CA2590257A1 - Novel adenoviruses, nucleic acids that code for the same and the use of said viruses - Google Patents
Novel adenoviruses, nucleic acids that code for the same and the use of said viruses Download PDFInfo
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- CA2590257A1 CA2590257A1 CA002590257A CA2590257A CA2590257A1 CA 2590257 A1 CA2590257 A1 CA 2590257A1 CA 002590257 A CA002590257 A CA 002590257A CA 2590257 A CA2590257 A CA 2590257A CA 2590257 A1 CA2590257 A1 CA 2590257A1
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- protein
- adenovirus
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Classifications
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- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
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- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10332—Use of virus as therapeutic agent, other than vaccine, e.g. as cytolytic agent
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10311—Mastadenovirus, e.g. human or simian adenoviruses
- C12N2710/10341—Use of virus, viral particle or viral elements as a vector
- C12N2710/10343—Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2840/00—Vectors comprising a special translation-regulating system
- C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron
- C12N2840/203—Vectors comprising a special translation-regulating system translation of more than one cistron having an IRES
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2840/00—Vectors comprising a special translation-regulating system
- C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron
- C12N2840/203—Vectors comprising a special translation-regulating system translation of more than one cistron having an IRES
- C12N2840/206—Vectors comprising a special translation-regulating system translation of more than one cistron having an IRES having multiple IRES
Landscapes
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- General Chemical & Material Sciences (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
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Applications Claiming Priority (5)
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| DE10353152.1 | 2003-11-14 | ||
| DE10353152 | 2003-11-14 | ||
| DE102004018117.9 | 2004-04-14 | ||
| DE102004018117 | 2004-04-14 | ||
| PCT/EP2004/012931 WO2005052143A2 (de) | 2003-11-14 | 2004-11-15 | Neue adenoviren, dafür codierende nukleinsäuren und deren verwendung |
Publications (1)
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| CA2590257A1 true CA2590257A1 (en) | 2005-06-09 |
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| CA002590257A Abandoned CA2590257A1 (en) | 2003-11-14 | 2004-11-15 | Novel adenoviruses, nucleic acids that code for the same and the use of said viruses |
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| EP (1) | EP1689446B1 (enExample) |
| JP (2) | JP2007511212A (enExample) |
| CA (1) | CA2590257A1 (enExample) |
| WO (1) | WO2005052143A2 (enExample) |
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| EP1506021B1 (de) | 2002-05-27 | 2019-05-01 | Per Sonne Holm | Verwendung von adenoviren und dafur kodierenden nukleinsäuren |
| CA2546178A1 (en) | 2003-11-14 | 2005-06-09 | Per Sonne Holm | New use of adenovirus and nucleic acids coding therefor |
| WO2006070024A2 (de) * | 2004-12-31 | 2006-07-06 | Per Sonne Holm | E1 -minus adenoviren und deren verwendung |
| SG158133A1 (en) | 2004-12-31 | 2010-01-29 | Sonne Holm | Method for reversing multiple resistance in animal cells |
| US20080213399A1 (en) | 2005-02-03 | 2008-09-04 | Topotarget Uk Limited | Combination Therapies Using Hdac Inhibitors |
| CA2606598C (en) * | 2005-05-13 | 2014-12-23 | Topotarget Uk Limited | Pharmaceutical formulations of hdac inhibitors |
| CA2627923C (en) * | 2005-11-10 | 2016-01-12 | Topotarget Uk Limited | Histone deacetylase (hdac) inhibitors (pxdlol) for the treatment of cancer |
| AU2006318652A1 (en) * | 2005-11-18 | 2007-05-31 | Gloucester Pharmaceuticals, Inc. | Metabolite derivatives of the HDAC inhibitor FK228 |
| WO2007145704A2 (en) | 2006-04-24 | 2007-12-21 | Gloucester Pharmaceuticals | Gemcitabine combination therapy |
| WO2007146730A2 (en) | 2006-06-08 | 2007-12-21 | Gloucester Pharmaceuticals | Deacetylase inhibitor therapy |
