CA2647161A1 - Probiotic strain and antimicrobial peptide derived therefrom - Google Patents

Probiotic strain and antimicrobial peptide derived therefrom Download PDF

Info

Publication number
CA2647161A1
CA2647161A1 CA002647161A CA2647161A CA2647161A1 CA 2647161 A1 CA2647161 A1 CA 2647161A1 CA 002647161 A CA002647161 A CA 002647161A CA 2647161 A CA2647161 A CA 2647161A CA 2647161 A1 CA2647161 A1 CA 2647161A1
Authority
CA
Canada
Prior art keywords
peptide
st4sa
strain
seq
concentration
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002647161A
Other languages
English (en)
French (fr)
Inventor
Leon Milner Theodore Dicks
Svetoslav Dimitrov Todorov
Hendriette Knoetze
Marelize Brink
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Cipla Medpro Pty Ltd
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from ZA200604035A external-priority patent/ZA200604035B/xx
Application filed by Individual filed Critical Individual
Publication of CA2647161A1 publication Critical patent/CA2647161A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • C12N1/205Bacterial isolates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01NPRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N63/00Biocides, pest repellants or attractants, or plant growth regulators containing microorganisms, viruses, microbial fungi, animals or substances produced by, or obtained from, microorganisms, viruses, microbial fungi or animals, e.g. enzymes or fermentates
    • A01N63/50Isolated enzymes; Isolated proteins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/02Local antiseptics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/01Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/46Streptococcus ; Enterococcus; Lactococcus
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Mycology (AREA)
  • Biomedical Technology (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • General Chemical & Material Sciences (AREA)
  • Plant Pathology (AREA)
  • Agronomy & Crop Science (AREA)
  • Pest Control & Pesticides (AREA)
  • Dentistry (AREA)
  • Environmental Sciences (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
CA002647161A 2006-05-28 2007-05-25 Probiotic strain and antimicrobial peptide derived therefrom Abandoned CA2647161A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ZA2006/04035 2006-05-28
ZA200604035A ZA200604035B (en) 2005-05-31 2006-05-28 Improved grenade launcher
PCT/IB2007/051982 WO2007138538A2 (en) 2006-05-28 2007-05-25 Probiotic strain and antimicrobial peptide derived therefrom

Publications (1)

Publication Number Publication Date
CA2647161A1 true CA2647161A1 (en) 2007-12-06

Family

ID=38779065

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002647161A Abandoned CA2647161A1 (en) 2006-05-28 2007-05-25 Probiotic strain and antimicrobial peptide derived therefrom

Country Status (13)

