CA2405741C - Nouveau sel d'un derive azoique d'acide 5-aminosalicylique - Google Patents

Nouveau sel d'un derive azoique d'acide 5-aminosalicylique Download PDF

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Publication number
CA2405741C
CA2405741C CA2405741A CA2405741A CA2405741C CA 2405741 C CA2405741 C CA 2405741C CA 2405741 A CA2405741 A CA 2405741A CA 2405741 A CA2405741 A CA 2405741A CA 2405741 C CA2405741 C CA 2405741C
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CA
Canada
Prior art keywords
phenyl
methyl
sodium salt
azo
oxo
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
CA2405741A
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English (en)
Other versions
CA2405741A1 (fr
Inventor
Elena Carceller
Jorge Salas
Jose Ignacio Escamilla
Joaquim Ramis
Javier Forn
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Palau Pharma SA
Original Assignee
Palau Pharma SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Palau Pharma SA filed Critical Palau Pharma SA
Publication of CA2405741A1 publication Critical patent/CA2405741A1/fr
Application granted granted Critical
Publication of CA2405741C publication Critical patent/CA2405741C/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

L'invention concerne un sel de sodium de l'acide (Z)-2-hydroxy-5-[[4-[3-[4-[(2-méthyl-1H-imidazo[4,5-c]pyridin-1-yl)méthyl]-1-pipéridinyl]-3-oxo-1-phényl-1-propényl]phényl]azo]benzoïque ainsi que des compositions pharmaceutiques le contenant, une procédure de préparation et son utilisation dans la fabrication de médicaments pour le traitement ou la prévention de l'affection intestinale inflammatoire.
CA2405741A 2000-04-10 2001-04-10 Nouveau sel d'un derive azoique d'acide 5-aminosalicylique Expired - Fee Related CA2405741C (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ES200000996 2000-04-10
ES200000996A ES2165803B1 (es) 2000-04-10 2000-04-10 Nueva sal de un derivado azo del acido 5-aminosalicilico
PCT/EP2001/004109 WO2001077109A2 (fr) 2000-04-10 2001-04-10 Nouveau sel d'un derive azoique d'acide 5-aminosalicylique

Publications (2)

Publication Number Publication Date
CA2405741A1 CA2405741A1 (fr) 2001-10-18
CA2405741C true CA2405741C (fr) 2010-11-02

Family

ID=8493217

Family Applications (1)

Application Number Title Priority Date Filing Date
CA2405741A Expired - Fee Related CA2405741C (fr) 2000-04-10 2001-04-10 Nouveau sel d'un derive azoique d'acide 5-aminosalicylique

Country Status (18)

Country Link
US (1) US6809087B2 (fr)
EP (1) EP1272490B1 (fr)
JP (2) JP4597463B2 (fr)
KR (2) KR100859296B1 (fr)
AR (1) AR033363A1 (fr)
AT (1) ATE372999T1 (fr)
AU (1) AU2001273937A1 (fr)
BR (1) BR0109935A (fr)
CA (1) CA2405741C (fr)
CY (1) CY1107090T1 (fr)
DE (1) DE60130444T2 (fr)
DK (1) DK1272490T3 (fr)
ES (2) ES2165803B1 (fr)
HK (1) HK1052184B (fr)
MX (1) MXPA02009934A (fr)
NO (1) NO323955B1 (fr)
PT (1) PT1272490E (fr)
WO (1) WO2001077109A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8048924B2 (en) 2001-08-29 2011-11-01 Biocon Limited Methods and compositions employing 4-aminophenylacetic acid compounds
ES2565848T3 (es) 2004-07-07 2016-04-07 Biocon Limited Síntesis de compuestos inmunorreguladores unidos por grupos azoicos

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4312806A (en) * 1981-03-02 1982-01-26 G. D. Searle & Co. Method and compounds for treating inflammatory bowel disease
PT98673B (pt) * 1990-08-15 1999-01-29 British Bio Technology Processo para a preparacao de compostos que sao antagonistas do factor de activacao de plaquetas por exemplo derivados de benzimidazole e de seus intermediarios
ES2087038B1 (es) * 1994-11-07 1997-03-16 Uriach & Cia Sa J Nuevas piperidinas con actividad antagonista del paf.
US5747477A (en) * 1995-09-08 1998-05-05 J. Uriach & Cia S.A. Azo derivatives of 5-aminosalicylic acid

Also Published As

Publication number Publication date
NO20024878L (no) 2002-12-05
WO2001077109A2 (fr) 2001-10-18
CY1107090T1 (el) 2012-10-24
EP1272490B1 (fr) 2007-09-12
PT1272490E (pt) 2007-11-08
NO323955B1 (no) 2007-07-23
JP2003530397A (ja) 2003-10-14
AU2001273937A1 (en) 2001-10-23
CA2405741A1 (fr) 2001-10-18
AR033363A1 (es) 2003-12-17
KR20080053417A (ko) 2008-06-12
ES2291320T3 (es) 2008-03-01
BR0109935A (pt) 2003-05-27
ATE372999T1 (de) 2007-09-15
EP1272490A2 (fr) 2003-01-08
HK1052184A1 (en) 2003-09-05
WO2001077109A3 (fr) 2001-12-27
KR100933646B1 (ko) 2009-12-23
MXPA02009934A (es) 2004-08-19
US20030176401A1 (en) 2003-09-18
DK1272490T3 (da) 2008-01-21
DE60130444T2 (de) 2008-06-05
JP4597463B2 (ja) 2010-12-15
JP2010159293A (ja) 2010-07-22
NO20024878D0 (no) 2002-10-09
HK1052184B (zh) 2007-11-16
US6809087B2 (en) 2004-10-26
ES2165803A1 (es) 2002-03-16
KR20020084306A (ko) 2002-11-05
KR100859296B1 (ko) 2008-09-19
ES2165803B1 (es) 2003-09-16
DE60130444D1 (de) 2007-10-25

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Effective date: 20150410