CA2451037A1 - Method of treating malignancy associated hypercalcemia using active vitamin d analogues - Google Patents
Method of treating malignancy associated hypercalcemia using active vitamin d analogues Download PDFInfo
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- CA2451037A1 CA2451037A1 CA002451037A CA2451037A CA2451037A1 CA 2451037 A1 CA2451037 A1 CA 2451037A1 CA 002451037 A CA002451037 A CA 002451037A CA 2451037 A CA2451037 A CA 2451037A CA 2451037 A1 CA2451037 A1 CA 2451037A1
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- Prior art keywords
- compound
- accordance
- vitamin
- hydrogen
- alpha
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- 238000010254 subcutaneous injection Methods 0.000 description 1
- 239000002511 suppository base Substances 0.000 description 1
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- 235000020357 syrup Nutrition 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 235000012222 talc Nutrition 0.000 description 1
- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
- 230000002381 testicular Effects 0.000 description 1
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- 150000003626 triacylglycerols Chemical class 0.000 description 1
- YNJBWRMUSHSURL-UHFFFAOYSA-N trichloroacetic acid Chemical compound OC(=O)C(Cl)(Cl)Cl YNJBWRMUSHSURL-UHFFFAOYSA-N 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/02—Nutrients, e.g. vitamins, minerals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nutrition Science (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/891,763 US6566353B2 (en) | 1996-12-30 | 2001-06-26 | Method of treating malignancy associated hypercalcemia using active vitamin D analogues |
| US09/891,763 | 2001-06-26 | ||
| PCT/US2002/020320 WO2003002060A2 (en) | 2001-06-26 | 2002-06-26 | Method of treating malignancy associated hypercalcemia using active vitamin d analogues |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA2451037A1 true CA2451037A1 (en) | 2003-01-09 |
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Family Applications (1)
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|---|---|---|---|
| CA002451037A Abandoned CA2451037A1 (en) | 2001-06-26 | 2002-06-26 | Method of treating malignancy associated hypercalcemia using active vitamin d analogues |
Country Status (9)
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|---|---|
| US (2) | US6566353B2 (enExample) |
| EP (1) | EP1416939A2 (enExample) |
| JP (1) | JP2004535439A (enExample) |
| KR (1) | KR20040015301A (enExample) |
| CN (1) | CN1520301A (enExample) |
| CA (1) | CA2451037A1 (enExample) |
| IL (1) | IL159069A0 (enExample) |
| MX (1) | MXPA03011305A (enExample) |
| WO (1) | WO2003002060A2 (enExample) |
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| US5763429A (en) * | 1993-09-10 | 1998-06-09 | Bone Care International, Inc. | Method of treating prostatic diseases using active vitamin D analogues |
| US6566353B2 (en) * | 1996-12-30 | 2003-05-20 | Bone Care International, Inc. | Method of treating malignancy associated hypercalcemia using active vitamin D analogues |
| US20020128240A1 (en) * | 1996-12-30 | 2002-09-12 | Bone Care International, Inc. | Treatment of hyperproliferative diseases using active vitamin D analogues |
| US6087350A (en) * | 1997-08-29 | 2000-07-11 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Use of pretreatment chemicals to enhance efficacy of cytotoxic agents |
| ES2368824T3 (es) * | 1998-03-27 | 2011-11-22 | Oregon Health & Science University | Vitamina d y sus análogos en el tratamiento de tumores y otros desórdenes hiperproliferativos. |
| HUP0501186A2 (en) * | 2001-12-03 | 2006-05-29 | Novacea | Pharmaceutical compositions comprising active vitamin d compounds |
| US20050026877A1 (en) * | 2002-12-03 | 2005-02-03 | Novacea, Inc. | Pharmaceutical compositions comprising active vitamin D compounds |
| US20050020546A1 (en) * | 2003-06-11 | 2005-01-27 | Novacea, Inc. | Pharmaceutical compositions comprising active vitamin D compounds |
