CA2601623C - Methods and compositions for evaluating graft survival in a solid organ transplant recipient - Google Patents
Methods and compositions for evaluating graft survival in a solid organ transplant recipient Download PDFInfo
- Publication number
- CA2601623C CA2601623C CA2601623A CA2601623A CA2601623C CA 2601623 C CA2601623 C CA 2601623C CA 2601623 A CA2601623 A CA 2601623A CA 2601623 A CA2601623 A CA 2601623A CA 2601623 C CA2601623 C CA 2601623C
- Authority
- CA
- Canada
- Prior art keywords
- methods
- compositions
- graft survival
- organ transplant
- subject
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/106—Pharmacogenomics, i.e. genetic variability in individual responses to drugs and drug metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/118—Prognosis of disease development
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Immunology (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US66208305P | 2005-03-14 | 2005-03-14 | |
| US60/662,083 | 2005-03-14 | ||
| PCT/US2006/009134 WO2006099421A2 (en) | 2005-03-14 | 2006-03-13 | Methods and compositions for evaluating graft survival in a solid organ transplant recipient |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2601623A1 CA2601623A1 (en) | 2006-09-21 |
| CA2601623C true CA2601623C (en) | 2018-10-23 |
Family
ID=36992379
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2601623A Expired - Lifetime CA2601623C (en) | 2005-03-14 | 2006-03-13 | Methods and compositions for evaluating graft survival in a solid organ transplant recipient |
Country Status (5)
| Country | Link |
|---|---|
| US (2) | US7741038B2 (https=) |
| EP (2) | EP2604703B1 (https=) |
| JP (2) | JP2008537875A (https=) |
| CA (1) | CA2601623C (https=) |
| WO (1) | WO2006099421A2 (https=) |
Families Citing this family (52)
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| AU2002950779A0 (en) * | 2002-08-15 | 2002-09-12 | The Corporation Of The Trustees Of The Order Of The Sisters Of Mercy In Queensland | A method of immunomodulation |
| WO2005070086A2 (en) * | 2004-01-21 | 2005-08-04 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for determining a graft tolerant phenotype in a subject |
| EP2604703B1 (en) | 2005-03-14 | 2017-02-01 | The Board of Trustees of the Leland Stanford Junior University | Methods for evaluating graft survival in a solid organ transplant recipient |
| USRE46843E1 (en) | 2005-03-14 | 2018-05-15 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for evaluating graft survival in a solid organ transplant recipient |
| EP2066809A2 (en) * | 2006-08-28 | 2009-06-10 | Source Precision Medicine | Gene expression profiling for identification, monitoring and treatment of transplant rejection |
| US8003333B2 (en) * | 2007-09-28 | 2011-08-23 | Mayo Foundation For Medical Education And Research | Serum biomarkers for early detection of acute cellular rejection |
| EP2088205A1 (en) | 2008-02-11 | 2009-08-12 | Institut National De La Sante Et De La Recherche Medicale (Inserm) | PSMB10: A diagnosis marker and therapeutic target of chronic rejection. |
| ES2341419B1 (es) * | 2008-08-14 | 2011-05-03 | Hospital Clinic I Provincial De Barcelona | Wnt1 como biomarcador de daño renal. |
| WO2010021696A1 (en) * | 2008-08-18 | 2010-02-25 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for determining a graft tolerant phenotype in a subject |
| NZ610356A (en) * | 2008-08-28 | 2015-03-27 | Astute Medical Inc | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| CA2735590A1 (en) * | 2008-08-29 | 2010-03-04 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| NZ607703A (en) | 2008-10-21 | 2014-09-26 | Astute Medical Inc | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| WO2010048347A2 (en) * | 2008-10-21 | 2010-04-29 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| CN102264230B (zh) | 2008-11-10 | 2014-12-10 | 阿斯图特医药公司 | 用于诊断和预后肾损伤和肾衰竭的方法和组合物 |
