CA2657480A1 - Antagonists of endothelial differentiation gene subfamily 3 (edg-3, s1p3) receptors for prevention and treatment of ocular disorders - Google Patents
Antagonists of endothelial differentiation gene subfamily 3 (edg-3, s1p3) receptors for prevention and treatment of ocular disorders Download PDFInfo
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- CA2657480A1 CA2657480A1 CA002657480A CA2657480A CA2657480A1 CA 2657480 A1 CA2657480 A1 CA 2657480A1 CA 002657480 A CA002657480 A CA 002657480A CA 2657480 A CA2657480 A CA 2657480A CA 2657480 A1 CA2657480 A1 CA 2657480A1
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
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- General Chemical & Material Sciences (AREA)
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- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Ophthalmology & Optometry (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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| US83308006P | 2006-07-25 | 2006-07-25 | |
| US60/833,080 | 2006-07-25 | ||
| PCT/US2007/074351 WO2008014338A2 (en) | 2006-07-25 | 2007-07-25 | Antagonists of endothelial differentiation gene subfamily 3 (edg-3, s1p3) receptors for prevention and treatment of ocular disorders |
Publications (1)
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| CA2657480A1 true CA2657480A1 (en) | 2008-01-31 |
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Family Applications (1)
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| CA002657480A Abandoned CA2657480A1 (en) | 2006-07-25 | 2007-07-25 | Antagonists of endothelial differentiation gene subfamily 3 (edg-3, s1p3) receptors for prevention and treatment of ocular disorders |
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| US (2) | US20080025973A1 (cg-RX-API-DMAC7.html) |
| EP (1) | EP2068856A2 (cg-RX-API-DMAC7.html) |
| JP (1) | JP2009544734A (cg-RX-API-DMAC7.html) |
| KR (1) | KR20090033886A (cg-RX-API-DMAC7.html) |
| CN (1) | CN101505744A (cg-RX-API-DMAC7.html) |
| AU (1) | AU2007279311A1 (cg-RX-API-DMAC7.html) |
| BR (1) | BRPI0714593A2 (cg-RX-API-DMAC7.html) |
| CA (1) | CA2657480A1 (cg-RX-API-DMAC7.html) |
| MX (1) | MX2009000907A (cg-RX-API-DMAC7.html) |
| WO (1) | WO2008014338A2 (cg-RX-API-DMAC7.html) |
| ZA (1) | ZA200900316B (cg-RX-API-DMAC7.html) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN101905023B (zh) * | 2004-07-16 | 2012-07-11 | 杏林制药株式会社 | 有效的医药使用方法及与副作用发生的防御相关的方法 |
| PL1806338T3 (pl) | 2004-10-12 | 2016-07-29 | Kyorin Seiyaku Kk | Sposób wytwarzania chlorowodorku 2-amino-2-[2-[4-(3-benzyloksyfenylotio)-2-chlorofenyio]etylo]-1,3-propanodioiu i jego hydratów oraz produkty pośrednie w ich wytwarzaniu |
| WO2007043433A1 (ja) * | 2005-10-07 | 2007-04-19 | Kyorin Pharmaceutical Co., Ltd. | ２－アミノ－１，３－プロパンジオール誘導体を有効成分とする肝臓疾患治療剤および肝臓疾患治療方法 |
| TWI389683B (zh) * | 2006-02-06 | 2013-03-21 | Kyorin Seiyaku Kk | A therapeutic agent for an inflammatory bowel disease or an inflammatory bowel disease treatment using a 2-amino-1,3-propanediol derivative as an active ingredient |
| KR20090041424A (ko) * | 2006-08-08 | 2009-04-28 | 교린 세이야꾸 가부시키 가이샤 | 아미노알코올 유도체 및 그것들을 유효성분으로 하는 면역 억제제 |
| KR101339976B1 (ko) * | 2006-08-08 | 2013-12-10 | 교린 세이야꾸 가부시키 가이샤 | 아미노인산에스테르 유도체 및 그들을 유효성분으로 하는 ｓ1ｐ 수용체 조절제 |
| JP5452237B2 (ja) | 2008-02-07 | 2014-03-26 | 杏林製薬株式会社 | アミノアルコール誘導体を有効成分とする炎症性腸疾患の治療剤又は予防剤 |
| WO2009117335A2 (en) * | 2008-03-17 | 2009-09-24 | Allergan, Inc. | S1p3 receptor inhibitors for treating inflammation |
| EP2427189A1 (en) * | 2009-05-05 | 2012-03-14 | Allergan, Inc. | S1p3 receptor inhibitors for treating conditions of the eye |
| CA2770894A1 (en) * | 2009-08-11 | 2011-02-17 | Allergan, Inc. | Isothiozoles for treating conditions of the eye |
