CA2487475A1 - Procede de formation d'une liaison carbone-carbone ou carbone-heteroatome - Google Patents

Procede de formation d'une liaison carbone-carbone ou carbone-heteroatome Download PDF

Info

Publication number
CA2487475A1
CA2487475A1 CA002487475A CA2487475A CA2487475A1 CA 2487475 A1 CA2487475 A1 CA 2487475A1 CA 002487475 A CA002487475 A CA 002487475A CA 2487475 A CA2487475 A CA 2487475A CA 2487475 A1 CA2487475 A1 CA 2487475A1
Authority
CA
Canada
Prior art keywords
group
formula
groups
ligand
represent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002487475A
Other languages
English (en)
French (fr)
Inventor
Marc Taillefer
Henri-Jean Cristau
Pascal-Philippe Cellier
Jean-Francis Spindler
Armelle Ouali
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhodia Chimie SAS
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR0206717A external-priority patent/FR2840303B1/fr
Application filed by Individual filed Critical Individual
Publication of CA2487475A1 publication Critical patent/CA2487475A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/64—One oxygen atom attached in position 2 or 6
    • C07D213/643—2-Phenoxypyridines; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24—Oxygen or sulfur atoms
    • C07D207/26—2-Pyrrolidones
    • C07D207/263—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms
    • C07D207/267—2-Pyrrolidones with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to other ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D207/323—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms directly attached to the ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/62—Oxygen or sulfur atoms
    • C07D213/63—One oxygen atom
    • C07D213/64—One oxygen atom attached in position 2 or 6
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C07D233/58—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Indole Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pyrrole Compounds (AREA)
  • Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
CA002487475A 2002-05-31 2003-06-02 Procede de formation d'une liaison carbone-carbone ou carbone-heteroatome Abandoned CA2487475A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR0206717A FR2840303B1 (fr) 2002-05-31 2002-05-31 Procede d'arylation ou de vinylation ou d'alcylynation d'un compose nucleophile
FR02/6717 2002-05-31
PCT/FR2003/001647 WO2003101966A1 (fr) 2002-05-31 2003-06-02 Procede de formation d'une liaison carbone-carbone ou carbone-heteroatome

Publications (1)

Publication Number Publication Date
CA2487475A1 true CA2487475A1 (fr) 2003-12-11

Family

ID=34089839

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002487475A Abandoned CA2487475A1 (fr) 2002-05-31 2003-06-02 Procede de formation d'une liaison carbone-carbone ou carbone-heteroatome

Country Status (6)

Country Link
US (1) US20050234239A1 (https=)
EP (1) EP1509502A1 (https=)
JP (1) JP2006501159A (https=)
CN (1) CN1668595A (https=)
AU (1) AU2003255620A1 (https=)
CA (1) CA2487475A1 (https=)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2007089267A1 (en) 2006-02-03 2007-08-09 Jr Chem, Llc Anti-aging treatment using copper and zinc compositions
US7687650B2 (en) 2006-02-03 2010-03-30 Jr Chem, Llc Chemical compositions and methods of making them
US7897800B2 (en) 2006-02-03 2011-03-01 Jr Chem, Llc Chemical compositions and methods of making them
US7867522B2 (en) 2006-09-28 2011-01-11 Jr Chem, Llc Method of wound/burn healing using copper-zinc compositions
FR2915200B1 (fr) 2007-04-20 2009-07-03 Centre Nat Rech Scient Procede de preparation de ligands de type phosphines butadieniques,leurs complexes avec le cuivre,et leurs applications en catalyse
US8273791B2 (en) 2008-01-04 2012-09-25 Jr Chem, Llc Compositions, kits and regimens for the treatment of skin, especially décolletage
BRPI0923527A2 (pt) * 2008-12-24 2016-08-09 Syngenta Ltd métodos de preparo de fungicidas
CA2750636C (en) 2009-01-23 2017-07-25 Jr Chem, Llc Rosacea treatments and kits for performing them
US8952057B2 (en) 2011-01-11 2015-02-10 Jr Chem, Llc Compositions for anorectal use and methods for treating anorectal disorders
CN102432523B (zh) * 2011-09-21 2013-11-06 温州大学 一种3-羟基-3-芳基吲哚-2-酮衍生物的合成方法
CN102558056B (zh) * 2012-01-06 2014-04-09 湖南方盛制药股份有限公司 塞来昔布及其制备方法
CN104592086B (zh) * 2015-01-31 2017-06-06 台州学院 一种通过铜盐催化制备吲哚类化合物的方法
CN109912457A (zh) * 2019-05-06 2019-06-21 浙江中山化工集团股份有限公司 一种2,6-二乙基-4-甲基苯基丙二腈的制备方法
CN111484453B (zh) * 2020-04-13 2023-05-05 福建海西新药创制股份有限公司 一种塞来昔布的合成方法
CN114149364A (zh) * 2021-12-21 2022-03-08 无锡捷化医药科技有限公司 一种n-(6-甲氧基吡啶-3-基)-3-甲基吡啶-2-磺酰胺的制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4098867B2 (ja) * 1998-01-09 2008-06-11 富士フイルムファインケミカルズ株式会社 アリールアミンの製造方法
US6541639B2 (en) * 2000-07-26 2003-04-01 Bristol-Myers Squibb Pharma Company Efficient ligand-mediated Ullmann coupling of anilines and azoles
US6759554B2 (en) * 2001-04-24 2004-07-06 Massachusetts Institute Of Technology Copper-catalyzed formation of carbon-heteroatom and carbon-carbon bonds

