CA2468967A1 - N-aryl-n'-arylcycloalkyl-urea derivatives as mch antagonists for the treatment of obesity - Google Patents

N-aryl-n'-arylcycloalkyl-urea derivatives as mch antagonists for the treatment of obesity Download PDF

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Publication number
CA2468967A1
CA2468967A1 CA002468967A CA2468967A CA2468967A1 CA 2468967 A1 CA2468967 A1 CA 2468967A1 CA 002468967 A CA002468967 A CA 002468967A CA 2468967 A CA2468967 A CA 2468967A CA 2468967 A1 CA2468967 A1 CA 2468967A1
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Prior art keywords
alkyl
compound
group
aryl
cycloalkyl
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English (en)
French (fr)
Inventor
John W. Clader
Anandan Palani
Ruo Xu
Mark D. Mc Briar
Jing Su
Haiqun Tang
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Merck Sharp and Dohme LLC
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    • C—CHEMISTRY; METALLURGY
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    • C07C2602/00—Systems containing two condensed rings
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    • C07C2602/14—All rings being cycloaliphatic
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00—Systems containing two condensed rings
    • C07C2602/02—Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/14—All rings being cycloaliphatic
    • C07C2602/20—All rings being cycloaliphatic the ring system containing seven carbon atoms

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US8394765B2 (en) 2004-11-01 2013-03-12 Amylin Pharmaceuticals Llc Methods of treating obesity with two different anti-obesity agents
AU2005305036B2 (en) * 2004-11-01 2011-03-10 Amylin Pharmaceuticals, Llc Treatment of obesity and related disorders
US20090264650A1 (en) * 2005-03-31 2009-10-22 Nobuo Cho Prophylactic/Therapeutic Agent for Diabetes
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RU2008107336A (ru) 2005-07-27 2009-09-10 Дов Фармасьютикал, Инк. (Us) Новые 1-арил-з-азабицикло{3.1.0.} гексаны: получение и применение для лечения психоневрологических расстройств
US20080045725A1 (en) 2006-04-28 2008-02-21 Murry Jerry A Process For The Synthesis of (+) And (-)-1-(3,4-Dichlorophenyl)-3-Azabicyclo[3.1.0]Hexane
US20080269348A1 (en) * 2006-11-07 2008-10-30 Phil Skolnick Novel Arylbicyclo[3.1.0]Hexylamines And Methods And Compositions For Their Preparation And Use
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US7348328B2 (en) 2008-03-25
WO2003047568A1 (en) 2003-06-12
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ATE404190T1 (de) 2008-08-15
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