CA2486399C - Calcium receptor modulating agents - Google Patents

Calcium receptor modulating agents Download PDF

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Publication number
CA2486399C
CA2486399C CA2486399A CA2486399A CA2486399C CA 2486399 C CA2486399 C CA 2486399C CA 2486399 A CA2486399 A CA 2486399A CA 2486399 A CA2486399 A CA 2486399A CA 2486399 C CA2486399 C CA 2486399C
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Prior art keywords
methyl
methyloxy
phenyl
ethanamine
6alkyl
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CA2486399A
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English (en)
French (fr)
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CA2486399A1 (en
Inventor
Michael G. Kelly
Shimin Xu
Ning Xi
Philip Miller
John F. Kincaid
Chiara Ghiron
Thomas S. Coulter
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Amgen Inc
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Amgen Inc
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    • C07C233/00—Carboxylic acid amides
    • C07C233/01—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
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    • C07C233/35—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
    • C07C233/36—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of an acyclic saturated carbon skeleton
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    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
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    • A61P3/12—Drugs for disorders of the metabolism for electrolyte homeostasis
    • A61P3/14—Drugs for disorders of the metabolism for electrolyte homeostasis for calcium homeostasis
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    • C07C233/42—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring
    • C07C233/43—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by amino groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by a carbon atom of a six-membered aromatic ring having the carbon atom of the carboxamide group bound to a hydrogen atom or to a carbon atom of a saturated carbon skeleton
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    • C07C233/46—Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a hydrocarbon radical substituted by carboxyl groups with the substituted hydrocarbon radical bound to the nitrogen atom of the carboxamide group by an acyclic carbon atom
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AU2003233671A1 (en) 2003-12-12
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WO2003099776A1 (en) 2003-12-04
CA2486399A1 (en) 2003-12-04
US6908935B2 (en) 2005-06-21
AU2003233671B8 (en) 2003-12-12
US20050143426A1 (en) 2005-06-30
US7524873B2 (en) 2009-04-28
MXPA04011471A (es) 2005-02-14
JP2010150268A (ja) 2010-07-08
JP4486882B2 (ja) 2010-06-23
US20070142381A1 (en) 2007-06-21
EP1509497A1 (en) 2005-03-02
PL376438A1 (en) 2005-12-27
US20040082625A1 (en) 2004-04-29

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