CA2629522A1 - Gene therapy for renal failure - Google Patents
Gene therapy for renal failure Download PDFInfo
- Publication number
- CA2629522A1 CA2629522A1 CA002629522A CA2629522A CA2629522A1 CA 2629522 A1 CA2629522 A1 CA 2629522A1 CA 002629522 A CA002629522 A CA 002629522A CA 2629522 A CA2629522 A CA 2629522A CA 2629522 A1 CA2629522 A1 CA 2629522A1
- Authority
- CA
- Canada
- Prior art keywords
- bmp
- seq
- polypeptide
- group
- signal peptide
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/475—Growth factors; Growth regulators
- C07K14/51—Bone morphogenetic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/18—Growth factors; Growth regulators
- A61K38/1875—Bone morphogenic factor; Osteogenins; Osteogenic factor; Bone-inducing factor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
- A61K48/005—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy characterised by an aspect of the 'active' part of the composition delivered, i.e. the nucleic acid delivered
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Zoology (AREA)
- Epidemiology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Toxicology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Immunology (AREA)
- General Chemical & Material Sciences (AREA)
- Urology & Nephrology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US73645205P | 2005-11-14 | 2005-11-14 | |
| US60/736,452 | 2005-11-14 | ||
| PCT/US2006/044048 WO2007056614A1 (en) | 2005-11-14 | 2006-11-14 | Gene therapy for renal failure |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2629522A1 true CA2629522A1 (en) | 2007-05-18 |
Family
ID=37734130
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002629522A Abandoned CA2629522A1 (en) | 2005-11-14 | 2006-11-14 | Gene therapy for renal failure |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US7598364B2 (https=) |
| EP (4) | EP3147296A1 (https=) |
| JP (1) | JP2009515529A (https=) |
| CA (1) | CA2629522A1 (https=) |
| WO (1) | WO2007056614A1 (https=) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7771995B2 (en) * | 2005-11-14 | 2010-08-10 | Merial Limited | Plasmid encoding human BMP-7 |
| US20100291173A1 (en) * | 2006-09-05 | 2010-11-18 | Ed. Geistlich Soehne Ag Fuer Chemische Industrie | Method of improving renal function |
| US7794736B2 (en) * | 2006-11-21 | 2010-09-14 | Merial Limited | Canine Leishmania vaccine |
| US20120322861A1 (en) * | 2007-02-23 | 2012-12-20 | Barry John Byrne | Compositions and Methods for Treating Diseases |
| US7846428B2 (en) | 2007-10-05 | 2010-12-07 | Merial Limited | Articular cartilage gene therapy with recombinant vector encoding BMP-7 |
| KR20150020250A (ko) | 2012-06-19 | 2015-02-25 | 유니버시티 오브 플로리다 리서치 파운데이션, 인코포레이티드 | 당뇨병을 치료하기 위한 조성물 및 방법 |
| WO2014043518A1 (en) | 2012-09-14 | 2014-03-20 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Brachyury protein, non-poxvirus non-yeast vectors encoding brachyury protein, and their use |
| EP2951290B1 (en) | 2013-02-01 | 2017-11-29 | The United States of America, as represented by The Secretary, Department of Health and Human Services | Method for generating retinal pigment epithelium (rpe) cells from induced pluripotent stem cells (ipscs) |
| EP4137150A1 (en) | 2015-08-03 | 2023-02-22 | The United States of America, as represented by the Secretary, Department of Health and Human Services | Brachyury deletion mutants, non-yeast vectors encoding brachyury deletion mutants, and their use |
| AU2016318774B2 (en) | 2015-09-08 | 2022-08-18 | FUJIFILM Cellular Dynamics, Inc. | MACS-based purification of stem cell-derived retinal pigment epithelium |
| DK3347456T3 (da) | 2015-09-08 | 2024-02-19 | Us Health | Fremgangsmåde til reproducerbar differentiering af retinale pigmentepitelceller af klinisk kvalitet |
| AU2017290805B2 (en) | 2016-07-01 | 2023-11-16 | Research Development Foundation | Elimination of proliferating cells from stem cell-derived grafts |
| EP3491134B1 (en) | 2016-08-01 | 2023-10-11 | University of Pittsburgh - of The Commonwealth System of Higher Education | Human induced pluripotent stem cells for high efficiency genetic engineering |
| JP7248571B2 (ja) | 2016-10-05 | 2023-03-29 | フジフィルム セルラー ダイナミクス,インコーポレイテッド | MeCP2が破壊された誘導多能性幹細胞からの成熟系列の生成 |
