FR2900657B1 - Identification de modulateurs de l'activation des macrophages, utilisables pour le traitement de la polyarthrite rhumatoide - Google Patents

Identification de modulateurs de l'activation des macrophages, utilisables pour le traitement de la polyarthrite rhumatoide

Info

Publication number
FR2900657B1
FR2900657B1 FR0603956A FR0603956A FR2900657B1 FR 2900657 B1 FR2900657 B1 FR 2900657B1 FR 0603956 A FR0603956 A FR 0603956A FR 0603956 A FR0603956 A FR 0603956A FR 2900657 B1 FR2900657 B1 FR 2900657B1
Authority
FR
France
Prior art keywords
identification
useful
treatment
rheumatoid arthritis
macrophage activation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR0603956A
Other languages
English (en)
French (fr)
Other versions
FR2900657A1 (fr
Inventor
Cyril Clavier
Mireille Sebbag
Maria Leonor Nogueira
Guy Serre
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universite de Toulouse
Original Assignee
Universite Toulouse III Paul Sabatier
Universite de Toulouse
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to FR0603956A priority Critical patent/FR2900657B1/fr
Application filed by Universite Toulouse III Paul Sabatier, Universite de Toulouse filed Critical Universite Toulouse III Paul Sabatier
Priority to PCT/FR2007/000758 priority patent/WO2007125226A2/fr
Priority to JP2009508423A priority patent/JP5377288B2/ja
Priority to US12/299,107 priority patent/US9388226B2/en
Priority to CA2650864A priority patent/CA2650864C/fr
Priority to EP07765933A priority patent/EP2026830B1/fr
Priority to DK07765933.2T priority patent/DK2026830T3/da
Priority to ES07765933T priority patent/ES2392882T3/es
Publication of FR2900657A1 publication Critical patent/FR2900657A1/fr
Application granted granted Critical
Publication of FR2900657B1 publication Critical patent/FR2900657B1/fr
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
    • C07K14/4713—Autoimmune diseases, e.g. Insulin-dependent diabetes mellitus, multiple sclerosis, rheumathoid arthritis, systemic lupus erythematosus; Autoantigens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/10—Peptides having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Zoology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Rehabilitation Therapy (AREA)
  • Toxicology (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
FR0603956A 2006-05-03 2006-05-03 Identification de modulateurs de l'activation des macrophages, utilisables pour le traitement de la polyarthrite rhumatoide Expired - Fee Related FR2900657B1 (fr)

Priority Applications (8)

Application Number Priority Date Filing Date Title
FR0603956A FR2900657B1 (fr) 2006-05-03 2006-05-03 Identification de modulateurs de l'activation des macrophages, utilisables pour le traitement de la polyarthrite rhumatoide
JP2009508423A JP5377288B2 (ja) 2006-05-03 2007-05-03 慢性関節リウマチの治療に有用な、マクロファージの活性を調整するペプチド
US12/299,107 US9388226B2 (en) 2006-05-03 2007-05-03 Peptides modulating the activity of macrophages, useable for the treatment of rheumatoid arthritis
CA2650864A CA2650864C (fr) 2006-05-03 2007-05-03 Peptides modulateurs de l'activation des macrophages, utilisables pour le traitement de la polyarthrite rhumatoide
PCT/FR2007/000758 WO2007125226A2 (fr) 2006-05-03 2007-05-03 Peptides modulateurs de l'activation des macrophages, utilisables pour le traitement de la polyarthrite rhumatoïde
EP07765933A EP2026830B1 (fr) 2006-05-03 2007-05-03 Peptides modulateurs de l'activation des macrophages, utilisables pour le traitement de la polyarthrite rhumatoïde
DK07765933.2T DK2026830T3 (da) 2006-05-03 2007-05-03 Peptidmodulatorer for aktiviteten af makrofager, der er egnet til behandling af rheumatoid polyarthritis
ES07765933T ES2392882T3 (es) 2006-05-03 2007-05-03 Péptidos moduladores de la activación de macrófagos, utilizables para el tratamiento de la artritis reumatoide

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0603956A FR2900657B1 (fr) 2006-05-03 2006-05-03 Identification de modulateurs de l'activation des macrophages, utilisables pour le traitement de la polyarthrite rhumatoide

Publications (2)

Publication Number Publication Date
FR2900657A1 FR2900657A1 (fr) 2007-11-09
FR2900657B1 true FR2900657B1 (fr) 2009-04-17

Family

ID=37401063

Family Applications (1)

Application Number Title Priority Date Filing Date
FR0603956A Expired - Fee Related FR2900657B1 (fr) 2006-05-03 2006-05-03 Identification de modulateurs de l'activation des macrophages, utilisables pour le traitement de la polyarthrite rhumatoide

Country Status (8)

Country Link
US (1) US9388226B2 (enExample)
EP (1) EP2026830B1 (enExample)
JP (1) JP5377288B2 (enExample)
CA (1) CA2650864C (enExample)
DK (1) DK2026830T3 (enExample)
ES (1) ES2392882T3 (enExample)
FR (1) FR2900657B1 (enExample)
WO (1) WO2007125226A2 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009540847A (ja) * 2006-06-26 2009-11-26 ディーエスエム アイピー アセッツ ビー．ブイ． ペプチジルアルギニンデイミナーゼ、およびシトルリン化タンパク質およびペプチド生成におけるその使用
US20110195437A1 (en) * 2008-08-04 2011-08-11 Synmed Research Gmbh Method for characterizing, in particular for quantifying, molecular markers that are intracellularly absorbed from tissues by blood macrophages that are recirculated from the tissues into the circulatory system
US9975944B2 (en) 2013-03-12 2018-05-22 Tel Hashomer Medical Research Infrastructure And Services Ltd. Synthetic peptides for the treatment of autoimmune diseases
FR3108515B1 (fr) * 2020-03-26 2022-03-25 Ct Hospitalier Universitaire Toulouse Colonne d’aphérèse pour le traitement de la polyarthrite rhumatoïde
FR3120877B1 (fr) * 2021-03-19 2025-03-14 Univ Toulouse 3 Paul Sabatier Cellule immunitaire comprenant un récepteur Fc à sa surface, et sur lequel est greffé une molécule hybride comprenant un fragment Fc d’anticorps et au moins un peptide citrulliné dérivé de la fibrine, et ses utilisations
JPWO2024057793A1 (enExample) * 2022-09-13 2024-03-21

