CA2533838A1 - Improved ketoreductase polypeptides and related polynucleotides - Google Patents
Improved ketoreductase polypeptides and related polynucleotides Download PDFInfo
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- CA2533838A1 CA2533838A1 CA002533838A CA2533838A CA2533838A1 CA 2533838 A1 CA2533838 A1 CA 2533838A1 CA 002533838 A CA002533838 A CA 002533838A CA 2533838 A CA2533838 A CA 2533838A CA 2533838 A1 CA2533838 A1 CA 2533838A1
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
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- Engineering & Computer Science (AREA)
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- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
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| US49419503P | 2003-08-11 | 2003-08-11 | |
| US60/494,195 | 2003-08-11 | ||
| US54568204P | 2004-02-18 | 2004-02-18 | |
| US60/545,682 | 2004-02-18 | ||
| PCT/US2004/026655 WO2005017135A1 (en) | 2003-08-11 | 2004-08-11 | Improved ketoreductase polypeptides and related polynucleotides |
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| CA2533838A1 true CA2533838A1 (en) | 2005-02-24 |
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| EP (1) | EP1654354A1 (enExample) |
| JP (1) | JP2007502124A (enExample) |
| CA (1) | CA2533838A1 (enExample) |
| IL (1) | IL173191A (enExample) |
| WO (1) | WO2005017135A1 (enExample) |
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| MXPA06001718A (es) | 2003-08-11 | 2006-05-19 | Codexis Inc | Procedimiento enzimatico para la produccion de derivados de acido 3-hidroxibutirico 4-sustituido y esteres de acido carboxilico sustituido con ciano e hidroxi vecinales. |
| EP1908845A4 (en) * | 2005-07-20 | 2010-10-06 | Kaneka Corp | PROCESS FOR THE PRODUCTION OF 2- (AMINOMETHYL-N-SUBSTITUTED) 3-HYDROXYBUTYRIC ACID L ESTER WITH OPTICAL ACTIVITY |
| AT502395B1 (de) * | 2005-07-27 | 2007-03-15 | Iep Gmbh | Oxidoreduktasen zur stereoselektiven reduktion von ketoverbindungen |
| WO2008100251A1 (en) | 2007-02-13 | 2008-08-21 | Ls9, Inc. | Modified microorganism uses therefor |
| DE102006010994A1 (de) * | 2006-03-09 | 2007-09-13 | Wacker Chemie Ag | Verfahren zur enzymatischen Herstellung von chiralen Alkoholen |
| AT503486B1 (de) * | 2006-04-11 | 2008-05-15 | Iep Gmbh | Verfahren zur enantioselektiven reduktion von steroiden |
| US8110670B2 (en) | 2006-05-19 | 2012-02-07 | Ls9, Inc. | Enhanced production of fatty acid derivatives |
| CA2650773C (en) | 2006-05-19 | 2014-12-02 | Jay D. Keasling | Microorganisms transformed with acetyl-coa carboxylase and wax synthase for production of fatty acid derivatives |
| US20100242345A1 (en) | 2006-05-19 | 2010-09-30 | LS9, Inc | Production of fatty acids & derivatives thereof |
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| ATE518946T1 (de) * | 2007-02-08 | 2011-08-15 | Codexis Inc | Ketoreduktasen und anwendungen davon |
| BRPI0809345A2 (pt) | 2007-03-28 | 2014-10-07 | Ls9 Inc | Células recombinantes, composições produzidas por estas, métodos para produzir derivados de ácidos graxos em uma célula recombinante, para aumentar a produção de derivados de ácidos graxos em uma célula recombinante, construto recombinante, vetores, métodos para aumentar a produção de derivados de ácidos graxos em uma célula hospedeira de produção, para produzir derivados de ácidos graxos, derivados de ácidos graxos, composições de biocombustível. |
| CN101784669B (zh) | 2007-08-24 | 2015-02-18 | 科德克希思公司 | 用于(r)-3-羟基四氢噻吩的立体选择性制备的改善的酮还原酶多肽 |
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| DK2285958T3 (en) | 2008-06-13 | 2016-03-29 | Codexis Inc | Method for synthesizing polynucleotides |
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