Country Link
US (2) US7951385B2 (enExample)
EP (1) EP2021457B1 (enExample)
JP (1) JP2009538614A (enExample)
KR (1) KR101521123B1 (enExample)
CN (1) CN101454440B (enExample)
AP (1) AP2841A (enExample)
AU (1) AU2007266675B2 (enExample)
CA (1) CA2647161A1 (enExample)
EA (1) EA017558B1 (enExample)
IL (2) IL195520A0 (enExample)
NO (1) NO20084577L (enExample)
NZ (1) NZ571619A (enExample)
WO (1) WO2007138538A2 (enExample)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2009538614A (ja) * 2006-05-28 2009-11-12 シプラ メドプロ リサーチ アンド デヴェロップメント (プロプライエタリー) リミテッド プロバイオティクス菌株及びこれに由来する抗菌性ペプチド
US8357519B2 (en) * 2008-11-19 2013-01-22 The Ohio State University Methods and processes for producing esters
WO2011045764A1 (en) * 2009-10-15 2011-04-21 Cipla Medpro Research And Development (Pty) Ltd A product for delivering antimicrobially active substances to an infected site
JP5881017B2 (ja) * 2010-11-05 2016-03-09 国立大学法人広島大学 籾殻または玄米から単離された植物乳酸菌およびその利用
WO2012148891A1 (en) * 2011-04-29 2012-11-01 Evonik Degussa Corporation Peptide-lipid conjugates and uses thereof
RU2532227C1 (ru) * 2013-10-23 2014-10-27 Федеральное бюджетное учреждение науки Государственный научный центр прикладной микробиологии и биотехнологии (ФБУН ГНЦ ПМБ) Штамм enterоcoccus mundtii, продуцирующий субстанцию пептидной природы с антилистериозной активностью
RU2599430C1 (ru) * 2015-07-23 2016-10-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Горский государственный аграрный университет" ШТАММ ЛАКТОБАКТЕРИЙ Enterococcus mundtii - ПРОДУЦЕНТ МОЛОЧНОЙ КИСЛОТЫ И АНТИБИОТИЧЕСКИХ ВЕЩЕСТВ
US9944960B2 (en) * 2015-11-17 2018-04-17 Premier Research Labs, Lp Process for microbial production of dihydrolipoic acid and extraction of dihydrolipoic acid with edible oils
CN105385636A (zh) * 2015-12-07 2016-03-09 江南大学 一株产细菌素的肠膜明串珠菌及其应用
JP2019510036A (ja) 2016-03-31 2019-04-11 ゴジョ・インダストリーズ・インコーポレイテッド プロバイオティクス/プレバイオティクス有効成分を含む清浄剤組成物
EP3436156A1 (en) 2016-03-31 2019-02-06 Gojo Industries, Inc. Antimicrobial peptide stimulating cleansing composition
KR101722255B1 (ko) * 2016-04-22 2017-04-03 주식회사 폴인브레드 쌀과 쌀누룩을 이용한 자연발효종 제조방법
US11564879B2 (en) 2016-11-23 2023-01-31 Gojo Industries, Inc. Sanitizer composition with probiotic/prebiotic active ingredient
WO2019060115A1 (en) * 2017-09-19 2019-03-28 Advaxis, Inc. COMPOSITIONS AND METHODS FOR LYOPHILIZATION OF BACTERIA OR LISTERIA STRAINS
WO2019151371A1 (ja) * 2018-01-31 2019-08-08 ニュートリー株式会社 肺炎球菌感染症の予防及び/又は治療剤
KR102076089B1 (ko) 2018-10-02 2020-02-11 서울대학교 산학협력단 니신 z 생산능이 우수한 락토코커스 락티스 서브스페시스 락티스 ldtm 6804 신균주(kctc 13564bp)
CN109456911B (zh) * 2018-10-10 2019-10-18 南京林业大学 一株蒙氏肠球菌HcM7及其应用
CN110846260B (zh) * 2019-12-18 2021-03-02 江南大学 一株降低生物胺的肉葡萄球菌及其应用
KR20240115407A (ko) * 2023-01-18 2024-07-26 조선대학교산학협력단 오리 유래 항균 펩타이드로부터 설계된 신규 항균 펩타이드 및 이의 용도

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH1084969A (ja) 1996-09-19 1998-04-07 Chemo Sero Therapeut Res Inst ヘモフィルス・パラガリナルム由来新規ポリペプチド及びその製法
US7655775B2 (en) * 1997-09-05 2010-02-02 Canbiocin, Inc. Expression vectors for treating bacterial infections
AU7898700A (en) 1999-10-22 2001-05-08 Shanghai Bio Road Gene Development Ltd. A novel polypeptide-rna binding protein 33 and polynucleotide encoding said polypeptide
GB0027761D0 (en) 2000-11-14 2000-12-27 Nestle Sa Nutritional composition for an immune condition
DE10105347A1 (de) * 2001-02-05 2002-08-22 Nutrinova Gmbh Sorbinsäurepräparat enthaltend Probiotika als Futtermittelzusatz in der Nutztieraufzucht
GB0125535D0 (en) 2001-10-24 2001-12-12 Microbiological Res Authority Mycobacterial genes down-regulated during latency
US6878373B2 (en) 2001-12-03 2005-04-12 Micropure Technologies, Inc. Probiotic composition containing Bacillus cereus RRRL B-30535
JP4111489B2 (ja) * 2002-05-23 2008-07-02 プリマハム株式会社 新規バクテリオシン
WO2004005492A2 (fr) * 2002-07-03 2004-01-15 Galina Gennadievna Alekhina Composition probiotique a base d'une souche d'enterocoques pour moyens de traitement et de prevention et procede de fabrication correspondant
EP1384483A1 (en) * 2002-07-23 2004-01-28 Nestec S.A. Probiotics for treatment of irritable bowel disease (IBS) through improvement of gut neuromuscular function
ITBO20020564A1 (it) 2002-09-06 2004-03-07 Alfa Wassermann Spa Bifidobatteri e preparazioni che li contengono.
JP2009538614A (ja) * 2006-05-28 2009-11-12 シプラ メドプロ リサーチ アンド デヴェロップメント (プロプライエタリー) リミテッド プロバイオティクス菌株及びこれに由来する抗菌性ペプチド

