CA2453734A1 - A thermoformed container for the culturing of cells - Google Patents
A thermoformed container for the culturing of cells Download PDFInfo
- Publication number
- CA2453734A1 CA2453734A1 CA002453734A CA2453734A CA2453734A1 CA 2453734 A1 CA2453734 A1 CA 2453734A1 CA 002453734 A CA002453734 A CA 002453734A CA 2453734 A CA2453734 A CA 2453734A CA 2453734 A1 CA2453734 A1 CA 2453734A1
- Authority
- CA
- Canada
- Prior art keywords
- container
- cells
- sheet
- sheets
- thermoformed
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
- 238000012258 culturing Methods 0.000 title claims abstract description 26
- 239000002861 polymer material Substances 0.000 claims abstract description 7
- 238000011084 recovery Methods 0.000 claims abstract description 5
- 239000000725 suspension Substances 0.000 claims abstract description 5
- 230000002093 peripheral effect Effects 0.000 claims description 11
- 238000003466 welding Methods 0.000 claims description 5
- 239000012530 fluid Substances 0.000 claims description 3
- 230000001788 irregular Effects 0.000 claims description 3
- 210000004027 cell Anatomy 0.000 description 62
- 238000004519 manufacturing process Methods 0.000 description 13
- 238000003856 thermoforming Methods 0.000 description 13
- 239000007789 gas Substances 0.000 description 11
- 239000002609 medium Substances 0.000 description 9
- 238000000034 method Methods 0.000 description 8
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 7
- 239000001301 oxygen Substances 0.000 description 7
- 229910052760 oxygen Inorganic materials 0.000 description 7
- 238000004113 cell culture Methods 0.000 description 6
- 230000035699 permeability Effects 0.000 description 6
- 239000001963 growth medium Substances 0.000 description 4
- 239000000463 material Substances 0.000 description 4
- 238000009826 distribution Methods 0.000 description 3
- 210000004524 haematopoietic cell Anatomy 0.000 description 3
- 238000004806 packaging method and process Methods 0.000 description 3
- 239000004793 Polystyrene Substances 0.000 description 2
- 239000000853 adhesive Substances 0.000 description 2
- 238000004026 adhesive bonding Methods 0.000 description 2
- 230000001070 adhesive effect Effects 0.000 description 2
- 239000002998 adhesive polymer Substances 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 210000001185 bone marrow Anatomy 0.000 description 2
- 239000003153 chemical reaction reagent Substances 0.000 description 2
- 238000011161 development Methods 0.000 description 2
- 230000018109 developmental process Effects 0.000 description 2
- 238000003780 insertion Methods 0.000 description 2
- 230000037431 insertion Effects 0.000 description 2
- 230000010412 perfusion Effects 0.000 description 2
- 229920000728 polyester Polymers 0.000 description 2
- -1 polyethylene Polymers 0.000 description 2
- 229920006254 polymer film Polymers 0.000 description 2
- 229920002223 polystyrene Polymers 0.000 description 2
- 230000002787 reinforcement Effects 0.000 description 2
- 230000004044 response Effects 0.000 description 2
- 238000004062 sedimentation Methods 0.000 description 2
- 238000004381 surface treatment Methods 0.000 description 2
- 238000012546 transfer Methods 0.000 description 2
- 229920008790 Amorphous Polyethylene terephthalate Polymers 0.000 description 1
- 241000206602 Eukaryota Species 0.000 description 1
- 241000282412 Homo Species 0.000 description 1
- 240000007817 Olea europaea Species 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 239000004743 Polypropylene Substances 0.000 description 1
- 230000003213 activating effect Effects 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 229920000249 biocompatible polymer Polymers 0.000 description 1
- 230000021164 cell adhesion Effects 0.000 description 1
- 230000011712 cell development Effects 0.000 description 1
- 230000004663 cell proliferation Effects 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000005038 ethylene vinyl acetate Substances 0.000 description 1
- 210000004700 fetal blood Anatomy 0.000 description 1
- 239000010408 film Substances 0.000 description 1
- 239000004811 fluoropolymer Substances 0.000 description 1
- 229920002313 fluoropolymer Polymers 0.000 description 1
- 238000001415 gene therapy Methods 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 210000003494 hepatocyte Anatomy 0.000 description 1
- 210000005260 human cell Anatomy 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 230000010354 integration Effects 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 230000003387 muscular Effects 0.000 description 1