| BRPI0414701A (pt) * | 2003-09-24 | 2006-11-14 | Bioxell Spa | uso de um composto de vitamina d, método de prevenção ou tratamnento de disfunção de bexiga em um paciente, composto de vitamina d, e, kit |
| WO2005097128A1 (en) * | 2004-03-30 | 2005-10-20 | Novacea, Inc. | 1,4-bis-n-oxide azaanthracenediones and the use thereof |
| WO2005101022A2 (en) * | 2004-04-15 | 2005-10-27 | Bayer Healthcare Ag | Diagnostics and therapeutics for diseases associated with vitamin d (1,25-dihydroxyvitamin d3) receptor 1 (vdr1) |
| US20060003950A1 (en) * | 2004-06-30 | 2006-01-05 | Bone Care International, Inc. | Method of treating prostatic diseases using a combination of vitamin D analogues and other agents |
| US8501717B2 (en) * | 2007-02-09 | 2013-08-06 | Merck, Sharp & Dohme Corp. | Methods to treat and/or prevent mucositis |
| RU2505315C2 (ru) * | 2008-07-30 | 2014-01-27 | Нитто Денко Корпорейшн | Носители лекарственных средств |
| MX2015014701A (es) | 2013-04-24 | 2016-08-08 | Salk Inst For Biological Studi | Circuito genomico del receptor de vitamina d/smad que regula la compuerta de la respuesta fibrotica. |
| CN105451818A (zh) * | 2013-06-05 | 2016-03-30 | 萨克生物研究学院 | 治疗涉及cxcl12活性的疾病的维生素d受体激动剂 |
| JP6428665B2 (ja) * | 2016-02-10 | 2018-11-28 | 三菱電機株式会社 | 空中映像表示装置 |
| WO2019023149A1 (en) | 2017-07-24 | 2019-01-31 | Salk Institute For Biological Studies | USE OF BROMODOMAIN-CONTAINING PROTEIN-9 ANTAGONISTS IN ASSOCIATION WITH VITAMIN D RECEPTOR AGONISTS IN THE TREATMENT OF DIABETES |
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| FR2798855B1 (fr) * | 1999-09-28 | 2003-04-25 | Oreal | Utilisation de complexes inorganiques-organiques dans une composition a usage topique |
| DK1220676T3 (da) | 1999-09-29 | 2005-09-05 | Colotech As | Forebyggelse af colorektal cancer |
| AU7995300A (en) * | 1999-10-05 | 2001-05-10 | Bethesda Pharmaceuticals, Inc. | Dithiolane derivatives |
| AU776395B2 (en) * | 1999-12-06 | 2004-09-09 | Leo Pharmaceutical Products Ltd. A/S (Lovens Kemiske Fabrik Produktionsaktieselskab) | Aminobenzophenones as inhibitors of IL-1beta and TNF-alpha |
| US6989377B2 (en) * | 1999-12-21 | 2006-01-24 | Wisconsin Alumni Research Foundation | Treating vitamin D responsive diseases |
| JP2003525254A (ja) | 2000-03-02 | 2003-08-26 | ユニヴァーシティ オヴ ピッツバーグ オヴ ザ コモンウェルス システム オヴ ハイアー エデュケーション | 併用化学療法 |
| CA2408727A1 (en) * | 2000-05-22 | 2001-11-29 | Leo Pharma A/S | Benzophenones as inhibitors of il-1.beta. and tnf-.alpha. |
| US6395784B1 (en) * | 2000-06-07 | 2002-05-28 | Bristol-Myers Squibb Company | Benzamide ligands for the thyroid receptor |
| JP3706104B2 (ja) * | 2000-06-15 | 2005-10-12 | 中外製薬株式会社 | ビタミンｄ誘導体 |
| US20030149005A1 (en) * | 2001-08-22 | 2003-08-07 | Posner Gary H. | 24-sulfur-substituted analogs of 1alpha, 25-dihydroxy vitamin D3 |
-
2001
- 2001-06-26 US US09/891,763 patent/US6566353B2/en not_active Expired - Fee Related
-
2002
- 2002-06-26 MX MXPA03011305A patent/MXPA03011305A/es unknown
- 2002-06-26 JP JP2003508302A patent/JP2004535439A/ja active Pending
- 2002-06-26 CA CA002451037A patent/CA2451037A1/en not_active Abandoned
- 2002-06-26 EP EP02747979A patent/EP1416939A2/en not_active Withdrawn
- 2002-06-26 IL IL15906902A patent/IL159069A0/xx unknown
- 2002-06-26 KR KR10-2003-7017015A patent/KR20040015301A/ko not_active Withdrawn
- 2002-06-26 CN CNA028128710A patent/CN1520301A/zh active Pending
- 2002-06-26 WO PCT/US2002/020320 patent/WO2003002060A2/en not_active Ceased
-
2003
- 2003-05-20 US US10/441,731 patent/US20030207810A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| US6566353B2 (en) | 2003-05-20 |
| US20020010165A1 (en) | 2002-01-24 |
| EP1416939A2 (en) | 2004-05-12 |
| MXPA03011305A (es) | 2004-03-19 |
| WO2003002060A2 (en) | 2003-01-09 |
| KR20040015301A (ko) | 2004-02-18 |
| US20030207810A1 (en) | 2003-11-06 |
| WO2003002060A3 (en) | 2004-03-11 |
| CN1520301A (zh) | 2004-08-11 |
| JP2004535439A (ja) | 2004-11-25 |
| IL159069A0 (en) | 2004-05-12 |
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| Date | Code | Title | Description |
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| FZDE | Discontinued |