-06-21 ボストン サイエンティフィック サイムド,インコーポレイテッド がん治療のための電気刺激用電極
WO2020219521A1 (en) 2019-04-23 2020-10-29 Boston Scientific Scimed, Inc. Electrical stimulation with thermal treatment or thermal monitoring
CN118648968B (zh) 2019-05-09 2026-06-19 捷锐士阿希迈公司(以奥林巴斯美国外科技术名义) 外科发生器和方法
US10667855B1 (en) 2019-05-10 2020-06-02 Trod Medical Us, Llc Dual coil ablation devices
CN110151300A (zh) * 2019-05-17 2019-08-23 杭州睿笛生物科技有限公司 一种可协同给药的电脉冲消融装置
CN110151306A (zh) * 2019-05-17 2019-08-23 杭州睿笛生物科技有限公司 一种电脉冲平行电极
WO2020243389A1 (en) * 2019-05-29 2020-12-03 Sirona Medical Technologies, Inc. Cardiac electrical mapping and ablation
US11950835B2 (en) 2019-06-28 2024-04-09 Virginia Tech Intellectual Properties, Inc. Cycled pulsing to mitigate thermal damage for multi-electrode irreversible electroporation therapy
CA3147592A1 (en) 2019-07-16 2021-01-21 Galary, Inc. Treatment of the reproductive tract with pulsed electric fields
US12214189B2 (en) 2019-07-24 2025-02-04 Virginia Tech Intellectual Properties, Inc. Fourier analysis spectroscopy for monitoring tissue impedance changes and treatment outcome during electroporation-based-therapies
CN110755148B (zh) * 2019-09-20 2020-09-08 姚陈果 脉冲电场肿瘤消融参数优化系统
DE102020124443A1 (de) * 2019-09-26 2021-04-01 Gyrus Acmi, Inc. D/B/A Olympus Surgical Technologies America Vorrichtungen, systeme und verfahren zum transportieren von hilfsmitteln durch einen engen durchgang in einem körper
CN114945338A (zh) 2019-10-15 2022-08-26 波士顿科学国际有限公司 用于消融系统的控制系统和用户界面
CN114786605B (zh) 2019-10-21 2026-07-17 英杜基奈克斯公司 用于十二指肠脉冲电场治疗的装置、系统和方法
CN110840552B (zh) * 2019-12-10 2025-01-28 杭州睿笛生物科技有限公司 一种治疗房颤的电脉冲消融系统及其使用方法
CN110960314B (zh) * 2019-12-31 2021-06-15 杭州堃博生物科技有限公司 检测机构、射频消融导管及射频消融系统
US11883655B2 (en) 2020-02-24 2024-01-30 Boston Scientific Scimed, Inc. Systems and methods for treatment of pancreatic cancer
US11992260B2 (en) 2020-03-31 2024-05-28 Boston Scientific Scimed, Inc. Smart probe identification for ablation modalities
CN115348844A (zh) 2020-04-08 2022-11-15 盖能适治疗股份有限公司 脉冲电场波形操作和使用
WO2021216750A1 (en) * 2020-04-22 2021-10-28 Ne Scientific, Llc Interactive multi-probe ablation guidance system and method
US12171484B2 (en) * 2020-05-27 2024-12-24 Medtronic, Inc. Safety default return path for electric field therapy
CN111772782A (zh) * 2020-08-10 2020-10-16 湖南菁益医疗科技有限公司 一种电极及消融设备
US12016612B2 (en) 2020-08-19 2024-06-25 Acclarent, Inc. ENT ablation instrument with electrode loop
US12414684B2 (en) 2020-08-19 2025-09-16 Acclarent, Inc. ENT instrument with deformable guide having translatable imaging feature
WO2022070139A1 (en) * 2020-09-30 2022-04-07 Novocure Gmbh Implantable arrays for providing tumor treating fields
TWI869971B (zh) * 2020-10-16 2025-01-11 瑞士商諾沃庫勒有限責任公司 藉由使用TTFields活化STING途徑以降低癌細胞生存力的方法
TWI815047B (zh) * 2020-10-16 2023-09-11 瑞士商諾沃庫勒有限責任公司 藉由使用TTFields活化STING途徑以降低癌細胞生存力的方法
US12485279B2 (en) 2020-11-25 2025-12-02 Virginia Tech Intellectual Properties, Inc. Methods for modulating temporal infrastructure of pulsed electric fields
CN112641503A (zh) * 2020-12-25 2021-04-13 山西白求恩医院(山西医学科学院) 一种肿瘤射频消融装置
CN112933407B (zh) * 2021-01-28 2024-07-23 杭州维纳安可医疗科技有限责任公司 电极结构、电极贴片及细胞分裂抑制装置
US12484951B2 (en) 2021-02-22 2025-12-02 Japan Lifeline Co., Ltd. Power supply device and ablation system
CR20230475A (es) 2021-04-07 2024-01-19 Btl Medical Dev A S Dispositivo y método de ablación de campo pulsado
PL4366637T3 (pl) 2021-07-06 2025-11-03 Btl Medical Development A.S. Urządzenie do ablacji pulsacyjnym polem elektrycznym
