CA2611809C - Differentiation of primate pluripotent stem cells to cardiomyocyte-lineage cells - Google Patents

Differentiation of primate pluripotent stem cells to cardiomyocyte-lineage cells Download PDF

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Publication number
CA2611809C
CA2611809C CA2611809A CA2611809A CA2611809C CA 2611809 C CA2611809 C CA 2611809C CA 2611809 A CA2611809 A CA 2611809A CA 2611809 A CA2611809 A CA 2611809A CA 2611809 C CA2611809 C CA 2611809C
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cells
bmp
cell
pluripotent stem
activin
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Expired - Fee Related
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CA2611809A
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French (fr)
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CA2611809A1 (en
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Joseph D. Gold
Mohammad Hassanipour
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Asterias Biotherapeutics Inc
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Asterias Biotherapeutics Inc
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0652Cells of skeletal and connective tissues; Mesenchyme
    • C12N5/0657Cardiomyocytes; Heart cells
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06Animal cells or tissues; Human cells or tissues
    • C12N5/0602Vertebrate cells
    • C12N5/0603Embryonic cells ; Embryoid bodies
    • C12N5/0606Pluripotent embryonic cells, e.g. embryonic stem cells [ES]
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    • C12N5/00Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2500/00Specific components of cell culture medium
    • C12N2500/90Serum-free medium, which may still contain naturally-sourced components
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/105Insulin-like growth factors [IGF]
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    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/155Bone morphogenic proteins [BMP]; Osteogenins; Osteogenic factor; Bone inducing factor
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    • C12N2501/00Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10Growth factors
    • C12N2501/16Activin; Inhibin; Mullerian inhibiting substance
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    • C12N2506/00Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/02Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells
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    • C12N2533/00Supports or coatings for cell culture, characterised by material
    • C12N2533/50Proteins
    • C12N2533/54Collagen; Gelatin

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
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CA2611809A 2005-06-22 2006-06-20 Differentiation of primate pluripotent stem cells to cardiomyocyte-lineage cells Expired - Fee Related CA2611809C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US69314105P 2005-06-22 2005-06-22
US60/693,141 2005-06-22
PCT/US2006/024060 WO2007002136A2 (en) 2005-06-22 2006-06-20 Differentiation of primate pluripotent stem cells to cardiomyocyte-lineage cells

Publications (2)

Publication Number Publication Date
CA2611809A1 CA2611809A1 (en) 2007-01-04
CA2611809C true CA2611809C (en) 2018-06-19

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CA2611809A Expired - Fee Related CA2611809C (en) 2005-06-22 2006-06-20 Differentiation of primate pluripotent stem cells to cardiomyocyte-lineage cells

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US (2) US9062289B2 (enExample)
EP (1) EP1910518B1 (enExample)
JP (2) JP5560393B2 (enExample)
KR (2) KR20130099253A (enExample)
CN (1) CN101228264B (enExample)
AU (1) AU2006262329B2 (enExample)
CA (1) CA2611809C (enExample)
GB (1) GB2441718B (enExample)
IL (1) IL187611A (enExample)
WO (1) WO2007002136A2 (enExample)

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AU2006262329A1 (en) 2007-01-04
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US20150284684A1 (en) 2015-10-08
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