CA2487167A1 - Combination of a dpp iv inhibitor and a cardiovascular compound - Google Patents
Combination of a dpp iv inhibitor and a cardiovascular compound Download PDFInfo
- Publication number
- CA2487167A1 CA2487167A1 CA002487167A CA2487167A CA2487167A1 CA 2487167 A1 CA2487167 A1 CA 2487167A1 CA 002487167 A CA002487167 A CA 002487167A CA 2487167 A CA2487167 A CA 2487167A CA 2487167 A1 CA2487167 A1 CA 2487167A1
- Authority
- CA
- Canada
- Prior art keywords
- pharmaceutically acceptable
- acceptable salt
- inhibitor
- hypertension
- dpp
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
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Landscapes
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| PCT/EP2003/005639 WO2003099279A1 (en) | 2002-05-29 | 2003-05-28 | Combination of a dpp iv inhibitor and a cardiovascular compound |
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| CN100402026C (zh) * | 2002-06-03 | 2008-07-16 | 诺瓦提斯公司 | 取代的氰基吡咯烷和含有它们的组合制剂用于治疗高脂血症和相关疾病的用途 |
| US7407955B2 (en) | 2002-08-21 | 2008-08-05 | Boehringer Ingelheim Pharma Gmbh & Co., Kg | 8-[3-amino-piperidin-1-yl]-xanthines, the preparation thereof and their use as pharmaceutical compositions |
| US20040242568A1 (en) | 2003-03-25 | 2004-12-02 | Syrrx, Inc. | Dipeptidyl peptidase inhibitors |
| US20040214804A1 (en) * | 2003-04-25 | 2004-10-28 | Pharmacia Corporation | Combination of an aldosterone receptor antagonist and an anti-obesity agent |
| JP2007511467A (ja) | 2003-05-14 | 2007-05-10 | タケダ サン ディエゴ インコーポレイテッド | ジペプチジルペプチダーゼインヒビター |
| MXPA06001601A (es) | 2003-08-13 | 2006-08-25 | Takeda Pharmaceutical | Derivados de 4-pirimidona y su uso como inhibidores de dipeptidilpeptidasa. |
| US7678909B1 (en) | 2003-08-13 | 2010-03-16 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
| US7169926B1 (en) | 2003-08-13 | 2007-01-30 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
| WO2005026148A1 (en) | 2003-09-08 | 2005-03-24 | Takeda San Diego, Inc. | Dipeptidyl peptidase inhibitors |
| RU2385723C2 (ru) * | 2003-11-17 | 2010-04-10 | Новартис Аг | Применение ингибиторов дипептидилпептидазы iv |
| US7501426B2 (en) | 2004-02-18 | 2009-03-10 | Boehringer Ingelheim International Gmbh | 8-[3-amino-piperidin-1-yl]-xanthines, their preparation and their use as pharmaceutical compositions |
| US7732446B1 (en) | 2004-03-11 | 2010-06-08 | Takeda Pharmaceutical Company Limited | Dipeptidyl peptidase inhibitors |
| CN102079743B (zh) | 2004-03-15 | 2020-08-25 | 武田药品工业株式会社 | 二肽基肽酶抑制剂 |
| RU2426532C2 (ru) * | 2004-03-17 | 2011-08-20 | Новартис Аг | Применение органических соединений |
| WO2005099695A1 (en) * | 2004-04-19 | 2005-10-27 | Novartis Ag | Drug delivery systems for the prevention and treatment of vascular diseases |
| US7687638B2 (en) | 2004-06-04 | 2010-03-30 | Takeda San Diego, Inc. | Dipeptidyl peptidase inhibitors |
| WO2006000564A1 (en) * | 2004-06-23 | 2006-01-05 | Solvay Pharmaceuticals Gmbh | Pharmaceutical compositions comprising nep-inhibitors, inhibitors of the endogenous endothelin producing system and at1-receptor antagonists |
| WO2006019965A2 (en) | 2004-07-16 | 2006-02-23 | Takeda San Diego, Inc. | Dipeptidyl peptidase inhibitors |