| JP7222900B2 (ja) | 2016-11-09 | 2023-02-15 | ザ ユナイテッド ステイツ オブ アメリカ アズ リプリゼンテッド バイ ザ セクレタリー、デパートメント オブ ヘルス アンド ヒューマン サービシーズ | 細胞療法および創薬のための3d血管化ヒト眼組織 |
| CA3051442A1 (en) | 2017-02-14 | 2018-08-23 | Alejandro Soto-Gutierrez | Methods of engineering human induced pluripotent stem cells to produce liver tissue |
| SG11201909331UA (en) | 2017-04-18 | 2019-11-28 | Fujifilm Cellular Dynamics Inc | Antigen-specific immune effector cells |
| JP2021521792A (ja) | 2018-04-20 | 2021-08-30 | フジフィルム セルラー ダイナミクス,インコーポレイテッド | 眼球細胞の分化方法及びその使用 |
| WO2020086408A1 (en) | 2018-10-26 | 2020-04-30 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | A high-yield perfusion-based transient gene expression bioprocess |
| SG11202104401RA (en) | 2018-11-19 | 2021-05-28 | The United States Of America As Represented By The Secretary | Biodegradable tissue replacement implant and its use |
| MX2021006208A (es) | 2018-11-28 | 2021-10-01 | Univ Texas | Edición por multiplexación del genoma de células inmunitarias para mejorar la funcionalidad y resistencia al entorno supresor. |
| MX2021006393A (es) | 2018-11-29 | 2021-10-13 | Univ Texas | Metodos para expansion ex vivo de celulas exterminadoras naturales y uso de las mismas. |
| BR112022024064A2 (pt) | 2020-05-29 | 2023-01-31 | Fujifilm Cellular Dynamics Inc | Bicamada de epitélio pigmentado da retina e fotorreceptores e uso dos mesmos |
| US20230201267A1 (en) | 2020-05-29 | 2023-06-29 | FUJIFILM Cellular Dynamics, Inc. | Retinal pigmented epithelium and photoreceptor dual cell aggregates and methods of use thereof |
| KR20240011831A (ko) | 2021-05-26 | 2024-01-26 | 후지필름 셀룰러 다이내믹스, 인코포레이티드 | 만능 줄기 세포에서 유전자의 신속한 사일런싱을 방지하기 위한 방법 |
| CA3220602A1 (en) | 2021-05-28 | 2022-12-01 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods to generate macular, central and peripheral retinal pigment epithelial cells |
| EP4346928B1 (en) | 2021-05-28 | 2026-01-14 | The United States of America, as represented by The Secretary, Department of Health and Human Services | Biodegradable tissue scaffold with secondary matrix to host weakly adherent cells |
| CN118159646A (zh) | 2021-09-13 | 2024-06-07 | 富士胶片细胞动力公司 | 产生定向心脏祖细胞的方法 |
| CN119452078A (zh) | 2022-06-29 | 2025-02-14 | 富士胶片控股美国公司 | Ipsc来源的星形胶质细胞及其使用方法 |
| US20240139256A1 (en) | 2022-09-30 | 2024-05-02 | FUJIFILM Cellular Dynamics, Inc. | Methods for the production of cardiac fibroblasts |
| WO2024192329A1 (en) | 2023-03-16 | 2024-09-19 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Methods for producing stable human chondroctyes and their use for promoting cartillage growth and repair |
| WO2025245202A1 (en) | 2024-05-21 | 2025-11-27 | FUJIFILM Cellular Dynamics, Inc. | Particle counting and biomass measurements of aggregated cell compositions |
| US20260021201A1 (en) * | 2024-07-18 | 2026-01-22 | Wyvern Pharmaceuticals Inc. | Composition for regulating production of proteins |
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| US670A (en) | 1838-04-02 | Improved mode of forming raised surfaces for printing on paper, calico | ||
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-
2006
- 2006-11-14 EP EP16178703.1A patent/EP3147296A1/en not_active Ceased
- 2006-11-14 WO PCT/US2006/044048 patent/WO2007056614A1/en not_active Ceased
- 2006-11-14 CA CA002629522A patent/CA2629522A1/en not_active Abandoned
- 2006-11-14 EP EP06827775.5A patent/EP1951751B1/en active Active
- 2006-11-14 US US11/599,026 patent/US7598364B2/en active Active
- 2006-11-14 EP EP19167572.7A patent/EP3536704B1/en active Active
- 2006-11-14 JP JP2008540260A patent/JP2009515529A/ja active Pending
- 2006-11-14 EP EP10150052A patent/EP2186823A1/en not_active Ceased
-
2008
- 2008-11-19 US US12/273,931 patent/US7772205B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| WO2007056614A1 (en) | 2007-05-18 |
| EP3536704A1 (en) | 2019-09-11 |
| EP2186823A1 (en) | 2010-05-19 |
| EP1951751B1 (en) | 2017-11-01 |
| US7598364B2 (en) | 2009-10-06 |
| US20090082301A1 (en) | 2009-03-26 |
| EP3536704B1 (en) | 2021-08-25 |
| JP2009515529A (ja) | 2009-04-16 |
| US7772205B2 (en) | 2010-08-10 |
| EP3147296A1 (en) | 2017-03-29 |
| US20070155688A1 (en) | 2007-07-05 |
| EP1951751A1 (en) | 2008-08-06 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |
Effective date: 20150319 |