CA2563185C - Sustained release formulations of a peptide or protein and a purified gallic acid ester - Google Patents
Sustained release formulations of a peptide or protein and a purified gallic acid ester Download PDFInfo
- Publication number
- CA2563185C CA2563185C CA2563185A CA2563185A CA2563185C CA 2563185 C CA2563185 C CA 2563185C CA 2563185 A CA2563185 A CA 2563185A CA 2563185 A CA2563185 A CA 2563185A CA 2563185 C CA2563185 C CA 2563185C
- Authority
- CA
- Canada
- Prior art keywords
- peptide
- acid ester
- gallic acid
- complex
- purified
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
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- 108090000765 processed proteins & peptides Proteins 0.000 title claims abstract description 109
- LNTHITQWFMADLM-UHFFFAOYSA-N anhydrous gallic acid Natural products OC(=O)C1=CC(O)=C(O)C(O)=C1 LNTHITQWFMADLM-UHFFFAOYSA-N 0.000 title claims abstract description 78
- -1 gallic acid ester Chemical class 0.000 title claims abstract description 73
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- 108090000623 proteins and genes Proteins 0.000 title claims abstract description 71
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- 238000013268 sustained release Methods 0.000 title claims abstract description 33
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- QJYNZEYHSMRWBK-NIKIMHBISA-N 1,2,3,4,6-pentakis-O-galloyl-beta-D-glucose Chemical group OC1=C(O)C(O)=CC(C(=O)OC[C@@H]2[C@H]([C@H](OC(=O)C=3C=C(O)C(O)=C(O)C=3)[C@@H](OC(=O)C=3C=C(O)C(O)=C(O)C=3)[C@H](OC(=O)C=3C=C(O)C(O)=C(O)C=3)O2)OC(=O)C=2C=C(O)C(O)=C(O)C=2)=C1 QJYNZEYHSMRWBK-NIKIMHBISA-N 0.000 claims abstract description 93
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Classifications
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- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
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- A61K38/00—Medicinal preparations containing peptides
- A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
- A61K38/08—Peptides having 5 to 11 amino acids
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
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- Chemical Kinetics & Catalysis (AREA)
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- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
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| US56524704P | 2004-04-23 | 2004-04-23 | |
| US60/565,247 | 2004-04-23 | ||
| PCT/US2005/014254 WO2005105057A1 (en) | 2004-04-23 | 2005-04-25 | Sustained release formulations |
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| CA2563185A1 CA2563185A1 (en) | 2005-11-10 |
| CA2563185C true CA2563185C (en) | 2010-04-20 |
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| CA2563185A Expired - Fee Related CA2563185C (en) | 2004-04-23 | 2005-04-25 | Sustained release formulations of a peptide or protein and a purified gallic acid ester |
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| PL (1) | PL1750683T3 (enExample) |
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| SI (1) | SI1750683T1 (enExample) |
| WO (1) | WO2005105057A1 (enExample) |
| ZA (1) | ZA200609401B (enExample) |
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| CN1997356A (zh) * | 2004-04-23 | 2007-07-11 | 安姆根有限公司 | 持续释放制剂 |
| US20050271726A1 (en) * | 2004-06-02 | 2005-12-08 | Albert Crum | Immune enhancing compositions and methods of use thereof |
| CA2589860A1 (en) | 2005-01-24 | 2006-08-03 | Amgen Inc. | Humanized anti-amyloid antibody |
| US7252834B2 (en) | 2005-04-25 | 2007-08-07 | Clemson University Research Foundation (Curf) | Elastin stabilization of connective tissue |
| NZ565535A (en) * | 2005-06-30 | 2011-03-31 | Ipsen Pharma Sas | GLP-1 pharmaceutical compositions |
| CA2642632A1 (en) * | 2006-02-15 | 2007-10-18 | Gammacan Ltd. | Immunoglobulins from vitiligo plasma for melanoma therapy |
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2005
- 2005-04-25 CN CNA2005800124592A patent/CN1997356A/zh active Pending
- 2005-04-25 SI SI200531678T patent/SI1750683T1/sl unknown
- 2005-04-25 KR KR1020067021346A patent/KR101201638B1/ko not_active Expired - Fee Related
- 2005-04-25 CN CN201410023256.4A patent/CN103920162B/zh not_active Expired - Fee Related
- 2005-04-25 CA CA2563185A patent/CA2563185C/en not_active Expired - Fee Related
- 2005-04-25 ES ES05742315T patent/ES2400687T3/es not_active Expired - Lifetime
- 2005-04-25 US US11/114,473 patent/US7323169B2/en not_active Expired - Fee Related
- 2005-04-25 PT PT57423154T patent/PT1750683E/pt unknown
- 2005-04-25 EP EP05742315A patent/EP1750683B1/en not_active Expired - Lifetime
- 2005-04-25 AU AU2005237542A patent/AU2005237542B2/en not_active Ceased
- 2005-04-25 PL PL05742315T patent/PL1750683T3/pl unknown
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- 2005-04-25 DK DK05742315.4T patent/DK1750683T3/da active
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- 2011-09-09 JP JP2011196884A patent/JP2012036194A/ja active Pending
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|---|---|
| WO2005105057A1 (en) | 2005-11-10 |
| CN1997356A (zh) | 2007-07-11 |
| JP5036533B2 (ja) | 2012-09-26 |
| DK1750683T3 (da) | 2013-04-15 |
| KR20070026457A (ko) | 2007-03-08 |
| US7732399B2 (en) | 2010-06-08 |
| CN103920162A (zh) | 2014-07-16 |
| JP2012046520A (ja) | 2012-03-08 |
| AU2005237542A1 (en) | 2005-11-10 |
| SI1750683T1 (sl) | 2013-04-30 |
| JP2007534698A (ja) | 2007-11-29 |
| US20050271722A1 (en) | 2005-12-08 |
| ZA200609401B (en) | 2008-05-28 |
| EP1750683A1 (en) | 2007-02-14 |
| PL1750683T3 (pl) | 2013-05-31 |
| ES2400687T3 (es) | 2013-04-11 |
| HK1200092A1 (en) | 2015-07-31 |
| IL178596A0 (en) | 2007-02-11 |
| EP1750683B1 (en) | 2013-01-09 |
| CN103920162B (zh) | 2017-07-11 |
| IL178596A (en) | 2012-06-28 |
| JP5829870B2 (ja) | 2015-12-09 |
| CA2563185A1 (en) | 2005-11-10 |
| US20070292506A1 (en) | 2007-12-20 |
| AU2005237542B2 (en) | 2009-12-17 |
| PT1750683E (pt) | 2013-01-25 |
| HK1103023A1 (en) | 2007-12-14 |
| US7323169B2 (en) | 2008-01-29 |
| KR101201638B1 (ko) | 2012-11-15 |
| JP2012036194A (ja) | 2012-02-23 |
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