| RU2407523C2 (ru) * | 2004-10-08 | 2010-12-27 | Новартис Аг | Применение ингибиторов ренина для профилактики или лечения диастолической дисфункции или диастолической сердечной недостаточности |
| DE102004054054A1 (de) | 2004-11-05 | 2006-05-11 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verfahren zur Herstellung chiraler 8-(3-Amino-piperidin-1-yl)-xanthine |
| JP2008524331A (ja) | 2004-12-21 | 2008-07-10 | 武田薬品工業株式会社 | ジペプチジルペプチダーゼ阻害剤 |
| NZ555334A (en) | 2004-12-24 | 2010-05-28 | Spinifex Pharm Pty Ltd | Method of treatment or prophylaxis of a neuropathic condition using AT2 receptor antagonist |
| DOP2006000008A (es) | 2005-01-10 | 2006-08-31 | Arena Pharm Inc | Terapia combinada para el tratamiento de la diabetes y afecciones relacionadas y para el tratamiento de afecciones que mejoran mediante un incremento de la concentración sanguínea de glp-1 |
| MY146830A (en) * | 2005-02-11 | 2012-09-28 | Novartis Ag | Combination of organic compounds |
| GB0503062D0 (en) * | 2005-02-14 | 2005-03-23 | Novartis Ag | Combination of organic compounds |
| MX2007011453A (es) | 2005-04-22 | 2008-02-12 | Alantos Pharmaceuticals Holding Inc | Inhibidores de la dipeptidil peptidasa-iv. |
| WO2006137222A1 (ja) * | 2005-06-24 | 2006-12-28 | Tokyo Medical And Dental University | 薬剤溶出速度制御方法、及び薬剤溶出性ステント被膜用組成物 |
| DE102005035891A1 (de) | 2005-07-30 | 2007-02-08 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | 8-(3-Amino-piperidin-1-yl)-xanthine, deren Herstellung und deren Verwendung als Arzneimittel |
| US20130131007A1 (en) | 2005-09-07 | 2013-05-23 | Bebaas, Inc. | Vitamin b12 compositions |
| NZ566799A (en) | 2005-09-14 | 2011-04-29 | Takeda Pharmaceutical | Dipeptidyl peptidase inhibitors for treating diabetes |
| WO2007035629A2 (en) | 2005-09-16 | 2007-03-29 | Takeda Pharmaceutical Company Limited | Process for the preparation of pyrimidinedione derivatives |
| US20070196510A1 (en) * | 2006-02-17 | 2007-08-23 | Gerber Michael J | Method for treating resistant hypertension |
| JP5230595B2 (ja) | 2006-03-20 | 2013-07-10 | スピニフェクス ファーマシューティカルズ ピーティーワイ リミテッド | 炎症性疼痛の治療または予防の方法 |
| PE20071221A1 (es) | 2006-04-11 | 2007-12-14 | Arena Pharm Inc | Agonistas del receptor gpr119 en metodos para aumentar la masa osea y para tratar la osteoporosis y otras afecciones caracterizadas por masa osea baja, y la terapia combinada relacionada a estos agonistas |
| EP1852108A1 (en) | 2006-05-04 | 2007-11-07 | Boehringer Ingelheim Pharma GmbH & Co.KG | DPP IV inhibitor formulations |
| BRPI0711558A2 (pt) | 2006-05-04 | 2011-11-08 | Boeringer Ingelheim Internat Gmbh | polimorfos |
| PE20080251A1 (es) | 2006-05-04 | 2008-04-25 | Boehringer Ingelheim Int | Usos de inhibidores de dpp iv |
| US8324383B2 (en) | 2006-09-13 | 2012-12-04 | Takeda Pharmaceutical Company Limited | Methods of making polymorphs of benzoate salt of 2-[[6-[(3R)-3-amino-1-piperidinyl]-3,4-dihydro-3-methyl-2,4-dioxo-1(2H)-pyrimidinyl]methyl]-benzonitrile |
| TW200838536A (en) | 2006-11-29 | 2008-10-01 | Takeda Pharmaceutical | Polymorphs of succinate salt of 2-[6-(3-amino-piperidin-1-yl)-3-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-ylmethy]-4-fluor-benzonitrile and methods of use therefor |
| WO2008094689A2 (en) * | 2007-02-01 | 2008-08-07 | Nephrogen, Llc | Potentiation of stem cell homing and treatment of organ dysfunction or organ failure |
