CA2651002A1 - Use of escitalopram for improving cognition - Google Patents
Use of escitalopram for improving cognition Download PDFInfo
- Publication number
- CA2651002A1 CA2651002A1 CA002651002A CA2651002A CA2651002A1 CA 2651002 A1 CA2651002 A1 CA 2651002A1 CA 002651002 A CA002651002 A CA 002651002A CA 2651002 A CA2651002 A CA 2651002A CA 2651002 A1 CA2651002 A1 CA 2651002A1
- Authority
- CA
- Canada
- Prior art keywords
- condition
- use according
- escitalopram
- medicament
- unit dose
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- WSEQXVZVJXJVFP-FQEVSTJZSA-N escitalopram Chemical compound C1([C@]2(C3=CC=C(C=C3CO2)C#N)CCCN(C)C)=CC=C(F)C=C1 WSEQXVZVJXJVFP-FQEVSTJZSA-N 0.000 title claims abstract description 69
- 229960004341 escitalopram Drugs 0.000 title claims abstract description 67
- 230000019771 cognition Effects 0.000 title claims abstract description 50
- 239000003814 drug Substances 0.000 claims abstract description 26
- 230000003292 diminished effect Effects 0.000 claims abstract description 25
- 238000002360 preparation method Methods 0.000 claims abstract description 23
- 150000001875 compounds Chemical class 0.000 claims abstract description 22
- 150000003839 salts Chemical class 0.000 claims abstract description 21
- 238000011282 treatment Methods 0.000 claims description 22
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- 239000000164 antipsychotic agent Substances 0.000 claims description 12
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- 230000000561 anti-psychotic effect Effects 0.000 claims description 11
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- PMXMIIMHBWHSKN-UHFFFAOYSA-N 3-{2-[4-(6-fluoro-1,2-benzoxazol-3-yl)piperidin-1-yl]ethyl}-9-hydroxy-2-methyl-6,7,8,9-tetrahydropyrido[1,2-a]pyrimidin-4-one Chemical compound FC1=CC=C2C(C3CCN(CC3)CCC=3C(=O)N4CCCC(O)C4=NC=3C)=NOC2=C1 PMXMIIMHBWHSKN-UHFFFAOYSA-N 0.000 claims description 6
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- PXUIZULXJVRBPC-UHFFFAOYSA-N 1'-[3-(3-chloro-10,11-dihydro-5H-dibenzo[b,f]azepin-5-yl)propyl]hexahydro-2H-spiro[imidazo[1,2-a]pyridine-3,4'-piperidin]-2-one Chemical compound C12=CC(Cl)=CC=C2CCC2=CC=CC=C2N1CCCN1CCC2(C(NC3CCCCN32)=O)CC1 PXUIZULXJVRBPC-UHFFFAOYSA-N 0.000 claims description 5
- DKMFBWQBDIGMHM-UHFFFAOYSA-N 1-(4-fluorophenyl)-4-(4-methyl-1-piperidinyl)-1-butanone Chemical compound C1CC(C)CCN1CCCC(=O)C1=CC=C(F)C=C1 DKMFBWQBDIGMHM-UHFFFAOYSA-N 0.000 claims description 5
- MDLAAYDRRZXJIF-UHFFFAOYSA-N 1-[4,4-bis(4-fluorophenyl)butyl]-4-[4-chloro-3-(trifluoromethyl)phenyl]-4-piperidinol Chemical compound C1CC(O)(C=2C=C(C(Cl)=CC=2)C(F)(F)F)CCN1CCCC(C=1C=CC(F)=CC=1)C1=CC=C(F)C=C1 MDLAAYDRRZXJIF-UHFFFAOYSA-N 0.000 claims description 5
- FEBOTPHFXYHVPL-UHFFFAOYSA-N 3-[1-[4-(4-fluorophenyl)-4-oxobutyl]-4-piperidinyl]-1H-benzimidazol-2-one Chemical compound C1=CC(F)=CC=C1C(=O)CCCN1CCC(N2C(NC3=CC=CC=C32)=O)CC1 FEBOTPHFXYHVPL-UHFFFAOYSA-N 0.000 claims description 5
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- ILMHNKKMKWQVCE-UHFFFAOYSA-N 8-fluoro-12-(4-methylpiperazin-1-yl)-6h-[1]benzothiolo[2,3-b][1,5]benzodiazepine Chemical compound C1CN(C)CCN1C1=NC2=CC=C(F)C=C2NC2=C1C1=CC=CC=C1S2 ILMHNKKMKWQVCE-UHFFFAOYSA-N 0.000 claims description 5
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- RKLNONIVDFXQRX-UHFFFAOYSA-N Bromperidol Chemical compound C1CC(O)(C=2C=CC(Br)=CC=2)CCN1CCCC(=O)C1=CC=C(F)C=C1 RKLNONIVDFXQRX-UHFFFAOYSA-N 0.000 claims description 5
