CA2474801C - Human monoclonal antibody fab fragments directed against hcv e2 glycoprotein and endowed with in vitro neutralizing activity - Google Patents
Human monoclonal antibody fab fragments directed against hcv e2 glycoprotein and endowed with in vitro neutralizing activity Download PDFInfo
- Publication number
- CA2474801C CA2474801C CA2474801A CA2474801A CA2474801C CA 2474801 C CA2474801 C CA 2474801C CA 2474801 A CA2474801 A CA 2474801A CA 2474801 A CA2474801 A CA 2474801A CA 2474801 C CA2474801 C CA 2474801C
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- Prior art keywords
- hcv
- ser
- thr
- antibody
- gly
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Landscapes
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| ITRM2002A000049 | 2002-01-30 | ||
| PCT/IT2003/000032 WO2003064473A2 (en) | 2002-01-30 | 2003-01-29 | Human monoclonal antibody fab fragments directed against hcv e2 glycoprotein and endowed with in vitro neutralizing activity |
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| CA2474801A1 CA2474801A1 (en) | 2003-08-07 |
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| US7727962B2 (en) | 2004-05-10 | 2010-06-01 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Powder comprising new compositions of oligosaccharides and methods for their preparation |
| US7611709B2 (en) * | 2004-05-10 | 2009-11-03 | Boehringer Ingelheim Pharma Gmbh And Co. Kg | 1,4 O-linked saccharose derivatives for stabilization of antibodies or antibody derivatives |
| ITTO20070066A1 (it) | 2007-01-30 | 2008-07-31 | Pomona Biotechnologies Llc | Anticorpi monoclonali anti-idiotipo mimotopi dell'antigene gp 120 di hiv |
| WO2008107187A1 (en) * | 2007-03-06 | 2008-09-12 | Ribovax Biotechnologies S.A. | Antibodies specific for rubella virus |
| CN101809033A (zh) | 2007-07-25 | 2010-08-18 | 日本国立感染症研究所 | 对丙型肝炎病毒(hcv)感染具有抑制活性的抗体和其用途 |
| AU2008341542B2 (en) * | 2007-12-17 | 2014-12-04 | Medical Research Council Technology | Hepatitis C virus antibodies |
| ITTO20080204A1 (it) | 2008-03-17 | 2009-09-18 | Pomona Biotechnologies Llc | Anticorpi monoclonali atti a reagire con una pluralita di sottotipi del virus influenzale a |
| ITTO20080398A1 (it) | 2008-05-27 | 2009-11-28 | Pomona Biotechnologies Llc | Anticorpi monoclonali aventi proprieta' di cross-neutralizzazione omosubtipica per virus influenzali di tipo a sottotipo h1 |
| WO2010035292A1 (en) * | 2008-09-24 | 2010-04-01 | Natimab Therapeutics S.R.L. | The use of a human monoclonal anti-hcv antibody as a medicament for the therapeutic treatment and prevention of hcv infections |
| US20100104555A1 (en) * | 2008-10-24 | 2010-04-29 | The Scripps Research Institute | HCV neutralizing epitopes |
| ITTO20080964A1 (it) * | 2008-12-22 | 2010-06-23 | Natimab Therapeutics S R L | Anticorpo monoclonale anti-hcv come medicamento per il trattamento terapeutico e la prevenzione di infezioni da hcv |
| IT1395961B1 (it) | 2009-06-01 | 2012-11-02 | Pomona Biotechnologies Llc | Anticorpi monoclonali come medicamento per il trattamento terapeutico e/o profilattico delle infezioni da virus influenzale a (h1n1) di origine suina (s-oiv) |
| CN102596996B (zh) | 2009-10-30 | 2014-06-18 | 东丽株式会社 | 对丙型肝炎病毒(hcv)具有感染抑制活性的抗体及其用途 |
| JP6095984B2 (ja) | 2010-03-01 | 2017-03-15 | アニョロ, ヴィンセントAGNELLO, Vincent | Ｈｃｖ感染患者のクリオグロブリン血症性血管炎およびｂ細胞悪性腫瘍のための予後マーカー |
| CN104119436B (zh) * | 2013-04-27 | 2016-12-28 | 中国科学院上海生命科学研究院 | 抗丙型肝炎病毒的中和性全人单克隆抗体 |
| GB201415714D0 (en) * | 2014-09-05 | 2014-10-22 | Medical Res Council | Antibodies and antigen binding fragments thereof |