| US8093236B2 (en) | 2007-03-13 | 2012-01-10 | Takeda Pharmaceuticals Company Limited | Weekly administration of dipeptidyl peptidase inhibitors |
| CA2697057A1 (en) * | 2007-08-22 | 2009-02-26 | Gilead Colorado, Inc. | Therapy for complications of diabetes |
| EP2062874B1 (en) | 2007-11-20 | 2014-12-17 | KRKA, tovarna zdravil, d.d., Novo mesto | Process and intermediates for the preparation of aliskiren |
| PE20140960A1 (es) | 2008-04-03 | 2014-08-15 | Boehringer Ingelheim Int | Formulaciones que comprenden un inhibidor de dpp4 |
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| US5175187A (en) * | 1989-03-06 | 1992-12-29 | Soorianarain Baligadoo | Synergistic compositions for the treatment of coronary insufficiency and methods of use thereof |
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| ATE385421T1 (de) * | 2000-01-21 | 2008-02-15 | Novartis Pharma Gmbh | Zusammensetzungen bestehend aus dipeptidylpeptidase-iv inhibitoren und antidiabetica |
| GB0014969D0 (en) * | 2000-06-19 | 2000-08-09 | Smithkline Beecham Plc | Novel method of treatment |
| US20020037829A1 (en) * | 2000-08-23 | 2002-03-28 | Aronson Peter S. | Use of DPPIV inhibitors as diuretic and anti-hypertensive agents |
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2003
- 2003-05-28 CN CNA2009100075473A patent/CN101518650A/zh active Pending
- 2003-05-28 AU AU2003242593A patent/AU2003242593A1/en not_active Abandoned
- 2003-05-28 WO PCT/EP2003/005639 patent/WO2003099279A1/en not_active Ceased
- 2003-05-28 NZ NZ548971A patent/NZ548971A/en not_active IP Right Cessation
- 2003-05-28 US US10/515,864 patent/US20060074058A1/en not_active Abandoned
- 2003-05-28 NZ NZ536758A patent/NZ536758A/en not_active IP Right Cessation
- 2003-05-28 EP EP03755149A patent/EP1511484A1/en not_active Withdrawn
- 2003-05-28 JP JP2004506803A patent/JP2005532330A/ja not_active Withdrawn
- 2003-05-28 CA CA002487167A patent/CA2487167A1/en not_active Abandoned
- 2003-05-28 CN CNA038121840A patent/CN1655786A/zh active Pending
- 2003-05-28 RU RU2004139025/15A patent/RU2336876C2/ru not_active IP Right Cessation
- 2003-05-28 PL PL03372571A patent/PL372571A1/xx not_active Application Discontinuation
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- 2003-05-28 MX MXPA04011785A patent/MXPA04011785A/es active IP Right Grant
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Also Published As
| Publication number | Publication date |
|---|---|
| US20070293474A1 (en) | 2007-12-20 |
| CN101518650A (zh) | 2009-09-02 |
| GB0212412D0 (en) | 2002-07-10 |
| CO5621286A2 (es) | 2006-03-31 |
| JP2010090173A (ja) | 2010-04-22 |
| CN1655786A (zh) | 2005-08-17 |
| NO20045557L (no) | 2005-02-28 |
| BR0311397A (pt) | 2005-03-15 |
| RU2008119956A (ru) | 2009-11-27 |
| ZA200408990B (en) | 2006-07-26 |
| NZ536758A (en) | 2007-02-23 |
| AU2003242593A1 (en) | 2003-12-12 |
| EP1511484A1 (en) | 2005-03-09 |
| MXPA04011785A (es) | 2005-03-31 |
| JP2005532330A (ja) | 2005-10-27 |
| US20060074058A1 (en) | 2006-04-06 |
| RU2336876C2 (ru) | 2008-10-27 |
| IL165101A0 (en) | 2005-12-18 |
| WO2003099279A1 (en) | 2003-12-04 |
| NZ548971A (en) | 2008-04-30 |
| RU2004139025A (ru) | 2005-09-10 |
| PL372571A1 (en) | 2005-07-25 |
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