CA2492789C - Procede de preparation de microcapsules pharmaceutiques ayant un meilleur masquage du gout et une vitesse de dissolution elevee - Google Patents
Procede de preparation de microcapsules pharmaceutiques ayant un meilleur masquage du gout et une vitesse de dissolution elevee Download PDFInfo
- Publication number
- CA2492789C CA2492789C CA2492789A CA2492789A CA2492789C CA 2492789 C CA2492789 C CA 2492789C CA 2492789 A CA2492789 A CA 2492789A CA 2492789 A CA2492789 A CA 2492789A CA 2492789 C CA2492789 C CA 2492789C
- Authority
- CA
- Canada
- Prior art keywords
- drug
- coating
- microcapsules
- process according
- acrylic polymer
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
- B01J13/02—Making microcapsules or microballoons
- B01J13/06—Making microcapsules or microballoons by phase separation
- B01J13/08—Simple coacervation, i.e. addition of highly hydrophilic material
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J13/00—Colloid chemistry, e.g. the production of colloidal materials or their solutions, not otherwise provided for; Making microcapsules or microballoons
- B01J13/02—Making microcapsules or microballoons
- B01J13/06—Making microcapsules or microballoons by phase separation
Abstract
Cette invention se rapporte à un procédé servant à produire des microcapsules contenant un médicament et comportant une couche d'éthylcellulose et une couche d'un polymère acrylique, ainsi qu'aux microcapsules ainsi produites.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/EP2002/007961 WO2004009058A1 (fr) | 2002-07-17 | 2002-07-17 | Procede pour la preparation de microcapsules pharmaceutiques avec masquage ameliore du gout et taux de dissolution eleve |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2492789A1 CA2492789A1 (fr) | 2004-01-29 |
CA2492789C true CA2492789C (fr) | 2012-07-03 |
Family
ID=30470213
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2492789A Expired - Fee Related CA2492789C (fr) | 2002-07-17 | 2002-07-17 | Procede de preparation de microcapsules pharmaceutiques ayant un meilleur masquage du gout et une vitesse de dissolution elevee |
Country Status (6)
Country | Link |
---|---|
US (1) | US20050269722A1 (fr) |
EP (1) | EP1534251A1 (fr) |
JP (1) | JP4357422B2 (fr) |
AU (1) | AU2002368090A1 (fr) |
CA (1) | CA2492789C (fr) |
WO (1) | WO2004009058A1 (fr) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8071128B2 (en) | 1996-06-14 | 2011-12-06 | Kyowa Hakko Kirin Co., Ltd. | Intrabuccally rapidly disintegrating tablet and a production method of the tablets |
US9358214B2 (en) | 2001-10-04 | 2016-06-07 | Adare Pharmaceuticals, Inc. | Timed, sustained release systems for propranolol |
US8367111B2 (en) | 2002-12-31 | 2013-02-05 | Aptalis Pharmatech, Inc. | Extended release dosage forms of propranolol hydrochloride |
US8747895B2 (en) | 2004-09-13 | 2014-06-10 | Aptalis Pharmatech, Inc. | Orally disintegrating tablets of atomoxetine |
US9884014B2 (en) | 2004-10-12 | 2018-02-06 | Adare Pharmaceuticals, Inc. | Taste-masked pharmaceutical compositions |
CA2584957C (fr) | 2004-10-21 | 2015-08-25 | Eurand Pharmaceuticals Limited | Compositions pharmaceutiques a saveur masquee avec substances porogenes gastrosolubles |
US9161918B2 (en) | 2005-05-02 | 2015-10-20 | Adare Pharmaceuticals, Inc. | Timed, pulsatile release systems |
US20070098746A1 (en) * | 2005-11-02 | 2007-05-03 | Nichols William M | Multi-layered coating technology for taste masking |
WO2011067667A2 (fr) | 2009-12-02 | 2011-06-09 | Eurand Pharmaceuticals Limited | Microcapsules de fexofénadine et compositions les contenant |
CN103655483A (zh) * | 2012-09-26 | 2014-03-26 | 扬州市星斗药业有限公司 | 一种含有替比培南的颗粒及其制备方法 |
ES2876014T3 (es) * | 2012-12-28 | 2021-11-11 | I P S Int Products & Services S R L | Preparación sólida oral con liberación modificada |
JP6572244B2 (ja) | 2014-02-25 | 2019-09-04 | オービス バイオサイエンシズ, インク.Orbis Biosciences, Inc. | 味覚マスキング薬製剤 |
CN103893150B (zh) * | 2014-03-28 | 2016-06-08 | 北京联合大学 | 一种青霉素v钾微囊及其制备方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3900811A1 (de) * | 1989-01-13 | 1990-07-19 | Kali Chemie Pharma Gmbh | Neue arzneiform |
DE4200821A1 (de) * | 1992-01-15 | 1993-07-22 | Bayer Ag | Geschmacksmaskierte pharmazeutische mittel |
US6197347B1 (en) * | 1998-06-29 | 2001-03-06 | Andrx Pharmaceuticals, Inc. | Oral dosage for the controlled release of analgesic |
EP1133282A4 (fr) * | 1998-11-25 | 2006-03-29 | Cima Labs Inc | Systeme d'enrobage a liberation rapide masquant le gout |
FR2795962B1 (fr) * | 1999-07-08 | 2003-05-09 | Prographarm Laboratoires | Procede de fabrication de granules enrobes a gout masque et liberation immediate du principe actif |
US6419956B1 (en) * | 1999-12-30 | 2002-07-16 | Ancile Pharmaceuticals | Odor-masking coating for a pharmaceutical preparation |
US6451345B1 (en) * | 2000-01-20 | 2002-09-17 | Eurand Pharmaceuticals Ltd. | Functional coating of linezolid microcapsules for taste-masking and associated formulation for oral administration |
-
2002
- 2002-07-17 EP EP02807606A patent/EP1534251A1/fr not_active Withdrawn
- 2002-07-17 AU AU2002368090A patent/AU2002368090A1/en not_active Abandoned
- 2002-07-17 US US10/521,598 patent/US20050269722A1/en not_active Abandoned
- 2002-07-17 WO PCT/EP2002/007961 patent/WO2004009058A1/fr not_active Application Discontinuation
- 2002-07-17 CA CA2492789A patent/CA2492789C/fr not_active Expired - Fee Related
- 2002-07-17 JP JP2004522144A patent/JP4357422B2/ja not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
WO2004009058A1 (fr) | 2004-01-29 |
US20050269722A1 (en) | 2005-12-08 |
JP4357422B2 (ja) | 2009-11-04 |
JP2005537270A (ja) | 2005-12-08 |
EP1534251A1 (fr) | 2005-06-01 |
CA2492789A1 (fr) | 2004-01-29 |
AU2002368090A1 (en) | 2004-02-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |
Effective date: 20200831 |