WO2023097113A1 (en) 2021-11-29 2023-06-01 Boston Scientific Scimed, Inc. Bipolar needle with adjustable electrode for geometrically controlled thermal ablation of biological tissue
CN114652434B (zh) * 2022-02-16 2023-09-26 电子科技大学 一种基于mems微针束的多窗口微波消融方法及其装置
CN115177357B (zh) * 2022-07-12 2026-04-17 深圳迈微医疗科技有限公司 双模态组织消融装置
CN115317789A (zh) * 2022-07-28 2022-11-11 上海美生医疗器械有限公司 具有多个电场发生触点的电极装置
CN115253067A (zh) * 2022-07-28 2022-11-01 上海美生医疗器械有限公司 植入式电极装置的电极部
WO2024075034A1 (en) 2022-10-05 2024-04-11 Btl Medical Technologies S.R.O. Pulsed field ablation device and method
CN115779273A (zh) * 2022-11-03 2023-03-14 赛福凯尔(绍兴)医疗科技有限公司 电场能量聚焦的发射装置及方法
CN116636922B (zh) * 2023-05-12 2024-05-03 心诺普医疗技术(北京)有限公司 磁感应热消融球囊导管及消融方法
CN118058828B (zh) * 2024-04-17 2024-06-18 天津市鹰泰利安康医疗科技有限责任公司 一种双模态复合胰腺癌肿瘤的消融方法及系统

Family Cites Families (98)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3991770A (en) 1974-01-24 1976-11-16 Leveen Harry H Method for treating benign and malignant tumors utilizing radio frequency, electromagnetic radiation
US4016886A (en) * 1974-11-26 1977-04-12 The United States Of America As Represented By The United States Energy Research And Development Administration Method for localizing heating in tumor tissue
US4346715A (en) 1978-07-12 1982-08-31 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Hyperthermia heating apparatus
US4448198A (en) * 1979-06-19 1984-05-15 Bsd Medical Corporation Invasive hyperthermia apparatus and method
US5370675A (en) 1992-08-12 1994-12-06 Vidamed, Inc. Medical probe device and method
CA1244889A (en) * 1983-01-24 1988-11-15 Kureha Chemical Ind Co Ltd HYPERTHERMIA DEVICE
WO1985002779A1 (en) 1983-12-27 1985-07-04 Board Of Trustees Of Leland Stanford Junior Univer Catheter for treatment of tumors and method for using same
US4723161A (en) * 1985-03-20 1988-02-02 Nec Corporation Method and arrangement of coding digital image signals utilizing interframe correlation
FR2582947B1 (fr) * 1985-06-07 1988-05-13 Cgr Mev Dispositif de traitement par hyperthermie
US4860752A (en) 1988-02-18 1989-08-29 Bsd Medical Corporation Invasive microwave array with destructive and coherent phase
US7549424B2 (en) * 1991-10-18 2009-06-23 Pro Surg, Inc. Method and apparatus for tissue treatment with laser and electromagnetic radiation
US6296638B1 (en) * 1993-05-10 2001-10-02 Arthrocare Corporation Systems for tissue ablation and aspiration
US5681282A (en) 1992-01-07 1997-10-28 Arthrocare Corporation Methods and apparatus for ablation of luminal tissues
US5370677A (en) * 1992-03-06 1994-12-06 Urologix, Inc. Gamma matched, helical dipole microwave antenna with tubular-shaped capacitor
US5277201A (en) 1992-05-01 1994-01-11 Vesta Medical, Inc. Endometrial ablation apparatus and method
US6749604B1 (en) * 1993-05-10 2004-06-15 Arthrocare Corporation Electrosurgical instrument with axially-spaced electrodes
CA2164860C (en) 1993-06-10 2005-09-06 Mir A. Imran Transurethral radio frequency ablation apparatus
US5807395A (en) 1993-08-27 1998-09-15 Medtronic, Inc. Method and apparatus for RF ablation and hyperthermia
US5472441A (en) 1993-11-08 1995-12-05 Zomed International Device for treating cancer and non-malignant tumors and methods
US5536267A (en) * 1993-11-08 1996-07-16 Zomed International Multiple electrode ablation apparatus
US5599345A (en) 1993-11-08 1997-02-04 Zomed International, Inc. RF treatment apparatus
