CA2400526C - Method and apparatus for destroying dividing cells - Google Patents
Method and apparatus for destroying dividing cells Download PDFInfo
- Publication number
- CA2400526C CA2400526C CA2400526A CA2400526A CA2400526C CA 2400526 C CA2400526 C CA 2400526C CA 2400526 A CA2400526 A CA 2400526A CA 2400526 A CA2400526 A CA 2400526A CA 2400526 C CA2400526 C CA 2400526C
- Authority
- CA
- Canada
- Prior art keywords
- electric field
- cells
- dividing cells
- cell
- dividing
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/326—Applying electric currents by contact electrodes alternating or intermittent currents for promoting growth of cells, e.g. bone cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/20—Applying electric currents by contact electrodes continuous direct currents
- A61N1/205—Applying electric currents by contact electrodes continuous direct currents for promoting a biological process
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00571—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
- A61B2018/00613—Irreversible electroporation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
- A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
- A61B18/14—Probes or electrodes therefor
- A61B2018/147—Electrodes transferring energy by capacitive coupling, i.e. with a dielectricum between electrode and target tissue
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Cell Biology (AREA)
- Molecular Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US18329500P | 2000-02-17 | 2000-02-17 | |
| US60/183,295 | 2000-02-17 | ||
| PCT/IB2001/000202 WO2001060994A1 (en) | 2000-02-17 | 2001-02-16 | Method and apparatus for destroying dividing cells |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2400526A1 CA2400526A1 (en) | 2001-08-23 |
| CA2400526C true CA2400526C (en) | 2013-04-23 |
Family
ID=22672230
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA2400526A Expired - Lifetime CA2400526C (en) | 2000-02-17 | 2001-02-16 | Method and apparatus for destroying dividing cells |
Country Status (7)
| Country | Link |
|---|---|
| US (2) | US7333852B2 (enExample) |
| EP (2) | EP2335776A1 (enExample) |
| JP (1) | JP5280600B2 (enExample) |
| CN (1) | CN1416466A (enExample) |
| AU (1) | AU3399801A (enExample) |
| CA (1) | CA2400526C (enExample) |
| WO (1) | WO2001060994A1 (enExample) |
Families Citing this family (151)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7089054B2 (en) | 2002-10-02 | 2006-08-08 | Standen Ltd. | Apparatus and method for treating a tumor or the like |
| EP2335776A1 (en) | 2000-02-17 | 2011-06-22 | Yoram Palti | Method and apparatus for destroying dividing cells |
| US7599746B2 (en) | 2000-02-17 | 2009-10-06 | Standen Ltd | Apparatus and method for preventing the spread of cancerous metastases and for elimination of metastases |
| US8175698B2 (en) | 2000-02-17 | 2012-05-08 | Novocure Ltd. | Treating bacteria with electric fields |
| US8447395B2 (en) | 2000-02-17 | 2013-05-21 | Novocure Ltd | Treating bacteria with electric fields |
| US7599745B2 (en) | 2000-02-17 | 2009-10-06 | Standen Ltd | Treating a tumor or the like with an electric field |
| US7136699B2 (en) * | 2002-10-02 | 2006-11-14 | Standen, Ltd. | Apparatus for destroying dividing cells |
| US6868289B2 (en) * | 2002-10-02 | 2005-03-15 | Standen Ltd. | Apparatus for treating a tumor or the like and articles incorporating the apparatus for treatment of the tumor |
| US7146210B2 (en) | 2000-02-17 | 2006-12-05 | Standen Ltd. | Apparatus and method for optimizing tumor treatment efficiency by electric fields |
