ES2392882T3 - Péptidos moduladores de la activación de macrófagos, utilizables para el tratamiento de la artritis reumatoide - Google Patents

Péptidos moduladores de la activación de macrófagos, utilizables para el tratamiento de la artritis reumatoide Download PDF

Info

Publication number
ES2392882T3
ES2392882T3 ES07765933T ES07765933T ES2392882T3 ES 2392882 T3 ES2392882 T3 ES 2392882T3 ES 07765933 T ES07765933 T ES 07765933T ES 07765933 T ES07765933 T ES 07765933T ES 2392882 T3 ES2392882 T3 ES 2392882T3
Authority
ES
Spain
Prior art keywords
peptide
citrullyl
citrullinated
moiety
amino acids
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
ES07765933T
Other languages
English (en)
Spanish (es)
Inventor
Cyril Clavel
Mireille Sebbag
Maria Leonor Nogueira
Guy Serre
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universite de Toulouse
Original Assignee
Universite Toulouse III Paul Sabatier
Universite de Toulouse
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Universite Toulouse III Paul Sabatier, Universite de Toulouse filed Critical Universite Toulouse III Paul Sabatier
Application granted granted Critical
Publication of ES2392882T3 publication Critical patent/ES2392882T3/es
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4713Autoimmune diseases, e.g. Insulin-dependent diabetes mellitus, multiple sclerosis, rheumathoid arthritis, systemic lupus erythematosus; Autoantigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10Peptides having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Rehabilitation Therapy (AREA)
  • Toxicology (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
ES07765933T 2006-05-03 2007-05-03 Péptidos moduladores de la activación de macrófagos, utilizables para el tratamiento de la artritis reumatoide Active ES2392882T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0603956 2006-05-03
FR0603956A FR2900657B1 (fr) 2006-05-03 2006-05-03 Identification de modulateurs de l'activation des macrophages, utilisables pour le traitement de la polyarthrite rhumatoide
PCT/FR2007/000758 WO2007125226A2 (fr) 2006-05-03 2007-05-03 Peptides modulateurs de l'activation des macrophages, utilisables pour le traitement de la polyarthrite rhumatoïde

Publications (1)

Publication Number Publication Date
ES2392882T3 true ES2392882T3 (es) 2012-12-14

Family

ID=37401063

Family Applications (1)

Application Number Title Priority Date Filing Date
ES07765933T Active ES2392882T3 (es) 2006-05-03 2007-05-03 Péptidos moduladores de la activación de macrófagos, utilizables para el tratamiento de la artritis reumatoide

Country Status (8)

Country Link
US (1) US9388226B2 (enExample)
EP (1) EP2026830B1 (enExample)
JP (1) JP5377288B2 (enExample)
CA (1) CA2650864C (enExample)
DK (1) DK2026830T3 (enExample)
ES (1) ES2392882T3 (enExample)
FR (1) FR2900657B1 (enExample)
WO (1) WO2007125226A2 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009540847A (ja) * 2006-06-26 2009-11-26 ディーエスエム アイピー アセッツ ビー.ブイ. ペプチジルアルギニンデイミナーゼ、およびシトルリン化タンパク質およびペプチド生成におけるその使用
US20110195437A1 (en) * 2008-08-04 2011-08-11 Synmed Research Gmbh Method for characterizing, in particular for quantifying, molecular markers that are intracellularly absorbed from tissues by blood macrophages that are recirculated from the tissues into the circulatory system
US9975944B2 (en) 2013-03-12 2018-05-22 Tel Hashomer Medical Research Infrastructure And Services Ltd. Synthetic peptides for the treatment of autoimmune diseases
FR3108515B1 (fr) * 2020-03-26 2022-03-25 Ct Hospitalier Universitaire Toulouse Colonne d’aphérèse pour le traitement de la polyarthrite rhumatoïde
FR3120877B1 (fr) * 2021-03-19 2025-03-14 Univ Toulouse 3 Paul Sabatier Cellule immunitaire comprenant un récepteur Fc à sa surface, et sur lequel est greffé une molécule hybride comprenant un fragment Fc d’anticorps et au moins un peptide citrulliné dérivé de la fibrine, et ses utilisations
JPWO2024057793A1 (enExample) * 2022-09-13 2024-03-21