US6071280A (en) * 1993-11-08 2000-06-06 Rita Medical Systems, Inc. Multiple electrode ablation apparatus
US6056744A (en) * 1994-06-24 2000-05-02 Conway Stuart Medical, Inc. Sphincter treatment apparatus
US5630426A (en) 1995-03-03 1997-05-20 Neovision Corporation Apparatus and method for characterization and treatment of tumors
US5868740A (en) 1995-03-24 1999-02-09 Board Of Regents-Univ Of Nebraska Method for volumetric tissue ablation
US6149620A (en) * 1995-11-22 2000-11-21 Arthrocare Corporation System and methods for electrosurgical tissue treatment in the presence of electrically conductive fluid
US6090105A (en) * 1995-08-15 2000-07-18 Rita Medical Systems, Inc. Multiple electrode ablation apparatus and method
US5810804A (en) * 1995-08-15 1998-09-22 Rita Medical Systems Multiple antenna ablation apparatus and method with cooling element
US6235023B1 (en) * 1995-08-15 2001-05-22 Rita Medical Systems, Inc. Cell necrosis apparatus
US5863290A (en) * 1995-08-15 1999-01-26 Rita Medical Systems Multiple antenna ablation apparatus and method
US6080150A (en) * 1995-08-15 2000-06-27 Rita Medical Systems, Inc. Cell necrosis apparatus
US6246912B1 (en) * 1996-06-27 2001-06-12 Sherwood Services Ag Modulated high frequency tissue modification
US5993447A (en) * 1996-08-16 1999-11-30 United States Surgical Apparatus for thermal treatment of tissue
ES2353846T3 (es) 1997-04-11 2011-03-07 United States Surgical Corporation Aparato para ablación con rf y controlador del mismo.
US5792140A (en) 1997-05-15 1998-08-11 Irvine Biomedical, Inc. Catheter having cooled multiple-needle electrode
US6050992A (en) 1997-05-19 2000-04-18 Radiotherapeutics Corporation Apparatus and method for treating tissue with multiple electrodes
US6652515B1 (en) * 1997-07-08 2003-11-25 Atrionix, Inc. Tissue ablation device assembly and method for electrically isolating a pulmonary vein ostium from an atrial wall
US6517534B1 (en) 1998-02-11 2003-02-11 Cosman Company, Inc. Peri-urethral ablation
US6440127B2 (en) * 1998-02-11 2002-08-27 Cosman Company, Inc. Method for performing intraurethral radio-frequency urethral enlargement
US5968041A (en) 1998-04-02 1999-10-19 Vida Care, Inc. Directable thermal energy delivery apparatus
US7198635B2 (en) * 2000-10-17 2007-04-03 Asthmatx, Inc. Modification of airways by application of energy
US6136020A (en) 1998-06-26 2000-10-24 Faour; Ali M. Treatment for prostatitis and apparatus therefor
US6537272B2 (en) * 1998-07-07 2003-03-25 Medtronic, Inc. Apparatus and method for creating, maintaining, and controlling a virtual electrode used for the ablation of tissue
US6212433B1 (en) 1998-07-28 2001-04-03 Radiotherapeutics Corporation Method for treating tumors near the surface of an organ
WO2003024305A2 (en) * 2001-09-14 2003-03-27 Arthrocare Corporation Electrosurgical apparatus and methods for tissue treatment & removal
US6148236A (en) 1998-11-04 2000-11-14 Urologix, Inc. Cancer treatment system employing supplemented thermal therapy
US6666875B1 (en) 1999-03-05 2003-12-23 Olympus Optical Co., Ltd. Surgical apparatus permitting recharge of battery-driven surgical instrument in noncontact state
US6738663B2 (en) 1999-04-09 2004-05-18 Oncostim, A Minnesota Corporation Implantable device and method for the electrical treatment of cancer
US6939346B2 (en) * 1999-04-21 2005-09-06 Oratec Interventions, Inc. Method and apparatus for controlling a temperature-controlled probe
