ATE404190T1 - N-aryl-n'-arylcycloalkyl-harnstoff als mch antagonisten zur behandlung von fettleibigkeit - Google Patents

N-aryl-n'-arylcycloalkyl-harnstoff als mch antagonisten zur behandlung von fettleibigkeit

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Publication number
ATE404190T1
ATE404190T1 AT02782401T AT02782401T ATE404190T1 AT E404190 T1 ATE404190 T1 AT E404190T1 AT 02782401 T AT02782401 T AT 02782401T AT 02782401 T AT02782401 T AT 02782401T AT E404190 T1 ATE404190 T1 AT E404190T1
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Austria
Prior art keywords
arylcycloalkyl
urea
aryl
treating obesity
mch antagonist
Prior art date
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AT02782401T
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English (en)
Inventor
John Clader
Anandan Palani
Ruo Xu
Briar Mark Mc
Jing Su
Haiqun Tang
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Schering Corp
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Publication of ATE404190T1 publication Critical patent/ATE404190T1/de

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AT02782401T 2001-12-04 2002-12-03 N-aryl-n'-arylcycloalkyl-harnstoff als mch antagonisten zur behandlung von fettleibigkeit ATE404190T1 (de)

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US7030113B2 (en) * 2003-10-02 2006-04-18 Schering Corporation Aminobenzimidazoles as selective melanin concentrating hormone receptor antagonists for the treatment of obesity and related disorders
DE102004003811A1 (de) * 2004-01-25 2005-08-11 Aventis Pharma Deutschland Gmbh Substituierte N-Cyclohexylimidazolinone, Verfahren ihrer Herstellung und ihre Verwendung als Arzneimittel
EP1734963A4 (de) 2004-04-02 2008-06-18 Merck & Co Inc Verfahren zur behandlung von menschen mit metabolischen und anthropometrischen störungen
US7361769B2 (en) * 2004-07-16 2008-04-22 Schering Corporation Heterocyclyls as selective melanin concentrating hormone receptor antagonists for the treatment of obesity and related disorders
US20070043100A1 (en) 2005-08-16 2007-02-22 Hagen Eric J Novel polymorphs of azabicyclohexane
CA2583454A1 (en) * 2004-10-12 2006-04-27 Pharmacopeia Drug Discovery, Inc. Bicyclic compounds as selective melanin concentrating hormone receptor antagonists for the treatment of obesity and related disorders
DK1814590T4 (da) * 2004-11-01 2014-02-24 Amylin Pharmaceuticals Llc Behandling af obesitet og beslægtede sygdomme.
AU2005305036B2 (en) * 2004-11-01 2011-03-10 Amylin Pharmaceuticals, Llc Treatment of obesity and related disorders
US8394765B2 (en) 2004-11-01 2013-03-12 Amylin Pharmaceuticals Llc Methods of treating obesity with two different anti-obesity agents
JPWO2006104280A1 (ja) * 2005-03-31 2008-09-11 武田薬品工業株式会社 糖尿病の予防・治療剤
US7799943B2 (en) * 2005-06-24 2010-09-21 Rohm And Haas Company Method for promoting Michael addition reactions
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US20080045725A1 (en) 2006-04-28 2008-02-21 Murry Jerry A Process For The Synthesis of (+) And (-)-1-(3,4-Dichlorophenyl)-3-Azabicyclo[3.1.0]Hexane
US8138377B2 (en) * 2006-11-07 2012-03-20 Dov Pharmaceutical, Inc. Arylbicyclo[3.1.0]hexylamines and methods and compositions for their preparation and use
US20080269348A1 (en) * 2006-11-07 2008-10-30 Phil Skolnick Novel Arylbicyclo[3.1.0]Hexylamines And Methods And Compositions For Their Preparation And Use
CA2687230A1 (en) * 2007-05-23 2008-12-11 Merck & Co., Inc. Cyclopropyl pyrrolidine orexin receptor antagonists
US9133159B2 (en) 2007-06-06 2015-09-15 Neurovance, Inc. 1-heteroaryl-3-azabicyclo[3.1.0]hexanes, methods for their preparation and their use as medicaments
EP2036578A1 (de) * 2007-09-13 2009-03-18 Bayer Schering Pharma Aktiengesellschaft Diagnostische Wirkstoffe für die Positronenemissionstomographie mit radioaktiv markierten F18-Aminoalkoholen
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CN102875385A (zh) * 2012-10-18 2013-01-16 浙江大学 N,n-二异丙基乙胺的合成方法
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