DK2026830T3 - Peptidmodulatorer for aktiviteten af makrofager, der er egnet til behandling af rheumatoid polyarthritis - Google Patents

Peptidmodulatorer for aktiviteten af makrofager, der er egnet til behandling af rheumatoid polyarthritis

Info

Publication number
DK2026830T3
DK2026830T3 DK07765933.2T DK07765933T DK2026830T3 DK 2026830 T3 DK2026830 T3 DK 2026830T3 DK 07765933 T DK07765933 T DK 07765933T DK 2026830 T3 DK2026830 T3 DK 2026830T3
Authority
DK
Denmark
Prior art keywords
activity
treatment
peptide modulators
rheumatoid polyarthritis
macrophages
Prior art date
Application number
DK07765933.2T
Other languages
English (en)
Inventor
Cyril Clavel
Mireille Sebbag
Maria Leonor Nogueira
Guy Serre
Original Assignee
Univ Toulouse
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Toulouse filed Critical Univ Toulouse
Application granted granted Critical
Publication of DK2026830T3 publication Critical patent/DK2026830T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4713—Autoimmune diseases, e.g. Insulin-dependent diabetes mellitus, multiple sclerosis, rheumathoid arthritis, systemic lupus erythematosus; Autoantigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Rehabilitation Therapy (AREA)
  • Toxicology (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DK07765933.2T 2006-05-03 2007-05-03 Peptidmodulatorer for aktiviteten af makrofager, der er egnet til behandling af rheumatoid polyarthritis DK2026830T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0603956A FR2900657B1 (fr) 2006-05-03 2006-05-03 Identification de modulateurs de l'activation des macrophages, utilisables pour le traitement de la polyarthrite rhumatoide
PCT/FR2007/000758 WO2007125226A2 (fr) 2006-05-03 2007-05-03 Peptides modulateurs de l'activation des macrophages, utilisables pour le traitement de la polyarthrite rhumatoïde

Publications (1)

Publication Number Publication Date
DK2026830T3 true DK2026830T3 (da) 2012-10-08

Family

ID=37401063

Family Applications (1)

Application Number Title Priority Date Filing Date
DK07765933.2T DK2026830T3 (da) 2006-05-03 2007-05-03 Peptidmodulatorer for aktiviteten af makrofager, der er egnet til behandling af rheumatoid polyarthritis

Country Status (8)

Country Link
US (1) US9388226B2 (da)
EP (1) EP2026830B1 (da)
JP (1) JP5377288B2 (da)
CA (1) CA2650864C (da)
DK (1) DK2026830T3 (da)
ES (1) ES2392882T3 (da)
FR (1) FR2900657B1 (da)
WO (1) WO2007125226A2 (da)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2008000714A1 (en) * 2006-06-26 2008-01-03 Dsm Ip Assets B.V. Peptidylarginine deiminase and uses thereof in the production of citrullinated proteins and peptides
WO2010015633A1 (de) * 2008-08-04 2010-02-11 Synmed Research Gmbh Verfahren zur charakterisierung, insbesondere quantifizierung, von durch, aus dem gewebe in die blutbahn rezirkulierten, blutmakrophagen intrazellulär aus gewebe aufgenommenen molekularen markern sowie analyseanordnung zur durchführung des verfahrens
EP2968435B1 (en) 2013-03-12 2019-01-30 Tel HaShomer Medical Research Infrastructure and Services Ltd. Synthetic peptides for the treatment of autoimmune diseases
FR3120877A1 (fr) * 2021-03-19 2022-09-23 Institut National De La Sante Et De La Recherche Medicale Cellule immunitaire comprenant un récepteur Fc à sa surface, et sur lequel est greffé une molécule hybride comprenant un fragment Fc d’anticorps et au moins un peptide citrulliné dérivé de la fibrine, et ses utilisations
WO2024057793A1 (ja) * 2022-09-13 2024-03-21 国立大学法人信州大学 癌転移を抑制するシトルリン化ペプチド

