CA2446622C - Isostearic acid salts as permeation enhancers - Google Patents
Isostearic acid salts as permeation enhancers Download PDFInfo
- Publication number
- CA2446622C CA2446622C CA2446622A CA2446622A CA2446622C CA 2446622 C CA2446622 C CA 2446622C CA 2446622 A CA2446622 A CA 2446622A CA 2446622 A CA2446622 A CA 2446622A CA 2446622 C CA2446622 C CA 2446622C
- Authority
- CA
- Canada
- Prior art keywords
- functional group
- group
- formula
- straight chain
- coona
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US29043701P | 2001-05-11 | 2001-05-11 | |
US60/290,437 | 2001-05-11 | ||
PCT/US2002/015211 WO2002092070A1 (en) | 2001-05-11 | 2002-05-13 | Isostearic acid salts as permeation enhancers |
Publications (2)
Publication Number | Publication Date |
---|---|
CA2446622A1 CA2446622A1 (en) | 2002-11-21 |
CA2446622C true CA2446622C (en) | 2012-08-14 |
Family
ID=23115994
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CA2446622A Expired - Fee Related CA2446622C (en) | 2001-05-11 | 2002-05-13 | Isostearic acid salts as permeation enhancers |
Country Status (5)
Country | Link |
---|---|
US (1) | US20030018085A1 (ja) |
EP (1) | EP1390024A4 (ja) |
JP (1) | JP2004529953A (ja) |
CA (1) | CA2446622C (ja) |
WO (1) | WO2002092070A1 (ja) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8119159B2 (en) | 1999-02-22 | 2012-02-21 | Merrion Research Iii Limited | Solid oral dosage form containing an enhancer |
US7658938B2 (en) | 1999-02-22 | 2010-02-09 | Merrion Reasearch III Limited | Solid oral dosage form containing an enhancer |
US6503894B1 (en) | 2000-08-30 | 2003-01-07 | Unimed Pharmaceuticals, Inc. | Pharmaceutical composition and method for treating hypogonadism |
US20040002482A1 (en) * | 2000-08-30 | 2004-01-01 | Dudley Robert E. | Androgen pharmaceutical composition and method for treating depression |
US20040092494A9 (en) * | 2000-08-30 | 2004-05-13 | Dudley Robert E. | Method of increasing testosterone and related steroid concentrations in women |
US20030176379A1 (en) * | 2001-05-11 | 2003-09-18 | Raoof Araz A. | Antisense permeation enhancers |
US8741333B2 (en) * | 2004-06-07 | 2014-06-03 | Nuvo Research Inc. | Compositions and methods for treating dermatitis or psoriasis |
US20070196452A1 (en) * | 2004-06-07 | 2007-08-23 | Jie Zhang | Flux-enabling compositions and methods for dermal delivery of drugs |
US8741332B2 (en) * | 2004-06-07 | 2014-06-03 | Nuvo Research Inc. | Compositions and methods for dermally treating neuropathic pain |
US20070196325A1 (en) * | 2004-06-07 | 2007-08-23 | Jie Zhang | Compositions and methods for dermally treating infections |
US8907153B2 (en) | 2004-06-07 | 2014-12-09 | Nuvo Research Inc. | Adhesive peel-forming formulations for dermal delivery of drugs and methods of using the same |
US20070088012A1 (en) * | 2005-04-08 | 2007-04-19 | Woun Seo | Method of treating or preventing type-2 diabetes |
NO346660B1 (no) | 2005-10-12 | 2022-11-21 | Unimed Pharmaceuticals Llc | Forbedret testosterongel og fremgangsmåte til anvendelse |
