CA2448120A1 - Muscle-specific expression vectors - Google Patents
Muscle-specific expression vectors Download PDFInfo
- Publication number
- CA2448120A1 CA2448120A1 CA002448120A CA2448120A CA2448120A1 CA 2448120 A1 CA2448120 A1 CA 2448120A1 CA 002448120 A CA002448120 A CA 002448120A CA 2448120 A CA2448120 A CA 2448120A CA 2448120 A1 CA2448120 A1 CA 2448120A1
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- Prior art keywords
- promoter
- enhancer
- muscle
- mck
- regulatory element
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
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- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
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| US20080044393A1 (en) * | 2004-07-16 | 2008-02-21 | White Robert L | Retinal dystrophin transgene and methods of use thereof |
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| US8383601B2 (en) * | 2006-10-30 | 2013-02-26 | Thomas Jefferson University | Tissue specific gene therapy treatment |
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| CA2834729A1 (en) | 2011-04-06 | 2012-10-11 | Universite Pierre Et Marie Curie (Paris 6) | A skeletal muscle-specific enhancer |
| SMT202000445T1 (it) * | 2012-06-19 | 2020-09-10 | Univ Florida | Composizioni e metodi per trattare patologie |
| WO2014028762A1 (en) | 2012-08-15 | 2014-02-20 | University Of Virginia Patent Foundation | Compositions and methods for treating peripheral arterial disease |
| JP2016502858A (ja) | 2012-12-20 | 2016-02-01 | サレプタ セラピューティクス， インコーポレイテッド | 筋ジストロフィを処置するための改善されたエキソンスキッピング組成物 |
| EA202090946A3 (ru) | 2013-03-14 | 2021-07-30 | Сарепта Терапьютикс, Инк. | Композиции, обеспечивающие пропускание экзонов, для лечения мышечной дистрофии |
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| WO2015035364A1 (en) * | 2013-09-09 | 2015-03-12 | University Of Washington Through Its Center For Commercialization | Proteins for targeting neuronal nitric oxide synthase to muscle sarcolemma and related methods of use |
| SG11201605906UA (en) | 2014-01-21 | 2016-08-30 | Univ Bruxelles | Muscle-specific nucleic acid regulatory elements and methods and use thereof |
| CA2980819C (en) | 2015-03-05 | 2024-03-05 | Peter Und Traudl Engelhorn-Stiftung Zur Forderung Der Lebenswissenschaften | System for the presentation of peptides on the cell surface |
| GB201508025D0 (en) | 2015-05-11 | 2015-06-24 | Ucl Business Plc | Fabry disease gene therapy |
| CN104894651B (zh) * | 2015-06-29 | 2017-04-12 | 天津诺禾医学检验所有限公司 | 微量起始dna的高通量测序文库构建方法及其所构建的高通量测序文库 |
| AU2016323575B2 (en) * | 2015-09-17 | 2022-10-27 | Research Institute At Nationwide Children's Hospital | Methods and materials for GALGT2 gene therapy |
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| US11202840B2 (en) | 2016-06-21 | 2021-12-21 | The Curators Of The University Of Missouri | Modified dystrophin proteins |
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| PT1071806E (pt) * | 1998-04-24 | 2004-09-30 | Univ Florida | Vector viral adeno-associado recombinante que codifica a alfa-1-antitripsina para terapia genetica |
| EP1287125B1 (en) * | 2000-04-28 | 2009-07-29 | Asklepios Biopharmaceutical, Inc. | Dna sequences encoding dystrophin minigenes and methods of use thereof |
| WO2001083703A2 (en) * | 2000-05-04 | 2001-11-08 | California Institute Of Technology | Checkpoint-activating oligonucleotides |
-
2002
- 2002-05-22 CA CA002448120A patent/CA2448120A1/en not_active Abandoned
- 2002-05-22 EP EP02739449A patent/EP1390490B1/en not_active Expired - Lifetime
- 2002-05-22 AT AT02739449T patent/ATE428777T1/de not_active IP Right Cessation
- 2002-05-22 WO PCT/US2002/016748 patent/WO2002095006A2/en not_active Ceased
- 2002-05-22 DE DE60231975T patent/DE60231975D1/de not_active Expired - Lifetime
- 2002-05-22 JP JP2002592469A patent/JP2004535801A/ja active Pending
- 2002-05-22 EP EP08103273A patent/EP2017338A1/en not_active Withdrawn
- 2002-05-24 US US10/156,604 patent/US20030100526A1/en not_active Abandoned
-
2007
- 2007-03-12 US US11/716,899 patent/US20110212529A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| JP2004535801A (ja) | 2004-12-02 |
| WO2002095006A2 (en) | 2002-11-28 |
| ATE428777T1 (de) | 2009-05-15 |
| EP1390490A4 (en) | 2005-05-11 |
| DE60231975D1 (de) | 2009-05-28 |
| EP1390490B1 (en) | 2009-04-15 |
| WO2002095006A3 (en) | 2003-03-13 |
| US20030100526A1 (en) | 2003-05-29 |
| EP2017338A1 (en) | 2009-01-21 |
| US20110212529A1 (en) | 2011-09-01 |
| EP1390490A2 (en) | 2004-02-25 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| FZDE | Discontinued |