| MX2011005379A (es) * | 2008-11-22 | 2011-06-09 | Astute Medical Inc | Metodos y composiciones para diagnosis y prognosis de lesion renal y falla renal. |
| ES2492498T3 (es) * | 2009-01-15 | 2014-09-09 | The Board Of Trustees Of The Leland Stanford Junior University | Panel de biomarcadores para el diagnóstico y la predicción de rechazo de injerto |
| US9229010B2 (en) | 2009-02-06 | 2016-01-05 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| WO2011006119A2 (en) | 2009-07-09 | 2011-01-13 | The Scripps Research Institute | Gene expression profiles associated with chronic allograft nephropathy |
| CA2770393A1 (en) | 2009-08-07 | 2011-02-10 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| EP2496942B1 (en) | 2009-11-07 | 2017-03-22 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| WO2011066380A1 (en) * | 2009-11-25 | 2011-06-03 | The Board Of Trustees Of The Leland Stanford Junior University | Biomarkers for the diagnosis of kidney graft rejection |
| EP2507630B1 (en) | 2009-12-02 | 2017-01-25 | The Board of Trustees of The Leland Stanford Junior University | Biomarkers for determining an allograft tolerant phenotype |
| JP5763098B2 (ja) | 2009-12-20 | 2015-08-12 | アスチュート メディカル,インコーポレイテッド | 腎損傷および腎不全の診断および予後診断のための方法ならびに組成物 |
| PT2666872T (pt) | 2010-02-05 | 2016-07-08 | Astute Medical Inc | Processos e composições para o diagnóstico e o prognóstico de lesões renais e de insuficiência renal |
| EP3070474A3 (en) | 2010-02-26 | 2016-12-07 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| WO2011119980A1 (en) * | 2010-03-25 | 2011-09-29 | The Board Of Trustees Of The Leland Stanford Junior University | Protein and gene biomarkers for rejection of organ transplants |
| GB201007454D0 (en) * | 2010-05-04 | 2010-06-16 | King S College London | Method of determining tolerance |
| NZ605698A (en) | 2010-06-23 | 2015-03-27 | Astute Medical Inc | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| EP2899545B1 (en) * | 2010-06-23 | 2018-08-22 | Astute Medical, Inc. | Methods for diagnosis and prognosis of renal injury and renal failure |
| US20130210043A1 (en) * | 2010-06-23 | 2013-08-15 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| IN2012MN02812A (https=) * | 2010-06-23 | 2015-05-22 | Astute Medical Inc | |
| WO2012106632A1 (en) * | 2011-02-03 | 2012-08-09 | The Board Of Trustees Of The Leland Stanford Junior University | Biomarkers for determining an allograft tolerant phenotype |
| US8962261B2 (en) | 2011-04-06 | 2015-02-24 | The Board Of Trustees Of The Leland Stanford Junior University | Autoantibody biomarkers for IGA nephropathy |
| CN103958662A (zh) * | 2011-10-24 | 2014-07-30 | 私募蛋白质体公司 | 用于疾病生物标记鉴定和样品质量评价的优选样品处理和加工方案的选择 |
| ES2734494T3 (es) | 2011-12-08 | 2019-12-10 | Astute Medical Inc | Métodos y usos para el diagnóstico de una lesión renal y de una insuficiencia renal |
| TR201807542T4 (tr) | 2013-01-17 | 2018-06-21 | Astute Medical Inc | Böbrek hasarı ve böbrek yetmezliği teşhisi ve prognozuna yönelik metotlar ve bileşimler. |
| CA2922746A1 (en) * | 2013-09-06 | 2015-03-12 | Immucor Gti Diagnostics, Inc. | Compositions and methods for diagnosis and prediction of solid organ graft rejection |
| CN103675300B (zh) * | 2014-01-03 | 2015-10-14 | 苏州工业园区为真生物医药科技有限公司 | Rbx1作为血清标志物的应用及其试剂盒 |
| US11104951B2 (en) | 2014-05-22 | 2021-08-31 | The Scripps Research Institute | Molecular signatures for distinguishing liver transplant rejections or injuries |