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2155899A (en) * 1997-11-28 1999-06-16 Innogenetics N.V. Synthetic peptides containing citrulline recognized by rheumatoid arthritis sera as tools for diagnosis and treatment
FR2773078B1 (fr) * 1997-12-30 2000-05-26 Univ Toulouse Utilisation de peptides citrullines derives de la filaggrine pour le traitement de la polyarthrite rhumatoide
FR2795735B1 (fr) 1999-07-01 2001-09-07 Univ Toulouse Derives citrullines de la fibrine et leur utilisation pour le diagnostic ou le traitement de la polyarthrite rhumatoide
WO2002048180A2 (de) 2000-12-12 2002-06-20 Fibrex Medical Research & Development Gmbh Peptide und/oder proteine sowie verwendung desselben zur herstellung eines therapeutischen und/oder präventiven arzneimittels
GB0030309D0 (en) 2000-12-12 2001-01-24 Univ Aberdeen Antibodies,Peptides,Analogs and uses thereof
WO2006048556A1 (fr) * 2004-11-04 2006-05-11 Biomerieux Peptides citrullines derives de la fibrine reconnus par des auto-anticorps specifiques de la polyartrhite rhumatoide, et leurs utilisations

Also Published As

Publication number Publication date
JP5377288B2 (ja) 2013-12-25
ES2392882T3 (es) 2012-12-14
DK2026830T3 (da) 2012-10-08
CA2650864A1 (fr) 2007-11-08
US20090298778A1 (en) 2009-12-03
EP2026830B1 (fr) 2012-06-27
US9388226B2 (en) 2016-07-12
EP2026830A2 (fr) 2009-02-25
WO2007125226A3 (fr) 2007-12-27
WO2007125226A2 (fr) 2007-11-08
JP2009536182A (ja) 2009-10-08
FR2900657A1 (fr) 2007-11-09
CA2650864C (fr) 2015-02-24

Similar Documents

Publication Publication Date Title
EP2334800A4 (en) MICRO-ORGANISMS FOR THE PREPARATION OF 1,4-BANDALIUM
FR2915201B1 (fr) Procede pour la preparation d'anhydrides polyalcenylsucciniques
EP2049710A4 (en) MASTER ELECTRODE AND METHOD OF MANUFACTURING THEREOF
EP2119477A4 (en) COMPOSITION FOR THE TREATMENT OF XEROSTOMY OR DRY MOUTH
EP1838320A4 (en) CXCR4 ANTAGONISTS FOR THE TREATMENT OF MEDICAL PROBLEMS
FR2890393B1 (fr) Suspension de polissage polymere pour le retrait de barrieres
EP2027956A4 (en) PROCESS FOR THE PRODUCTION OF COLLODIAL GOLD AND COLLODIAL GOLD
MA28791B1 (fr) Derives de piperazine convenant pour le traitement de troubles gastro-intestinaux
EP1931691A4 (en) ODKASE INHIBITORS FOR THE TREATMENT OF MALARIA
FR2920320B1 (fr) Procede pour la production de fluorapatite, fluorapatite et appareil d'adsorption.
EP2376091A4 (en) NEW TARGETS FOR THE TREATMENT OF HYPERCHOLESTERINMIA
FR2907456B1 (fr) Procede de preparation d'oligomeres ou polymeres de cyclodestrines.
EP2402431A4 (en) AGGREGATE FOR THE PREVENTION OR REDUCTION OF ADIPOSITAS
BRPI0820440A2 (pt) Inibidores aldh-2 no tratamento de desordens psiquiátricas
FR2944275B1 (fr) Procede pour la production de fluoroapatite, fluoroapatite et appareil d'adsorption
ZA200806455B (en) Use of 2-imidazoles for the treatment of CNS disorders
EP2265686A4 (en) VISCOSITY DERIVATIVES FOR WATER-BASED SLAUGHS
EP1813700A4 (en) DEVICE FOR PREPARING CRYSTAL
FR2907011B1 (fr) Utilisation de la citrulline pour le traitement des etats de denutrition
IL192877A0 (en) Use of 2-imidazoles for the treatment of cns disorders
EP2087886A4 (en) THERAPEUTIC AGENT AGAINST RHEUMATOID ARTHRITIS
FR2900657B1 (fr) Identification de modulateurs de l'activation des macrophages, utilisables pour le traitement de la polyarthrite rhumatoide
EP1849763A4 (en) METHOD FOR SYNTHESIS OF (METH) ACRYLIC ACID T-BUTYL SAMPLE
FR2903040B1 (fr) Presse vibrante pour la production d'elements de construction
EP1872730A4 (en) TREATMENT INSTRUMENT FOR AN ENDOSCOPE

Legal Events

Date Code Title Description
RM Correction of a material error
ST Notification of lapse

Effective date: 20150130