| MX2012003844A (es) * | 2009-09-30 | 2012-05-08 | Stiefel Res Australia Pty Ltd | Espuma cosmetica. |
| CN102146411B (zh) * | 2011-01-06 | 2013-01-02 | 中国人民解放军第三军医大学第三附属医院 | 新型双功能抗瘢痕和组织纤维化寡聚核苷酸药物 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| WO1995013811A1 (de) * | 1993-11-17 | 1995-05-26 | Byk Nederland Bv | Verwendung substituierter thiazolidinderivate zur behandlung von erhöhtem augeninnendruck |
| US5545626A (en) * | 1994-01-19 | 1996-08-13 | The Trustees Of Columbia University In The City Of New York | Method of treating glaucoma with oligonucleotides |
| US5750652A (en) * | 1994-01-21 | 1998-05-12 | Yale University | Deltex proteins |
| CA2397200C (en) * | 2000-02-09 | 2010-11-23 | Connetics Corporation | Use of relaxin to treat diseases related to vasoconstriction |
| JP2001261575A (ja) * | 2000-03-13 | 2001-09-26 | General Hospital Corp | 血管収縮を調節する方法とその組成物 |
| JP2002332278A (ja) * | 2001-05-08 | 2002-11-22 | Human Science Shinko Zaidan | Ｅｄｇ受容体拮抗作用を有する複素環誘導体 |
| EP2221054A1 (en) * | 2002-04-30 | 2010-08-25 | Alcon, Inc. | CDK inhibitors for lowering intraocular pressure |
| CA2533587A1 (en) * | 2002-07-30 | 2004-02-05 | University Of Virginia Patent Foundation | Compounds active in sphingosine 1-phosphate signaling |
| WO2004019938A1 (en) * | 2002-08-28 | 2004-03-11 | Merck Frosst Canada & Co. | Oxazolidin-2-one and thiazolidin-2-one derivatives for use as ep4 receptor agonists in the treatment of glaucoma |
| FR2845003A1 (fr) * | 2002-09-30 | 2004-04-02 | Merck Sante Sas | Utilisation de derives de thiazolidinedione comme inhibiteurs de l'aldose reductase |
| EP1646611A1 (en) * | 2003-07-15 | 2006-04-19 | Merck & Co., Inc. | Hydroxypyridine cgrp receptor antagonists |
| JP2005247691A (ja) * | 2004-03-01 | 2005-09-15 | Toa Eiyo Ltd | Ｓ１ｐ３受容体拮抗薬 |
| MX2007006706A (es) * | 2004-12-06 | 2007-10-18 | Univ Virginia | Analogos de esfingosina 1-fosfato amida de arilo. |
| US8546452B2 (en) * | 2005-10-12 | 2013-10-01 | Toa Eiyo Ltd. | S1P3 receptor antagonist |
| CN101460458A (zh) * | 2006-02-15 | 2009-06-17 | 阿勒根公司 | 具有1－磷酸－鞘氨醇(s1p)受体拮抗剂生物活性的带芳基或者杂芳基基团的吲哚－3－羧酸的酰胺、酯、硫代酰胺和硫羟酸酯化合物 |
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2007
- 2007-07-25 US US11/828,137 patent/US20080025973A1/en not_active Abandoned
- 2007-07-25 WO PCT/US2007/074351 patent/WO2008014338A2/en not_active Ceased
- 2007-07-25 CN CNA2007800311386A patent/CN101505744A/zh active Pending
- 2007-07-25 KR KR1020097002077A patent/KR20090033886A/ko not_active Ceased
- 2007-07-25 AU AU2007279311A patent/AU2007279311A1/en not_active Abandoned
- 2007-07-25 MX MX2009000907A patent/MX2009000907A/es not_active Application Discontinuation
- 2007-07-25 JP JP2009521989A patent/JP2009544734A/ja active Pending
- 2007-07-25 EP EP07813352A patent/EP2068856A2/en not_active Withdrawn
- 2007-07-25 BR BRPI0714593-4A patent/BRPI0714593A2/pt not_active IP Right Cessation
- 2007-07-25 ZA ZA200900316A patent/ZA200900316B/xx unknown
- 2007-07-25 CA CA002657480A patent/CA2657480A1/en not_active Abandoned
-
2010
- 2010-03-29 US US12/749,331 patent/US20100183629A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| ZA200900316B (en) | 2010-05-26 |
| US20100183629A1 (en) | 2010-07-22 |
| CN101505744A (zh) | 2009-08-12 |
| JP2009544734A (ja) | 2009-12-17 |
| MX2009000907A (es) | 2009-02-04 |
| KR20090033886A (ko) | 2009-04-06 |
| AU2007279311A1 (en) | 2008-01-31 |
| BRPI0714593A2 (pt) | 2013-05-07 |
| US20080025973A1 (en) | 2008-01-31 |
| WO2008014338A2 (en) | 2008-01-31 |
| EP2068856A2 (en) | 2009-06-17 |
| WO2008014338A3 (en) | 2008-12-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |
Effective date: 20140725 |