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1034186A2 (en) * 1997-11-28 2000-09-13 Innogenetics N.V. Synthetic peptides containing citrulline recognized by rheumatoid arthritis sera as tools for diagnosis and treatment
FR2773078B1 (fr) * 1997-12-30 2000-05-26 Univ Toulouse Utilisation de peptides citrullines derives de la filaggrine pour le traitement de la polyarthrite rhumatoide
FR2795735B1 (fr) * 1999-07-01 2001-09-07 Univ Toulouse Derives citrullines de la fibrine et leur utilisation pour le diagnostic ou le traitement de la polyarthrite rhumatoide
GB0030309D0 (en) * 2000-12-12 2001-01-24 Univ Aberdeen Antibodies,Peptides,Analogs and uses thereof
DE50114771D1 (de) * 2000-12-12 2009-04-23 Fibrex Medical Res & Dev Gmbh Peptide und/oder Proteine sowie ihre Verwendung zur Herstellung eines therapeutischen und/oder präventiven Arzneimittels
WO2006048556A1 (fr) 2004-11-04 2006-05-11 Biomerieux Peptides citrullines derives de la fibrine reconnus par des auto-anticorps specifiques de la polyartrhite rhumatoide, et leurs utilisations

Also Published As

Publication number Publication date
US20090298778A1 (en) 2009-12-03
FR2900657B1 (fr) 2009-04-17
US9388226B2 (en) 2016-07-12
EP2026830A2 (fr) 2009-02-25
WO2007125226A2 (fr) 2007-11-08
CA2650864A1 (fr) 2007-11-08
FR2900657A1 (fr) 2007-11-09
ES2392882T3 (es) 2012-12-14
WO2007125226A3 (fr) 2007-12-27
JP2009536182A (ja) 2009-10-08
EP2026830B1 (fr) 2012-06-27
CA2650864C (fr) 2015-02-24
JP5377288B2 (ja) 2013-12-25

Similar Documents

Publication Publication Date Title
DK2046819T3 (da) Fremgangsmåder til forøgelse af secernering af polypeptider med biologisk aktivitet
DK1928438T3 (da) Anvendelse af ibudilast til behandling af stofafhængighed
DK1898903T3 (da) Inhibitorer af Akt-aktivitet
DK2500047T3 (da) Lægemiddelfrigivende coatinger til medicinske indretninger
DK3403657T3 (da) Anvendelse af oligouronater til behandling af slimhyperviskositet
DK1874781T3 (da) Dihydrothienopyrimidiner til behandling af inflammatoriske sygdomme
DK2120604T3 (da) Fremgangsmåde til fraktionering af havre, produkter derved opnået, og anvendelser deraf
DK2019683T4 (da) Indgivelse af vækstfaktorer til behandling af CNS-lidelser
DK2139390T3 (da) Fremgangsmåde til evaluering af effektiviteten af kommerciel kommunikation
DK1833799T3 (da) 3-phenyl-pyrazol derivater, som modulatorer af 5-HT-2a-serotonin receptor nyttig til behandlingen af sygdomme relateret hertil
DK2545939T3 (da) Tetrahydrobiopterin til behandling af tilstande associeret med forhøjede phenylalaninniveauer
DK2048941T3 (da) Fremgangsmåde til opdræt af rovmider
DK1868600T3 (da) Spirocyklisk cyclohexanderivat til behandling af stofafhængighed
CR10851A (es) Inhibidores de la actividad de la akt
DK1708992T3 (da) Sulfonamidderivater til behandling af sygdomme
DK2959894T3 (da) S1p-receptormodulatorer til behandling af multipel sklerose
DK2086944T3 (da) Fremgangsmåde til fremstilling af difluormethylpyrazolylcarboxylater
DK2117523T3 (da) Inhibitorer af AKT-aktivitet
DK1893586T3 (da) Fremgangsmåde til fremstilling af 1-alkyl-3-phenyluraciler
DK3225251T3 (da) Modulering af pro-neurotrofinaktivitet
DK1888294T3 (da) Fremgangsmåde til hårdlodning af artikler af rustfrit stål
FI20060217A (fi) Sprinkleri
DK1947933T3 (da) System til styret udbringning af herbicider
DK1942967T3 (da) Fremgangsmåde til dosering af medikamenter
DK2010184T3 (da) Implatanter til behandlingen af dopamin associerede tilstande