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- JNNOSTQEZICQQP-UHFFFAOYSA-N N-desmethylclozapine Chemical compound N=1C2=CC(Cl)=CC=C2NC2=CC=CC=C2C=1N1CCNCC1 JNNOSTQEZICQQP-UHFFFAOYSA-N 0.000 claims description 5
- XCWPUUGSGHNIDZ-UHFFFAOYSA-N Oxypertine Chemical compound C1=2C=C(OC)C(OC)=CC=2NC(C)=C1CCN(CC1)CCN1C1=CC=CC=C1 XCWPUUGSGHNIDZ-UHFFFAOYSA-N 0.000 claims description 5
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- ZGUGWUXLJSTTMA-UHFFFAOYSA-N Promazinum Chemical compound C1=CC=C2N(CCCN(C)C)C3=CC=CC=C3SC2=C1 ZGUGWUXLJSTTMA-UHFFFAOYSA-N 0.000 claims description 5
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- Pain & Pain Management (AREA)
- Hospice & Palliative Care (AREA)
- Addiction (AREA)
- Psychology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DKPA200600621 | 2006-05-02 | ||
| DKPA200600621 | 2006-05-02 | ||
| PCT/DK2007/050050 WO2007124757A2 (en) | 2006-05-02 | 2007-04-30 | Use of escitalopram for improving cognition |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2651002A1 true CA2651002A1 (en) | 2007-11-08 |
Family
ID=38134951
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002651002A Abandoned CA2651002A1 (en) | 2006-05-02 | 2007-04-30 | Use of escitalopram for improving cognition |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP2026793A2 (zh) |
| JP (1) | JP2009535367A (zh) |
| KR (1) | KR20090009820A (zh) |
| CN (1) | CN101426494A (zh) |
| AR (1) | AR060732A1 (zh) |
| AU (1) | AU2007245983A1 (zh) |
| BR (1) | BRPI0710230A2 (zh) |
| CA (1) | CA2651002A1 (zh) |
| EA (1) | EA200870491A1 (zh) |
| IL (1) | IL194628A0 (zh) |
| MX (1) | MX2008013911A (zh) |
| NO (1) | NO20085009L (zh) |
| TW (1) | TW200812993A (zh) |
| WO (1) | WO2007124757A2 (zh) |
| ZA (1) | ZA200808632B (zh) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP4745661B2 (ja) | 2002-08-22 | 2011-08-10 | 大日本住友製薬株式会社 | 統合失調症治療剤 |
| AU2004249621B2 (en) | 2003-06-23 | 2009-08-06 | Dainippon Sumitomo Pharma Co., Ltd. | Therapeutic agent for senile dementia |
| WO2005080976A1 (ja) | 2004-02-20 | 2005-09-01 | Dainippon Sumitomo Pharma Co., Ltd. | 統合失調症の記憶・学習機能障害治療薬のin vivoスクリーニング方法 |
| EA018064B1 (ru) * | 2007-08-03 | 2013-05-30 | Рихтер Гедеон Нирт. | Способ лечения депрессии |
| EP2236138A1 (en) * | 2009-03-30 | 2010-10-06 | PharmaNeuroBoost N.V. | Low dose pipamperone in treating mood and anxiety disorders |
| US8258139B2 (en) | 2010-11-08 | 2012-09-04 | Dainippon Sumitomo Pharma Co., Ltd. | Method of treatment for mental disorders |
| EP3069718A1 (en) * | 2015-03-17 | 2016-09-21 | Universidade do Minho | Citalopram or escitalopram for use in the treatment of neurodegenerative diseases |
| MX2019007389A (es) | 2016-12-20 | 2019-08-16 | Lts Lohmann Therapie Systeme Ag | Sistema terapeutico transdermico que contiene asenapina y polisiloxano o poliisobutileno. |
| US20180193283A1 (en) | 2016-12-20 | 2018-07-12 | Lts Lohmann Therapie-Systeme Ag | Transdermal therapeutic system containing asenapine |
| JP2020525545A (ja) | 2017-06-26 | 2020-08-27 | エルテーエス ローマン テラピー−ジステーメ アーゲー | アセナピンおよびシリコーンアクリルハイブリッドポリマーを含有する経皮治療システム |
| CA3101420A1 (en) | 2018-06-20 | 2019-12-26 | Lts Lohmann Therapie-Systeme Ag | Transdermal therapeutic system containing asenapine |
| KR102051624B1 (ko) * | 2018-11-30 | 2019-12-02 | 아밀로이드솔루션 주식회사 | 트리플루프로마진 또는 이의 약학적으로 허용가능한 염을 유효성분으로 포함하는 퇴행성 뇌질환 치료용 약학 조성물 |
| CN109464436A (zh) * | 2019-01-10 | 2019-03-15 | 高智玉 | 西酞普兰或艾司西酞普兰分别和喹硫平联合在制备治疗精神障碍类疾病的复方制剂中的应用 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DK213290D0 (da) * | 1990-09-06 | 1990-09-06 | Lundbeck & Co As H | Treatment of cerebrovascular disorders |