- 210000003061 neural cell Anatomy 0.000 description 1
- 238000000399 optical microscopy Methods 0.000 description 1
- 238000006213 oxygenation reaction Methods 0.000 description 1
- 210000005259 peripheral blood Anatomy 0.000 description 1
- 239000011886 peripheral blood Substances 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 229920003023 plastic Polymers 0.000 description 1
- 239000004417 polycarbonate Substances 0.000 description 1
- 229920000515 polycarbonate Polymers 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 229920001155 polypropylene Polymers 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 210000001236 prokaryotic cell Anatomy 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 210000002536 stromal cell Anatomy 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 239000010409 thin film Substances 0.000 description 1
- 230000001131 transforming effect Effects 0.000 description 1
- 238000011282 treatment Methods 0.000 description 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29C—SHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
- B29C51/00—Shaping by thermoforming, i.e. shaping sheets or sheet like preforms after heating, e.g. shaping sheets in matched moulds or by deep-drawing; Apparatus therefor
- B29C51/14—Shaping by thermoforming, i.e. shaping sheets or sheet like preforms after heating, e.g. shaping sheets in matched moulds or by deep-drawing; Apparatus therefor using multilayered preforms or sheets
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/02—Form or structure of the vessel
- C12M23/10—Petri dish
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/20—Material Coatings
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/24—Gas permeable parts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
- C12M25/06—Plates; Walls; Drawers; Multilayer plates
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/505—Containers for the purpose of retaining a material to be analysed, e.g. test tubes flexible containers not provided for above
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
- B29K2025/00—Use of polymers of vinyl-aromatic compounds or derivatives thereof as moulding material
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
- B29K2067/00—Use of polyesters or derivatives thereof, as moulding material
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
- B29K2069/00—Use of PC, i.e. polycarbonates or derivatives thereof, as moulding material
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29K—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
- B29K2995/00—Properties of moulding materials, reinforcements, fillers, preformed parts or moulds
- B29K2995/0037—Other properties
- B29K2995/0065—Permeability to gases
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B29—WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
- B29L—INDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
- B29L2031/00—Other particular articles
- B29L2031/712—Containers; Packaging elements or accessories, Packages
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- Sustainable Development (AREA)
- Clinical Laboratory Science (AREA)
- Immunology (AREA)
- Mechanical Engineering (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Packages (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0216439A FR2849054B1 (fr) | 2002-12-20 | 2002-12-20 | Recipient thermoforme pour la culture de cellules |
| FR0216439 | 2002-12-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2453734A1 true CA2453734A1 (en) | 2004-06-20 |
Family
ID=32339005
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002453734A Abandoned CA2453734A1 (en) | 2002-12-20 | 2003-12-19 | A thermoformed container for the culturing of cells |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US20040132177A1 (enExample) |
| EP (1) | EP1431030B1 (enExample) |
| JP (1) | JP4584571B2 (enExample) |
| AT (1) | ATE332806T1 (enExample) |
| AU (1) | AU2003270995B2 (enExample) |
| CA (1) | CA2453734A1 (enExample) |
| DE (1) | DE60306736T2 (enExample) |
| ES (1) | ES2268300T3 (enExample) |
| FR (1) | FR2849054B1 (enExample) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5453629B2 (ja) * | 2006-08-23 | 2014-03-26 | タカラバイオ株式会社 | 遠心用袋状容器を使用した遺伝子導入方法 |
| DE102007007718A1 (de) * | 2007-02-16 | 2008-08-21 | Forschungszentrum Karlsruhe Gmbh | Bioreaktor, Anordnung aus Bioreaktoren, Verfahren zu ihrer Herstellung und ihre Verwendung |
| JP6594318B2 (ja) * | 2014-08-20 | 2019-10-23 | 国立大学法人広島大学 | ガス貯留マスク |
| JP2017184716A (ja) * | 2016-03-31 | 2017-10-12 | 東洋製罐グループホールディングス株式会社 | 細胞培養容器、細胞培養容器の支持治具、及び細胞培養方法 |