| US10443100B2 (en) | 2014-05-22 | 2019-10-15 | The Scripps Research Institute | Gene expression profiles associated with sub-clinical kidney transplant rejection |
| EP3465201A4 (en) | 2016-06-06 | 2020-08-26 | Astute Medical, Inc. | MANAGEMENT OF ACUTE KIDNEY DAMAGE USING INSULINOMIMETIC GROWTH FACTOR BINDING PROTEIN 7 AND TISSUE METALLOPROTEINASE 2 INHIBITOR |
| US10894960B2 (en) | 2016-08-30 | 2021-01-19 | Children's Hospital Medical Center | Compositions and methods for nucleic acid transfer |
| DK3510167T3 (da) * | 2016-09-08 | 2021-11-01 | Inst Nat Sante Rech Med | Fremgangsmåder og sammensætninger til forudsigelse af kronisk dysfunktion af lungeallotransplantation |
| US11346846B2 (en) | 2017-02-06 | 2022-05-31 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| US12411144B2 (en) | 2017-03-22 | 2025-09-09 | Children's Hospital Medical Center | Compositions and methods for treatment of lung function |
| WO2019107673A1 (ko) * | 2017-11-29 | 2019-06-06 | 서울대학교병원 | Abo 혈액형 부적합 이식시의 항체-매개성 거부반응의 모니터링을 위한 바이오마커 |
| CN111593113A (zh) * | 2020-05-21 | 2020-08-28 | 中国科学院大学宁波华美医院 | 一种基于急性排斥反应新机制的vegf基因结合位点检测方法 |
| US12247978B2 (en) * | 2020-08-05 | 2025-03-11 | Arizona Board Of Regents On Behalf Of Northern Arizona University | Compositions and methods for detection and treatment of coronavirus infection |
| WO2022031877A1 (en) * | 2020-08-05 | 2022-02-10 | Children's Hospital Medical Center | Compositions and methods for the treatment of bronchiolitis obliterans |
| CN111939272B (zh) * | 2020-08-21 | 2023-02-24 | 上海交通大学医学院附属第九人民医院 | Ccn1的用途 |
| CN116042848B (zh) * | 2021-10-28 | 2024-08-09 | 北京干细胞与再生医学研究院 | 一种通过血样检测判断动物体内存在移植物的方法 |
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| CN102124340B (zh) | 2008-06-02 | 2014-12-17 | 卫材R&D管理有限公司 | IgA肾病的检查方法和检查试剂盒 |
| WO2010021696A1 (en) | 2008-08-18 | 2010-02-25 | The Board Of Trustees Of The Leland Stanford Junior University | Methods and compositions for determining a graft tolerant phenotype in a subject |
| KR100928403B1 (ko) | 2008-10-01 | 2009-11-26 | 경북대학교 산학협력단 | 티지비엠 신증의 진단용 조성물 및 키트 |
| ES2492498T3 (es) | 2009-01-15 | 2014-09-09 | The Board Of Trustees Of The Leland Stanford Junior University | Panel de biomarcadores para el diagnóstico y la predicción de rechazo de injerto |
| US8734786B2 (en) | 2009-09-16 | 2014-05-27 | Northwestern University | Use of ECDI-fixed cell tolerance as a method for preventing allograft rejection |
| JP2013528799A (ja) | 2010-05-13 | 2013-07-11 | ユニバーシティ オブ メディスン アンド デンティストリー オブ ニュー ジャージー | 神経変性疾患の検知および診断のための診断用自己抗体プロファイル |
-
2006
- 2006-03-13 EP EP12197040.4A patent/EP2604703B1/en not_active Expired - Lifetime
- 2006-03-13 JP JP2008501966A patent/JP2008537875A/ja active Pending
- 2006-03-13 CA CA2601623A patent/CA2601623C/en not_active Expired - Lifetime
- 2006-03-13 EP EP06738217A patent/EP1869213A4/en not_active Withdrawn
- 2006-03-13 US US11/375,681 patent/US7741038B2/en not_active Ceased
- 2006-03-13 WO PCT/US2006/009134 patent/WO2006099421A2/en not_active Ceased
-
2012
- 2012-06-21 US US13/529,768 patent/USRE47057E1/en active Active
-
2015
- 2015-03-23 JP JP2015059131A patent/JP6178356B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| USRE47057E1 (en) | 2018-09-25 |
| EP2604703A3 (en) | 2013-09-18 |
| EP2604703B1 (en) | 2017-02-01 |
| EP1869213A4 (en) | 2008-05-14 |
| JP2015154774A (ja) | 2015-08-27 |
| CA2601623A1 (en) | 2006-09-21 |
| WO2006099421A3 (en) | 2007-03-01 |
| EP1869213A2 (en) | 2007-12-26 |
| EP2604703A2 (en) | 2013-06-19 |
| JP6178356B2 (ja) | 2017-08-09 |
| US20060246485A1 (en) | 2006-11-02 |
| US7741038B2 (en) | 2010-06-22 |
| JP2008537875A (ja) | 2008-10-02 |
| WO2006099421A2 (en) | 2006-09-21 |
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