| SE9803158D0 (sv) * | 1998-09-16 | 1998-09-16 | Astra Ab | A new composition |
| SE9803157D0 (sv) * | 1998-09-16 | 1998-09-16 | Astra Ab | A new composition |
| US6617361B2 (en) * | 1999-11-05 | 2003-09-09 | Be Able, Llc | Behavior chemotherapy |
| ES2266008T3 (es) * | 2000-12-01 | 2007-03-01 | Be Able, Llc | Quimioterapia de comportamiento. |
| WO2002076461A1 (en) * | 2001-03-26 | 2002-10-03 | Serdar Murat Dursun | Combination of reboxetine and citalopram |
| CA2445843A1 (en) * | 2001-05-01 | 2002-11-07 | H. Lundbeck A/S | The use of enantiomeric pure escitalopram |
| US20050014848A1 (en) * | 2002-01-23 | 2005-01-20 | Pfizer Inc. | Combination of serotonin reuptake inhibitors and norephinephrine reuptake inhibitors |
| MXPA05000294A (es) * | 2002-07-30 | 2005-08-19 | Peter Migaly | Terapia combinada para la depresion, prevencion de suicidios y varias condiciones medicas y psiquiatricas. |
| PT1578738E (pt) * | 2002-12-23 | 2008-04-11 | Lundbeck & Co As H | Bromidrato de escitalopram e um método para a sua preparação |
| AU2004269858A1 (en) * | 2003-09-04 | 2005-03-17 | H. Lundbeck A/S | The combination of a serotonin reuptake inhibitor and Loxapine |
| EP1954257A4 (en) * | 2005-10-14 | 2009-05-20 | Lundbeck & Co As H | METHOD FOR TREATING DISORDERS OF THE CENTRAL NERVOUS SYSTEM WITH A LOW-DOSED COMBINATION OF ESCITALOPRAM AND BUPROPION |
| CA2626025A1 (en) * | 2005-10-14 | 2007-04-26 | Forest Laboratories, Inc. | Stable pharmaceutical formulations containing escitalopram and bupropion |
| US20070134322A1 (en) * | 2005-12-14 | 2007-06-14 | Forest Laboratories, Inc. | Modified and pulsatile release pharmaceutical formulations of escitalopram |
-
2007
- 2007-04-25 TW TW096114520A patent/TW200812993A/zh unknown
- 2007-04-30 BR BRPI0710230-5A patent/BRPI0710230A2/pt not_active IP Right Cessation
- 2007-04-30 AR ARP070101874A patent/AR060732A1/es unknown
- 2007-04-30 KR KR1020087025797A patent/KR20090009820A/ko not_active Application Discontinuation
- 2007-04-30 CA CA002651002A patent/CA2651002A1/en not_active Abandoned
- 2007-04-30 WO PCT/DK2007/050050 patent/WO2007124757A2/en active Application Filing
- 2007-04-30 CN CNA200780014675XA patent/CN101426494A/zh active Pending
- 2007-04-30 EA EA200870491A patent/EA200870491A1/ru unknown
- 2007-04-30 MX MX2008013911A patent/MX2008013911A/es not_active Application Discontinuation
- 2007-04-30 EP EP07722705A patent/EP2026793A2/en not_active Withdrawn
- 2007-04-30 AU AU2007245983A patent/AU2007245983A1/en not_active Abandoned
- 2007-04-30 JP JP2009508134A patent/JP2009535367A/ja not_active Withdrawn
-
2008
- 2008-10-07 IL IL194628A patent/IL194628A0/en unknown
- 2008-10-09 ZA ZA2008/08632A patent/ZA200808632B/en unknown
- 2008-12-02 NO NO20085009A patent/NO20085009L/no not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| TW200812993A (en) | 2008-03-16 |
| AR060732A1 (es) | 2008-07-10 |
| CN101426494A (zh) | 2009-05-06 |
| AU2007245983A1 (en) | 2007-11-08 |
| KR20090009820A (ko) | 2009-01-23 |
| BRPI0710230A2 (pt) | 2011-08-02 |
| WO2007124757A3 (en) | 2008-07-24 |
| MX2008013911A (es) | 2008-11-12 |
| IL194628A0 (en) | 2009-08-03 |
| JP2009535367A (ja) | 2009-10-01 |
| NO20085009L (no) | 2008-12-16 |
| ZA200808632B (en) | 2009-12-30 |
| EA200870491A1 (ru) | 2009-04-28 |
| WO2007124757A2 (en) | 2007-11-08 |
| EP2026793A2 (en) | 2009-02-25 |
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| Date | Code | Title | Description |
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| EEER | Examination request | ||
| FZDE | Discontinued |