| AU2007342030B2 (en) * | 2006-12-29 | 2013-08-15 | Celgene Corporation | Romidepsin-based treatments for cancer |
| CN107090482A (zh) | 2006-12-29 | 2017-08-25 | 细胞基因公司 | 制备Romidepsin |
| JP5580043B2 (ja) * | 2007-04-27 | 2014-08-27 | オンコリスバイオファーマ株式会社 | 放射線増感増強剤 |
| CA2700173C (en) * | 2007-09-25 | 2016-10-11 | Topotarget Uk Limited | Methods of synthesis of certain hydroxamic acid compounds |
| ES2536208T3 (es) * | 2008-03-07 | 2015-05-21 | Onxeo Dk, Branch Of Onxeo S.A., France | Métodos de tratamiento que emplean infusión continua prolongada de Belinostat |
| GB0900555D0 (en) * | 2009-01-14 | 2009-02-11 | Topotarget As | New methods |
| ES2557812T3 (es) | 2009-03-02 | 2016-01-28 | The Regents Of The University Of California | Mutantes de E1a y E1b de adenovirus selectivos de tumor |
| CN103108648A (zh) | 2010-07-12 | 2013-05-15 | 细胞基因公司 | 罗米地辛固体形式及其用途 |
| US8859502B2 (en) | 2010-09-13 | 2014-10-14 | Celgene Corporation | Therapy for MLL-rearranged leukemia |
| AU2013202506B2 (en) | 2012-09-07 | 2015-06-18 | Celgene Corporation | Resistance biomarkers for hdac inhibitors |
| AU2013202507B9 (en) | 2012-11-14 | 2015-08-13 | Celgene Corporation | Inhibition of drug resistant cancer cells |
| NZ630311A (en) | 2013-12-27 | 2016-03-31 | Celgene Corp | Romidepsin formulations and uses thereof |
| CN109576231B (zh) * | 2017-09-28 | 2022-03-25 | 北京康万达医药科技有限公司 | 分离的重组溶瘤腺病毒、药物组合物及其在治疗肿瘤和/或癌症的药物中的用途 |
| KR20210031852A (ko) * | 2018-03-05 | 2021-03-23 | 클리니쿰 레히츠 데어 이자르 데어 테크니쉔 우니베르지테트 뮌헨 | 종양 세포 붕괴성 아데노바이러스와 cdk4/6 억제제의 조합물에 의한 종양의 치료 |
| CA3104948A1 (en) * | 2018-06-25 | 2020-01-02 | Ospedale San Raffaele S.R.L | Gene therapy |
| CN114269344A (zh) * | 2019-06-25 | 2022-04-01 | 微生物公司 | 用费洛西洛韦治疗或预防眼部感染的组合物和方法 |
| CN116179604B (zh) * | 2022-08-31 | 2025-08-26 | 上海锦斯生物技术有限公司 | 一种降低回复突变频率的重组5型腺病毒载体及其构建方法 |
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| CA2192442C (en) * | 1994-06-10 | 2007-09-25 | Imre Kovesdi | Complementary adenoviral vector systems and cell lines |
| US5998205A (en) * | 1994-11-28 | 1999-12-07 | Genetic Therapy, Inc. | Vectors for tissue-specific replication |
| DE19929569A1 (de) * | 1999-06-21 | 2000-12-28 | Holm Per Sonne | Mittel zur Behandlung maligner Erkrankungen unter Verwendung des Proteins YB-1 |
| US20030095989A1 (en) * | 2000-12-18 | 2003-05-22 | Irving John M. | Chimeric cytolytic viruses for cancer treatment |
| DE10150945A1 (de) * | 2001-10-16 | 2003-04-17 | Holm Per Sonne | Adenovirale Systeme und deren Anwendungen |
| US8263067B2 (en) | 2000-12-28 | 2012-09-11 | Per Sonne Holm | Adenoviral systems and the uses thereof |
| EP1506021B1 (de) * | 2002-05-27 | 2019-05-01 | Per Sonne Holm | Verwendung von adenoviren und dafur kodierenden nukleinsäuren |
| RU2393221C2 (ru) * | 2002-10-15 | 2010-06-27 | Пер Сонне ХОЛЬМ | Аденовирус с обращенной генной экспрессией и его применение |
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2004
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- 2004-11-15 JP JP2006538818A patent/JP2007511212A/ja active Pending
- 2004-11-15 CA CA002590257A patent/CA2590257A1/en not_active Abandoned
- 2004-11-15 EP EP04803146.2A patent/EP1689446B1/de not_active Expired - Lifetime
- 2004-11-15 US US10/579,543 patent/US20060270016A1/en not_active Abandoned
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2010
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2011
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Also Published As
| Publication number | Publication date |
|---|---|
| US20100297731A1 (en) | 2010-11-25 |
| WO2005052143A3 (de) | 2005-09-22 |
| EP1689446A2 (de) | 2006-08-16 |
| JP2011200234A (ja) | 2011-10-13 |
| WO2005052143A2 (de) | 2005-06-09 |
| US8586354B2 (en) | 2013-11-19 |
| US20060270016A1 (en) | 2006-11-30 |
| EP1689446B1 (de) | 2015-01-07 |
| JP2007511212A (ja) | 2007-05-10 |
| JP5618896B2 (ja) | 2014-11-05 |
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| US10300096B2 (en) | Use of adenoviruses and nucleic acids that code for said viruses | |
| US20170190752A1 (en) | E1-minus adenoviruses and use thereof | |
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| EEER | Examination request | ||
| FZDE | Discontinued |
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