Also Published As

Publication number Publication date
EP1509502A1 (fr) 2005-03-02
JP2006501159A (ja) 2006-01-12
US20050234239A1 (en) 2005-10-20
AU2003255620A1 (en) 2003-12-19
CN1668595A (zh) 2005-09-14

Similar Documents

Publication Publication Date Title
WO2003101966A1 (fr) Procede de formation d'une liaison carbone-carbone ou carbone-heteroatome
Petrassi et al. The copper-mediated cross-coupling of phenylboronic acids and N-hydroxyphthalimide at room temperature: synthesis of aryloxyamines
Yoshida et al. Oxidative carboxylation of arylaldehydes with water by a sulfoxylalkyl-substituted N-heterocyclic carbene catalyst
CA2487475A1 (fr) Procede de formation d'une liaison carbone-carbone ou carbone-heteroatome
US8058477B2 (en) Process for the synthesis of arylamines from the reaction of an aromatic compound with ammonia or a metal amide
JP6518242B2 (ja) ハロゲン化されたビフェニルアニリドおよびビフェニルアニリンの改善された製造方法
U Tekale et al. Application progress of recent advances in some copper catalyzed coupling reactions
JP5355393B2 (ja) ハロベンゼン誘導体からアルキルアニリドを製造するための方法
CA2470141A1 (fr) Procede de formation d'une liaison carbone-carbone ou carbone-heteroatome
Daley et al. Palladium-catalyzed salt-free double decarboxylative aryl allylation
EP2197829A2 (fr) Procede de synthese d'arylamines
WO2005095307A1 (fr) Procede de formation d'une liaison carbone-carbone comprenant une reaction d’un arenediazoether
WO2001038291A2 (fr) Procede de preparation d'un compose polyaromatique
CN114920666A (zh) 一种铑催化的芳基硼酸和二腈衍生物合成邻烯基苯腈衍生物的方法
WO2005023731A2 (fr) Procede de formation d'une liaison carbone-carbone ou carbone-heteroatome.
EP2527350B1 (fr) Procédé de préparation de ligands de type phosphines butadiéniques, leurs complexes avec le cuivre, et leurs applications en catalyse
WO2002006187A1 (fr) Procede de preparation d'un compose polyaromatique
FR2854890A1 (fr) Procede de formation d'une liaison carbone-heteroatome
Das Sustainable Strategies in Transition Metal Catalysis for Small Molecule Synthesis
EP1314727B1 (fr) Synthèse directe de sels quaternaires de phenanthridinium
FR2801884A1 (fr) Procede de preparation d'un compose polyaromatique
WO2011101599A1 (fr) Procédé de préparation de composés chimiques d'intérêt par substitution nucléophile aromatique
Glover Development of an asymmetric intermolecular Stetter reaction and organocatalyst design

Legal Events

Date Code Title Description
FZDE Discontinued