BRPI0710503A2 (pt) | 2006-04-07 | 2011-08-16 | Merrion Res Iii Ltd | uso de uma composição farmacêutica, composição farmacêutica, e, forma de dosagem oral |
US20070280972A1 (en) * | 2006-04-25 | 2007-12-06 | Zars, Inc. | Adhesive solid gel-forming formulations for dermal drug delivery |
MX2010012201A (es) | 2008-05-07 | 2011-05-30 | Merrion Res Iii Ltd | Composiciones de péptidos y procedimientos de preparación de las mismas. |
WO2011120033A1 (en) | 2010-03-26 | 2011-09-29 | Merrion Research Iii Limited | Pharmaceutical compositions of selective factor xa inhibitors for oral administration |
EP2661273A4 (en) | 2011-01-07 | 2014-06-04 | Merrion Res Iii Ltd | IRON PHARMACEUTICAL COMPOSITIONS FOR ORAL ADMINISTRATION |
EP3250191B1 (en) | 2015-01-29 | 2024-01-17 | Novo Nordisk A/S | Tablets comprising glp-1 agonist and enteric coating |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4525339A (en) * | 1982-10-15 | 1985-06-25 | Hoffmann-La Roche Inc. | Enteric coated oral dosage form |
DE3331009A1 (de) * | 1983-08-27 | 1985-03-14 | Basf Ag, 6700 Ludwigshafen | Verfahren zur erhoehung der enteralen resorbierbarkeit von heparin bzw. heparinoiden sowie das so erhaeltliche heparin- bzw. heparinoidpraeparat |
JPS61200904A (ja) * | 1985-03-04 | 1986-09-05 | Shiseido Co Ltd | 外用尿素製剤 |
US5190748A (en) * | 1988-11-22 | 1993-03-02 | Hoffmann-La Roche Inc. | Absorption enhancement of antibiotics |
IL92537A (en) * | 1988-12-15 | 1994-04-12 | Riker Laboratories Inc | Topical preparations and dermal systems containing 1-isobutyl-H1-imidazo [C-4,5] quinoline-4-amine |
JPH02207018A (ja) * | 1989-02-07 | 1990-08-16 | Kao Corp | 皮膚外用剤 |
WO1991019486A1 (en) * | 1990-06-14 | 1991-12-26 | Kalmo Enterprises, Inc. | Stable aqueous drug suspensions |
US5541155A (en) * | 1994-04-22 | 1996-07-30 | Emisphere Technologies, Inc. | Acids and acid salts and their use in delivery systems |
US5229130A (en) * | 1991-12-20 | 1993-07-20 | Cygnus Therapeutics Systems | Vegetable oil-based skin permeation enhancer compositions, and associated methods and systems |
JP3190441B2 (ja) * | 1992-07-20 | 2001-07-23 | エーザイ株式会社 | 塩酸アゼラスチンを含有する安定な製剤 |
SE9302135D0 (sv) * | 1993-06-18 | 1993-06-18 | Kabi Pharmacia Ab | New pharmaceutical composition |
US5650386A (en) * | 1995-03-31 | 1997-07-22 | Emisphere Technologies, Inc. | Compositions for oral delivery of active agents |
KR19990014865A (ko) * | 1995-05-17 | 1999-02-25 | 피터 이. 브래이브맨 | 소장에서의 소화 및 흡수를 증진시키기 위한, 지방산을 함유한조성물들 |
GB9516268D0 (en) * | 1995-08-08 | 1995-10-11 | Danbiosyst Uk | Compositiion for enhanced uptake of polar drugs from the colon |
JP4181232B2 (ja) * | 1997-07-18 | 2008-11-12 | 帝國製薬株式会社 | ジクロフェナクナトリウム含有油性外用貼付製剤 |
DE69910183T2 (de) * | 1998-03-11 | 2004-06-03 | Grelan Pharmaceutical Co., Ltd., Hamura | Darmlösliche sprudelnde zusammensetzungen |
WO1999047117A1 (en) * | 1998-03-16 | 1999-09-23 | The Procter & Gamble Company | Skin moisturizing compositions |
GB9814062D0 (en) * | 1998-06-29 | 1998-08-26 | Procter & Gamble | Hair shampoo and conditioner system |