| EP3495467A4 (en) * | 2016-08-03 | 2020-07-29 | Toyo Seikan Group Holdings, Ltd. | METHOD AND DEVICE FOR PRODUCING A CONTAINER, CELL CULTURE VESSEL, METHOD FOR CULTIVATING CELLS, METHOD FOR PRODUCING A CELL CULTURE VESSEL AND DEVICE FOR PRODUCING A CELL CULTURE VESSEL |
| JP7057878B2 (ja) * | 2019-10-25 | 2022-04-21 | 東洋製罐グループホールディングス株式会社 | 接着細胞培養用器材、培養容器、細胞の剥離方法、及び接着細胞培養用器材の製造方法 |
| JP2021103973A (ja) * | 2019-12-26 | 2021-07-26 | 東洋製罐グループホールディングス株式会社 | 接着性細胞用培養容器、及び接着性細胞用培養容器の製造方法 |
| EP4180512A4 (en) * | 2020-07-11 | 2024-10-23 | Toyo Seikan Group Holdings, Ltd. | Cell culturing container, method for manufacturing cell culturing container, cell production method, cell culturing device, and cell culturing jig |
| JP2022027483A (ja) * | 2020-07-31 | 2022-02-10 | 東洋製罐グループホールディングス株式会社 | 細胞培養容器、細胞の製造方法、及び細胞培養容器の製造方法 |
| US12379916B2 (en) | 2022-03-10 | 2025-08-05 | Terumo Bct, Inc. | Communications and operation control of apheresis systems |
| US12458740B2 (en) | 2022-03-10 | 2025-11-04 | Terumo Bct, Inc. | Modular serviceability sleds and interconnections |
| US12478551B2 (en) | 2022-03-10 | 2025-11-25 | Terumo Bct, Inc. | Collection bottle with integrated cap, handle, and shield features |
Family Cites Families (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB8905001D0 (en) * | 1989-03-04 | 1989-04-19 | Univ Leicester | Screening for natural products of microbial metabolism |
| US5267344A (en) * | 1989-12-20 | 1993-11-30 | Dax Industries, Inc. | Direct current power control circuit for use in conjunction with regulated input signal |
| US5272084A (en) * | 1991-12-18 | 1993-12-21 | Corning Incorporated | Cell culture vessels having interior ridges and method for cultivating cells in same |
| JPH06335381A (ja) * | 1993-05-28 | 1994-12-06 | Dainippon Printing Co Ltd | 細胞培養基板 |
| EP0698085A4 (en) * | 1994-03-11 | 1996-08-21 | Baxter Int | CONTINUOUS FLOW BIOREACTOR WITH CELL RETENTION GROOVES |
| US5512480A (en) * | 1994-03-11 | 1996-04-30 | Baxter International Inc. | Flow-through bioreactor with grooves for cell retention |
| US6297046B1 (en) * | 1994-10-28 | 2001-10-02 | Baxter International Inc. | Multilayer gas-permeable container for the culture of adherent and non-adherent cells |
| FR2741357B1 (fr) * | 1995-11-22 | 1998-01-16 | Corning Inc | Procede de fabrication d'une plaquette de support d'un reseau bidimensionnel de micropuits, notamment pour essais ou cultures biologiques |
| US5795775A (en) * | 1996-09-26 | 1998-08-18 | Becton Dickinson And Company | Culture vessel and assembly |
| JP4112082B2 (ja) * | 1997-07-09 | 2008-07-02 | 昭和シェル石油株式会社 | Ｂｕｒｋｈｏｌｄｅｒｉａ ｃｅｐａｃｉａ １Ａの生育促進法および該微生物を用いたバイオリアクター |
| JP3761676B2 (ja) * | 1997-07-11 | 2006-03-29 | 株式会社メニコン | 細胞培養用容器 |
| AU6021699A (en) * | 1998-09-01 | 2000-03-21 | Penn State Research Foundation | Method and apparatus for aseptic growth or processing of biomass |
| US6306645B1 (en) * | 1999-06-25 | 2001-10-23 | Incell Ltd. | Container for explant culture, method of using same, and process, mold and apparatus of making same |
| JP2001218575A (ja) * | 2000-02-10 | 2001-08-14 | Sumitomo Bakelite Co Ltd | 培養用容器 |
| JP2002192180A (ja) * | 2000-12-27 | 2002-07-10 | Asupu:Kk | 浄化材 |
| US20040029266A1 (en) * | 2002-08-09 | 2004-02-12 | Emilio Barbera-Guillem | Cell and tissue culture device |
-
2002
- 2002-12-20 FR FR0216439A patent/FR2849054B1/fr not_active Expired - Fee Related
-
2003
- 2003-12-08 EP EP03293061A patent/EP1431030B1/fr not_active Expired - Lifetime
- 2003-12-08 DE DE60306736T patent/DE60306736T2/de not_active Expired - Lifetime
- 2003-12-08 AT AT03293061T patent/ATE332806T1/de not_active IP Right Cessation
- 2003-12-08 ES ES03293061T patent/ES2268300T3/es not_active Expired - Lifetime
- 2003-12-18 AU AU2003270995A patent/AU2003270995B2/en not_active Ceased
- 2003-12-19 US US10/742,658 patent/US20040132177A1/en not_active Abandoned
- 2003-12-19 CA CA002453734A patent/CA2453734A1/en not_active Abandoned
- 2003-12-22 JP JP2003425030A patent/JP4584571B2/ja not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| FR2849054A1 (fr) | 2004-06-25 |
| EP1431030A1 (fr) | 2004-06-23 |
| JP2004201689A (ja) | 2004-07-22 |
| AU2003270995A1 (en) | 2004-07-08 |
| EP1431030B1 (fr) | 2006-07-12 |
| JP4584571B2 (ja) | 2010-11-24 |
| ATE332806T1 (de) | 2006-08-15 |
| AU2003270995B2 (en) | 2011-09-22 |
| DE60306736D1 (de) | 2006-08-24 |
| ES2268300T3 (es) | 2007-03-16 |
| DE60306736T2 (de) | 2007-08-02 |
| US20040132177A1 (en) | 2004-07-08 |
| FR2849054B1 (fr) | 2005-06-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FZDE | Discontinued |