| US7016725B2 (en) | 2001-11-06 | 2006-03-21 | Standen Ltd. | Method and apparatus for destroying dividing cells |
| ES2344215T3 (es) | 2004-12-07 | 2010-08-20 | Standen Ltd. | Electrodos para aplicar un campo electrico in vivo durante un dilatado periodo de tiempo. |
| JP5559460B2 (ja) * | 2004-12-27 | 2014-07-23 | スタンデン・リミテッド | 異なる配向の電界を用いて腫瘍またはその類似物を処理する方法 |
| US20070021803A1 (en) | 2005-07-22 | 2007-01-25 | The Foundry Inc. | Systems and methods for neuromodulation for treatment of pain and other disorders associated with nerve conduction |
| CA2624624C (en) * | 2005-10-03 | 2016-07-19 | Novocure Limited | Optimizing characteristics of an electric field to increase the field's effect on proliferating cells |
| US8019414B2 (en) | 2006-04-05 | 2011-09-13 | Novocure Ltd. | Treating cancer using electromagnetic fields in combination with other treatment regimens |
| JP5457183B2 (ja) * | 2006-09-14 | 2014-04-02 | ラジュール・テクノロジーズ・エルエルシイ | 癌細胞を破壊する装置及び方法 |
| JP2010534056A (ja) * | 2007-02-16 | 2010-11-04 | イオジェニックス・プロプライエタリー・リミテッド | 水生生物の培養を改善するための方法 |
| WO2009044289A1 (en) * | 2007-03-06 | 2009-04-09 | Novocure Ltd. | Treating cancer using electromagnetic fields in combination with photodynamic therapy |
| CN101820947A (zh) * | 2007-08-14 | 2010-09-01 | 诺沃库勒有限公司 | 用电场治疗寄生物 |
| WO2009036472A1 (en) * | 2007-09-14 | 2009-03-19 | Lazure Technologies, Llc | Prostate cancer ablation |
| WO2009036459A1 (en) * | 2007-09-14 | 2009-03-19 | Lazure Technologies, Llc | Multi-tine probe and treatment by activation of opposing tines |
| WO2009036457A1 (en) * | 2007-09-14 | 2009-03-19 | Lazure Technologies, Llc | Multi-layer electrode ablation probe and related methods |
| US20100100093A1 (en) * | 2008-09-16 | 2010-04-22 | Lazure Technologies, Llc. | System and method for controlled tissue heating for destruction of cancerous cells |
| US8728139B2 (en) | 2009-04-16 | 2014-05-20 | Lazure Technologies, Llc | System and method for energy delivery to a tissue using an electrode array |
| US9526911B1 (en) | 2010-04-27 | 2016-12-27 | Lazure Scientific, Inc. | Immune mediated cancer cell destruction, systems and methods |
| US9233257B1 (en) | 2010-11-22 | 2016-01-12 | Jacob Zabara | Electromagnetic radiation treatment |
| US8684901B1 (en) | 2010-11-22 | 2014-04-01 | Jacob Zabara | Electromagnetic radiation treatment for cancer and pathological genetic regulations |
| AU2012364909B2 (en) | 2011-02-15 | 2016-11-24 | Hemosonics, Llc | Characterization of blood hemostasis and oxygen transport parameters |
| US9789328B2 (en) * | 2012-10-26 | 2017-10-17 | Robert E. Sandstrom | Tumor treatment with free radical lifetimes enhanced by persistent low strength magnetic field |
| US9757582B2 (en) * | 2012-10-26 | 2017-09-12 | Robert E. Sandstrom | Tumor treatment with free radical lifetimes enhanced by persistant low strength magnetic field |
| US9655669B2 (en) | 2013-05-06 | 2017-05-23 | Novocure Limited | Optimizing treatment using TTFields by changing the frequency during the course of long term tumor treatment |
| US10779875B2 (en) | 2013-05-06 | 2020-09-22 | Novocure Gmbh | Optimizing treatment using TTfields by changing the frequency during the course of long term tumor treatment |
| US20190117963A1 (en) | 2014-07-25 | 2019-04-25 | Loyalty Based Innovations, LLC | Apparatus and method for treating multiple tumors in patients with metastatic disease by electric fields |
| US9833617B2 (en) | 2014-07-25 | 2017-12-05 | Loyalty Based Innovations, LLC | Apparatus and method for treating multiple tumors in patients with metastatic disease by electric fields |