US7053063B2 (en) 1999-07-21 2006-05-30 The Regents Of The University Of California Controlled electroporation and mass transfer across cell membranes in tissue
AU1760001A (en) * 1999-11-10 2001-06-06 Quest Diagnostics Investments Incorporated Use of computationally derived protein structures of genetic polymorphisms in pharmacogenomics and clinical applications
US6853864B2 (en) 2000-02-02 2005-02-08 Catholic University Of America, The Use of electromagnetic fields in cancer and other therapies
EP2335776A1 (en) 2000-02-17 2011-06-22 Yoram Palti Method and apparatus for destroying dividing cells
US7136699B2 (en) 2002-10-02 2006-11-14 Standen, Ltd. Apparatus for destroying dividing cells
US7016725B2 (en) 2001-11-06 2006-03-21 Standen Ltd. Method and apparatus for destroying dividing cells
US6868289B2 (en) 2002-10-02 2005-03-15 Standen Ltd. Apparatus for treating a tumor or the like and articles incorporating the apparatus for treatment of the tumor
US7089054B2 (en) * 2002-10-02 2006-08-08 Standen Ltd. Apparatus and method for treating a tumor or the like
US7146210B2 (en) 2000-02-17 2006-12-05 Standen Ltd. Apparatus and method for optimizing tumor treatment efficiency by electric fields
US6944504B1 (en) 2000-02-23 2005-09-13 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Microwave medical treatment apparatus and method
WO2001074251A2 (en) * 2000-03-31 2001-10-11 Rita Medical Systems Inc. Tissue biopsy and treatment apparatus and method
US6477426B1 (en) * 2000-06-20 2002-11-05 Celsion Corporation System and method for heating the prostate gland to treat and prevent the growth and spread of prostate tumors
AU2001279026B2 (en) * 2000-07-25 2005-12-22 Angiodynamics, Inc. Apparatus for detecting and treating tumors using localized impedance measurement
US8251986B2 (en) * 2000-08-17 2012-08-28 Angiodynamics, Inc. Method of destroying tissue cells by eletroporation
US6892099B2 (en) * 2001-02-08 2005-05-10 Minnesota Medical Physics, Llc Apparatus and method for reducing subcutaneous fat deposits, virtual face lift and body sculpturing by electroporation
US6682555B2 (en) 2000-11-13 2004-01-27 Wit Ip Corporation Methods for treating the prostate and inhibiting obstruction of the prostatic urethra using biodegradable stents
US6866624B2 (en) 2000-12-08 2005-03-15 Medtronic Ave,Inc. Apparatus and method for treatment of malignant tumors
US20020087151A1 (en) 2000-12-29 2002-07-04 Afx, Inc. Tissue ablation apparatus with a sliding ablation instrument and method
US6743226B2 (en) 2001-02-09 2004-06-01 Cosman Company, Inc. Adjustable trans-urethral radio-frequency ablation
JP4346826B2 (ja) * 2001-02-28 2009-10-21 瑞穂医科工業株式会社 携帯型電気手術器、それを備えた携帯型電気手術器システムおよび携帯型電気手術器の制御方法
WO2002089686A1 (en) 2001-05-10 2002-11-14 Rita Medical Systems, Inc. Rf tissue ablation apparatus and method
US7135029B2 (en) 2001-06-29 2006-11-14 Makin Inder Raj S Ultrasonic surgical instrument for intracorporeal sonodynamic therapy
US6994706B2 (en) * 2001-08-13 2006-02-07 Minnesota Medical Physics, Llc Apparatus and method for treatment of benign prostatic hyperplasia
US6835864B2 (en) * 2001-09-05 2004-12-28 Aaron John Luck Method and device for treating minor wounds
ATE320767T1 (de) * 2001-09-28 2006-04-15 Rita Medical Systems Inc Impedanzgesteuerte vorrichtung zur ablation von gewebe
AU2002357166A1 (en) * 2001-12-12 2003-06-23 Tissuelink Medical, Inc. Fluid-assisted medical devices, systems and methods
US6993394B2 (en) 2002-01-18 2006-01-31 Calfacion Corporation System method and apparatus for localized heating of tissue