Also Published As

Publication number Publication date
IL250634A0 (en) 2017-03-30
EA200802409A1 (ru) 2009-10-30
KR20090023626A (ko) 2009-03-05
EP2021457A2 (en) 2009-02-11
WO2007138538A2 (en) 2007-12-06
NZ571619A (en) 2011-10-28
US20090297482A1 (en) 2009-12-03
IL195520A0 (en) 2011-08-01
US8444998B2 (en) 2013-05-21
NO20084577L (no) 2008-12-19
KR101521123B1 (ko) 2015-05-19
AP2841A (en) 2014-02-28
US7951385B2 (en) 2011-05-31
JP2009538614A (ja) 2009-11-12
US20110268703A1 (en) 2011-11-03
CN101454440A (zh) 2009-06-10
EA017558B1 (ru) 2013-01-30
WO2007138538A3 (en) 2008-04-17
AP2008004626A0 (en) 2008-10-31
CN101454440B (zh) 2013-05-29
AU2007266675B2 (en) 2012-09-06
EP2021457B1 (en) 2015-02-11
AU2007266675A1 (en) 2007-12-06

Similar Documents

Publication Publication Date Title
EP2021457B1 (en) Probiotic strain and antimicrobial peptide derived therefrom
Oh et al. Characterization and purification of a bacteriocin produced by a potential probiotic culture, Lactobacillus acidophilus 30SC
Jeronymo-Ceneviva et al. Probiotic properties of lactic acid bacteria isolated from water-buffalo mozzarella cheese
US6506389B2 (en) Adherence factors of non pathogenic microorganisms and applications thereof for screening microorganisms for specific probiotic properties; novel pharmaceutical compositions and food additives comprising such microorganisms and adherence factors
CA2280704A1 (en) Probiotic strains from lactobacillus salivarius and antimicrobial agents obtained therefrom
Todorov et al. Bacteriocin production and resistance to drugs are advantageous features for Lactobacillus acidophilus La-14, a potential probiotic strain
US6746672B2 (en) Isolated bifidobacteria that produce siderophores which inhibit growth of lactococcus lactis
Repally et al. Isolation, identification of Lactobacillus mucosae AN1 and its antilisterial peptide purification and characterization
Reid et al. Urogenital lactobacilli probiotics, reliability, and regulatory issues
US9963488B2 (en) Variants of the lantibiotic MU1140 and other lantibiotics with improved pharmacological properties and structural features
EP3484442A1 (en) Lantibiotic variants and uses thereof
JP2004519236A (ja) ビフィドバクテリウム由来の新規なプラスミド、これを利用した組換え発現ベクターおよび形質転換方法
Antonio et al. A Review of Lactic Acid Bacteria and their Bacteriocins: Classification, Biosynthesis, and Mechanism against Oral Pathogens
O'Sullivan Primary sources of probiotic cultures
Movsesyan et al. Properties and survival under simulated gastrointestinal conditions of lactic acid bacteria isolated from Armenian cheeses and matsuns
EP1148064A1 (en) Lactobacillus johnsonii bacteriocin, active against Helicobacter pylori
MX2008013429A (es) Cepas novedosas de enterococcus y streptococcus y bacteriocinas.
de Souza Vandenberghe et al. Bacteriocin Production by Lactic Acid Bacteria
Trivedi Isolation, Characterization and Assessment of Antimicrobial Potential of Urino-vaginal Microorganisms and their Application in the Development of Microbicides
Ladha Purification and characterization of antimicrobial substances from potent lactic acid bacteria isolated from rumen liquor of goat capra aegagrus hircus
Hossen Isolation of Probiotics, their Metabolites and Investigation of their Antibacterial Activities
Şanlıbaba Antibiotic Resistance and Virulence Factors of Enterococci
PANWAR Production and purification of native and recombinant surface layer protein (S-layer protein) from probiotic Lactobacillus spp.
Aissaoui et al. Study of Antimicrobial activity of Lactic Acid Bacteria fromdifferent origins: Production and Characterization of Bacteriocins
NAGAMANI THESIS SUBMITTED TO THE

Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued

Effective date: 20200831