US20030176379A1 - Antisense permeation enhancers - Google Patents

Antisense permeation enhancers Download PDF

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Publication number
US20030176379A1
US20030176379A1 US10/145,181 US14518102A US2003176379A1 US 20030176379 A1 US20030176379 A1 US 20030176379A1 US 14518102 A US14518102 A US 14518102A US 2003176379 A1 US2003176379 A1 US 2003176379A1
Authority
US
United States
Prior art keywords
antisense
composition
sodium
enhancer
oligonucleotide
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
US10/145,181
Inventor
Araz Raoof
Mangaraju Gudipati
David Bibby
Susan Reingold
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ionis Pharmaceuticals Inc
Original Assignee
ORASENSE Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to US29043601P priority Critical
Application filed by ORASENSE Ltd filed Critical ORASENSE Ltd
Priority to US10/145,181 priority patent/US20030176379A1/en
Publication of US20030176379A1 publication Critical patent/US20030176379A1/en
Assigned to ORASENSE LTD. reassignment ORASENSE LTD. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: REINGOLD, SUSAN WEINBACH, RAOOF, ARAZ A., BIBBY, DAVID C., GUDIPATI, MANGARAJU
Assigned to ORASENSE, LTD. reassignment ORASENSE, LTD. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: PARSHALL, B. LYNNE
Assigned to ISIS PHARMACEUTICALS, INC. reassignment ISIS PHARMACEUTICALS, INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: ORASENSE, LTD.
Application status is Abandoned legal-status Critical

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