US6850804B2 (en) * 2002-01-18 2005-02-01 Calfacior Corporation System method and apparatus for localized heating of tissue
US6895282B2 (en) * 2002-10-04 2005-05-17 Boston Scientific Scimed, Inc. Induction heating for the delivery of thermal therapy
DE60309744T2 (de) 2002-11-27 2007-09-20 Medical Device Innovations Ltd., Halton Gewebsablationsgerät
US7238182B2 (en) * 2003-04-25 2007-07-03 Medtronic, Inc. Device and method for transurethral prostate treatment
US6958064B2 (en) * 2003-11-14 2005-10-25 Boston Scientific Scimed, Inc. Systems and methods for performing simultaneous ablation
US20050171574A1 (en) 2003-12-24 2005-08-04 The Regents Of The University Of California Electroporation to interrupt blood flow
US7491200B2 (en) * 2004-03-26 2009-02-17 Arthrocare Corporation Method for treating obstructive sleep disorder includes removing tissue from base of tongue
US20050222646A1 (en) * 2004-04-06 2005-10-06 Kai Kroll Method and device for treating cancer with modified output electrical therapy
WO2005115535A2 (en) 2004-04-23 2005-12-08 Novocure Ltd. Treating a tumor or the like with electric fields at different frequencies
US20050261672A1 (en) * 2004-05-18 2005-11-24 Mark Deem Systems and methods for selective denervation of heart dysrhythmias
AU2005289828A1 (en) * 2004-09-24 2006-04-06 The Board Of Trustees Of The Leland Stanford Junior University Methods and devices for the non-thermal, electrically-induced closure of blood vessels
US7261710B2 (en) 2004-10-13 2007-08-28 Medtronic, Inc. Transurethral needle ablation system
DK1833552T3 (da) 2004-12-07 2010-08-02 Standen Ltd Elektroder til anbringelse af et elektrisk felt in-vivo i en længere tidsperiode
CN102488967B (zh) 2004-12-27 2016-03-30 诺沃库勒有限公司 利用电场从不同方向治疗肿瘤等
US8211104B2 (en) 2005-01-06 2012-07-03 Boston Scientific Scimed, Inc. Co-access bipolar ablation probe
US20060264752A1 (en) * 2005-04-27 2006-11-23 The Regents Of The University Of California Electroporation controlled with real time imaging
DK1899001T3 (en) 2005-06-08 2017-12-04 Novocure Ltd DEVICE FOR CANCER TREATMENT WITH ELECTRIC FIELDS MADE FOR DESIRED LOCATIONS IN A BODY
US20060293730A1 (en) * 2005-06-24 2006-12-28 Boris Rubinsky Methods and systems for treating restenosis sites using electroporation
DK3804809T3 (da) * 2005-10-03 2024-02-12 Novocure Gmbh Optimering af egenskaberne af et elektrisk felt for at øge feltets effekt på proliferende celler
US20070135879A1 (en) 2005-12-08 2007-06-14 Mcintyre Jon T Cylindrical device for delivering energy to tissue
US20080033422A1 (en) 2006-08-04 2008-02-07 Turner Paul F Microwave applicator with margin temperature sensing element
CN101553180B (zh) 2006-09-14 2013-08-07 拉热尔技术有限公司 用于破坏癌细胞的装置

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US7722606B2 (en) 2010-05-25
JP2010503496A (ja) 2010-02-04
US20080071265A1 (en) 2008-03-20
WO2008034103A2 (en) 2008-03-20
HK1138166A1 (en) 2010-08-20
CN101553180B (zh) 2013-08-07
CN101553180A (zh) 2009-10-07
EP2068739A2 (en) 2009-06-17
WO2008034107A3 (en) 2008-11-27
WO2008034103A3 (en) 2008-11-20
US20150066024A1 (en) 2015-03-05
US20110015630A1 (en) 2011-01-20
US20120232550A1 (en) 2012-09-13
US7680543B2 (en) 2010-03-16
US20080071264A1 (en) 2008-03-20
US9308039B2 (en) 2016-04-12
US8109926B2 (en) 2012-02-07
US8915911B2 (en) 2014-12-23
EP2068739A4 (en) 2013-01-23
WO2008034107A2 (en) 2008-03-20
US20080071262A1 (en) 2008-03-20

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