CA2619426C - Utilisation d'exendines pour le traitement du diabete et la reduction de la masse corporelle - Google Patents
Utilisation d'exendines pour le traitement du diabete et la reduction de la masse corporelle Download PDFInfo
- Publication number
- CA2619426C CA2619426C CA2619426A CA2619426A CA2619426C CA 2619426 C CA2619426 C CA 2619426C CA 2619426 A CA2619426 A CA 2619426A CA 2619426 A CA2619426 A CA 2619426A CA 2619426 C CA2619426 C CA 2619426C
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- Prior art keywords
- exendin
- ala
- gly
- agonist
- ser
- Prior art date
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/22—Hormones
- A61K38/26—Glucagons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
Abstract
La présente invention se rapporte à des méthodes permettant de réduire la masse corporelle, de modifier la constitution du corps humain, de traiter le diabète, de réduire HbA1c et de réduire la glycémie quotidienne moyenne, grâce à l'utilisation d'exendines, d'agonistes d'exendines ou d'agonistes d'analogues d'exendines.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US70960405P | 2005-08-19 | 2005-08-19 | |
US60/709,604 | 2005-08-19 | ||
US77921606P | 2006-03-03 | 2006-03-03 | |
US60/779,216 | 2006-03-03 | ||
PCT/US2006/032354 WO2007024700A2 (fr) | 2005-08-19 | 2006-08-18 | Methodes destinees a traiter le diabete et a reduire la masse corporelle |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2619426A1 CA2619426A1 (fr) | 2007-03-01 |
CA2619426C true CA2619426C (fr) | 2016-06-21 |
Family
ID=37772212
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2619426A Active CA2619426C (fr) | 2005-08-19 | 2006-08-18 | Utilisation d'exendines pour le traitement du diabete et la reduction de la masse corporelle |
Country Status (25)
Country | Link |
---|---|
US (7) | US20090239796A1 (fr) |
EP (3) | EP2347762B1 (fr) |
JP (2) | JP5693817B2 (fr) |
KR (1) | KR101059279B1 (fr) |
CN (1) | CN105056211A (fr) |
AU (2) | AU2006283517B2 (fr) |
BR (1) | BRPI0615358B8 (fr) |
CA (1) | CA2619426C (fr) |
CY (1) | CY1122010T1 (fr) |
DK (3) | DK2347762T3 (fr) |
ES (3) | ES2968190T3 (fr) |
FI (1) | FI3524261T3 (fr) |
HR (1) | HRP20150186T1 (fr) |
HU (2) | HUE064811T2 (fr) |
IL (2) | IL189607A (fr) |
LT (2) | LT2347762T (fr) |
MX (1) | MX2008002370A (fr) |
NZ (2) | NZ593461A (fr) |
PL (3) | PL1971362T3 (fr) |
PT (3) | PT3524261T (fr) |
RS (1) | RS53814B1 (fr) |
RU (1) | RU2421237C2 (fr) |
SG (1) | SG184730A1 (fr) |
SI (3) | SI1971362T1 (fr) |
WO (1) | WO2007024700A2 (fr) |
Families Citing this family (97)
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