| US9726647B2 (en) | 2015-03-17 | 2017-08-08 | Hemosonics, Llc | Determining mechanical properties via ultrasound-induced resonance |
| US10188851B2 (en) | 2015-10-28 | 2019-01-29 | Novocure Limited | TTField treatment with optimization of electrode positions on the head based on MRI-based conductivity measurements |
| US10821283B2 (en) | 2016-04-04 | 2020-11-03 | Novocure Gmbh | Reducing motility of cancer cells using tumor treating fields (TTFields) |
| US20180001075A1 (en) | 2016-06-30 | 2018-01-04 | Novocure Limited | Arrays for Longitudinal Delivery of TTFields to a Body |
| WO2018134733A1 (en) | 2017-01-19 | 2018-07-26 | Moshe Giladi | System for viewing cell cultures under a microscope whilst applying ttfields |
| US11338135B2 (en) | 2017-10-23 | 2022-05-24 | Cardiac Pacemakers, Inc. | Medical devices for cancer therapy with electric field shaping elements |
| US12403306B2 (en) | 2017-10-23 | 2025-09-02 | Cardiac Pacemakers, Inc. | Electric field shaping leads for treatment of cancer |
| CO2018001283A1 (es) | 2018-02-07 | 2019-08-09 | Panacea Quantum Leap Tech Llc | Método de estimulación de tejidos con campos eléctricos y magnéticos por barrido en frecuencia |
| US10953209B2 (en) | 2018-03-28 | 2021-03-23 | Board Of Regents Of The University Of Texas System | Treating tumors using TTFields combined with a PARP inhibitor |
| EP3773726B1 (en) | 2018-04-09 | 2024-06-05 | Novocure GmbH | Treating tumors with ttfields and an aurora kinase inhibitor |
| EP3775956B1 (en) | 2018-04-10 | 2022-03-23 | Novocure GmbH | Low frequency (<1 mhz) ac conductivity estimates derived from two mri images having different repetition times |
| ES3047748T3 (en) | 2018-07-03 | 2025-12-04 | Univ Leland Stanford Junior | Using alternating electric fields to increase cell membrane permeability |
| US11179322B2 (en) | 2018-07-10 | 2021-11-23 | Novocure Gmbh | Methods and compositions for treating tumors with TTFields and sorafenib |
| KR102794415B1 (ko) | 2018-07-10 | 2025-04-09 | 노보큐어 게엠베하 | 교류 전기장을 사용한 바이러스 감염 억제 |
| MX2020013431A (es) | 2018-07-18 | 2021-05-27 | Novocure Gmbh | Uso de densidad de perdida de potencia y mediciones relacionadas para cuantificar la dosis de campos de tratamiento de tumores (ttfield). |
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-
2001
- 2001-02-16 EP EP10012031A patent/EP2335776A1/en not_active Ceased
- 2001-02-16 JP JP2001560365A patent/JP5280600B2/ja not_active Expired - Lifetime
- 2001-02-16 US US10/204,334 patent/US7333852B2/en not_active Ceased
- 2001-02-16 CN CN01806416A patent/CN1416466A/zh active Pending
- 2001-02-16 US US12/199,498 patent/USRE43618E1/en not_active Expired - Lifetime
- 2001-02-16 WO PCT/IB2001/000202 patent/WO2001060994A1/en not_active Ceased
- 2001-02-16 CA CA2400526A patent/CA2400526C/en not_active Expired - Lifetime
- 2001-02-16 AU AU33998/01A patent/AU3399801A/en not_active Abandoned
- 2001-02-16 EP EP01906036A patent/EP1259596A4/en not_active Ceased
Also Published As
| Publication number | Publication date |
|---|---|
| EP1259596A4 (en) | 2004-12-22 |
| US7333852B2 (en) | 2008-02-19 |
| JP5280600B2 (ja) | 2013-09-04 |
| AU3399801A (en) | 2001-08-27 |
| USRE43618E1 (en) | 2012-08-28 |
| EP2335776A1 (en) | 2011-06-22 |
| CA2400526A1 (en) | 2001-08-23 |
| WO2001060994A1 (en) | 2001-08-23 |
| CN1416466A (zh) | 2003-05-07 |
| JP2004505604A (ja) | 2004-02-26 |
| EP1259596A1 (en) | 2002-11-27 |
| US20030150372A1 (en) | 2003-08-14 |
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