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2155899A (en) * 1997-11-28 1999-06-16 Innogenetics N.V. Synthetic peptides containing citrulline recognized by rheumatoid arthritis sera as tools for diagnosis and treatment
FR2773078B1 (fr) * 1997-12-30 2000-05-26 Univ Toulouse Utilisation de peptides citrullines derives de la filaggrine pour le traitement de la polyarthrite rhumatoide
FR2795735B1 (fr) 1999-07-01 2001-09-07 Univ Toulouse Derives citrullines de la fibrine et leur utilisation pour le diagnostic ou le traitement de la polyarthrite rhumatoide
WO2002048180A2 (de) 2000-12-12 2002-06-20 Fibrex Medical Research & Development Gmbh Peptide und/oder proteine sowie verwendung desselben zur herstellung eines therapeutischen und/oder präventiven arzneimittels
GB0030309D0 (en) 2000-12-12 2001-01-24 Univ Aberdeen Antibodies,Peptides,Analogs and uses thereof
WO2006048556A1 (fr) * 2004-11-04 2006-05-11 Biomerieux Peptides citrullines derives de la fibrine reconnus par des auto-anticorps specifiques de la polyartrhite rhumatoide, et leurs utilisations

Also Published As

Publication number Publication date
JP5377288B2 (ja) 2013-12-25
DK2026830T3 (da) 2012-10-08
CA2650864A1 (fr) 2007-11-08
US20090298778A1 (en) 2009-12-03
EP2026830B1 (fr) 2012-06-27
US9388226B2 (en) 2016-07-12
EP2026830A2 (fr) 2009-02-25
WO2007125226A3 (fr) 2007-12-27
WO2007125226A2 (fr) 2007-11-08
JP2009536182A (ja) 2009-10-08
FR2900657A1 (fr) 2007-11-09
FR2900657B1 (fr) 2009-04-17
CA2650864C (fr) 2015-02-24

Similar Documents

Publication Publication Date Title
ES2392882T3 (es) Péptidos moduladores de la activación de macrófagos, utilizables para el tratamiento de la artritis reumatoide
JP2016526014A (ja) インターロイキン−10組成物及びその使用
ES2747363T3 (es) Estructuras inmunorreguladoras de proteínas que se encuentran normalmente
AU2016378387A1 (en) Interleukin-15 compositions and uses thereof
JP2016519108A (ja) インターロイキン−10を疾病及び疾患の治療に用いる方法
ES2253241T3 (es) Detivados cilutrinados de la fibrina y su utilizacion para el diagnostico o el tratamiento de la poliartritis reumatoide.
CA2324511A1 (en) Novel peptides for the treatment, prophylaxis, diagnosis and monitoring of autoimmune diseases
KR100328112B1 (ko) 류마토이드관절염병원관련관절염성펩티드에대항하는면역보호유도에유용한백신조성물과방법
JP2003517284A (ja) 免疫応答を変調する方法及び組成物
JP2021510169A (ja) アトピー性皮膚炎の治療及び/または予防のためのil−31のペプチド免疫原ならびにその製剤
ES2971898T3 (es) Nuevos compuestos peptídicos obtenidos a partir de IL-4-/IL-13 para el tratamiento o la prevención de enfermeda-des neurodegenerativas o neuroinflamatorias
EP3294901A1 (en) Autoantigens for diagnosis of rheumatoid arthritis
Feng et al. Isolation and potential immunological characterization of TPSGLVY, a novel bursal septpeptide isolated from the bursa of Fabricius
US6849596B1 (en) Regulatory/unfolding peptides of ezrin
RU2233290C2 (ru) Новые пептиды для применения в иммунотерапии аутоиммунных заболеваний
WO1996006630A1 (en) Methods and compositions for modulating a t cell response
KR20000070542A (ko) Ⅱ형 콜라겐에 특이적인 t 세포 에피토프를 포함하는 펩티드
JP4557421B2 (ja) 自己免疫疾患を治療するためのフィラグリン由来シトルリンペプチドの使用
JP2001504451A (ja) 自己免疫疾患の診断薬と治療薬となるペプチド類
FR2908134A1 (fr) Identification de modulateurs de l'activation des macrophages, utilisables pour le traitement de la polyarthrite rhumatoide
HK40025696A (en) Peptide immunogens of il-31 and formulations thereof for the treatment and/or prevention of atopic dermatitis
JPH0654906A (ja) ポリペプチドおよびそれを用いた抗血小板抗体吸着材
BR102016030946A2 (pt) Inibidor de pla2, peptídeos sintéticos derivados, suas sequencias reversas e uso.
MXPA98008866A (en) Novedosos peptidos suitable for use in antig specific immunosuppressive therapy