SK287112B6 (sk) * | 1999-01-08 | 2009-12-07 | 3M Innovative Properties Company | Použitie zlúčeniny modifikujúcej imunitnú odpoveď pri liečení cervikálnej dysplázie |
US6309663B1 (en) * | 1999-08-17 | 2001-10-30 | Lipocine Inc. | Triglyceride-free compositions and methods for enhanced absorption of hydrophilic therapeutic agents |
US20030176379A1 (en) * | 2001-05-11 | 2003-09-18 | Raoof Araz A. | Antisense permeation enhancers |
-
2002
- 2002-05-13 WO PCT/US2002/015211 patent/WO2002092070A1/en active Application Filing
- 2002-05-13 US US10/145,180 patent/US20030018085A1/en not_active Abandoned
- 2002-05-13 JP JP2002588987A patent/JP2004529953A/ja active Pending
- 2002-05-13 CA CA2446622A patent/CA2446622C/en not_active Expired - Fee Related
- 2002-05-13 EP EP02731787A patent/EP1390024A4/en not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
CA2446622A1 (en) | 2002-11-21 |
EP1390024A1 (en) | 2004-02-25 |
WO2002092070A1 (en) | 2002-11-21 |
EP1390024A4 (en) | 2010-02-17 |
JP2004529953A (ja) | 2004-09-30 |
US20030018085A1 (en) | 2003-01-23 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CA2446622C (en) | Isostearic acid salts as permeation enhancers | |
US7820722B2 (en) | Permeation enhancers | |
ES2557475T3 (es) | Un portador que comprende uno o más derivados di- y/o monofosfato de agentes de transferencia de electrones | |
US9175027B2 (en) | Polymer-carbohydrate-lipid conjugates | |
JP2020189864A5 (ja) | ||
JP2020040958A (ja) | 炎症を低減させるための新規揮発性麻酔薬製剤およびその使用法 | |
EA010295B1 (ru) | Соединения амфетамина с пониженной способностью вызывать злоупотребление ими | |
JPH10504835A (ja) | 胆汁酸塩および活性化合物の生物学的利用能を向上させる緩衝液を含む薬剤組成物 | |
CN103189068A (zh) | 用于药物施用的组合物 | |
CN116367837A (zh) | 抗病毒化合物的制剂 | |
RU2542449C2 (ru) | Композиции и способы лечения рака мочевого пузыря | |
CN101831067A (zh) | 聚乙二醇脂类缀合物及其在制备药物中的应用 | |
CN112823787A (zh) | 一种含有美洛昔康的注射液及其制备方法 | |
JP2002524417A5 (ja) | ||
EP1515706A2 (en) | A platform for transdermal formulations (ptf) | |
CN109496152A (zh) | 癸氧喹酯组合物的肌肉内库存及其预防和治疗的方法 | |
JP6950958B2 (ja) | 核酸を含む経腸投与用組成物 | |
WO2024059753A2 (en) | Therapeutic regimens and methods for reducing body weight in a subject with fatty liver disease using a glp-1r and gcgr agonist | |
EP4208160A1 (en) | Ionic liquid formulations for treating diabetes | |
RU2541156C1 (ru) | Трансдермальное антигельминтное средство на основе кремнийорганических ниосом с альбендазолом | |
JP4879332B2 (ja) | 神経障害性疼痛抑制薬 | |
CN115916142A (zh) | 偶联萜烯缀合物 | |
Strauss | Peroral delivery of calcitonin with pheroid technology | |
EP1660522A2 (en) | Pharmaceutical composition with increased bioavailability suitable for the administration of oral retroviral protease inhibitors. process for preparing a concentrate pharmaceutical composition comprising a retroviral protease inhibitor | |
JPH03128327A (ja) | モチリン製剤 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
EEER | Examination request | ||
MKLA | Lapsed |
Effective date: 20170515 |