| CN105254756B (zh) * | 2015-11-27 | 2018-09-07 | 武汉大学 | 一种针对丙型肝炎病毒包膜蛋白e2的单克隆抗体及应用 |
| KR20180001380U (ko) | 2016-10-31 | 2018-05-10 | 대우조선해양 주식회사 | 해양구조물의 발로 작동시키는 캡스탄 |
| CN118440204A (zh) | 2019-12-27 | 2024-08-06 | 凯奥目生物科学株式会社 | 抗cdcp1抗体 |
| US20230312744A1 (en) | 2020-09-02 | 2023-10-05 | The University Of Tokyo | Modulatory Substance of Tumor Immune Microenvironment, and Preventive, Diagnostic and/or Therapeutic Utilization of the Same |
| US20250375498A1 (en) | 2022-07-28 | 2025-12-11 | The University Of Tokyo | Neurotrimin function inhibitor |
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| US6951646B1 (en) * | 1998-07-21 | 2005-10-04 | Genmab A/S | Anti hepatitis C virus antibody and uses thereof |
| US7091324B2 (en) * | 1998-11-05 | 2006-08-15 | Board Of Trustees Of Leland Stanford Junior University | Prevention and treatment of HCV infection employing antibodies directed against conformational epitopes |
| AU2001273363A1 (en) | 2000-07-12 | 2002-01-21 | General Instrument Corporation | Method and apparatus for downloading objects via an inband channel with minimal subscriber impact |
| JP2004524829A (ja) * | 2000-12-01 | 2004-08-19 | アメリカ合衆国 | Ｃ型肝炎ウイルスのｅ２糖タンパク質に特異的なモノクローナル抗体、ならびにｃ型肝炎の診断、治療、および予防におけるそれらの使用 |
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- 2002-01-30 IT IT2002RM000049A patent/ITRM20020049A1/it unknown
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2003
- 2003-01-29 NZ NZ534922A patent/NZ534922A/en not_active IP Right Cessation
- 2003-01-29 AU AU2003208000A patent/AU2003208000B2/en not_active Ceased
- 2003-01-29 DK DK03705004T patent/DK1476468T3/da active
- 2003-01-29 EP EP03705004A patent/EP1476468B9/en not_active Expired - Lifetime
- 2003-01-29 WO PCT/IT2003/000032 patent/WO2003064473A2/en not_active Ceased
- 2003-01-29 KR KR1020047011208A patent/KR101002791B1/ko not_active Expired - Fee Related
- 2003-01-29 CA CA2474801A patent/CA2474801C/en not_active Expired - Lifetime
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- 2003-01-29 JP JP2003564093A patent/JP4287280B2/ja not_active Expired - Fee Related
- 2003-01-29 ES ES03705004T patent/ES2314179T3/es not_active Expired - Lifetime
- 2003-01-29 US US10/502,307 patent/US20050084845A1/en not_active Abandoned
- 2003-01-29 CN CNA038030926A patent/CN1856508A/zh active Pending
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- 2003-01-29 EA EA200401081A patent/EA009861B1/ru not_active IP Right Cessation
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| KR20040077745A (ko) | 2004-09-06 |
| EP1476468B1 (en) | 2008-09-03 |
| WO2003064473A2 (en) | 2003-08-07 |
| EA200401081A1 (ru) | 2005-10-27 |
| US7727529B2 (en) | 2010-06-01 |
| JP4287280B2 (ja) | 2009-07-01 |
| JP2005531286A (ja) | 2005-10-20 |
| ITRM20020049A1 (it) | 2003-07-30 |
| CA2474801A1 (en) | 2003-08-07 |
| NZ534922A (en) | 2008-07-31 |
| EA009861B1 (ru) | 2008-04-28 |
| ES2314179T3 (es) | 2009-03-16 |
| WO2003064473A3 (en) | 2003-12-24 |
| US20080241162A1 (en) | 2008-10-02 |
| US20050084845A1 (en) | 2005-04-21 |
| ZA200406187B (en) | 2006-06-28 |
| DE60323333D1 (de) | 2008-10-16 |
| EP1476468B9 (en) | 2009-04-08 |
| ATE407147T1 (de) | 2008-09-15 |
| AU2003208000B2 (en) | 2010-05-20 |
| CN1856508A (zh) | 2006-11-01 |
| EP1476468A2 (en) | 2004-11-17 |
| RU2004126238A (ru) | 2005-04-20 |
| KR101002791B1 (ko) | 2010-12-21 |
| ITRM20020049A0 (it) | 2002-01-30 |
| DK1476468T3 (da) | 2009-01-19 |
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