CA2650864C - Peptides modulateurs de l'activation des macrophages, utilisables pour le traitement de la polyarthrite rhumatoide - Google Patents
Peptides modulateurs de l'activation des macrophages, utilisables pour le traitement de la polyarthrite rhumatoide Download PDFInfo
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- CA2650864C CA2650864C CA2650864A CA2650864A CA2650864C CA 2650864 C CA2650864 C CA 2650864C CA 2650864 A CA2650864 A CA 2650864A CA 2650864 A CA2650864 A CA 2650864A CA 2650864 C CA2650864 C CA 2650864C
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- peptide
- citrullinated
- citrullyl
- residue
- amino acids
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4713—Autoimmune diseases, e.g. Insulin-dependent diabetes mellitus, multiple sclerosis, rheumathoid arthritis, systemic lupus erythematosus; Autoantigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/10—Peptides having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Rheumatology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Zoology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Rehabilitation Therapy (AREA)
- Toxicology (AREA)
- Epidemiology (AREA)
- Pain & Pain Management (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR06/03956 | 2006-05-03 | ||
| FR0603956A FR2900657B1 (fr) | 2006-05-03 | 2006-05-03 | Identification de modulateurs de l'activation des macrophages, utilisables pour le traitement de la polyarthrite rhumatoide |
| PCT/FR2007/000758 WO2007125226A2 (fr) | 2006-05-03 | 2007-05-03 | Peptides modulateurs de l'activation des macrophages, utilisables pour le traitement de la polyarthrite rhumatoïde |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2650864A1 CA2650864A1 (fr) | 2007-11-08 |
| CA2650864C true CA2650864C (fr) | 2015-02-24 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2650864A Active CA2650864C (fr) | 2006-05-03 | 2007-05-03 | Peptides modulateurs de l'activation des macrophages, utilisables pour le traitement de la polyarthrite rhumatoide |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US9388226B2 (enExample) |
| EP (1) | EP2026830B1 (enExample) |
| JP (1) | JP5377288B2 (enExample) |
| CA (1) | CA2650864C (enExample) |
| DK (1) | DK2026830T3 (enExample) |
| ES (1) | ES2392882T3 (enExample) |
| FR (1) | FR2900657B1 (enExample) |
| WO (1) | WO2007125226A2 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2009540847A (ja) * | 2006-06-26 | 2009-11-26 | ディーエスエム アイピー アセッツ ビー．ブイ． | ペプチジルアルギニンデイミナーゼ、およびシトルリン化タンパク質およびペプチド生成におけるその使用 |
| US20110195437A1 (en) * | 2008-08-04 | 2011-08-11 | Synmed Research Gmbh | Method for characterizing, in particular for quantifying, molecular markers that are intracellularly absorbed from tissues by blood macrophages that are recirculated from the tissues into the circulatory system |
| US9975944B2 (en) | 2013-03-12 | 2018-05-22 | Tel Hashomer Medical Research Infrastructure And Services Ltd. | Synthetic peptides for the treatment of autoimmune diseases |
| FR3108515B1 (fr) * | 2020-03-26 | 2022-03-25 | Ct Hospitalier Universitaire Toulouse | Colonne d’aphérèse pour le traitement de la polyarthrite rhumatoïde |
| FR3120877B1 (fr) * | 2021-03-19 | 2025-03-14 | Univ Toulouse 3 Paul Sabatier | Cellule immunitaire comprenant un récepteur Fc à sa surface, et sur lequel est greffé une molécule hybride comprenant un fragment Fc d’anticorps et au moins un peptide citrulliné dérivé de la fibrine, et ses utilisations |
| JPWO2024057793A1 (enExample) * | 2022-09-13 | 2024-03-21 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2155899A (en) * | 1997-11-28 | 1999-06-16 | Innogenetics N.V. | Synthetic peptides containing citrulline recognized by rheumatoid arthritis sera as tools for diagnosis and treatment |
| FR2773078B1 (fr) * | 1997-12-30 | 2000-05-26 | Univ Toulouse | Utilisation de peptides citrullines derives de la filaggrine pour le traitement de la polyarthrite rhumatoide |
| FR2795735B1 (fr) | 1999-07-01 | 2001-09-07 | Univ Toulouse | Derives citrullines de la fibrine et leur utilisation pour le diagnostic ou le traitement de la polyarthrite rhumatoide |
| WO2002048180A2 (de) | 2000-12-12 | 2002-06-20 | Fibrex Medical Research & Development Gmbh | Peptide und/oder proteine sowie verwendung desselben zur herstellung eines therapeutischen und/oder präventiven arzneimittels |
| GB0030309D0 (en) | 2000-12-12 | 2001-01-24 | Univ Aberdeen | Antibodies,Peptides,Analogs and uses thereof |
| WO2006048556A1 (fr) * | 2004-11-04 | 2006-05-11 | Biomerieux | Peptides citrullines derives de la fibrine reconnus par des auto-anticorps specifiques de la polyartrhite rhumatoide, et leurs utilisations |
-
2006
- 2006-05-03 FR FR0603956A patent/FR2900657B1/fr not_active Expired - Fee Related
-
2007
- 2007-05-03 US US12/299,107 patent/US9388226B2/en not_active Expired - Fee Related
- 2007-05-03 WO PCT/FR2007/000758 patent/WO2007125226A2/fr not_active Ceased
- 2007-05-03 EP EP07765933A patent/EP2026830B1/fr not_active Not-in-force
- 2007-05-03 ES ES07765933T patent/ES2392882T3/es active Active
- 2007-05-03 DK DK07765933.2T patent/DK2026830T3/da active
- 2007-05-03 JP JP2009508423A patent/JP5377288B2/ja not_active Expired - Fee Related
- 2007-05-03 CA CA2650864A patent/CA2650864C/fr active Active
Also Published As
| Publication number | Publication date |
|---|---|
| JP5377288B2 (ja) | 2013-12-25 |
| ES2392882T3 (es) | 2012-12-14 |
| DK2026830T3 (da) | 2012-10-08 |
| CA2650864A1 (fr) | 2007-11-08 |
| US20090298778A1 (en) | 2009-12-03 |
| EP2026830B1 (fr) | 2012-06-27 |
| US9388226B2 (en) | 2016-07-12 |
| EP2026830A2 (fr) | 2009-02-25 |
| WO2007125226A3 (fr) | 2007-12-27 |
| WO2007125226A2 (fr) | 2007-11-08 |
| JP2009536182A (ja) | 2009-10-08 |
| FR2900657A1 (fr) | 2007-11-09 |
| FR2900657B1 (fr) | 2009-04-17 |
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